Revenue - Summary of Sales by Product Categories (Detail) - Product - Sales - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
Disaggregation of Revenue [Line Items]
Total Product Revenue	$ 29,105	$ 29,734	$ 53,535	$ 60,305
Total Product Revenue, Percentage	100.00%	100.00%	100.00%	100.00%
ETUARY
Disaggregation of Revenue [Line Items]
Total Product Revenue	$ 27,959	$ 23,516	$ 48,926	$ 45,223
Total Product Revenue, Percentage	96.10%	79.10%	91.40%	75.00%
Contiva
Disaggregation of Revenue [Line Items]
Total Product Revenue	$ 883	$ 1,500	$ 1,732	$ 1,779
Total Product Revenue, Percentage	3.00%	5.00%	3.20%	3.00%
Etorel
Disaggregation of Revenue [Line Items]
Total Product Revenue	$ 255	$ 1,597	$ 927	$ 1,596
Total Product Revenue, Percentage	0.90%	5.40%	1.70%	2.60%
Other Products
Disaggregation of Revenue [Line Items]
Total Product Revenue		$ 158	$ 31	$ 231
Total Product Revenue, Percentage	0.00%	0.50%	0.10%	0.40%
Collaborations
Disaggregation of Revenue [Line Items]
Total Product Revenue	$ 8	$ 2,963	$ 1,919	$ 11,476
Total Product Revenue, Percentage	0.00%	10.00%	3.60%	19.00%