v3.26.1
Significant Agreements - Additional Information (Details)
 1 Months Ended 3 Months Ended 6 Months Ended
Jun. 29, 2026
USD ($)
Oct. 30, 2024
USD ($)
Jun. 30, 2026
USD ($)
Jan. 31, 2026
USD ($)
Dec. 31, 2025
USD ($)
shares
Oct. 31, 2025
USD ($)
Jun. 30, 2025
USD ($)
Mar. 31, 2025
USD ($)
Nov. 30, 2024
USD ($)
Jul. 31, 2024
USD ($)
Employee
Vote
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Dec. 31, 2026
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Related party accrued expenses and other current liabilities     $ 299,000   $ 4,969,000           $ 299,000   $ 299,000    
Research and development [1]                     50,065,000 $ 22,547,000 86,118,000 $ 42,570,000  
JADE201                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Special development and regulatory milestones payment           $ 22,000,000                  
Fee for nomination of a development candidate           1,500,000                  
Milestone payments                     2,500,000        
Further milestone payment           $ 2,500,000                  
Percentage of royalty reduction           30.00%                  
Terminated period           60 days                  
Milestone payment and recorded the payment as research and development               $ 1,500,000              
Non refundable reservation fee       $ 1,000,000                      
JADE101                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Special development and regulatory milestones payment   $ 22,000,000                          
Fee for nomination of a development candidate   1,500,000                          
Milestone payments                     3,000,000        
Further milestone payment   $ 2,500,000 3,000,000                        
Percentage of royalty reduction   30.00%                          
Terminated period   60 days                          
JADE -301                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Special development and regulatory milestones payment $ 22,000,000                            
Fee for nomination of a development candidate 1,500,000                            
Further milestone payment $ 2,500,000                            
Percentage of royalty reduction 30.00%                            
Terminated period 60 days                            
Paragon | JADE -301                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Additional development costs incurred                     300,000 900,000 1,100,000 1,700,000  
Paragon | JADE -301 | Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Additional development costs incurred                     300,000   1,000,000    
Maximum | JADE201                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Special development and regulatory milestones payment           $ 24,000,000                  
Maximum | JADE101                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Maximum sublicensing fees   $ 20,100,000                          
Maximum | JADE -301                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Maximum sublicensing fees $ 20,100,000                            
Paragon Option Agreement                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Number of employees in joint development committee | Employee                   2          
Number of votes per each employee | Vote                   1          
Option expiration period                   30 days          
Prior written notice period to terminate                   30 days          
Paragon Option Agreement | APRIL                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Additional development costs incurred                       600,000   2,000,000  
Related party accrued expenses and other current liabilities     0               0   0    
Paragon Option Agreement | APRIL | Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Additional development costs incurred                     0 600,000 0 1,900,000  
Paragon Option Agreement | JADE201                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Related party accrued expenses and other current liabilities     0               0   0    
Paragon Option Agreement | JADE201 | Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Additional development costs incurred                       $ 800,000   $ 4,100,000  
Paragon Option Agreement | JADE -301                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Related party accrued expenses and other current liabilities     $ 300,000               $ 300,000   $ 300,000    
Research and development         $ 1,500,000                    
Paragon Option Agreement | Paragon                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Number of employees in joint development committee | Employee                   2          
Paragon Option Agreement | Parade                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Percentage of outstanding capital stock to grant warrants         1.00%                    
Common stock warrant issued | shares         804,519                    
Paragon Option Agreement | Parade | Forecast                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Percentage of outstanding capital stock to grant warrants                             1.00%
Paragon Option Agreement | Achievement of Certain Clinical Development Milestones | Minimum                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Potential milestone payments required to be paid                   $ 10,000,000          
Paragon Option Agreement | Achievement of Certain Clinical Development Milestones | Maximum                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Potential milestone payments required to be paid                   $ 12,000,000          
Cell Line License Agreement                              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                              
Prior written notice period to terminate                   60 days          
Nonrefundable sublicensee fee             $ 100,000                
Non-refundable license fee                 $ 200,000            
[1] Includes related party amounts of $13.0 million and $17.3 million for the three and six months ended June 30, 2026, respectively, and $3.9 million and $11.7 million for the three and six months ended June 30, 2025, respectively (see Note 10).