Segment information (Details) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
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Jun. 30, 2026
USD ($)
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Mar. 31, 2026
USD ($)
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Jun. 30, 2025
USD ($)
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Mar. 31, 2025
USD ($)
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Jun. 30, 2026
USD ($)
Segment
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Jun. 30, 2025
USD ($)
|
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| Segment Reporting Information [Line Items] | ||||||
| Number of operating segments | Segment | 1 | |||||
| Number of reportable segments | Segment | 1 | |||||
| Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description | The CODM assesses performance for the segment based on net loss, which is reported on the condensed consolidated statements of operations and comprehensive loss as net loss. The measure of segment assets is reported on the condensed consolidated balance sheets as total assets. When evaluating the Company’s financial performance, the CODM regularly reviews total revenues, total expenses and research and development expenses by program. | |||||
| Collaboration revenue | $ 0 | $ 4,015 | $ 0 | $ 6,941 | ||
| Less: | ||||||
| General and administrative | (18,250) | (10,042) | (31,200) | (20,732) | ||
| Total operating expenses | (78,135) | (50,493) | (137,466) | (98,055) | ||
| Loss from operations | (78,135) | (46,478) | (137,466) | (91,114) | ||
| Interest income | 5,008 | 3,081 | 10,500 | 6,077 | ||
| Net loss | (73,127) | $ (53,839) | (43,397) | $ (41,640) | (126,966) | (85,037) |
| Single reportable segment | ||||||
| Segment Reporting Information [Line Items] | ||||||
| Collaboration revenue | 4,015 | 6,941 | ||||
| Less: | ||||||
| Other direct research and development | 13,865 | 5,493 | 23,836 | 10,165 | ||
| Indirect research and development | 20,393 | 13,115 | 36,707 | 23,453 | ||
| General and administrative | 13,472 | 6,873 | 22,121 | 14,248 | ||
| Other segment expenses | 9,756 | 5,983 | 18,312 | 12,298 | ||
| Total operating expenses | 78,135 | 50,493 | 137,466 | 98,055 | ||
| Loss from operations | (78,135) | (46,478) | (137,466) | (91,114) | ||
| Interest income | 5,008 | 3,081 | 10,500 | 6,077 | ||
| Net loss | (73,127) | (43,397) | (126,966) | (85,037) | ||
| Single reportable segment | Varegacestat | ||||||
| Less: | ||||||
| Direct research and development expenses | 10,717 | 12,733 | 20,549 | 27,120 | ||
| Single reportable segment | IM-1021 | ||||||
| Less: | ||||||
| Direct research and development expenses | 6,347 | 1,728 | 10,211 | 4,795 | ||
| Single reportable segment | IM-1617 | ||||||
| Less: | ||||||
| Direct research and development expenses | 2,029 | 3,556 | 2,867 | 3,931 | ||
| Single reportable segment | IM-3050 | ||||||
| Less: | ||||||
| Direct research and development expenses | $ 1,556 | $ 1,012 | $ 2,863 | $ 2,045 | ||
| X | ||||||||||
- Definition Amount of research and development expense directly attributable to the acquired in-process research and development program. No definition available.
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| X | ||||||||||
- Definition Amount of research and development expense not directly attributable to particular product candidate but for the devision as a whole. No definition available.
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| X | ||||||||||
- Definition Other direct research and development. No definition available.
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| X | ||||||||||
- Definition Other segment expenses. No definition available.
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| X | ||||||||||
- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount of interest income (expense) classified as operating. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Number of segments reported by the entity. A reportable segment is a component of an entity for which there is an accounting requirement to report separate financial information on that component in the entity's financial statements. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Description of how chief operating decision maker (CODM) uses reported segment profit (loss) measure to assess performance and allocate resource. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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