Commitments and Contingencies - Additional Information (Detail) $ in Thousands |
1 Months Ended | 6 Months Ended | |||
|---|---|---|---|---|---|
|
Sep. 05, 2025
USD ($)
ft²
$ / ft²
|
Jul. 30, 2020
USD ($)
|
Jun. 30, 2026
USD ($)
|
Dec. 31, 2025
USD ($)
|
Jun. 30, 2022
USD ($)
|
|
| Commitments And Contingencies Disclosure [Line Items] | |||||
| Operating lease, initial right-of-use asset | $ 22,596 | $ 18,078 | |||
| Waltham Lease [Member] | |||||
| Commitments And Contingencies Disclosure [Line Items] | |||||
| Square feet of office space | ft² | 31,518 | ||||
| Lease commencement date | May 01, 2026 | ||||
| Lease term of contract | 7 years 6 months | ||||
| Extended lease term of contract | 5 years | ||||
| Period by which base rent obligation paid after the commencement date | 5 months | ||||
| Initial base rent per square foot per year | $ / ft² | 32 | ||||
| Rent annual increase per square foot | $ / ft² | 1 | ||||
| Operating lease, initial right-of-use asset | $ 5,700 | ||||
| Security deposit amount | $ 300 | ||||
| Plexxikon License Agreement [Member] | |||||
| Commitments And Contingencies Disclosure [Line Items] | |||||
| Clinical milestone achieved, triggering payment | $ 2,500 | ||||
| Milestone payments payable upon achievement regulatory milestones | 5,000 | ||||
| License agreement expiration terms | The License Agreement will expire on a country-by-country and licensed product-by-licensed product basis until the later of the last to expire of the patents covering such licensed products or services or the 10-year anniversary of the date of first commercial sale of the licensed product in such country. The Company may terminate the License Agreement within 30 days after written notice in the event of a material breach. The Company may also terminate the agreement upon written notice in the event of the Company’s bankruptcy, liquidation or insolvency. In addition, the Company has the right to terminate this agreement in its entirety at will upon 90 days’ advance written notice to Plexxikon. | ||||
| Milestone payments payable as a result of progression of on-going clinical studies | $ 15,000 | ||||
| Maximum [Member] | Plexxikon License Agreement [Member] | |||||
| Commitments And Contingencies Disclosure [Line Items] | |||||
| Aggregate payments received upon satisfaction of clinical milestones | $ 7,500 | ||||
| Aggregate payments received | $ 25,000 |