v3.26.1
Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details)
3 Months Ended 6 Months Ended
Jun. 30, 2026
USD ($)
position
shares
Jun. 30, 2025
USD ($)
shares
Jun. 30, 2026
USD ($)
segment
position
shares
Jun. 30, 2025
USD ($)
shares
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Jan. 31, 2010
cvr
Property, Plant, and Equipment              
Number of operating segments | segment     1        
Number of reportable segments | segment     1        
Number of positions in an unrealized loss position | position 103   103        
Unrealized losses $ 700,000   $ 700,000        
Credit losses related to available-for-sale debt securities 0 $ 0 0 $ 0      
Increase (decrease) in allowance for credit losses 200,000 100,000 30,000.00 400,000      
Inventory write-down 0 0 0 0      
Inventory 10,263,000   10,263,000   $ 9,126,000    
Fair value adjustments to partner program derivatives 0 $ (1,276,000) 0 (833,000)      
Equity method investments $ 42,390,000   42,390,000   $ 46,500,000    
Unrealized gain (loss) on equity method investments     $ (754,000) $ (71,000)      
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares 5,717,000 1,360,000 4,158,000 1,062,000      
Options, Restricted Stock Awards And 2030 Convertible Senior Notes              
Property, Plant, and Equipment              
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares       700,000      
Performance Shares              
Property, Plant, and Equipment              
Performance period for awards (in years) 3 years            
Performance Shares | Minimum              
Property, Plant, and Equipment              
Payout range (as a percent) 0.00%            
Performance Shares | Maximum              
Property, Plant, and Equipment              
Payout range (as a percent) 200.00%            
Metabasis Therapeutics              
Property, Plant, and Equipment              
Number of contingent value rights issued | cvr             4
Equity securities in Primrose Bio              
Property, Plant, and Equipment              
Impairment of equity method investment $ 0 $ 0 $ 0 $ 0      
Equity method investments           $ 0  
Investment owned, net assets, percentage 31.50%   31.50%   31.50%    
Pelthos Series A convertible preferred shares              
Property, Plant, and Equipment              
Unrealized gain (loss) on equity method investments $ 24,900,000 0 $ (9,400,000) 0      
Agenus Warrant And Castle Creek Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives   1,200,000   600,000      
Agenus Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives   1,400,000   900,000      
Castle Creek Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives   (200,000)   (300,000)      
Agenus Bot/Bal              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives   (800,000)   (500,000)      
Equity securities in Primrose Bio              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives   (700,000)   (600,000)      
Castle Creek Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives   $ 300,000   $ 300,000      
Warrants And Option              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives 1,400,000   500,000        
Orchestra Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives 300,000   300,000        
LeonaBio Warrants (noncurrent)              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives (600,000)   400,000        
Agenus Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives (200,000)   (100,000)        
Arecor Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives (100,000)   (200,000)        
Pelthos Conversion Option              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives 1,900,000   (100,000)        
Castle Creek Warrant              
Property, Plant, and Equipment              
Fair value adjustments to partner program derivatives 40,000.00   300,000        
Captisol              
Property, Plant, and Equipment              
Inventory $ 1,600,000   $ 1,600,000   $ 2,100,000    
Equity securities in Primrose Bio              
Property, Plant, and Equipment              
Percentage of milestones (as a percent) 50.00%   50.00%