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Revenue - Allocation of Performance Obligation (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
Collaboration License And Funding Arrangements [Line Items]
Revenue from external customers	$ 8,806	$ 1,973	$ 11,514	$ 30,780
Norgine Agreement
Collaboration License And Funding Arrangements [Line Items]
Remaining performance obligation	35,534		35,534
Revenue from collaborative arrangement, excluding revenue from contract with customer			5,509	28,094
Norgine Agreement, License
Collaboration License And Funding Arrangements [Line Items]
Remaining performance obligation	33,096		33,096
Revenue from collaborative arrangement, excluding revenue from contract with customer			5,457	27,639
Norgine Agreement, R&D - WHIM
Collaboration License And Funding Arrangements [Line Items]
Remaining performance obligation	373		373
Revenue from collaborative arrangement, excluding revenue from contract with customer			5	25
Norgine Agreement, R&D - CN
Collaboration License And Funding Arrangements [Line Items]
Remaining performance obligation	$ 2,065		2,065
Revenue from collaborative arrangement, excluding revenue from contract with customer			47	430
Norgine Agreement, Drug Product Supply
Collaboration License And Funding Arrangements [Line Items]
Revenue from collaborative arrangement, excluding revenue from contract with customer			1,163	0
Norgine Agreement License and Other Revenue
Collaboration License And Funding Arrangements [Line Items]
Revenue from collaborative arrangement, excluding revenue from contract with customer			$ 6,672	$ 28,094