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  <xs:element id="kvue_AdjustedOperatingIncome" abstract="false" name="AdjustedOperatingIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_RestructuringAndOperatingModelOptimizationInitiatives" abstract="false" name="RestructuringAndOperatingModelOptimizationInitiatives" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_IncomeFromConversionOfShareBasedAwards" abstract="false" name="IncomeFromConversionOfShareBasedAwards" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_FoundersShareBasedAwardsExpense" abstract="false" name="FoundersShareBasedAwardsExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_PendingTransactionAndOtherRelatedCosts" abstract="false" name="PendingTransactionAndOtherRelatedCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_SaleAndLeasebackTransactionRelatedExpense" abstract="false" name="SaleAndLeasebackTransactionRelatedExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_DepreciationDepletionAndAmortizationAdjusted" abstract="false" name="DepreciationDepletionAndAmortizationAdjusted" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_InformationTechnologyAndProjectRelatedCostsMember" abstract="true" name="InformationTechnologyAndProjectRelatedCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="kvue_A2024MultiYearRestructuringInitiativeMember" abstract="true" name="A2024MultiYearRestructuringInitiativeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="kvue_A2026RestructuringInitiativeMember" abstract="true" name="A2026RestructuringInitiativeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="kvue_RestructuringAndRelatedCostExpectedCostPercent" abstract="false" name="RestructuringAndRelatedCostExpectedCostPercent" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="kvue_RestructuringCostsAndOtherCharges" abstract="false" name="RestructuringCostsAndOtherCharges" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="kvue_ITAndProjectRelatedCostsMember" abstract="true" name="ITAndProjectRelatedCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
