Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] 2012 Long Term Incentive Plan 2012 Long Term Incentive Plan [Member] Amended and Restated 2012 Long Term Incentive Plan [Member] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Share Purchase Agreement [Table] Share Purchase Agreement Trading Arrangement: Trading Arrangement [Axis] Weighted Average Remaining Contractual Term (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted-Average Remaining Contractual Term Maximum Maximum [Member] Statistical Measurement [Domain] Statistical Measurement [Domain] Title of 12(b) Security Title of 12(b) Security Subsequent Event Subsequent Event [Member] Document Fiscal Year Focus Document Fiscal Year Focus Collaboration Agreement, Potential Commercial Sale Milestone Payments Collaboration Agreement, Potential Commercial Milestone Payments Collaboration Agreement, Potential Commercial Milestone Payments Per Program Collaboration Agreement, Potential Commercial Milestone Payments Per Program Collaboration Program, Global, tau/ BMS-986446 Collaboration Program, Global, tau/ BMS-986446 [Member] Collaboration Program, Global, tau/ BMS-986446 Adjustment to Compensation, Amount Adjustment to Compensation Amount Accrued research and development Accrued Research And Development Current Accrued Research And Development Current Number of Units Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] December 2021 At-The-Market Offering December 2021 At-The-Market Offering [Member] December 2021 At-The-Market Offering[Member] Lessee, Operating Lease, Liability, Lease Not Yet Commenced Lessee, Operating Lease, Liability, Lease Not Yet Commenced Lessee, Operating Lease, Liability, Lease Not Yet Commenced 2018 Long Term Incentive Plan Amended and Restated 2018 Long Term Incentive Plan [Member] Amended and Restated 2018 Long Term Incentive Plan [Member] MARCH 2021 PUBLIC OFFERING [Table] UNDERWRITTEN PUBLIC OFFERING [Table] UNDERWRITTEN PUBLIC OFFERING Ordinary shares, $0.01 par value: Authorized shares — 100,000,000 at June 30, 2026 and December 31, 2025 and Issued and outstanding shares — 51,744,327 and 53,832,982 at June 30, 2026 and December 31, 2025, respectively Common Stock, Value, Issued 2027 Lessee, Operating Lease, Liability, to be Paid, Year One Revenue Commissioners, Ireland Revenue Commissioners, Ireland [Member] Payroll and related expenses Employee-related Liabilities, Current Prepaid R&D expenses Prepaid Research and Development Expenses Prepaid Research and Development Expenses Long term deferred revenue, reclassified to current deferred revenue Deferred Revenue Noncurrent , Reclassified To Deferred Revenue Current, Amount Deferred Revenue Noncurrent , Reclassified To Deferred Revenue Current, Amount Other Other Prepaid Expense, Current Restatement Determination Date Restatement Determination Date Valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Collaboration Agreement, Exercise fee per Program Collaboration Agreement, Exercise Fee (US Rights) per Program Collaboration Agreement, Exercise Fee (US Rights) per Program Issuance of ordinary shares upon vesting of restricted stock units (in shares) Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Aggregate intrinsic value, exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Related To Vested Options Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Related To Vested Options Commitment to suppliers included in accrued current liabilities Purchase Commitment, Remaining Minimum Amount Committed Portion of revenue and expenses attributable to company, Percentage Licensing Agreement, Portion of Revenue and Expenses Attributable to Company, Percentage Licensing Agreement, Portion of Revenue and Expenses Attributable to Company, Percentage Weighted average exercise price, vested and expected to vest, ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Schedule of Prepaid and Other Current Assets Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Amendment Flag Amendment Flag BMS (formerly Celgene) Celgene [Member] Celgene [Member] Current liabilities: Liabilities, Current [Abstract] Shares repurchased, price per share (in dollars per share) Shares Acquired, Average Cost Per Share Project [Axis] Project [Axis] Other Other Sundry Liabilities, Current Composition of Certain Balance Sheet Items [Abstract] Composition of Certain Balance Sheet Items [Abstract] Composition of Certain Balance Sheet Items [Abstract] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Standby Letters of Credit Standby Letters of Credit [Member] Loss Contingencies [Table] Loss Contingencies [Table] Collaboration Agreement, Expected Allocation of initial Transaction Price Collaboration Agreement, Expected Allocation of Initial Transaction Price Collaboration Agreement, Expected Allocation of Initial Transaction Price Leases [Abstract] Leases [Abstract] Total non-current liabilities Liabilities, Noncurrent Collaboration revenue Collaboration [Member] Collaboration Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Licensing Agreements Licensing Agreements [Member] Options, granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross PEO Total Compensation Amount PEO Total Compensation Amount Ordinary shares, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Non-current liabilities: Liabilities, Noncurrent [Abstract] Restricted stock unit, beginning balance (in shares) Restricted stock unit, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Share Repurchase Program [Domain] Share Repurchase Program [Domain] Shares used to compute basic net income (loss) per share (in shares) Weighted-average ordinary shares outstanding used in per share calculations- basic (in shares) Weighted Average Number of Shares Outstanding, Basic Euro deferred shares, number of issued shares (in shares) Deferred Shares Shares Issued Deferred Shares Shares Issued Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Collaboration Agreement, Upfront Payment, Payment Term Collaboration Agreement, Upfront Payment, Payment Term Collaboration Agreement, Upfront Payment, Payment Term Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Fees paid in connection with at-the-market offering Fees Paid in connection with the At-the Market offering Fees Paid in connection with the At-the Market offering Total current liabilities Liabilities, Current Lessee, Operating Lease, Liability, to be Paid, Year Four Lessee, Operating Lease, Liability, to be Paid, Year Four South San Francisco, CA South San Francisco, CA [Member] South San Francisco, CA Deferred revenue Increase (Decrease) in Deferred Revenue Concentration Risk [Table] Concentration Risk [Table] Entity Address, City or Town Entity Address, City or Town Restricted stock units granted in period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Research and Development Expense for Major Programs Research And Development Expense By Major Programs [Table Text Block] Research And Development Expense By Major Programs Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Obligations under restructuring plan Restructuring Plan Obligation, Fiscal Year Maturity [Abstract] Restructuring Plan Obligation, Fiscal Year Maturity Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Restricted stock units vested in period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Basis of Preparation and Presentation of Financial Information Basis of Accounting, Policy [Policy Text Block] Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount SharePurchaseTransactionAbstract [Abstract] SharePurchaseTransactionAbstract Sublease income Sublease Income Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Potential Payment for U.S. Commercial Sales Milestones License Agreement, Potential Payment for U.S. Commercial Sales Milestones License Agreement, Potential Payment for U.S. Commercial Sales Milestones Sub-sublease rentals, term of contract Operating Leases, Sublease Rentals, Term of Contract Operating Leases, Sublease Rentals, Term of Contract Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Schedule of Collaborative Arrangements [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Revenue from license and intellectual property License [Member] Other Other Restructuring [Member] UNITED STATES UNITED STATES Reduction in restructuring liability - non-cash Restructuring Liability, Settled without Cash Restructuring Liability, Settled without Cash Subsequent Event Type [Axis] Subsequent Event Type [Axis] Adjustments to Additional Paid in Capital, Other Adjustments to Additional Paid in Capital, Other Thereafter Restructuring Plan Obligation, To Be Paid, After Year Four Restructuring Plan Obligation, To Be Paid, After Year Four AT-THE-MARKET OFFERING [Table] Subsidiary or Equity Method Investee, Sale of Stock, Type [Table] License Agreement [Table] License Agreement [Table] License Agreement [Table] Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Loss on disposal of fixed assets Gain (Loss) on Disposition of Property Plant Equipment Use of Estimates Use of Estimates, Policy [Policy Text Block] Schedule of Other Current Liabilities Schedule of Accrued Liabilities [Table Text Block] 2029 Purchase Obligation, to be Paid, Year Three Schedule of lease liability maturity analysis Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Supplemental disclosures of non-cash investing and financing activities Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Document Period End Date Document Period End Date Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Common stock, cumulative number of shares issued (in shares) Common Stock, Cumulative Number Of Shares Issued Common Stock, Cumulative Number Of Shares Issued Net cash used in investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] 2028 Lessee, Operating Lease, Liability, to be Paid, Year Two Shareholders' Equity Equity [Text Block] Aggregate restructuring charges Restructuring and Related Cost, Cost Incurred to Date Potential payment for achievement of non U.S. commercial sales milestones License Agreement, Potential Payment for Achievement of non U.S. Commercial Sales Milestones License Agreement, Potential Payment for Achievement of non U.S. Commercial Sales Milestones Security Exchange Name Security Exchange Name South San Francisco, California South San Francisco, California [Member] South San Francisco, California 2029 Restructuring Plan Obligation, To Be Paid, Year Three Restructuring Plan Obligation, To Be Paid, Year Three Collaboration Agreement, Allocation of Initial Transaction Price Collaboration Agreement, Allocation of Initial Transaction Price Collaboration Agreement, Allocation of Initial Transaction Price Weighted average exercise price, granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted average remaining contractual term, unvested and expected to vest (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested And Expected To Vest, Weighted Average Remaining Contractual Terms Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested And Expected To Vest, Weighted Average Remaining Contractual Terms Lease Description [Line Items] Lessee, Lease, Description [Line Items] Offering Costs Included In Accounts Payable And Accrued Liabilities Offering Costs Included In Accounts Payable And Accrued Liabilities Offering Costs Included In Accounts Payable And Accrued Liabilities U.S. Federal Income Tax Paid, Federal, after Refund Received Entity Shell Company Entity Shell Company Authorized shares for issuance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Lease liability, current Less: Lease liability, current Operating Lease, Liability, Current Termination Benefits One-time Termination Benefits [Member] BMS (formerly Celgene) BMS (formerly Celgene) [Member] BMS (formerly Celgene) [Member] Segment Information Segment Reporting, Policy [Policy Text Block] Schedule of Property and Equipment Property, Plant, and Equipment [Table Text Block] Net Income (Loss) Per Ordinary Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name License Agreement, Initial Transaction Price Collaboration Agreement, Initial Transaction Price Initial Transaction Price Revenue from Contract with Customers, Initial Transaction Price Earnings Per Share [Abstract] Earnings Per Share [Abstract] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Tenant improvement allowance received Operating Leases, Tenant Improvement Allowance Received Operating Leases, Tenant Improvement Allowance Received Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Revenue from License and Intellectual Property, Share Purchase Agreement Revenue from License and Intellectual Property, Share Purchase Agreement Revenue from License and Intellectual Property, Share Purchase Agreement Share Repurchase Plan Share Repurchase Plan [Member] Share Repurchase Plan 2027 Purchase Obligation, to be Paid, Year One Total liabilities Liabilities Trading Symbol Trading Symbol Geographical [Domain] Geographical [Domain] Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Denominator: Weighted Average Number of Shares Outstanding, Basic [Abstract] Company Selected Measure Name Company Selected Measure Name Increase (reduction) in deferred tax assets Deferred Tax Assets, Period Increase (Decrease) Deferred Tax Assets, Period Increase (Decrease) Sale of Ordinary Shares [Domain] Sale of Stock [Domain] Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Significant accounting policies [line item] Concentration Risk [Line Items] Collaborative Agreement [Abstract] Collaborative Agreement [Abstract] Collaborative Agreement [Abstract] Maximum proceeds from sale of ordinary shares Sale Of Stock, Maximum Aggregate Offering Price, Value Sale Of Stock, Maximum Aggregate Offering Price, Value 2030 Restructuring Plan Obligation, To Be Paid, Year Four Restructuring Plan Obligation, To Be Paid, Year Four 2027 Purchase, Contractual And Restructuring Plan Obligation, Due In Year One Purchase, Contractual And Restructuring Plan Obligation, Due In Year One Credit Facility [Domain] Credit Facility [Domain] Contractual Obligations under License Agreements included in current liabilities Contractual Obligations under License Agreements included in current liabilities Contractual Obligations under License Agreements included in current liabilities Operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Compensation Amount Outstanding Recovery Compensation Amount Individual: Individual [Axis] Shares used to compute diluted net income (loss) per share (in shares) Weighted-average ordinary shares outstanding used in per share calculations- diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Collaboration program, discount rate Collaboration Program, Discount Rate Collaboration Program, Discount Rate 2026 Purchase, Contractual And Restructuring Plan Obligation, Due Remainder Of Fiscal Year Purchase, Contractual And Restructuring Plan Obligation, Due Remainder Of Fiscal Year Entity Emerging Growth Company Entity Emerging Growth Company Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Underlying Security Market Price Change Underlying Security Market Price Change, Percent Deferred income taxes Deferred Income Taxes and Tax Credits Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Less: Present value adjustment (imputed interest) Lessee, Operating Lease, Liability, Undiscounted Excess Amount Leasehold improvements Leasehold Improvements, Gross Money market funds at carrying value Cash Equivalent, Money Market Fund, Carrying Value Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Collaboration Program, Global, PRX019 Collaboration Program, Global, PRX019 [Member] Collaboration Program, Global, PRX019 Line of credit facility Line of Credit Facility, Current Borrowing Capacity Brisbane, California Brisbane, California [Member] Brisbane, California Sub-sublease rentals, percent of rental gain attributable to sublandlord Operating Leases, Sublease Rentals, Percent of Rental Gain Attributable to Sublandlord Operating Leases, Sublease Rentals, Percent of Rental Gain Attributable to Sublandlord Operating lease, payments Operating Lease, Payments Award Timing Predetermined Award Timing Predetermined [Flag] Restricted cash, non-current Restricted Cash, Current Intrinsic value of options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Project [Domain] Project [Domain] Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Share-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Level 1 Fair Value, Inputs, Level 1 [Member] Adjustment for non-cash charges Restructuring Reserve, Settled Without Cash, Period Increase (Decrease) Restructuring Reserve, Settled Without Cash, Period Increase (Decrease) Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Operating lease, future minimum payments due Total Lessee, Operating Lease, Liability, to be Paid Dilutive restricted stock units outstanding (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements Significant Agreements Significant Agreements [Text Block] Significant Agreements [Text Block] Restricted stock units beginning balance (in dollars per share) Restricted stock units ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value All Executive Categories All Executive Categories [Member] Repurchase of ordinary shares Repurchase of ordinary shares Stock Repurchased and Retired During Period, Value Operating lease liabilities Increase (Decrease) in Operating Lease Liability Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Restricted stock unit, unvested and expected to vest (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested And Expected To Vest, Number Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested And Expected To Vest, Number Net reduction in restructuring liability Restructuring Reserve, Period Increase (Decrease) Depreciation expense Depreciation Plan Name [Domain] Plan Name [Domain] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Weighted average exercise price, outstanding beginning balance (in dollars per share) Weighted average exercise price, outstanding ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Operating lease right-of-use assets Operating Lease, Right-of-Use Asset 2030 Contractual Obligation, to be Paid, Year Four Operating lease, Dublin, renewal term of contract (in years) Lessee, Operating Lease, Renewal Term Calculation of Basic and Diluted Net Income (Loss) Per Ordinary Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Restructuring Charges Costs Associated with Exit or Disposal Activities or Restructurings, Policy [Policy Text Block] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Upfront payment pursuant to license agreement Collaboration Revenue, License, Upfront Payment Collaboration Revenue, License, Upfront Payment Minimum Minimum [Member] Line of credit has been used Long-Term Line of Credit Expiration Date Trading Arrangement Expiration Date Collaboration program, Global Exercise Fee Collaboration Program, Option Exercise Fee Collaboration Program, Option Exercise Fee Net decrease in cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Excluding Exchange Rate Effect, Including Discontinued Operation Repurchases of Ordinary Shares Repurchases Of Ordinary Shares, Policy [Policy Text Block] Repurchases Of Ordinary Shares, Policy Area of sub-sublease rental Operating Leases, Sublease Rentals, Area of Sublease Rental Operating Leases, Sublease Rentals, Area of Sublease Rental Collaboration Agreement, Potential Development and Regulatory Milestone Payments Collaboration Agreement, Potential Development and Regulatory Milestone Payments Collaboration Agreement, Potential Development and Regulatory Milestone Payments License agreement, Development services, Payment term License Agreement, Development Services, Payment Term License Agreement, Development Services, Payment Term Income Statement Location [Axis] Location, Statement of Income, Balance [Axis] Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Beginning balance Ending balance Equity, Including Portion Attributable to Noncontrolling Interest Weighted average remaining contractual term, outstanding (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Net Income (Loss) Per Share, Basic and Diluted Income (Loss) Per Share, Basic And Diluted [Abstract] Income (Loss) Per Share, Basic And Diluted Collaboration Program, US License Agreement, Upfront Payment Collaboration Program, US License Agreement, Upfront Payment Collaboration Program, US License Agreement, Upfront Payment Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Proceeds from Issuance of Common Stock Proceeds from Issuance of Common Stock Ordinary shares, number of authorized shares (in shares) Common Stock, Shares Authorized Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Share Subscription Agreement, Number of ordinary shares issued in transaction (in shares) Sale of Stock, Number of Shares Issued in Transaction Tenant improvement allowance Operating Leases, Tenant Improvement Allowance Operating Leases, Tenant Improvement Allowance Exercise Price Award Exercise Price Schedule of Restructuring and Related Costs [Table] Restructuring Cost [Table] Issuance of ordinary shares upon vesting of restricted stock units Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures Investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] PRX012 PRX012 [Member] PRX012 Share repurchase plan, authorized, amount Share Repurchase Program, Authorized, Amount Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Document Quarterly Report Document Quarterly Report Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Share-based Payment [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Accounts Receivable, after Allowance for Credit Loss Accounts Receivable, after Allowance for Credit Loss Collaboration Program, US, Third Program Collaboration Program, US, Third Program [Member] Collaboration Program, US, Third Program Contractual obligations under license agreements Total Contractual Obligation Schedule of Contractual Obligations by Fiscal Year Maturity Contractual Obligation, Fiscal Year Maturity [Table Text Block] Milestone payment received, Clinical milestone Milestone Payment Received, Clinical Milestone Milestone Payment Received, Clinical Milestone Euro deferred shares, €22 nominal value: Authorized shares — 10,000 at June 30, 2026 and December 31, 2025 and Issued and outstanding shares — none at June 30, 2026 and December 31, 2025 Deferred Shares Value Deferred Shares Value Restructuring and Related Costs Restructuring and Related Costs [Table Text Block] Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Equity Component [Domain] Equity Component [Domain] PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount License Agreements License Agreements [Member] License Agreements [Member] Share Subscription Agreement, Consideration received on transaction Sale of Stock, Consideration Received on Transaction Adoption Date Trading Arrangement Adoption Date Counterparty Name [Domain] Counterparty Name [Domain] Total shareholders’ equity Equity, Attributable to Parent Total other income, net Nonoperating Income (Expense) Restructuring Type [Axis] Restructuring Type [Axis] Assets Assets [Abstract] Title Trading Arrangement, Individual Title Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Collaboration Revenue, US Development Services Collaboration Revenue, US Development Services [Member] Collaboration Revenue, US Development Services Accounting Policies [Abstract] Accounting Policies [Abstract] Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Stock issuance costs, cumulative amount Stock Issuance Costs, Cumulative Amount Stock Issuance Costs, Cumulative Amount Total lease liability Total lease liability Operating Lease, Liability Insider Trading Policies and Procedures [Line Items] Options, outstanding beginning balance (in shares) Options, outstanding ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Collaboration Program, US, tau/ BMS-986446 Collaboration Program, US, tau/ BMS-986446 [Member] Collaboration Program, US, tau/ BMS-986446 Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Underwritten Public Offering Underwritten Public Offering [Member] Underwritten Public Offering Prepaid expenses and other current assets Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Private Placement Private Placement [Member] Composition of Certain Balance Sheet Items Supplemental Balance Sheet Disclosures [Text Block] Clinical Product Supply Clinical Product Supply [Member] Clinical Product Supply [Member] Type of Restructuring [Domain] Type of Restructuring [Domain] Potential payment upon achievement of development, regulatory and various first commercial sales milestones License Agreement, Potential Payment Upon Achievement of Development, Regulatory and Various First Commercial Sales Milestones License Agreement, Potential Payment Upon Achievement of Development, Regulatory and Various First Commercial Sales Milestones Purchase Obligation, Due in Fifth Year Purchase Obligation, to be Paid, Year Five Letter of Credit Letter of Credit [Member] Commitment and Contingencies Commitments and Contingencies Disclosure [Text Block] Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Income Taxes [Table] Income Taxes [Table] Income Taxes [Table] Equivalent ordinary shares not included in diluted net income (loss) per share(in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Number of operating segments Number of Operating Segments Restricted Stock Units (RSU) Restricted Stock Units (RSUs) [Member] Ordinary Shares Equivalent Not Included in Diluted Net Income (Loss) Per Ordinary Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Entity Central Index Key Entity Central Index Key Less: accumulated depreciation and amortization Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization All Adjustments to Compensation All Adjustments to Compensation [Member] Equity [Abstract] Equity [Abstract] Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Net cash provided by (used in) operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Income Statement [Abstract] Income Statement [Abstract] Shareholders’ equity: Equity, Attributable to Parent [Abstract] Novo Nordisk Novo Nordisk [Member] Novo Nordisk Software, Purchased Software, Purchased [Member] Document Transition Report Document Transition Report Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Share Repurchase Program [Table] Share Repurchase Program [Table] Operating expenses: Operating Expenses [Abstract] February 2024 Prospectus At-The-Market Offering February 2024 Prospectus At-The-Market Offering [Member] February 2024 Prospectus At-The-Market Offering Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Fair Value of Options Granted Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Deferred revenue, current Deferred Revenue, Current Share-Based Payment, Options, Outstanding [Roll Forward] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Other Commitments [Domain] Other Commitments [Domain] City Area Code City Area Code License agreement, Milestone payments, Payment term (in days) License Agreement, Milestone Payments, Payment Term License Agreement, Milestone Payments, Payment Term Research And Development Expense By Major Programs [Line Items] Research And Development Expense By Major Programs [Line Items] Research And Development Expense By Major Programs Collaboration Program, Global and US, Third Program Collaboration Program, Global and US, Third Program [Member] Collaboration Program, Global and US, Third Program All Individuals All Individuals [Member] Proceeds from issuance of common stock, cumulative gross amount Proceeds from Issuance of Common Stock, Cumulative Gross Amount Proceeds from Issuance of Common Stock, Cumulative Gross Amount Reduction in the carrying amount of right-of-use assets Operating Lease, Right-of-Use Asset, Periodic Reduction US Rights and Global Rights US Rights and Global Rights [Member] US Rights and Global Rights Collaborative Arrangement Collaborative Arrangement [Member] Name Forgone Recovery, Individual Name Sub-sublease rentals, percent annual rent increase Operating Leases, Sublease Rentals, Percent Annual Rent Increase Operating Leases, Sublease Rentals, Percent Annual Rent Increase Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] RSU, Weighted Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Statement [Line Items] Statement [Line Items] Total non-current assets Assets, Noncurrent Total assets Assets Operating Lease Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] RSU, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract] Ordinary shares, reserved for future issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Share-Based Payment Arrangement, Outstanding Award, Activity, Excluding Option Share-Based Payment Arrangement, Outstanding Award, Activity, Excluding Option [Table Text Block] Weighted average grant date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Collaboration Revenue, Development Services for Phase 1 Clinical Trial Collaboration Revenue, Development Services for Phase 1 Clinical Trial [Member] Collaboration Revenue, Development Services for Phase 1 Clinical Trial Summary of Share-Based Compensation Expense Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Share-Based Compensation Share-Based Payment Arrangement [Text Block] Collaboration Revenue, Transaction Price Collaboration Revenue, Transaction Price Collaboration Revenue, Transaction Price 2026 Contractual Obligation, to be Paid, Remainder of Fiscal Year Prepaid and other assets Increase (Decrease) in Other Operating Assets Issuance of ordinary shares (in shares) Stock Issued During Period, Shares, New Issues PEO PEO [Member] Thereafter Contractual Obligation, to be Paid, after Year Five Beginning balance (in shares) Ending balance (in shares) Shares, Outstanding Shares, Outstanding 2028 Contractual Obligation, to be Paid, Year Two Weighted average exercise price, expired (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Repurchase of ordinary shares (in shares) Shares repurchased (in shares) Stock Repurchased and Retired During Period, Shares Cost sharing payments recognized as research and development expense Research And Development Payment To Collaboration Partner Recorded As Research And Development Expense Research And Development Payment To Collaboration Partner Recorded As Research And Development Expense Number of additional shares authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Options, exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period BMS-986446 (PRX005) BMS-986446 (PRX005) [Member] BMS-986446 (PRX005) Restricted stock units grant-date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Subsequent Event Type [Domain] Subsequent Event Type [Domain] Accumulated Deficit Retained Earnings [Member] Lease liability, non-current Operating Lease, Liability, Noncurrent Total operating expenses Operating Expenses Prepaid G&A expenses Prepaid General and Administrative Expense Prepaid General and Administrative Expense Restricted stock units forfeited fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Options, forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Ordinary shares, number of outstanding shares (in shares) Common Stock, Shares, Outstanding Award Timing Disclosures [Line Items] Diluted net income (loss) per ordinary share (in dollars per share) Diluted (in dollars per share) Earnings Per Share, Diluted Entity Current Reporting Status Entity Current Reporting Status Net cash used in financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Total Shareholder Return Amount Total Shareholder Return Amount Allocated consideration to performance obligations Allocated Consideration to Performance Obligations Revenue, Performance Obligation, Allocated Consideration ( Amount of Transaction Price Allocated to each Performance Obligation) Country Region Country Region Research and development Research and Development Expense Adjustments to reconcile net income (loss) to cash provided by (used in) operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Euro deferred shares, number of shares authorized (in shares) Deferred Shares Shares Authorized Deferred Shares Shares Authorized Total Purchase and Contractual Obligations, Fiscal Year Maturity [Abstract] Purchase and Contractual Obligations, Fiscal Year Maturity [Abstract] Long-term Purchase Commitment [Line Items] Long-Term Purchase Commitment [Line Items] Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Total revenue Collaboration revenue Revenue from Contract with Customer, Excluding Assessed Tax Property and equipment, net Property and equipment, net Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Collaboration Program, US Rights Collaboration Program, US Rights [Member] Collaboration Program, US Rights [Member] Price per share at public offering (in dollars per share) Shares Issued, Price Per Share U.S. State and Local Income Tax Paid, State and Local, after Refund Received Contract Termination Costs Contract Termination [Member] Royalty Bearing License Royalty Bearing License [Member] Royalty Bearing License [Member] Stock Issued During Period, Value, Stock Options Exercised Stock Issued During Period, Value, Stock Options Exercised Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Share Repurchase Program [Line Items] Share Repurchase Program [Line Items] Face amount reduction on third anniversary Line of Credit Facility, Face Amount Reduction on Third Anniversary Line of Credit Facility, Face Amount Reduction on Third Anniversary Underlying Securities Award Underlying Securities Amount Schedule of New Accounting Pronouncements and Changes in Accounting Principles Accounting Standards Update and Change in Accounting Principle [Table Text Block] Issuance of ordinary shares, net of issuance costs Stock Issued During Period, Value, New Issues PRX019 PRX019 [Member] PRX019 Weighted average exercise price, forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Collaboration Agreement, Potential Regulatory and Commercial Milestone Payments per Program Collaboration Agreement, Potential Regulatory and Commercial Milestone Payments Per Program Collaboration Agreement, Potential Regulatory and Commercial Milestone Payments Per Program Discount rate, percent Operating Lease, Weighted Average Discount Rate, Percent Collaboration Program, Global Rights Collaboration Program, Global Rights [Member] Collaboration Program, Global Rights [Member] Number of shares available for grant (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant License agreement, Cost allocation, Percentage Licensing Agreement, Cost Allocation, Percentage Licensing Agreement, Cost Allocation, Percentage Face amount reduction on fifth anniversary Line of Credit Facility, Face Amount Reduction on Fifth Anniversary Line of Credit Facility, Face Amount Reduction on Fifth Anniversary Sale of Ordinary Shares [Axis] Sale of Stock [Axis] Share-Based Payment, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Supply Agreement Collaboration Revenue, Supply Agreement [Member] Collaboration Revenue, Supply Agreement Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Other income (expense): Other Nonoperating Income (Expense) [Abstract] All Trading Arrangements All Trading Arrangements [Member] Other Performance Measure, Amount Other Performance Measure, Amount Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Income (loss) from operations Operating Income (Loss) 2030 Purchase Obligation, to be Paid, Year Four Collaboration Agreement, Upfront Payment Collaboration Agreement, Upfront Payment Collaboration Agreement, Upfront Payment Revenue, Remaining performance obligation, Amount Revenue, Remaining Performance Obligation, Amount Total Purchase, Contractual And Restructuring Plan Obligation, Total Purchase, Contractual And Restructuring Plan Obligation, Total Current Fiscal Year End Date Current Fiscal Year End Date License Agreement [Line Items] License Agreement [Line Items] [Line Items] for License Agreement [Table] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Expected cost Restructuring and Related Cost, Expected Cost Research And Development Expense By Major Programs [Table] Research And Development Expense By Major Programs [Table] Research And Development Expense By Major Programs Restructuring Reserve [Roll Forward] Restructuring Reserve [Roll Forward] Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Entity File Number Entity File Number Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Euro deferred shares, nominal value (in euros per share) Deferred Shares Par Value Deferred Shares Par Value Collaboration Agreement, Potential Regulatory Milestone Payments per Program Collaboration Agreement, Potential Regulatory Milestone Payments Per Program Collaboration Agreement, Potential Regulatory Milestone Payments Per Program Thereafter Purchase Obligation, to be Paid, after Year Four Purchase Obligation, to be Paid, after Year Four Summary of Company's Share Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Share-Based Payment, Options, Outstanding, Weighted Average Exercise Price [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Restructuring Share-Based Compensation Restructuring Share-Based Compensation Restructuring Share-Based Compensation Restructuring costs Restructuring Costs Ordinary shares, number of issued shares (in shares) Common Stock, Shares, Issued Measure: Measure [Axis] At-The-Market Offering At-The-Market Offering [Member] At-The-Market Offering 2028 Purchase Obligation, to be Paid, Year Two Stock Issuance Costs Stock Issuance Costs Stock Issuance Costs Stock Issuance Costs Sub-sublease rentals, initial annual base rent Sublease rentals, Annual Base Rent, Initial Amount Operating Leases, Annual Base Rent from Sub-sublease, Initial Amount Equity Components [Axis] Equity Components [Axis] Product and Service [Domain] Product and Service [Domain] Cash (received) paid for income taxes Income Tax Paid, after Refund Received Bristol Myers Squibb Bristol Myers Squibb [Member] Bristol Myers Squibb Restructuring liability Beginning balance Ending balance Restructuring Reserve, Current Entity Interactive Data Current Entity Interactive Data Current Acquisition of property and equipment included in accounts payable and accrued liabilities Noncash or Part Noncash Acquisition, Fixed Assets Acquired Contractual obligations under license agreements included in accrued current liabilities Contractual Obligations under License Agreements included in accrued current liabilities Contractual Obligations under License Agreements included in accrued current liabilities Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Restricted stock units, unvested and expected to vest (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested And Expected To Vest, Weighted Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested And Expected To Vest, Weighted Average Grant Date Fair Value Supply Services Supply Services [Member] Supply Services [Member] Entity Small Business Entity Small Business Potential Payment for US Commercial Sales Milestones License Agreement, Potential Alternative Commercial Sales Milestones License Agreement, Potential Alternative Commercial Sales Milestones Roche Roche [Member] Roche [Member] Lessee, Operating Lease, Liability, to be Paid, Year Three Lessee, Operating Lease, Liability, to be Paid, Year Three Termination Date Trading Arrangement Termination Date Other Commitments [Axis] Other Commitments [Axis] Property, Plant, and Equipment [Line Items] Property, Plant, and Equipment [Line Items] Irish income tax rate, percent Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Interest income Interest Income (Expense), Operating MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Other current liabilities Other current liabilities Other Liabilities, Current Grant period Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Other non-current assets Other Assets, Noncurrent Document Type Document Type Collaboration Program, Global, Third Program Collaboration Program, Global, Third Program [Member] Collaboration Program, Global, Third Program Lease expiration date Lease Expiration Date Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Income Taxes [Line Items] Income Taxes [Line Items] [Line Items] for Income Taxes [Table] Fair Value as of Grant Date Award Grant Date Fair Value Aggregate intrinsic value, unvested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Restructuring liability Increase (Decrease) in Restructuring Reserve Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Arrangement Duration Trading Arrangement Duration Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] 2027 Restructuring Plan Obligation, To Be Paid, Year One Restructuring Plan Obligation, To Be Paid, Year One Purchase Obligations Purchase Obligation, Fiscal Year Maturity [Abstract] Dilutive stock options outstanding (in shares) Incremental Common Shares Attributable to Dilutive Effect of Nonvested Shares with Forfeitable Dividends Local Phone Number Local Phone Number Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Registrant Name Entity Registrant Name Share Subscription Agreement, Premium received on transaction Sale of Stock, Premium Received on Transaction Sale of Stock, Premium Received on Transaction Income (loss) before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Aggregate intrinsic value, vested and expected to vest, ending balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Commitments and contingencies (Note 6) Commitments and Contingencies Purchase and Contractual Obligation, Due in Fifth Year Purchase and Contractual Obligation, Due in Fifth Year Purchase and Contractual Obligation, Due in Fifth Year Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Property and equipment, gross Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Accounts payable, accruals and other liabilities Increase (Decrease) in Accounts Payable and Accrued Liabilities Thereafter Contractual Obligation, to be Paid, after Year Four Contractual Obligation, to be Paid, after Year Four Machinery and Equipment Machinery and Equipment [Member] Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Collaboration Program, US, PRX019 Collaboration Program, US, PRX019 [Member] Collaboration Program, US, PRX019 Executive Category: Executive Category [Axis] Long-term Purchase Commitment [Table] Long-Term Purchase Commitment [Table] Aggregate intrinsic value, unvested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Nonvested And Expected To Vest Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Nonvested And Expected To Vest Vesting period (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Options, expired (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period Counterparty Name [Axis] Counterparty Name [Axis] Liabilities and Shareholders’ Equity Liabilities and Equity [Abstract] Weighted Average Remaining Contractual Term, exercisable (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term 2029 Contractual Obligation, to be Paid, Year Three Award Type [Domain] Award Type [Domain] 2028 Restructuring Plan Obligation, To Be Paid, Year Two Restructuring Plan Obligation, To Be Paid, Year Two Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Ordinary Shares Ordinary Share [Member] Ordinary Share [Member] 2026 (6 months) Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Fair Value Measurements Fair Value Disclosures [Text Block] Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Weighted average remaining contractual term, vested and expected to vest (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted-Average Remaining Contractual Term Operating lease, term of contract (in years) Lessee, Operating Lease, Term of Contract PEO Name PEO Name Geographical [Axis] Geographical [Axis] Restricted cash Restricted Cash Repurchase of ordinary shares Payments for Repurchase of Equity Birtamimab (NEOD001) Birtamimab (NEOD001) [Member] Birtamimab (NEOD001) 2030 Purchase, Contractual And Restructuring Plan Obligation, Due in Fourth Year Purchase, Contractual And Restructuring Plan Obligation, Due in Fourth Year Long-Lived Asset, Class [Axis] Long-Lived Asset, Class [Axis] Receivable from Stock Option Exercises In-Transit Receivable from Stock Option Exercises In-Transit Receivable from Stock Option Exercises In-Transit Concentration of Risks and Other Risks and Uncertainties Concentration Risk, Credit Risk, Policy [Policy Text Block] Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Foreign currency transactions gain (loss) Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Gain (Loss), before Reclassification and Tax Entity Tax Identification Number Entity Tax Identification Number Tax benefit recognized from share-based compensation expense Share-Based Payment Arrangement, Expense, Tax Benefit Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Reduction for cash payments Payments for Restructuring Weighted average exercise price, exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price 2029 Purchase, Contractual And Restructuring Plan Obligation, Due in Third Year Purchase, Contractual And Restructuring Plan Obligation, Due in Third Year Cash, cash equivalents and restricted cash, beginning of the year Cash, cash equivalents and restricted cash, end of the period Total cash, cash equivalents and restricted cash, end of the period Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Operating Leases, Proceeds From Tenant Allowance Operating Leases, Proceeds From Tenant Allowance Operating Leases, Proceeds From Tenant Allowance IRELAND IRELAND Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Professional services Accrued Professional Fees, Current Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Non-NEOs Non-NEOs [Member] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Organization Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Near-term Clinical Milestone Near-term Clinical Milestone Near-term Clinical Milestone Share-based compensation Share-based compensation expense Share-Based Payment Arrangement, Noncash Expense Income Tax Authority, Name [Domain] Income Tax Authority, Name [Domain] Collaboration Program, tau/ BMS-986446 Collaboration Program, US, tau/ BMS-986446 fka PRX005 [Member] Collaboration Program, US, tau/ BMS-986446 fka PRX005 Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property Basic net income (loss) per ordinary share (in dollars per share) Basic (in dollars per share) Earnings Per Share, Basic Deferred Revenue Deferred Revenue Total current assets Assets, Current Statistical Measurement [Axis] Statistical Measurement [Axis] Insider Trading Arrangements [Line Items] Award Type [Axis] Award Type [Axis] 2020 Employment Inducement Incentive Plan 2020 Employment Inducement Incentive Plan [Member] 2020 Employment Inducement Incentive Plan [Member] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Accounts receivable Accounts Receivable, after Allowance for Credit Loss, Current IND and Development Services IND and Development Services [Member] IND and Development Services [Member] Accumulated deficit Retained Earnings (Accumulated Deficit) Unpaid cost of share repurchases Share Repurchase Program, Unpaid Cost Share Repurchase Program, Unpaid Cost Restructuring and Related Activities [Abstract] Restructuring and Related Activities [Abstract] Product and Service [Axis] Product and Service [Axis] Restricted cash, non-current Restricted Cash, Noncurrent Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Stock Option Common Stock [Member] Income Tax Authority, Name [Axis] Income Tax Authority, Name [Axis] Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Operating lease cost Operating Lease, Cost Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Cover [Abstract] Noncash Or Part Noncash, Reclassification Of Prepaid Lease Payments To Right-Of-Use Assets Upon Lease Commencement Noncash Or Part Noncash, Reclassification Of Prepaid Lease Payments To Right-Of-Use Assets Upon Lease Commencement Noncash Or Part Noncash, Reclassification Of Prepaid Lease Payments To Right-Of-Use Assets Upon Lease Commencement Expected dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Collaboration Agreement, Total Transaction Price, PRX019 US Collaboration Agreement, Total Transaction Price, PRX019 US Collaboration Agreement, Total Transaction Price, PRX019 US Fair Value Measurement Inputs and Valuation Techniques [Table] Fair Value Measurement Inputs and Valuation Techniques [Table] Deferred Revenue, Noncurrent Deferred Revenue, Noncurrent Share Purchase Agreement, Potential Payment Upon Achievement of Development and Sales Milestones Share Purchase Agreement, Potential Payment Upon Achievement of Development and Sales Milestones Share Purchase Agreement, Potential Payment Upon Achievement of Development and Sales Milestones Equity Awards Adjustments Equity Awards Adjustments [Member] 2026 Purchase Obligation, to be Paid, Remainder of Fiscal Year Share-Based Payment Arrangement, Estimated Forfeiture Rate Share-Based Payment Arrangement, Estimated Forfeiture Rate Share-Based Payment Arrangement, Estimated Forfeiture Rate Total liabilities and shareholders’ equity Liabilities and Equity Operating Leases, Improvement Allowance Operating Leases, Improvement Allowance Operating Leases, Improvement Allowance Stock options to purchase ordinary shares Option Awards Share-Based Payment Arrangement, Option [Member] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Restructuring charges Restructuring Charges Plan Name [Axis] Plan Name [Axis] Tabular List, Table Tabular List [Table Text Block] Additional paid-in capital Additional Paid in Capital Operating lease (area) Operating Lease (Area) Operating Lease (Area) Foreign currency transaction gain Foreign Currency Transaction Gain, before Tax Other income (expense), net Other Nonoperating Income (Expense) Name Awards Close in Time to MNPI Disclosures, Individual Name Entity Address, Country Entity Address, Country Options, Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Aggregate intrinsic value, outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Restricted stock units forfeited in period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Transition services Transition services Transition services Non-current assets: Assets, Noncurrent [Abstract] General and administrative General and Administrative Expense Long-Lived Asset, Class [Domain] Long-Lived Asset, Class [Domain] Share Subscription Agreement, Price per share (in dollars per share) Sale of Stock, Price Per Share Total obligations under restructuring plan Total Restructuring Plan Obligation Restructuring Plan Obligation Property, Plant, and Equipment [Table] Property, Plant, and Equipment [Table] Adjustment To Additional Paid-In Capital, Adjustment To At-The-Market Offering Adjustment To Additional Paid-In Capital, Adjustment To At-The-Market Offering Adjustment To Additional Paid-In Capital, Adjustment To At-The-Market Offering Adjustment to Compensation: Adjustment to Compensation [Axis] Purchases of property and equipment Payments to Acquire Machinery and Equipment Share Repurchase Program [Axis] Share Repurchase Program [Axis] Income Tax Expense (benefit), increase Income Tax Expense (Benefit), Continuing Operations, Adjustment of Deferred Tax (Asset) Liability Public Offering Public Offering [Member] Public Offering Restructuring Cost and Reserve [Line Items] Restructuring Cost and Reserve [Line Items] 2028 Purchase, Contractual And Restructuring Plan Obligation, Due in Second Year Purchase, Contractual And Restructuring Plan Obligation, Due in Second Year Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] 2027 Contractual Obligation, to be Paid, Year One Underwritten Public Offering, Maximum Number Of Shares, Underwriters Option to Purchase Underwritten Public Offering, Maximum Number Of Shares, Underwriters Option to Purchase Maximum Number Of Shares, Underwriters Option to Purchase Credit Facility [Axis] Credit Facility [Axis] Restructuring Restructuring and Related Activities Disclosure [Text Block] Euro deferred shares, number of outstanding shares (in shares) Deferred Shares Share Outstanding Deferred Shares Share Outstanding Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Options, vested and expected to vest ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Collaboration Revenue, US License Collaboration Revenue, US License [Member] Collaboration Revenue, US License Name Measure Name Income Taxes Income Tax Disclosure [Text Block] Accounts payable Accounts Payable, Current Pay vs Performance Disclosure [Line Items] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Lessee, Operating Lease, Liability, to be Paid, after Year Three Lessee, Operating Lease, Liability, to be Paid, after Year Two Lessee, Operating Lease, Liability, to be Paid, after Year Two Milestone achievement, Clinical milestone Milestone Achievement, Clinical Milestone Milestone Achievement, Clinical Milestone -recognized where milestone was achieved at the end of the period presented. Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Additional Paid-in Capital Additional Paid-in Capital [Member] Entity Filer Category Entity Filer Category Supplemental disclosures of cash flow information Supplemental Cash Flow Elements [Abstract] Thereafter Purchase, Contractual And Restructuring Plan Obligation, Due After Fourth Year Purchase, Contractual And Restructuring Plan Obligation, Due After Fourth Year Proceeds from Issuance of Common Stock, Gross Proceeds from Issuance of Common Stock, Gross Proceeds from Issuance of Common Stock, Gross Dublin, Ireland Dublin, Ireland [Member] Dublin, Ireland [Member] Collaboration Agreement, Total Transaction Price Collaboration Agreement, Total Transaction Price, PRX005 US Collaboration Agreement, Total Transaction Price, PRX005 US Contractual Obligation, to be Paid, Year Five Contractual Obligation, to be Paid, Year Five Name Trading Arrangement, Individual Name 2026 Restructuring Plan Obligation, To Be Paid, Remainder Of Fiscal Year Restructuring Plan Obligation, To Be Paid, Remainder Of Fiscal Year Contractual obligations under license agreements Contractual Obligation, Fiscal Year Maturity [Abstract] Cash and cash equivalents Cash and Cash Equivalent Number of votes Number of Votes Number of Votes Morristown, NJ Morristown, NJ [Member] Morristown, NJ Foreign Exchange Restructuring Reserve, Foreign Currency Translation Gain (Loss) Company Selected Measure Amount Company Selected Measure Amount Purchase and Contractual Obligation, Due After Fifth Year Purchase and Contractual Obligation, Due After Fifth Year Purchase and Contractual Obligation, Due After Fifth Year Share Purchase Agreement, Upfront Payment Share Purchase Agreement, Upfront Payment Share Purchase Agreement, Upfront Payment Depreciation Depreciation, Depletion and Amortization Term of contract (in years) Lease Agreement, Term of Contract Lease Agreement, Term of Contract Non-Cash Financing -Receivable From Option Exercises Non-Cash Financing -Receivable From Option Exercises Non-Cash Financing -Receivable From Option Exercises Entity Address, Address Line Two Entity Address, Address Line Two Current assets: Assets, Current [Abstract] Operating lease, weighted average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Non-PEO NEO Non-PEO NEO [Member] Entity Address, Address Line One Entity Address, Address Line One Right-of-use assets obtained in exchange for lease obligations Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Restricted stock units vested fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Sale of Ordinary Shares [Line Items] Subsidiary, Sale of Stock [Line Items] Provision for income taxes Income tax expense (benefit) Income Tax Expense (Benefit) Purchase obligation Total Purchase Obligation Award Timing Method Award Timing Method [Text Block] Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Numerator: Net Income (Loss) Attributable to Parent [Abstract] Net Income (Loss) Net income (loss) Net income (loss) Net Income (Loss) Attributable to Parent Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Research and development Research And Development Expense, Adjusted Research And Development Expense, Adjusted Balance Sheet Location [Axis] Location, Statement of Financial Position, Balance [Axis] Proceeds from Sale of Property, Plant, and Equipment Proceeds from Sale of Property, Plant, and Equipment Statement [Table] Statement [Table] Restatement Determination Date: Restatement Determination Date [Axis] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Weighted Average Exercise Price, Exercisable (in dollars per shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Foreign currency transaction loss Foreign Currency Transaction Loss, before Tax Collaboration Agreement, Extension fee per extension period Collaboration Agreement, Extension Fee per Extension Period Collaboration Agreement, Extension Fee per Extension Period (12-Months) Collaboration Agreement, Option fees and Milestone payments, Payment Term Collaboration Agreement, Option Fees and Milestone Payments, Payment Term Collaboration Agreement, Option Fees and Milestone Payments, Payment Term Collaboration Agreement, Total Transaction Price, PRX005 Global Collaboration Agreement, Total Transaction Price, tau/BMS-986446 Global Collaboration Agreement, Total Transaction Price, tau/BMS-986446 Global Other Research And Development Other Research And Development [Member] Other Research And Development Research Reimbursement Research Reimbursement [Member] Research Reimbursement [Member] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]