| Schedule of reconciliation of reported segment net loss to the statement of operations |
| | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | (in thousands) | | 2026 | | 2025 | | 2026 | | 2025 | Research and development | | | | | | | | | | | | | Wages, benefits, and other payroll | | $ | 1,830 | | $ | 1,302 | | $ | 3,288 | | $ | 4,891 | Third-party costs | | | 1,464 | | | 4,154 | | | 3,896 | | | 7,948 | Share-based compensation | | | 49 | | | 248 | | | 191 | | | 492 | Depreciation and amortization | | | — | | | 110 | | | 61 | | | 220 | Total research and development expenses | | | 3,343 | | | 5,814 | | | 7,436 | | | 13,551 | General and administrative | | | | | | | | | | | | | Wages, benefits, and other payroll | | | 2,312 | | | 1,798 | | | 4,203 | | | 4,588 | Third-party costs | | | 4,059 | | | 1,974 | | | 6,474 | | | 4,577 | Share-based compensation | | | 476 | | | 675 | | | 890 | | | 1,289 | Depreciation and amortization | | | 26 | | | 73 | | | 93 | | | 151 | Total general and administrative expenses | | | 6,873 | | | 4,520 | | | 11,660 | | | 10,605 | Impairment of long-lived assets | | | — | | | — | | | — | | | 2,637 | Net gain on lease terminations | | | (1,944) | | | — | | | (2,577) | | | — | Loss from operations | | | (8,272) | | | (10,334) | | | (16,519) | | | (26,793) | Other income (expense), net | | | 451 | | | 949 | | | 1,139 | | | 2,003 | Net loss | | $ | (7,821) | | $ | (9,385) | | $ | (15,380) | | $ | (24,790) |
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