v3.26.1
Segment Information - Schedule Of Segment Reporting (Detail) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Mar. 31, 2026
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2026
Jun. 30, 2025
Segment Reporting [Line Items]            
Collaboration revenue $ 7,659   $ 14,245   $ 22,707 $ 30,872
Type of Revenue [Extensible List]         us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Research and development 82,595   97,035   $ 163,332 $ 205,462
General and administrative 37,824   27,206   72,667 56,213
Interest income (5,797)   (7,402)   (11,002) (16,005)
Net loss (106,634) $ (96,231) (101,255) $ (114,329) (202,865) (215,584)
Operating Segments [Member]            
Segment Reporting [Line Items]            
Collaboration revenue $ 7,659   $ 14,245   $ 22,707 $ 30,872
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember   us-gaap:LicenseAndServiceMember   us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Research and development $ 82,595   $ 97,035   $ 163,332 $ 205,462
General and administrative [1] 37,824   27,206   72,667 56,213
Interest income (5,797)   (7,402)   (11,002) (16,005)
Other segment information [2] (329)   (1,339)   575 786
Net loss (106,634)   (101,255)   (202,865) (215,584)
Nex-z [Member] | Operating Segments [Member]            
Segment Reporting [Line Items]            
Research and development 18,268   23,958   38,512 47,088
Other Research And Development [Member] | Operating Segments [Member]            
Segment Reporting [Line Items]            
Research and development [3] 54,758   61,024   107,109 135,653
Lonvo-Z [Member] | Operating Segments [Member]            
Segment Reporting [Line Items]            
Research and development $ 9,569   $ 12,053   $ 17,711 $ 22,721
[1] Includes stock-based compensation of $8.6 million and $14.5 million for the three and six months ended June 30, 2026, respectively, and $8.0 million and $17.2 million for the three and six months ended June 30, 2025, respectively, as disclosed within Note 10, “Stock-Based Compensation.”
[2] Includes change in fair value of investments as disclosed in the Company’s condensed consolidated statements of operations and comprehensive loss.
[3] Includes unallocated research and development expenses, including stock-based compensation of $9.4 million and $17.0 million for the three and six months ended June 30, 2026, respectively, and $14.1 million and $26.7 million for the three and six months ended June 30, 2025, respectively, as disclosed within Note 10, “Stock-Based Compensation.”