Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Trading Arrangement: Trading Arrangement [Axis] Maximum Maximum [Member] Statistical Measurement Statistical Measurement [Domain] Title of 12(b) Security Title of 12(b) Security Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-Sale [Table] Document Fiscal Year Focus Document Fiscal Year Focus Adjustment to Compensation, Amount Adjustment to Compensation Amount Financial Instrument [Axis] Financial Instrument [Axis] Restricted Stock Units Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Segment Reporting [Abstract] Released (in shares) Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Releases in Period Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Releases in Period Common stock, $0.0001 par value per share; 300,000,000 shares authorized at June 30, 2026 and December 31, 2025; and 61,920,154 and 61,449,290 shares issued and outstanding at June 30, 2026 and December 31, 2025, respectively (Note 9) Common Stock, Value, Issued 2027 Lessee, Operating Lease, Liability, to be Paid, Year One Accrued compensation and benefits Employee-related Liabilities, Current 2020 Stock Options and Incentive Plan and 2022 Inducement Plan Two Thousand And Twenty Stock Options And Incentive Plan And Two Thousand Twenty Two Inducement Plan [Member] Two Thousand And Twenty Stock Options And Incentive Plan And Two Thousand Twenty Two Inducement Plan Other Other Prepaid Expense, Current Restatement Determination Date Restatement Determination Date Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Measurement Frequency Measurement Frequency [Axis] Weighted- average exercise price per share, vested and expected to vest (USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Warrant, Acquiring Person's beneficial ownership threshold, non-passive investor Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Non-Passive Investor Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Non-Passive Investor Interest and other income (expense), net Interest and other (income) expense, net Interest And Other Income (Expense), Net Interest And Other Income (Expense), Net Amendment Flag Amendment Flag Current liabilities Liabilities, Current [Abstract] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Class of Warrant or Right [Table] Class of Warrant or Right [Table] Shares of common stock available for future grants under the 2020 Stock Option and Incentive Plan Two Thousand And Twenty Stock Options And Incentive Plan [Member] 2020 Stock options and incentive plan. Prepaid licenses Prepaid Licenses, Current Prepaid Licenses, Current Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Underlying common stock fair value (USD per share) Underlying Common Stock Fair Value Underlying common stock fair value. Leases [Abstract] Leases [Abstract] Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Total property and equipment held for sale Disposal Group, Including Discontinued Operation, Property, Plant, and Equipment Property, Plant, and Equipment [Abstract] Property, Plant, and Equipment [Abstract] Entity Address, State or Province Entity Address, State or Province Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Incentive Stock Options and Nonqualified Stock Options Incentive Stock Options And Nonqualified Stock Options [Member] Incentive stock options and nonqualified stock options. PEO Total Compensation Amount PEO Total Compensation Amount Stock options and ESPP Employee Stock Option And Purchase Plan [Member] Employee stock option and purchase plan. Common stock, par value (USD per share) Common Stock, Par or Stated Value Per Share Outstanding and unvested, beginning balance (in shares) Outstanding and unvested, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Shares used in computing net loss per share - basic (in shares) Weighted Average Number of Shares Outstanding, Basic Retirement Benefits [Abstract] Retirement Benefits [Abstract] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Fair Value, by Balance Sheet Grouping [Table] Fair Value, by Balance Sheet Grouping [Table] Number of reportable segments Number of Reportable Segments Total current liabilities Liabilities, Current 2030 Lessee, Operating Lease, Liability, to be Paid, Year Four Adjusted Cost Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss Comprehensive loss: Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Entity Address, City or Town Entity Address, City or Town Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Document Information [Line Items] Document Information [Line Items] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Class of Stock [Axis] Class of Stock [Axis] Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Schedule of Weighted-average Remaining Lease Terms and Discount Rates Assets And Liabilities, Lessee [Table Text Block] Assets And Liabilities, Lessee Level 2 Fair Value, Inputs, Level 2 [Member] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Common Stock, par value $0.0001 per share Common Stock, Par Value $0.0001 Per Share [Member] Common Stock, Par Value $0.0001 Per Share Schedule of Long-Term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Accounting Pronouncements Not Yet Adopted New Accounting Pronouncements, Policy [Policy Text Block] Purchase of property and equipment in accounts payable and accrued liabilities Capital Expenditures Incurred but Not yet Paid Schedule of Segment Reporting Expenses Segment Reporting [Table Text Block] Gain on sale of property and equipment Gain (Loss) on Disposition of Property Plant Equipment Use of Estimates Use of Estimates, Policy [Policy Text Block] Related Party Related and Nonrelated Parties [Axis] Number of shares per right entitled to purchase (in shares) Number Of Shares Per Right Entitled To Purchase Number Of Shares Per Right Entitled To Purchase Total other comprehensive loss Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Schedule of Accrued Liabilities Schedule of Accrued Liabilities [Table Text Block] Exercise price (USD per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Long-term debt (Note 7) Debt outstanding Long-Term Debt Property and Equipment, net Property, Plant, and Equipment [Text Block] Schedule of Operating Lease Liability Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Supplemental disclosures of noncash investing activities: Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Number of classes of stock authorized Number Of Classes Of Stock Authorized Number Of Classes Of Stock Authorized Document Period End Date Document Period End Date Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Employee-related expenses - research and development (excluding stock-based compensation) Research And Development Expense, Adjusted Research And Development Expense, Adjusted Net cash provided by investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Released (USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Released, Weighted Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Released, Weighted Average Grant Date Fair Value Other Significant Noncash Transactions [Line Items] Other Significant Noncash Transactions [Line Items] Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Term loan facility Debt Instrument, Face Amount 2028 Lessee, Operating Lease, Liability, to be Paid, Year Two Preferred Stock Common Stock Stockholder Rights Agreement Equity [Text Block] Security Exchange Name Security Exchange Name Granted (USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax Entity Shell Company Entity Shell Company Operating lease liabilities, current (Note 15) Total current operating lease liabilities Operating Lease, Liability, Current Schedule of Property and Equipment, Net Property, Plant, and Equipment [Table Text Block] Net Loss Per Share Attributable to Common Stockholders Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Earnings Per Share [Abstract] Earnings Per Share [Abstract] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Total liabilities Liabilities Trading Symbol Trading Symbol 2015 Equity and 2020 Incentive Plan Two Thousand Fifteen And Two Thousand Twenty Equity Incentive Plan [Member] Two thousand fifteen and two thousand twenty equity incentive plan . Market Value Debt Securities, Available-for-Sale, Excluding Accrued Interest Geographical Geographical [Domain] Purchase of property and equipment Payments to Acquire Property, Plant, and Equipment Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Unrecognized compensation cost Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Company Selected Measure Name Company Selected Measure Name Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] U.S. Government agency securities US Government Corporations and Agencies Securities [Member] Credit Facility [Domain] Credit Facility [Domain] Schedule of Cash and Cash Equivalents, Money Market Funds and Short-term Investments by Significant Investment Category Cash, Cash Equivalent, and Investment [Table Text Block] Cash flows from operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Compensation Amount Outstanding Recovery Compensation Amount Individual: Individual [Axis] Shares used in computing net loss per share - diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Executive Officer Executive Officer [Member] Dividends paid (USD per share) Common Stock, Dividends, Per Share, Cash Paid Entity Emerging Growth Company Entity Emerging Growth Company Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Warrant, exercisable after beneficial ownership threshold announcement, number of days Class Of Warrant Or Right, Exercisable After Beneficial Ownership Threshold Announcement, Number Of Days Class Of Warrant Or Right, Exercisable After Beneficial Ownership Threshold Announcement, Number Of Days Underlying Security Market Price Change Underlying Security Market Price Change, Percent Temporary Equity Disclosure [Abstract] Temporary Equity Disclosure [Abstract] Line of credit facility, current borrowing capacity Proceeds from Lines of Credit U.S. Treasury securities US Treasury Securities [Member] Less: Present value discount Lessee, Operating Lease, Liability, Undiscounted Excess Amount Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Other non-current assets Increase (Decrease) in Other Noncurrent Assets Schedule of Laboratory Equipment Assets Held for Sale Long-Lived Asset, Held-for-Sale [Table Text Block] Award Timing Predetermined Award Timing Predetermined [Flag] Debt Securities, Available-for-sale [Line Items] Debt Securities, Available-for-Sale [Line Items] Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Level 1 Fair Value, Inputs, Level 1 [Member] Effective tax rate Effective Income Tax Rate Reconciliation, Percent Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Future lease payments Total undiscounted lease payments Lessee, Operating Lease, Liability, to be Paid Unvested and outstanding, beginning balance (USD per share) Unvested and outstanding, ending balance (USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value All Executive Categories All Executive Categories [Member] Operating lease liabilities Increase (Decrease) in Operating Lease Liability Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Preferred stock, par value (USD per share) Preferred Stock, Par or Stated Value Per Share Class of Warrant or Right [Line Items] Class of Warrant or Right [Line Items] Depreciation expense Depreciation Plan Name Plan Name [Domain] Antidilutive Securities Antidilutive Securities [Axis] Outstanding, beginning balance (USD per share) Outstanding, ending balance (USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Operating lease right-of-use assets (Note 15) Operating Lease, Right-of-Use Asset Lease term extension period Lessee, Operating Lease, Renewal Term Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Risk-free interest rate, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Debt Disclosure [Abstract] Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Issuance of common stock under benefit plans Stock Issued During Period, Value, Employee Benefit Plan Segments Segment Reporting [Text Block] Minimum Minimum [Member] Line of credit Long-Term Line of Credit Expiration Date Trading Arrangement Expiration Date Accrued research and development Accrued Research And Development Expenses, Current Accrued research and development expenses, current Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Income Statement Location Location, Statement of Income, Balance [Axis] Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Weighted- average remaining contractual term (in years), outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Liabilities measured at fair value Financial Liabilities Fair Value Disclosure Number of options, exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Common stock, shares authorized (in shares) Common Stock, Shares Authorized Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Schedule of Restricted Stock Activity Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Exercise Price Award Exercise Price Supplemental disclosures of cash flow information: Supplemental Cash Flow Disclosures [Abstract] Supplemental Cash Flow Disclosures Abstract Cash flows from investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Fair Value, Recurring Fair Value, Recurring [Member] Segment Reporting [Line Items] Segment Reporting [Line Items] Document Quarterly Report Document Quarterly Report Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Segments [Domain] Segments [Domain] Lender Name [Axis] Lender Name [Axis] Long-term Debt Debt Disclosure [Text Block] Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Restructuring reserve Restructuring Reserve Equity Component Equity Component [Domain] PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Adoption Date Trading Arrangement Adoption Date Counterparty Name Counterparty Name [Domain] Total stockholders’ equity Beginning balance Ending balance Equity, Attributable to Parent Restructuring Type [Axis] Restructuring Type [Axis] Landlord Landlord [Member] Landlord Prepaid insurance Prepaid Insurance Assets Assets [Abstract] Other Significant Noncash Transactions [Table] Other Significant Noncash Transactions [Table] Title Trading Arrangement, Individual Title Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Accounting Policies [Abstract] Accounting Policies [Abstract] Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Total discounted lease payments Operating Lease, Liability Fair Value Measurements, Non-recurring Basis Fair Value, Nonrecurring [Member] Insider Trading Policies and Procedures [Line Items] Outstanding, beginning balance (in shares) Outstanding, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Accrued Liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Prepaid expenses and other current assets (Note 5) Total prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Repayments of debt Repayments of Debt Common stock shares outstanding percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum Type of Restructuring [Domain] Type of Restructuring [Domain] Letter of Credit Letter of Credit [Member] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Number of operating segments Number of Operating Segments Vesting of RSUs Restricted Stock Units Restricted stock units Restricted Stock Units (RSUs) [Member] Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Entity Central Index Key Entity Central Index Key Less: Accumulated depreciation Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization Additional paid-in capital Additional Paid in Capital, Common Stock All Adjustments to Compensation All Adjustments to Compensation [Member] Equity [Abstract] Equity [Abstract] Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Income Statement [Abstract] Income Statement [Abstract] Stockholders’ equity Equity, Attributable to Parent [Abstract] Document Transition Report Document Transition Report Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Axis] Operating expenses: Operating expenses: Operating Expenses [Abstract] Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Shares of common stock available for future grants under the 2022 Inducement Plan Two Thousand And Twenty Two Inducement Plan [Member] Two Thousand And Twenty Two Inducement Plan Schedule of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for Stock Option Awards Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Number of Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] City Area Code City Area Code Accumulated Other Comprehensive Gain/(Loss) AOCI Attributable to Parent [Member] Document Information [Table] Document Information [Table] All Individuals All Individuals [Member] Non-cash operating lease expense Operating Lease, Right-of-Use Asset, Periodic Reduction Name Forgone Recovery, Individual Name Unrecognized compensation expense, weighted average period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Weighted Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Statement [Line Items] Statement [Line Items] Total assets Assets Operating Lease Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Total shares reserved for future issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Schedule of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for 2020 Employee Stock Purchase Plan Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Interest expense Interest expense Interest Expense, Nonoperating Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Equity Incentive Plans and Stock-Based Compensation Share-Based Payment Arrangement [Text Block] Other accrued liabilities Accounts Payable and Other Accrued Liabilities, Current PEO PEO [Member] Cash and Cash Equivalents Cash and Cash Equivalents [Domain] Total stock-based compensation expense Share-Based Payment Arrangement, Expense Cash equivalents Cash Equivalents [Member] Rights Agreement Rights Agreement [Member] Rights Agreement Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Granted (USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Cash and cash equivalents Cash Equivalents, at Carrying Value Accumulated Deficit Retained Earnings [Member] Operating lease liabilities, non-current (Note 15) Total non-current operating lease liabilities Operating Lease, Liability, Noncurrent Total operating expenses Operating Expenses Money Market Funds Money Market Funds [Member] Forfeited (USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Net unrealized loss on short-term investments Net unrealized loss on short-term investments OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Common stock, shares outstanding (in shares) Beginning balance (in shares) Ending balance (in shares) Common Stock, Shares, Outstanding Award Timing Disclosures [Line Items] Corporate debt securities Corporate Debt Securities [Member] Net loss per share - diluted (USD per share) Earnings Per Share, Diluted Entity Current Reporting Status Entity Current Reporting Status Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Expected volatility, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Total Shareholder Return Amount Total Shareholder Return Amount Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Research and development Research and Development Expense Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Cash flows from financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Property and equipment, net (Note 4) Total property and equipment, net Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Financial Instruments [Domain] Financial Instruments [Domain] Term Loan Facility Term Loan Facility [Member] Term Loan Facility Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Leased premises under non cancelable operating lease Leased Space Under Non Cancellable Operating Lease Leased space under non cancellable operating lease. Underlying Securities Award Underlying Securities Amount Purchase of short-term investments Payments to Acquire Short-Term Investments Forfeited (USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Financial Instruments Financial Instruments Disclosure [Text Block] Construction-in-progress Construction in Progress [Member] Weighted-average discount rate Operating Lease, Weighted Average Discount Rate, Percent Risk-free interest rate, minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Segment Reporting [Table] Segment Reporting [Table] Percentage of payroll deductions Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate Property and equipment held for sale (Note 4) Disposal Group, Including Discontinued Operation, Property, Plant, and Equipment, Current Weighted- Average Remaining Contractual Term (in Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Schedule of Operating and Variable Lease Cost Lease, Cost [Table Text Block] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] All Trading Arrangements All Trading Arrangements [Member] Other Performance Measure, Amount Other Performance Measure, Amount Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Loss from operations Segment loss Operating Income (Loss) Current Fiscal Year End Date Current Fiscal Year End Date Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Dividends declared (USD per share) Common Stock, Dividends, Per Share, Declared Entity File Number Entity File Number Prepaid research and development Prepaid Research And Development, Current Prepaid Research And Development, Current Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Schedule of Option Activity Under the 2015 Plan and 2020 Plan Share-Based Payment Arrangement, Option, Activity [Table Text Block] Weighted- Average Exercise Price per Share Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Common stock, shares issued (in shares) Common Stock, Shares, Issued Measure: Measure [Axis] Series A Junior Participating Preferred Purchase Rights Series A Junior Participating Preferred Purchase Rights [Member] Series A Junior Participating Preferred Purchase Rights Organization and Description of Business Business Description and Basis of Presentation [Text Block] Equity Components Equity Components [Axis] Class of Stock [Line Items] Class of Stock [Line Items] California CALIFORNIA Entity Interactive Data Current Entity Interactive Data Current Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Payment made under defined contribution plan Defined Contribution Plan, Cost Entity Small Business Entity Small Business Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent 2029 Lessee, Operating Lease, Liability, to be Paid, Year Three Termination Date Trading Arrangement Termination Date Property, Plant, and Equipment [Line Items] Property, Plant, and Equipment [Line Items] Repriced Options Share-Based Compensation Arrangement, Options, Repriced [Member] Share-Based Compensation Arrangement, Options, Repriced Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Expiration period from date of grant Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Other non-current assets Other Assets, Noncurrent Line of Credit Facility, Lender [Domain] Line of Credit Facility, Lender [Domain] Document Type Document Type Accrued liabilities (Note 6) Total accrued liabilities Accrued Liabilities, Current Fair Value as of Grant Date Award Grant Date Fair Value Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Employee Employee [Member] Employee Reconciliation of cash, cash equivalents, and restricted cash reported in the balance sheets Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation [Abstract] Aggregate intrinsic value, exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Arrangement Duration Trading Arrangement Duration Warrant, Acquiring Person's beneficial ownership threshold, passive investor Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Passive Investor Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Passive Investor Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Local Phone Number Local Phone Number Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Registrant Name Entity Registrant Name Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Aggregate intrinsic value, vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Commitments and Contingencies (Note 14) Commitments and Contingencies Common stock, voting rights, number of votes per share Number Of Votes Per Each Share Of Common Stock Number Of Votes Per Each Share Of Common Stock Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Total property and equipment, gross Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Executive Category: Executive Category [Axis] Vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Counterparty Name Counterparty Name [Axis] Furniture and fixtures Furniture and Fixtures [Member] Liabilities and stockholders’ equity Liabilities and Equity [Abstract] Weighted- average remaining contractual term (in years), exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term Award Type Award Type [Domain] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount 2026 (remainder of the year) Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Fair Value, Inputs, Level 3 Fair Value, Inputs, Level 3 [Member] Bexotegrast - clinical trial and third party contracting costs Clinical Trial And Third Party Contracting Costs Clinical Trial And Third Party Contracting Costs Expected term (in years) Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Lease term Lessee, Operating Lease, Term of Contract PEO Name PEO Name Geographical Geographical [Axis] Accrued liabilities Increase (Decrease) in Accrued Liabilities Leasehold improvements Leasehold Improvements [Member] Restricted cash Restricted Cash Other segment items Segment Reporting, Other Segment Item, Amount Long-Lived Asset, Class Long-Lived Asset, Class [Axis] Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Entity Tax Identification Number Entity Tax Identification Number Interest expense, debt Interest Expense, Debt Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Payments for restructuring Payments for Restructuring Exercised (USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Cash and cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Total cash, cash equivalents, and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, 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Restatement Determination Date: Restatement Determination Date [Axis] Weighted- average exercise price per share, exercisable (USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Cash and Cash Equivalents Cash and Cash Equivalents [Axis] Defined Contribution Plan Defined Contribution Plan [Text Block] Schedule of Prepaid Expenses and Other Current Assets Schedule Of Prepaid Expenses And Other Current Assets [Table Text Block] Schedule Of Prepaid Expenses And Other Current Assets Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]