v3.26.1
Summary of Significant Accounting Policies - Additional Information (Details)
3 Months Ended 6 Months Ended 12 Months Ended
Feb. 05, 2024
USD ($)
OrdinaryShare
$ / shares
shares
Jun. 30, 2026
USD ($)
shares
Mar. 31, 2026
USD ($)
Jun. 30, 2025
USD ($)
Mar. 31, 2025
USD ($)
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2025
USD ($)
Summary Of Significant Accounting Policies [Line Items]                  
Net loss   $ 12,268,000 $ 14,957,000 $ 27,354,000 $ 28,530,000 $ 27,225,000 $ 55,884,000    
Accumulated losses   589,632,000       589,632,000     $ 562,572,000
Cash outflows from operating activities           14,085,000 34,093,000    
Cash and cash equivalents and short-term investments   $ 72,100,000       72,100,000      
American Depositary Shares                  
Summary Of Significant Accounting Policies [Line Items]                  
Gross proceeds from private placement $ 120,000,000                
Open Market Sale Agreement | Jefferies LLC                  
Summary Of Significant Accounting Policies [Line Items]                  
Sale of stock, number of shares issued | shares   0              
Open Market Sale Agreement | American Depositary Shares | Jefferies LLC                  
Summary Of Significant Accounting Policies [Line Items]                  
Gross proceeds from sale of stock               $ 27,700,000  
Placement agent fees and other expenses               900,000  
Private Placement | American Depositary Shares                  
Summary Of Significant Accounting Policies [Line Items]                  
Placement agent fees and other expenses $ 7,700,000                
Sale of stock, number of shares issued | shares 5,714,286                
Number of ordinary shares in American Depositary Share | OrdinaryShare 3                
Sale of stock, price per share | $ / shares $ 21                
Collaboration Agreement with AstraZeneca                  
Summary Of Significant Accounting Policies [Line Items]                  
Milestone payments received           $ 0 $ 0 10,000,000  
Collaboration Agreement with Hansoh                  
Summary Of Significant Accounting Policies [Line Items]                  
Milestone payments received               $ 2,000,000