| Schedule of Segment Profit or Loss and Significant Segment Expenses |
Additional information about segment profit or loss and significant segment expenses is as follows: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | | | | | 2026 | | 2025 | | 2026 | | 2025 | | | | | | | Direct R&D program expense | | | | | | | | | | | | | | | | BHV-4157 (Troriluzole) | | $ | 7,704 | | | $ | 14,245 | | | $ | 14,626 | | | $ | 28,033 | | | | | | | | | BHV-2000 (Taldefgrobep Alfa) | | 5,730 | | | 8,045 | | | 15,062 | | | 14,229 | | | | | | | | | BHV-7000 & BHV-7010 (Kv7) | | 13,845 | | | 31,172 | | | 33,578 | | | 62,744 | | | | | | | | BHV-2100 & BHV-2110 (TRPM3 Antagonist) | | (325) | | | 6,845 | | | (530) | | | 23,594 | | | | | | | | | BHV-8000 (TYK2/JAK1) | | 4,142 | | | 21,216 | | | 9,312 | | | 25,589 | | | | | | | | | BHV-1300 (IgG Degrader) | | 9,861 | | | 11,732 | | | 11,003 | | | 20,352 | | | | | | | | | BHV-1310 (IgG Degrader) | | 15 | | | 3,612 | | | (19) | | | 4,686 | | | | | | | | | BHV-1400 (IgA Degrader) | | 11,709 | | | 6,737 | | | 16,846 | | | 11,597 | | | | | | | | | BHV-1600 (β1-AR AAB Degrader) | | (288) | | | 1,806 | | | (99) | | | 4,809 | | | | | | | | BHV-1510 (TROP-2) | | 2,465 | | | 5,384 | | | 6,502 | | | 9,873 | | | | | | | | | BHV-1530 (FGFR3) | | 2,211 | | | 15,393 | | | 3,410 | | | 18,569 | | | | | | | | | Other R&D program expense | | 14 | | | 1,104 | | | 63 | | | 1,615 | | | | | | | | Preclinical research programs R&D Expense | | 7,730 | | | 16,398 | | | 16,279 | | | 41,933 | | | | | | | | R&D personnel expense (excluding share-based compensation)(1) | | 19,421 | | | 20,490 | | | 40,433 | | | 41,627 | | | | | | | | R&D Share-based compensation expense | | 11,983 | | | 13,110 | | | 30,458 | | | 48,344 | | | | | | | | | | | | | | | | | | | | | | | G&A personnel expense (excluding share-based compensation)(1) | | 5,765 | | | 6,004 | | | 11,220 | | | 12,478 | | | | | | | | G&A Share-based compensation expense | | 7,181 | | | 7,702 | | | 16,992 | | | 25,530 | | | | | | | | Other segment items (2) | | 15,736 | | | 20,706 | | | 30,191 | | | 37,660 | | | | | | | | | Non-operating expense (income) | | 12,021 | | | (13,815) | | | 11,853 | | | (14,308) | | | | | | | | Provision for income taxes | | 391 | | | 261 | | | 663 | | | 870 | | | | | | | | Segment net loss | | 137,311 | | | 198,147 | | | 267,843 | | | 419,824 | | | | | | | | | | | | | | | | | | | | | | | | Reconciliation of profit or loss | | | | | | | | | | | | | | | Adjustments and reconciling items | | — | | | — | | | — | | | — | | | | | | | | Consolidated net loss | | $ | 137,311 | | | $ | 198,147 | | | $ | 267,843 | | | $ | 419,824 | | | | | | | |
(1) Personnel expense includes employee payroll, bonus, and employee benefits for medical care, retirement, insurances and other. (2) Other segment items included in Segment net loss include unallocated non-program R&D expense, legal, accounting and other professional service fees, rent and utilities expense, depreciation, and other corporate expenses.
|