0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Consolidated Statements of Operations and Comprehensive Income (Loss) link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Consolidated Statements of Operations and Comprehensive Loss - Alternative Calculation link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Consolidated Statements of Changes in Stockholders’ Deficit link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Description of the Business link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Goodwill and Indefinite-Lived Intangible Assets link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Net Income (Loss) Per Share Allocable to Common Stockholders link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Property and Equipment link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Accrued Expenses link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Debt link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Equity link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Stock Incentive Plans link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Revenue Arrangements link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Collaboration and License Agreements link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952172 - Disclosure - Segment Reporting link:presentationLink link:calculationLink link:definitionLink 9952173 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Net Income (Loss) Per Share Allocable to Common Stockholders (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Property and Equipment (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Accrued Expenses (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Debt (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Equity (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Stock Incentive Plans (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Segment Reporting (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Description of the Business (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Goodwill and Indefinite-Lived Intangible Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Net Income (Loss) Per Share Allocable to Common Stockholders - Schedule of Computation of Basic and Diluted Net Income (Loss) Per Share Allocable to Common Stockholders (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Net Income (Loss) Per Share Allocable to Common Stockholders - Schedule of Potential Dilutive Shares of Common Stock Excluded from the Computation of the Diluted Net Income (Loss) Per Share Allocable to Common Stockholders (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Fair Value Measurements - Schedule of Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Fair Value Measurements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Fair Value Measurements - Schedule of Cash, Cash Equivalents, and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Fair Value Measurements - Schedule of Fair Value Measurement Inputs and Valuation Techniques (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Fair Value Measurements - Schedule of Roll-Forward of Fair Value (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Fair Value Measurements - Schedule of Fair Value Measurement Inputs and Valuation Techniques for CVR Liability (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Property and Equipment - Schedule of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Property and Equipment - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Accrued Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Leases - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Leases - Schedule of Components of Lease Costs (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Leases - Schedule of Maturity of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Leases - Schedule of Maturity of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Leases - Schedule of Other Information Related to Operating Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Debt - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Debt - Schedule of Outstanding Balance (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Debt - Schedule of Interest Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Debt - Schedule of Future Minimum Payments on the Term Loans (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Equity - “At the Market” Sales Agreement - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Equity - Warrants - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Equity - Schedule of Warranty Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Equity - Preferred Stock - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Equity - Schedule of Reserved Shares of Common Stock for Future Issuance (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Stock Incentive Plans - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Stock Incentive Plans - Schedule of Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Stock Incentive Plans - Schedule of Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Stock Incentive Plans - Schedule of Weighted Average Assumptions Used (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Stock Incentive Plans - Schedule of Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Stock Incentive Plans - Schedule of Restricted Stock Units Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Revenue Arrangements (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Collaboration and License Agreements - WestGene Biopharma Co., Ltd. - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Collaboration and License Agreements - Biogen M.A., Inc. - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Collaboration and License Agreements - National Cancer Institute of the National Institutes of Health - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Collaboration and License Agreements - Shenyang Sunshine Pharmaceutical Co., Ltd - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Segment Reporting - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955558 - Disclosure - Segment Reporting - Schedule of Segment Reporting Information, by Segment (Details) link:presentationLink link:calculationLink link:definitionLink