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Related Party Transactions - Additional Information (Details) - USD ($)		3 Months Ended		6 Months Ended
	Jan. 23, 2026	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025	Dec. 31, 2025	May 06, 2024
Related Party Transaction [Line Items]
Research and development		$ 15,964,000	$ 7,873,000	$ 27,139,000	$ 15,326,000
Related party \| Support clinical trials \| ICON plc
Related Party Transaction [Line Items]
Research and development		$ 118,000	$ 137,000
Angel Pharmaceuticals, Ltd
Related Party Transaction [Line Items]
Equity ownership interest	49.00%	48.60%		48.60%		49.70%	49.00%
Follow-on Public Offering
Related Party Transaction [Line Items]
Common shares issued in transaction	9,085,778
Share price of stock issued	$ 22.15
Follow-on Public Offering \| Related party \| Puissance Capital Management
Related Party Transaction [Line Items]
Common shares issued in transaction	30,000
Share price of stock issued	$ 22.15