v3.26.1
Segment Reporting - Schedule of Reconciliation of Segment Profits to Income before Taxes (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Segment Reporting [Line Items]        
Sales $ 16,607 $ 15,806 $ 32,893 $ 31,335
Less segment costs:        
Cost of sales 4,395 3,557 8,590 6,976
Selling, general and administrative 2,904 2,649 5,604 5,202
Research and development (9,741) (4,048) (22,333) (7,669)
Other segment items (99) 7 (237) 43
Pretax loss (683) 4,999 (4,217) 10,902
Other profits (683) 4,999 (4,217) 10,902
Unallocated:        
Interest income 35 69 70 178
Interest expense (525) (305) (1,004) (618)
Amortization     (1,915) (1,198)
Depreciation     (1,180) (1,020)
Research and development (9,741) (4,048) (22,333) (7,669)
Restructuring costs (151) (560) (346) (629)
Total segment profits        
Segment Reporting [Line Items]        
Sales 16,535 15,696 32,675 30,922
Less segment costs:        
Pretax loss 12,248 11,696 24,510 23,199
Other profits 12,248 11,696 24,510 23,199
Unallocated:        
Depreciation (85) (63) (176) (124)
Total segment profits | Pharma- ceutical        
Segment Reporting [Line Items]        
Sales 14,760 14,050 29,109 27,688
Less segment costs:        
Cost of sales 1,731 1,601 3,284 3,174
Selling, general and administrative 1,437 1,367 2,750 2,611
Research and development 0 0 0 0
Other segment items (20) (21) (76) (70)
Pretax loss 11,612 11,103 23,151 21,973
Other profits 11,612 11,103 23,151 21,973
Unallocated:        
Depreciation (1) (1) (2) (2)
Research and development 0 0 0 0
Total segment profits | Animal Health        
Segment Reporting [Line Items]        
Sales 1,775 1,646 3,566 3,234
Less segment costs:        
Cost of sales 715 659 1,389 1,258
Selling, general and administrative 304 284 585 544
Research and development (120) (110) (232) (205)
Other segment items 0 0 1 1
Pretax loss 636 593 1,359 1,226
Other profits 636 593 1,359 1,226
Unallocated:        
Depreciation (84) (62) (174) (122)
Research and development (120) (110) (232) (205)
Other profits        
Segment Reporting [Line Items]        
Sales 72 110 218 413
Less segment costs:        
Research and development (9,577) (3,844) (21,981) (7,321)
Pretax loss 30 30 136 231
Other profits 30 30 136 231
Unallocated:        
Interest income 35 69 70 178
Interest expense (525) (305) (1,004) (618)
Amortization (984) (601) (1,915) (1,198)
Depreciation (513) (455) (1,004) (896)
Research and development (9,577) (3,844) (21,981) (7,321)
Restructuring costs (151) (560) (346) (629)
Other unallocated, net $ (1,246) $ (1,031) $ (2,683) $ (2,044)