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Note 7 - Collaborations and License Agreements (Details Textual)		3 Months Ended			6 Months Ended		36 Months Ended
	Oct. 27, 2022 USD ($)	Jun. 30, 2026 USD ($) Agreement	Dec. 31, 2025 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2026 USD ($) Agreement	Jun. 30, 2025 USD ($)	Dec. 16, 2023 USD ($)	Dec. 31, 2024 USD ($)	Oct. 20, 2023 Agreement
Collaborations and license agreements upfront fee	$ 0				$ 1,000,000
Royalty expense					6,750,000		$ 4,500,000
Milestone payment					500,000
Accounts receivable		$ 500,000	$ 0	$ 0	500,000	$ 0		$ 0
Maximum Aggregate Consideration							5,000,000
Milestone payment in cash			$ 235,000
License Revenue		0.5		0	0.5	0
Milestone payments							$ 1,500,000
Research and development expense		6,000,000			12,000,000
Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
Net credit related to the Giiant Development Plan		$ 0			$ 0	600,000
Joint development expenses				22,000,000,000
License Agreements with the Regents of the University of California [Member]
Number of license agreements \| Agreement		3			3
Number of terminated license agreements \| Agreement									2
Sublicense fees		$ 0		$ 0	$ 0	$ 0
License Agreements with the Regents of the University of California [Member] \| Maximum [Member]
Royalty rate, portion of sublicense income to be paid, percentage of one-third of upfront payment and milestone payment received		35.00%			35.00%
License Agreements with the Regents of the University of California [Member] \| Minimum [Member]
Royalty rate, portion of sublicense income to be paid, percentage of one-third of upfront payment and milestone payment received		30.00%			30.00%
NSI-532.IGF-1 [Member]
Percentage cost in patent right	100.00%
Percentage of net revenue	50.00%