v3.26.1
Note 5 - Significant Agreements and Contracts (Details Textual) - USD ($)
 1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Aug. 31, 2014
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Aug. 31, 2024
Jan. 31, 2023
Research and Development Expense   $ 4,321,772 $ 5,108,625 $ 9,457,191 $ 9,946,423          
Government Assistance, Asset   21,300,000   21,300,000            
Revenues   0 1,757,724 0 3,675,215          
Vertex Option and License Agreement [Member]                    
Research and Development Expense $ 100,000                  
Contractual Obligation $ 117,000,000                  
Agreement, Milestone, Period for Net Sales 12 months                  
Agreement, Maximum Deduction Percentage of Fees and Payments 50.00%                  
Payments for License Agreement $ 100,000     0 0          
National Institute of Aging Grant [Member]                    
Government Assistance, Asset                 $ 300,000 $ 21,000,000
Government Assistance, Income, Increase (Decrease)           $ 6,200,000 $ 8,400,000 $ 6,700,000    
Revenues   0 $ 1,800,000 0 $ 3,700,000          
Proceeds From Grants       20,900,000            
Grant Funding Remaining   0   0            
Deferred Revenue, Current   $ 0   0   $ 400,000        
Grant Funding Forfeited       $ 200,000