0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Balance Sheets (Parentheticals) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Operations (Parentheticals) link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Operations (Parentheticals) link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - Condensed Consolidated Statements of Shareholders’ Equity link:presentationLink link:calculationLink link:definitionLink 9952157 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Description of Business and Liquidity link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Cash, Cash Equivalents and Marketable Securities link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Equity Method Investments link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Recent Transactions and Developments link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Certain Balance Sheet Components link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Shareholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Share-Based Compensation link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Net Loss per Common Share link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Cash, Cash Equivalents and Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Certain Balance Sheet Components (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Share-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Net Loss per Common Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Segment Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Description of Business and Liquidity (Details) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Summary of Significant Accounting Policies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Summary of Significant Accounting Policies - Schedule of Cash, Cash Equivalents, and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Cash, Cash Equivalents and Marketable Securities - Schedule of Cash, Cash Equivalents, and Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Cash, Cash Equivalents, and Marketable Securities - Schedule of Unrealized Positions for Held-to-Maturity Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Cash, Cash Equivalents, and Marketable Securities - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Cash, Cash Equivalents, and Marketable Securities - Schedule of Marketable Securities as Level 2 Measurements Within the Fair Value Hierarchy (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Equity Method Investments - Investment in Arbutus (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Equity Method Investments - Investments in Datavant (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Recent Transactions and Developments (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Certain Balance Sheet Components - Schedule of Accrued Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Certain Balance Sheet Components - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Shareholders' Equity (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Share-Based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Share-Based Compensation - Schedule of Activity for Stock Options and Performance Stock Options (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Share-Based Compensation - Schedule of Activity for RSUs and PSUs (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Fair Value Measurements - Schedule of Assets and Liabilities are Measured at Fair Value on Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Fair Value Measurements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Fair Value Measurements - Schedule of Changes in Fair Value of the Level 3 Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Fair Value Measurements - Schedule of Changes in Fair Value of the Level 3 Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Fair Value Measurements - Schedule of Investment in Datavant (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Net Loss per Common Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Segment Information - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Segment Information - Schedule of Significant Segment Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Segment Information - Schedule of Significant Segment Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Subsequent Events (Details) link:presentationLink link:calculationLink link:definitionLink