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The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term.

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The risk-free interest rate assumption that is used in valuing an option on its own shares.

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Number of shares authorized for issuance under share-based payment arrangement.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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Number of options outstanding, including both vested and non-vested options.

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Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Stock-Based Awards (Details) - shares	6 Months Ended
Stock-Based Awards (Details) - shares	Jun. 30, 2026	Jun. 30, 2025	Dec. 31, 2025	Nov. 30, 2024
Stock Based Awards
Options outstanding	15,392,992		11,269,399
Stock Option Valuation
Risk-free interest rate (as a percent)	3.97%	4.32%
Expected term (in years)	6 years 2 months 12 days	6 years 2 months 12 days
Expected volatility (as a percent)	72.18%	82.71%
Expected dividend yield (as a percent)	0.00%	0.00%
Award remained available for grant under 2015 plan
Stock Based Awards
Number of shares available for grant		3,957,232
Award remained available for grant under 2015 plan and 2012 plan
Stock Based Awards
Number of shares available for grant		12,575,761
2025 Equity Incentive Plan
Stock Based Awards
Number of shares available for grant	6,754,427
Number of shares authorized		25,532,993
Common shares reserved for future issuance		9,000,000
Options outstanding	5,651,560
2025 Equity Incentive Plan \| Restricted stock units
Stock Based Awards
Number of shares outstanding	1,874,582
2024 Inducement Plan
Stock Based Awards
Number of shares available for grant	502,830
Number of shares authorized				2,000,000
Options outstanding	1,172,000
2024 Inducement Plan \| Restricted stock units
Stock Based Awards
Number of shares outstanding	250,875
2017 Inducement Plan
Stock Based Awards
Options outstanding	323,500
2015 Equity Incentive Plan
Stock Based Awards
Number of shares available for grant	0	0
Options outstanding	8,245,932
2015 Equity Incentive Plan \| Restricted stock units
Stock Based Awards
Number of shares outstanding	1,315,806