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Open Market Sale Agreement [Member] Open Market Sale Agreement Other Research and Development Expense Other R&D costs Other R&D costs Restructuring Reserve Restructuring Reserve, Ending Balance Restructuring Reserve, Beginning Balance Restructuring Reserve, Total Restructuring remaining accrual Entity Incorporation, State or Country Code Options exercised thirteen. Options Exercised Thirteen [Member] Options exercised at $13.80/ADS or $4.60/ordinary share Entity Current Reporting Status Collaboration agreement with AstraZeneca. Collaboration Agreement With AstraZeneca [Member] Collaboration Agreement with AstraZeneca Product and Service [Axis] Document Fiscal Period Focus Revenue from Contract with Customer [Abstract] Entity Shell Company Cash and Cash Equivalent Cash and cash equivalents Total Cash and cash equivalents Goodwill Disclosure [Text Block] Goodwill Redemption of term deposits. Redemption Of Term Deposits Redemption of term deposits Common Stock, Shares, Issued Shares issued Research collaboration AstraZeneca. Research Collaboration Astra Zeneca [Member] Research Collaboration - AstraZeneca Statement [Table] Statement [Line Items] Entity Filer Category Options exercised sixteen. Options Exercised Sixteen [Member] Options exercised at $19.50/ADS or $6.50/ordinary share Liabilities and Equity Total liabilities and shareholders' equity Total liabilities and shareholders' equity Amortization Amortization expense Amortization, Total Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted Average Exercise Price, Exercisable at the year-end Goodwill Goodwill Goodwill, Total Balance at January, 1 Balance at end of year Geographical [Domain] Payments to Acquire Intangible Assets Purchase of intangible assets Additional Paid in Capital, Common Stock Additional paid-in capital Contract with Customer, Liability, Contract with Customer, Liability, [Text Block] Contract Liabilities Significant Accounting Policies [Text Block] Summary of significant accounting policies Schedule of Cash and Cash Equivalents [Table Text Block] Schedule of Cash and Cash Equivalents Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Number of share options granted Number of Options, Granted during the period Disaggregation of Revenue [Table] Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Schedule of Computation of Net Loss Per Share Increase (decrease) in trade and other payables. Increase (Decrease) In Trade And Other Payables Decrease in trade and other payables Earnings Per Share, Basic Net loss per share basic Earnings Per Share, Basic, Total Loss per share basic Disaggregation of Revenue [Table Text Block] Summary of Disaggregation of Revenue from Contracts with Customers Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax Foreign currency translation adjustments (net of tax) Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Total Foreign exchange differences arising on consolidation of foreign operations (net of tax) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Options outstanding Number of Options, Outstanding at January 1, 2026 Number of Options, Outstanding at June 30, 2026 Liabilities, Current Total current liabilities Total current liabilities Increase (Decrease) in Accounts Receivable Decrease in trade receivables Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Adjustments to reconcile net loss to net cash (used in) provided by operating activities: Equity, Attributable to Parent [Abstract] Shareholders' equity Entity Small Business Retained Earnings (Accumulated Deficit) Accumulated losses Retained Earnings (Accumulated Deficit), Total Accumulated deficit Accumulated deficit Accumulated losses Nature of Operations [Text Block] General Information Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Number of Options, Lapsed or forfeited during the period Sale of stock, price per share Sale of stock, price per share Share-Based Payment Arrangement [Text Block] Equity-Settled Share-Based Compensation Leases [Abstract] Contract with Customer, Liability Contract liabilities, ending Contract liabilities, beginning Upfront cash payment received Total contract liabilities Amendment Flag Product and Service [Domain] Options exercised five. Options Exercised Five [Member] Options exercised at $9.98/ADS or $3.33/ordinary share Entity Address, Postal Zip Code Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Cash outflows from operating activities Cash outflows from operating activities Net cash used in operations Increase (Decrease) in Operating Lease Liability Decrease in operating lease liabilities Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description Common Stock [Member] Ordinary Shares Ordinary share Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Granted during the year Contract with customer, liability additions. Contract with Customer, Liability Additions Additions during period Entity Address, Address Line One Earnings Per Share [Abstract] Supplemental Cash Flow Information [Abstract] Supplemental disclosures of cash flow information: Operating Lease, Right-of-Use Asset Operating lease right-of-use asset Net foreign exchange impacts. Net Foreign Exchange Impacts Net foreign exchange impacts Contract with Customer, Liability revenue unwound Contract with Customer, Liability Revenue unwound Revenue unwound during period Document Type Income Taxes Paid, Net Income Taxes Paid, Net, Total Tax paid Gross Profit Gross profit Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Research and development benefit receivable current. Research And Development Benefit Receivable Current R&D benefit receivable Research and development, current asset Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Entity Central Index Key Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Excluding Exchange Rate Effect, Including Discontinued Operation Increase/(decrease) in cash and cash equivalents Ordinary shares - par value Ordinary shares, par value Shares issued during the year Research and Development, Claim Amount Received Research and development, claim amount received. R&D benefit received Schedule of Stockholders Equity [Table Text Block] Details of Shares Issued Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Options exercised Number of Options, Exercised during the period Options exercised in the period, Shares GERMANY Germany Current Fiscal Year End Date Supplemental balance sheet information related to operating lease. Supplemental Balance Sheet Information Related to Operating Lease [Table Text Block] Summary of Supplemental Balance Sheet Information Related to Operating Lease Document Quarterly Report Entity Address, State or Province Comprehensive Income (Loss), Net of Tax, Attributable to Parent Total comprehensive loss for the period Summary of significant accounting policies. Summary Of Significant Accounting Policies [Line Items] Geographical [Axis] Contract with Customer, Liability [Abstract] Contract liabilities: Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Schedule of Deferred Tax Assets Stock option, exercise price. Stock Option Exercise Price Exercise price of stock option Other Comprehensive Income (Loss), Net of Tax [Abstract] Other comprehensive (loss)/income: Contract with customer liability foreign exchange impact. Contract With Customer Liability Foreign Exchange Impact Foreign exchange impact Property, Plant and Equipment [Abstract] Other Assets, Noncurrent Other long-term assets Other long-term assets Number of Authorized Shares Not Disclosed Number of Authorized Shares Not Disclosed Number of authorized shares not disclosed AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Income Options exercised seventeen. Options Exercised Seventeen [Member] Options exercised at $20.41/ADS or $6.80/ordinary share Options exercised ten. Options Exercised Ten [Member] Options exercised at $10.68/ADS or $3.56/ordinary share Options exercised seven. Options Exercised Seven [Member] Options exercised at $7.60/ADS or $2.53/ordinary share American depositary share (ADS). American Depositary Share (ADS) [Member] American Depositary Shares Minimum [Member] Minimum Assets, Current [Abstract] Current assets Segment Reporting [Abstract] Operating lease weighted-average remaining lease term and weighted average discount rate. Operating Lease Weighted Average Remaining Lease Term and Weighted Average Discount Rate [Table Text block] Summary of Weighted-average Remaining Lease Term and Weighted-average Discount rate for Operating Leases Liabilities, Current [Abstract] Current liabilities Restructuring and Related Activities Disclosure [Text Block] Restructuring Charges Related Party Transactions [Abstract] Shares, Outstanding Ending balance, Shares Beginning balance, Shares Number of ADSs in issue Number of equivalent ADSs in issue Accounts Receivable, after Allowance for Credit Loss, Current Trade receivables Accounts Receivable, after Allowance for Credit Loss, Current, Total Other Income Other income, net Commitments and Contingencies Commitments and contingencies (Note 11) Schedule of Goodwill [Table Text Block] Schedule of Change in Carrying Value of Goodwill Revenue from royalties. Revenue From Royalties Royalties Options exercised one. Options Exercised One [Member] Options exercised at $0.20/ADS or $0.07/ordinary share Collaboration agreement with Hansoh. Collaboration Agreement With Hansoh [Member] Collaboration Agreement with Hansoh Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Royalty income. Royalty Income [Member] Royalty Income Royalties Weighted Average Number of Shares Outstanding, Basic Weighted-average shares outstanding basic Weighted Average Number of Shares Outstanding, Basic, Total Document Information [Line Items] Options exercised nine. Options Exercised Nine [Member] Options exercised at $9.98/ADS or $3.33/ordinary share Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Aggregate Intrinsic Value Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Schedule of Reconciliation of Income Tax Credit Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Proceeds from Issuance of Private Placement Gross proceeds from private placement Gross proceeds of offering Subsequent Events [Text Block] Subsequent Events Options exercised fourteen. Options Exercised Fourteen [Member] Options exercised at $15.38/ADS or $5.13/ordinary share Related Party Transactions Disclosure [Text Block] Related Party Transactions APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Recognition of share-based payments APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total Equity, Attributable to Parent Ending balance Beginning balance Value of ADS remained Total shareholders' equity Basis of Accounting, Policy [Policy Text Block] Basis of preparation Statement of Stockholders' Equity [Abstract] Use of Estimates, Policy [Policy Text Block] Use of estimates Gain (Loss), Foreign Currency Transaction, before Tax Gain (Loss), Foreign Currency Transaction, before Tax, Total Net foreign exchange impacts Foreign currency gain/(loss), net UNITED STATES USA Other Assets, Current Other current assets Total other current assets Other Segment Reporting Item Income (loss) Net Other segment reporting item income (loss) net. Other segment items Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration] Cost of sales Cost of Product and Service Sold Cost of Goods and Services Sold, Total Cost of sales Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights Vesting rights Entity Address, City or Town Options exercised in the period Stock Issued During Period Value Share Options Exercised Stock issued during period value share options exercised. Number of Reportable Segments Number of reportable segments Security Exchange Name Commitments Contingencies and Guarantees [Text Block] Capital Commitments and Contingent Liabilities Counterparty Name [Axis] Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Loss before tax Loss before income tax expense Loss before income tax expense Research and development benefit received. Research And Development Benefit Received R&D benefit received General information. General Information [Abstract] Stockholders' Equity Note [Abstract] Statistical Measurement [Domain] Assets, Current Total current assets Document Period End Date Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Number of Options, Exercisable at the period-end Statement of Financial Position [Abstract] Purchase of term deposits. Purchase Of Term Deposits Purchase of term deposits Class of Stock [Axis] Liabilities Total liabilities Total liabilities Weighted Average Number of Shares Outstanding, Diluted Weighted-average shares outstanding diluted Weighted Average Number of Shares Outstanding, Diluted, Total Entity File Number Options exercised eleven. Options Exercised Eleven [Member] Options exercised at $12.81/ADS or $4.27/ordinary share Benefit from R&D credit Gain from research and development credit. Gain From Research And Development Credit Cover [Abstract] Increase (decrease) R&D benefit receivable. Increase (Decrease) In Research And Development Benefit Receivable Decrease in R&D benefit receivable Summary of Valuation Allowance [Table Text Block] Schedule of Movements in Deferred Tax Valuation Allowance Sale of Stock [Domain] Segment Reporting Disclosure [Text Block] Segment Reporting General and Administrative Expense General & administrative expenses General and Administrative Expense, Total General and administrative expenses Maximum Percentage of Commission Payable on Aggregate Gross Proceeds Maximum percentage of commission payable on aggregate gross proceeds. Maximum percentage of commission payable on aggregate gross proceeds Restructuring Charges Restructuring Charges, Total Restructuring charges Restructuring charges New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Pronouncements Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Summarizes of Maturities of Operating Leases Options exercised two. Options Exercised Two [Member] Options exercised at $4.23/ADS or $1.41/ordinary share Contract with Customer, Liability, Current Contract liabilities Current Contract liabilities Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Vesting period for options Depreciation Depreciation expense Depreciation, Total Milestone payments received. Milestone Payments Received Milestone payments received Common Stock, Shares, Outstanding Number of shares in issue Operating Lease, Liability, Current Lease liability - current Operating lease liabilities, current Operating lease liabilities, current Document Transition Report Options exercised six. Options Exercised Six [Member] Options exercised at $7.32/ADS or $2.44/ordinary share Short-Term Investments Short-term investments Short-Term Investments, Total Research and Development Expense Other R&D costs (c) Research and Development Expense, Total Research and development costs Options exercised three. Options Exercised Three [Member] Options exercised at $4.48/ADS or $1.49/ordinary share No Trading Symbol Flag No Trading Symbol Flag Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Schedule of Components of Tax Expense Statement of Cash Flows [Abstract] American Depositary Shares. American Depositary Shares [Member] American Depositary Shares Stock Issued During Period, Value, New Issues Proceeds from shares issued Share-Based Payment Arrangement, Option, Activity [Table Text Block] Schedule of Options Outstanding Details Summary of Options Business Development Contracted development costs Contracted development costs Equity [Text Block] Shareholders' equity Summary Of Significant Accounting Policies [Table] Summary Of Significant Accounting Policies [Table] Earnings Per Share [Text Block] Loss Per Share (Basic and Diluted) Net loss Net loss Net Loss Other Intangible Assets, Net Other intangible assets Other Nonoperating Income Other income, net Total other income Going concern. Going Concern Policy [Policy Text Block] Going concern Restructuring and Related Activities [Abstract] Document Fiscal Year Focus Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Cash flow from investing activities Increase (Decrease) in Other Noncurrent Assets Decrease in other long-term assets Personnel Research And Development Costs. Personnel Research And Development Costs Personnel research and development costs Personnel research and development costs Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block] Schedule of Contract Liabilities Restructuring Cost and Reserve [Line Items] Number of ordinary shares for each American depositary share. Number Of Ordinary Shares For Each American Depositary Share Number of ordinary shares per ADS Commitments and Contingencies Disclosure [Abstract] Share-Based Payment Arrangement [Abstract] Sale of Stock [Axis] Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash provided by/(used in) investing activities Private Placement [Member] Private Placement Title of 12(b) Security Schedule of Segment Reporting Information, by Segment [Table] Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted Average Exercise price, Lapsed or forfeited during the year Research collaboration - Mallinckrodt plc. Research Collaboration Mallinckrodt Plc [Member] Research Collaboration - Mallinckrodt plc Document Information [Table] Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Change in operating assets and liabilities: Property, Plant and Equipment [Table Text Block] Schedule of Property, Plant, and Equipment Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price, Outstanding at the beginning of the year Weighted average Exercise price Weighted Average Exercise price, Outstanding at June 30, 2026 Income Tax Disclosure [Abstract] Additional Paid-in Capital [Member] Additional Paid-in Capital UNITED KINGDOM UK Trading Symbol Schedule of Finite-Lived Intangible Assets [Table Text Block] Schedule of Intangible Assets Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Net cash provided by financing activities Cash flow from financing activities Equity Components [Axis] Equity Component [Domain] Goodwill and Intangible Assets Disclosure [Abstract] Increase (Decrease) in Other Current Assets (Increase)/decrease in other current assets Statement of Comprehensive Income [Abstract] Maximum [Member] Maximum Schedule of Stock by Class [Table Text Block] Schedule of Shares Outstanding Statistical Measurement [Axis] Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Weighted Average Exercise price, Exercised during the year Contract with Customer, Liability, Noncurrent Contract liabilities Non-current Contract liabilities Common Stock, Value, Issued Authorized, allotted, called up and fully paid ordinary shares, par value 0.05 Ordinary shares - par value 0.05 per share; 141,739,180 shares issued at June 30, 2026 (December 31, 2025: 141,701,848) Ordinary shares - par value GBP 0.05 per share; 141,739,180 shares issued at June 30, 2026 (December 31, 2025: 141,701,848) Revenue from contract with customer research collaboration. Revenue From Contract With Customer Research Collaboration Research collaboration - total Research collaboration Cash and Cash Equivalents [Abstract] Consolidation, Policy [Policy Text Block] Principles of consolidation Number of ordinary shares denominated in temporary equity. Number of Ordinary Shares Denominated in Temporary Equity Number of ordinary shares in American Depositary Share Benefit from Research and Development Credit [Abstract] Benefit from research and development credit. Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] Schedule of Expected Future Amortization Expense Revenue from Contract with Customer [Text Block] Revenue Entity Registrant Name Options exercised twelve. Options Exercised Twelve [Member] Options exercised at $12.94/ADS or $4.31/ordinary share Subsequent Events [Abstract] Income Tax Expense (Benefit) Taxation Income tax expense Income tax expense Tax expense Income tax expense Proceeds from Issuance of Common Stock Proceeds from issue of ordinary shares Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Entity Common Stock, Shares Outstanding Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated other comprehensive loss Payments to Acquire Property, Plant, and Equipment Payments to Acquire Property, Plant, and Equipment, Total Purchase of property, plant and equipment Research collaboration income. Research Collaboration Income [Member] Research Collaboration Income Research Collaboration Assets Total assets Income Statement [Abstract] Restructuring Cost [Table] Deferred Income Tax Expense (Benefit) Deferred tax expense Total deferred tax Income tax expense Research Collaboration Hansoh [Member] Research Collaboration Hansoh [Member] Research collaboration - Hansoh Sale of Stock, Number of Shares Issued in Transaction Sale of stock, number of shares issued Sales made under agreement Proceeds from shares issued, Shares Shares issued during the year Accounts Payable, Other, Current Trade and other payables Trade and other payables Earnings Per Share, Diluted Net loss per share diluted Earnings Per Share, Diluted, Total Loss per share diluted Schedule of Segment Reporting Information, by Segment [Table Text Block] Summary of Segment Information Capital commitments. Capital commitments Capital commitments Benefit from R&D Credit Benefit from Research and Development Credit Disclosure [Text Block] Benefit from research and development credit disclosure. City Area Code Other Comprehensive Income (Loss), Net of Tax Total other comprehensive (loss)/income for the period Counterparty Name [Domain] Options exercised fifteen. Options Exercised Fifteen [Member] Options exercised at $16.64/ADS or $5.55/ordinary share Segment Reporting Information [Line Items] Jefferies LLC. Jefferies LLC [Member] Jefferies LLC Property, Plant and Equipment, Net Property, plant and equipment Property, plant, and equipment, net Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Cash and cash equivalents, end of period Cash and cash equivalents at start of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Operating loss Operating Income (Loss) Operating loss Goodwill, Foreign Currency Translation, Gain (Loss) Translation adjustment Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block] Summary of Group's Assets and Revenues by Location Retained Earnings [Member] Accumulated Deficit Entity Address, Country Assets, Noncurrent Non-current assets Non-current assets Share-Based Payment Arrangement, Noncash Expense Share-based compensation expense Share-Based Payment Arrangement, Noncash Expense, Total Stock-based payments charge Payments of Stock Issuance Costs Placement agent fees and other expenses Stock issuance costs Options exercised eight. Options Exercised Eight [Member] Options exercised at $8.20/ADS or $2.73/ordinary share Operating Lease, Liability, Noncurrent Lease liability - non-current Operating lease liabilities, long-term Operating lease liabilities Class of Stock [Line Items] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash provided by financing activities Lease, Cost [Table Text Block] Summary of Components of Total Operating Lease Cost Options exercised nineteen. Options Exercised Nineteen [Member] Options exercised at $23.60/ADS or $7.87/ordinary share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of Outstanding Potentially Dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share Entity Interactive Data Current Entity Interactive Data Current Increase (Decrease) in Contract with Customer, Liability Decrease in contract liabilities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Cash flow from operating activities Options exercised eighteen. Options Exercised Eighteen [Member] Options exercised at $22.01/ADS or $7.34/ordinary share Research and Development Tax Credits Amount Research and development tax credits amount. Research and development tax credits Entity Tax Identification Number Revenues [Abstract] Functional and reporting currency. Functional And Reporting Currency Policy [Policy Text Block] Functional and reporting currency Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Effect of exchange rate fluctuations on cash and cash equivalents held Schedule of Stock Options Roll Forward [Table Text Block] Schedule of Options Outstanding Proceeds from Issuance or Sale of Equity Gross proceeds from sale of stock Proceeds from Issuance or Sale of Equity, Total Local Phone Number Accounting Policies [Abstract] Disaggregation of Revenue [Line Items] Revenue from Contract with Customer, Excluding Assessed Tax Revenue Revenue Total revenue from contracts with customers Options exercised four. Options Exercised Four [Member] Options exercised at $7.19/ADS or $2.40/ordinary share Class of Stock [Domain] Cash, Cash Equivalents, and Short-Term Investments Cash and cash equivalents and short-term investments Cash, Cash Equivalents, and Short-Term Investments, Total Stock, Class of Stock [Table] Entity Emerging Growth Company