Commitments and Contingencies (Tables)

6 Months Ended

Jun. 30, 2026

Commitments and Contingencies Disclosure [Abstract]

Schedule of Additional Information Related to Operating Leases

The following table contains additional information related to the Company’s operating leases as of June 30, 2026:


Location		Use		Approximate Square Footage		Commencement Dates		Expiration Dates
Seattle, WA		Office/Laboratory		48,000		March 2019 to September 2020		December 2026 to April 2028
Cambridge, MA		Office/Laboratory		56,000		March 2019 to January 2020		February 2028 to June 2028
South San Francisco, CA		Office/Laboratory		99,000		December 2019 to April 2022		April 2030
Rochester, NY		Office/Laboratory		3,000		January 2022		January 2027
Bothell, WA		Office/Laboratory/Manufacturing		80,000		January 2023		January 2039

Summary of Lease Costs

The following table summarizes the Company’s lease costs:


		Three Months Ended June 30,								Six Months Ended June 30,
		2026				2025				2026				2025
		(in thousands)
Operating lease cost		$	4,462			$	11,384			$	8,914			$	16,080
Short-term lease cost			624				918				1,339				1,981
Variable lease cost			2,227				2,169				4,376				3,995
Total lease cost		$	7,313			$	14,471			$	14,629			$	22,056

Reconciliation of Undiscounted Operating Lease Cash Flows by Fiscal Year to Present Value of Operating Lease Liabilities

The following table reconciles the Company’s undiscounted operating lease cash flows by fiscal year to the present value of the operating lease liabilities as of June 30, 2026 (in thousands):


2026 (remaining 6 months)		$	11,274
2027			20,604
2028			15,949
2029			14,071
2030			7,758
2031 and thereafter			40,943
Total undiscounted lease payments			110,599
Less: imputed interest			(36,860	)
Present value of operating lease liabilities			73,739
Less: current portion of operating lease liabilities		$	(14,507	)
Operating lease liabilities, net of current portion		$	59,232