Stockholders' Equity (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
|
| Increase (Decrease) in Stockholders' Equity | ||||||
| Balance, beginning | $ 456,226 | $ 527,165 | $ 702,981 | $ 747,005 | $ 527,165 | $ 747,005 |
| Balance, beginning (in shares) | 66,549,442 | 66,549,442 | ||||
| Shares issued under stock option and employee stock purchase plans | 825 | $ 327 | 63 | 202 | ||
| Shares issued in underwritten offering, net | 323,832 | |||||
| Stock-based compensation | 8,408 | 8,523 | 9,191 | 9,316 | ||
| Unrealized (loss) gain on marketable securities | (1,224) | (1,104) | (229) | 254 | $ (2,328) | 25 |
| Net Income (Loss) | (73,503) | (78,685) | (56,600) | (53,796) | (152,188) | (110,396) |
| Balance, ending | $ 714,564 | 456,226 | 655,406 | 702,981 | $ 714,564 | 655,406 |
| Balance, ending (in shares) | 78,500,173 | 78,500,173 | ||||
| Common Stock | ||||||
| Increase (Decrease) in Stockholders' Equity | ||||||
| Balance, beginning | $ 67 | $ 67 | $ 66 | $ 66 | $ 67 | $ 66 |
| Balance, beginning (in shares) | 66,568,971 | 66,549,442 | 66,384,191 | 66,374,549 | 66,549,442 | 66,374,549 |
| Shares issued under stock option and employee stock purchase plans (in shares) | 34,452 | 19,529 | 10,050 | 9,642 | ||
| Shares issued in underwritten offering, net | $ 12 | |||||
| Shares issued in underwritten offering, net (in shares) | 11,896,750 | |||||
| Balance, ending | $ 79 | $ 67 | $ 66 | $ 66 | $ 79 | $ 66 |
| Balance, ending (in shares) | 78,500,173 | 66,568,971 | 66,394,241 | 66,384,191 | 78,500,173 | 66,394,241 |
| Additional Paid-In Capital | ||||||
| Increase (Decrease) in Stockholders' Equity | ||||||
| Balance, beginning | $ 2,346,303 | $ 2,337,453 | $ 2,308,367 | $ 2,298,849 | $ 2,337,453 | $ 2,298,849 |
| Shares issued under stock option and employee stock purchase plans | 825 | 327 | 63 | 202 | ||
| Shares issued in underwritten offering, net | 323,820 | |||||
| Stock-based compensation | 8,408 | 8,523 | 9,191 | 9,316 | ||
| Balance, ending | 2,679,356 | 2,346,303 | 2,317,621 | 2,308,367 | 2,679,356 | 2,317,621 |
| Accumulated Other Comprehensive Income | ||||||
| Increase (Decrease) in Stockholders' Equity | ||||||
| Balance, beginning | 2,522 | 3,626 | 3,568 | 3,314 | 3,626 | 3,314 |
| Unrealized (loss) gain on marketable securities | (1,224) | (1,104) | (229) | 254 | ||
| Balance, ending | 1,298 | 2,522 | 3,339 | 3,568 | 1,298 | 3,339 |
| Accumulated Deficit | ||||||
| Increase (Decrease) in Stockholders' Equity | ||||||
| Balance, beginning | (1,892,666) | (1,813,981) | (1,609,020) | (1,555,224) | (1,813,981) | (1,555,224) |
| Net Income (Loss) | (73,503) | (78,685) | (56,600) | (53,796) | ||
| Balance, ending | $ (1,966,169) | $ (1,892,666) | $ (1,665,620) | $ (1,609,020) | $ (1,966,169) | $ (1,665,620) |
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- Definition Amount of increase to additional paid-in capital (APIC) for recognition of cost for award under share-based payment arrangement. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Total number of common shares of an entity that have been sold or granted to shareholders (includes common shares that were issued, repurchased and remain in the treasury). These shares represent capital invested by the firm's shareholders and owners, and may be all or only a portion of the number of shares authorized. Shares issued include shares outstanding and shares held in the treasury. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period. No definition available.
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount, after tax and before adjustment, of unrealized holding gain (loss) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale). Excludes unrealized gain (loss) on investment in debt security measured at amortized cost (held-to-maturity) from transfer to available-for-sale. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Number of shares issued during the period as a result of an employee stock purchase plan. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Number of shares of stock issued attributable to transactions classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Aggregate change in value for stock issued during the period as a result of employee stock purchase plan. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Value of shares of stock issued attributable to transactions classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of equity (deficit) attributable to parent. Excludes temporary equity and equity attributable to noncontrolling interest. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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