v3.26.1
Segment Reporting (Details)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2026
USD ($)
operatingSegment
segment
Jun. 30, 2025
USD ($)
Segment Reporting [Abstract]        
Number of operating segment | operatingSegment     1  
Number of reportable segment | segment     1  
Segment Reporting [Line Items]        
Product revenues, net $ 425,486 $ 107,415 $ 731,450 $ 200,238
Cost of product revenues (excluding amortization of intangible assets) 67,212 28,075 114,632 49,353
Research and development 210,034 177,190 419,519 329,767
Amortization of intangible assets 2,081 1,263 4,162 2,526
Change in fair value of contingent consideration (99,760) 59,000 (146,721) 77,300
Investment income (10,979) (13,225) (23,019) (27,131)
Interest expense 20,273 21,245 40,355 42,814
Provision for income taxes 1,869 1,243 3,334 2,155
Net loss (13,242) (321,686) (176,805) (578,269)
ARIKAYCE external R&D expenses        
Segment Reporting [Line Items]        
Product revenues, net 116,316 107,415 214,426 200,238
Reportable Segment        
Segment Reporting [Line Items]        
Product revenues, net 425,486 107,415 731,450 200,238
Cost of product revenues (excluding amortization of intangible assets) 67,212 28,075 114,632 49,353
R&D compensation and benefit-related expenses 69,080 56,389 141,220 109,947
SG&A compensation and benefit-related expenses 70,520 51,320 145,313 106,156
Other segment items 207,425 127,650 417,913 247,345
Depreciation 3,179 2,484 6,113 4,367
Amortization of intangible assets 2,081 1,263 4,162 2,526
Change in fair value of contingent consideration (99,760) 59,000 (146,721) 77,300
Investment income (10,979) (13,225) (23,019) (27,131)
Interest expense 20,273 21,245 40,355 42,814
Provision for income taxes 1,869 1,243 3,334 2,155
Net loss (13,242) (321,686) (176,805) (578,269)
Reportable Segment | TPIP external R&D expenses        
Segment Reporting [Line Items]        
Research and development 38,935 20,649 76,276 29,802
Reportable Segment | Brensocatib external R&D expenses        
Segment Reporting [Line Items]        
Research and development 13,829 33,560 32,313 54,221
Reportable Segment | ARIKAYCE external R&D expenses        
Segment Reporting [Line Items]        
Research and development 6,228 11,003 14,850 23,124
Reportable Segment | Other external R&D expenses        
Segment Reporting [Line Items]        
Research and development $ 48,836 $ 28,445 $ 81,514 $ 56,528