v3.26.1
Segment Reporting - Schedule of Functional Operating Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Mar. 31, 2026
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2026
Jun. 30, 2025
Research and Development Expenses            
Research and development expenses $ 12,522   $ 18,391   $ 25,527 $ 43,769
General and Administrative Expenses            
General and administrative expenses 6,417   5,541   12,355 11,484
Operating loss (18,939)   (23,932)   (37,882) (55,253)
Other income (expense):            
Interest income 1,093   842   2,343 1,964
Other (expense) income, net 50   3   (5) 0
Total other income, net 1,143   845   2,338 1,964
Income tax expense (16)   0   (31) 0
Net loss (17,812) $ (17,763) (23,087) $ (30,202) (35,575) (53,289)
Location, Statement of Income, Balance [Axis]: us-gaap:GeneralAndAdministrativeExpense | Personnel-related (Including Stock-based Compensation)            
General and Administrative Expenses            
General and administrative expenses 3,733   3,087   7,189 6,682
Location, Statement of Income, Balance [Axis]: us-gaap:GeneralAndAdministrativeExpense | Facility Related and Other            
General and Administrative Expenses            
General and administrative expenses 494   536   1,007 992
Location, Statement of Income, Balance [Axis]: us-gaap:GeneralAndAdministrativeExpense | Other General and Administrative            
General and Administrative Expenses            
General and administrative expenses 2,190   1,918   4,159 3,810
Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense | PGN-EDODM1            
Research and Development Expenses            
Research and development expenses 5,783   4,688   11,779 16,396
Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense | PGN-EDO51            
Research and Development Expenses            
Research and development expenses 12   4,582   32 7,998
Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense | Platform and External            
Research and Development Expenses            
Research and development expenses 136   65   222 435
Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense | Personnel-related (Including Stock-based Compensation)            
Research and Development Expenses            
Research and development expenses 4,735   5,841   9,850 13,312
Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense | Facility Related and Other            
Research and Development Expenses            
Research and development expenses 1,207   1,318   2,417 2,581
Location, Statement of Income, Balance [Axis]: us-gaap:ResearchAndDevelopmentExpense | Other Research and Development Expenses            
Research and Development Expenses            
Research and development expenses $ 649   $ 1,897   $ 1,227 $ 3,047