v3.26.1
Organization - Additional Information (Details) - USD ($)
$ / shares in Units, shares in Thousands
 1 Months Ended 3 Months Ended 6 Months Ended
Aug. 31, 2026
Apr. 30, 2026
Mar. 31, 2026
Aug. 31, 2025
Feb. 29, 2024
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Dec. 31, 2025
Description Of Organization [Line Items]                    
Common stock, shares issued           299,306   299,306   266,732
Net proceeds from issuance of common stock               $ 89,646,000 $ 254,000  
Accumulated deficit           $ 1,959,861,000   1,959,861,000   $ 1,849,016,000
Cash, cash equivalents and marketable securities           160,500,000   160,500,000    
Success payment liabilities           22,100,000   22,100,000    
Contingent consideration           99,600,000   $ 99,600,000    
Aggregate common stock value sold           $ 89,752,000        
ATM facility                    
Description Of Organization [Line Items]                    
Aggregate common stock value sold             $ 315,000      
Over Allotment Option                    
Description Of Organization [Line Items]                    
Net proceeds from issuance of common stock       $ 80,600,000 $ 180,000,000          
Number of warrants to purchase common stock       1,500 12,700          
Common Stock                    
Description Of Organization [Line Items]                    
Aggregate common stock sold           29,115        
Aggregate common stock value sold           $ 3,000        
Common Stock | ATM facility                    
Description Of Organization [Line Items]                    
Aggregate common stock sold             170      
Common Stock | Underwritten Public Offering                    
Description Of Organization [Line Items]                    
Aggregate common stock sold       24,300 21,800          
Common Stock | Underwriters' Option To Purchase Additional Shares                    
Description Of Organization [Line Items]                    
Aggregate common stock sold       3,400 4,500          
Mayo Clinic Initial Shares | Stock Purchase Agreement                    
Description Of Organization [Line Items]                    
Common stock, shares issued   7,500                
Stock price price per share   $ 3.33                
Net proceeds from issuance of common stock   $ 25,000,000                
Mayo Clinic Election | Stock Purchase Agreement | Forecast                    
Description Of Organization [Line Items]                    
Common stock, shares issued 7,500                  
Stock price price per share $ 3.33                  
Net proceeds from issuance of common stock $ 25,000,000                  
Cowen | ATM facility                    
Description Of Organization [Line Items]                    
Net proceeds from issuance of common stock           $ 68,600,000        
Aggregate common stock sold           21,600        
Cowen | ATM facility | Sales Agreement | Maximum                    
Description Of Organization [Line Items]                    
Aggregate common stock value sold     $ 150,000,000