Description of Business and Summary of Significant Accounting Policies (Tables)
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6 Months Ended |
Jun. 30, 2026 |
| Accounting Policies [Abstract] |
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| Schedule of Restricted Cash |
Restricted Cash | | | | | | | | | | | | | (in thousands) | As of June 30, 2026 | | As of December 31, 2025 | | Letter of credit security: Vienna Austria lease | $ | — | | | $ | 224 | | | Letter of credit security: Boston lease | 579 | | | 579 | | | Letter of credit security: Watertown lease | 95 | | | — | | | Total restricted cash | $ | 674 | | | $ | 803 | | | | | | | | | |
In connection with the Company’s lease agreements for its facilities in Boston and Watertown, Massachusetts, the Company maintains letters of credit, which are secured by restricted cash, for the benefit of the respective landlords. As of December 31, 2025, restricted cash related to the Company’s former Vienna, Austria lease, which the Company terminated effective November 30, 2025, was included in other current assets and was subsequently converted to unrestricted cash during the six months ended June 30, 2026. Restricted cash related to the Boston and Watertown lease are included in other current assets and other assets, respectively.
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| Schedule of Cash, Cash Equivalents, and Restricted Cash |
| | | | | | | | | | | | | | | | | (in thousands) | June 30, 2026 | | December 31, 2025 | | | | | | Cash and cash equivalents | $ | 195,095 | | | $ | 217,049 | | | | | | | Restricted cash, current (included within prepaid expenses and other current assets) | 579 | | | 803 | | | | | | | Restricted cash (included in other assets) | 95 | | | — | | | | | | | Total cash, cash equivalents and restricted cash | $ | 195,769 | | | $ | 217,852 | | | | | |
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| Schedule of Assets Measured at Fair Value |
| | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of June 30, 2026 Using: | | (in thousands) | Level 1 | | Level 2 | | Level 3 | | Total | | | | | | | | | | Cash equivalents—money market funds | $ | 191,613 | | | $ | — | | | $ | — | | | $ | 191,613 | | | Marketable securities—federal government agency notes | — | | | 12,874 | | | — | | | 12,874 | | | $ | 191,613 | | | $ | 12,874 | | | $ | — | | | $ | 204,487 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of December 31, 2025 Using: | | (in thousands) | Level 1 | | Level 2 | | Level 3 | | Total | | | | | | | | | | Cash equivalents—money market funds | $ | 123,838 | | | $ | — | | | $ | — | | | $ | 123,838 | | | Marketable securities—U.S. Treasury notes, U.S. Treasury bills, and federal government agency notes | — | | | 35,949 | | | — | | | 35,949 | | | $ | 123,838 | | | $ | 35,949 | | | $ | — | | | $ | 159,787 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
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| Schedule of Debt Securities, Available-for-Sale |
The following table provides amortized cost, unrealized gains and losses and the carrying amount of available-for-sale debt marketable securities as of June 30, 2026: | | | | | | | | | | | | | | | | | | | | | | | | | (in thousands) | Amortized Cost | | Gross Unrealized Gains | | Gross Unrealized Losses | | Fair Value | | | | | | | | | | Federal Government Agency securities | 12,878 | | | — | | | 4 | | | 12,874 | | | Total available-for-sale debt securities | $ | 12,878 | | | $ | — | | | $ | 4 | | | $ | 12,874 | |
The following table provides amortized cost, unrealized gains and losses and the carrying amount of available-for-sale debt marketable securities as of December 31, 2025: | | | | | | | | | | | | | | | | | | | | | | | | | (in thousands) | Amortized Cost | | Gross Unrealized Gains | | Gross Unrealized Losses | | Fair Value | | U.S. Treasury securities | $ | 7,959 | | | $ | 3 | | | $ | — | | | $ | 7,962 | | | Federal Government Agency securities | 27,980 | | | 11 | | | 4 | | | 27,987 | | | Total available-for-sale debt securities | $ | 35,939 | | | $ | 14 | | | $ | 4 | | | $ | 35,949 | |
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| Schedule of Liabilities Measured at Fair Value |
Liabilities Measured at Fair Value The following tables present information about the Company’s financial liabilities measured at fair value on a recurring basis and indicate the level of the fair value hierarchy used to determine such fair values: | | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of June 30, 2026 Using: | | (in thousands) | Level 1 | | Level 2 | | Level 3 | | Total | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Liabilities: | | | | | | | | | Embedded derivative liability | $ | — | | | $ | — | | | $ | 10 | | | $ | 10 | | | | | | | | | | | Class C warrant liability | — | | | — | | | 369 | | | 369 | | | $ | — | | | $ | — | | | $ | 379 | | | $ | 379 | |
| | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of December 31, 2025 Using: | | (in thousands) | Level 1 | | Level 2 | | Level 3 | | Total | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Liabilities: | | | | | | | | | Embedded derivative liability | $ | — | | | $ | — | | | $ | 10 | | | $ | 10 | | | | | | | | | | | Class C warrant liability | — | | | — | | | 977 | | | 977 | | | $ | — | | | $ | — | | | $ | 987 | | | $ | 987 | |
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| Summary of Aggregate Fair Values of Warrant Liability and Derivative Liability |
The following table provides a roll-forward for the six months ended June 30, 2026 of the aggregate fair values of financial instruments for which fair values are determined using Level 3 inputs: | | | | | | | | | | | | | | | | | | | | | | | (in thousands) | Embedded Derivative Liability | | | | Class C Warrant Liability | | Total | | | | Balance as of December 31, 2025 | $ | 10 | | | | | $ | 977 | | | $ | 987 | | | | | | | | | | | | | | | | | | | | | | | | | Change in fair value | — | | | | | (608) | | | (608) | | | | | | | | | | | | | | Balance as of June 30, 2026 | $ | 10 | | | | | $ | 369 | | | $ | 379 | | | |
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| Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions |
The Company calculated the fair value of the Class C Warrants using the Black-Scholes option pricing model, with the following inputs: | | | | | | | | | | | | | | | | | June 30, 2026 | | December 31, 2025 | | Common stock price | | $4.67 | | $4.00 | | Risk-free interest rate | | 4.0 | % | | 3.5 | % | | Expected term (in years) | | 1.4 | | 1.9 | | Expected volatility | | 114.2 | % | | 136.0 | % | | Expected dividend yield | | — | % | | — | % | | | | | |
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| Summary of Stock-Based Compensation Expense Classification |
Stock-based compensation expense was classified in the condensed consolidated statements of operations and comprehensive loss as follows: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | | (in thousands) | 2026 | | 2025 | | 2026 | | 2025 | | | | | | Research and development expense | $ | 484 | | | $ | 340 | | | $ | 1,199 | | | $ | 599 | | | | | | | General and administrative expense | 2,602 | | | 408 | | | 4,300 | | | 668 | | | | | | | Total stock-based compensation | $ | 3,086 | | | $ | 748 | | | $ | 5,499 | | | $ | 1,267 | | | | | |
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| Summary of Basic and Diluted Net Loss per Share Attributable to Common Stockholders |
Basic and diluted net loss per share was calculated as follows: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | | (in thousands, except share and per share data) | 2026 | | 2025 | | 2026 | | 2025 | | | | | | Numerator: | | | | | | | | | | | | Net loss | $ | (16,157) | | | $ | (25,741) | | | $ | (36,398) | | | $ | (25,459) | | | | | | | Denominator: | | | | | | | | | | | | Weighted average shares outstanding—basic and diluted | 126,344,020 | | | 7,412,990 | | | 126,316,523 | | | 7,095,846 | | | | | | Net loss per share— basic and diluted | $ | (0.13) | | | $ | (3.47) | | | $ | (0.29) | | | $ | (3.59) | | | | | |
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| Schedule of Anti-dilutive Securities Excluded from Computation of Diluted Net Loss per Share Attributable to Common Stockholders |
The Company excluded the following potential shares of common stock from the computation of diluted net loss per share for the periods indicated because including them would have had an anti-dilutive effect: | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | (in thousands) | 2026 | | 2025 | | 2026 | | 2025 | | | Options to purchase shares of common stock | 15,333 | | | 308 | | | 15,333 | | | 308 | | | | Unvested restricted stock units | 714 | | | 333 | | | 714 | | | 333 | | | Warrants to purchase shares of common stock (excluding prefunded warrants, which are included in basic shares outstanding) | 2,546 | | | 2,546 | | | 2,546 | | | 2,546 | | | | 18,593 | | | 3,187 | | | 18,593 | | | 3,187 | | |
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