| Security Type | Security Class Title | Fee Calculation or Carry Forward Rule | Amount Registered(1) | Proposed Maximum Offering Price Per Unit | Maximum Aggregate Offering Price(2) | Fee Rate | Amount of Registration Fee(3) | Carry Forward Form Type | Carry Forward File Number | Carry Forward Initial effective date | Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward | |
| Newly Registered Securities | ||||||||||||
| | |
| | — | — | — | — | — | — | — | — | — |
| | |
| | — | — | — | — | — | — | — | — | — |
| | |
| | — | — | — | — | — | — | — | — | — |
| | |
| | — | — | — | — | — | — | — | — | — |
| | |
| | — | — | — | — | — | — | — | — | — |
| | |
— | | — | — | $ | | $ | — | — | — | — |
| Fees Previously Paid | — | — | — | — | — | — | — | — | — | — | — | — |
| Carry Forward Securities | ||||||||||||
| Carry Forward Securities | — | — | — | — | — | — | — | — | — | — | — | |
| Total Offering Amounts | — | $ | $ | — | — | — | — | |||||
| Total Fees Previously Paid | — | — | — | | — | — | — | — | ||||
| Total Fee Offsets | — | — | — | $ | — | — | — | — | ||||
| Net Fee Due | $ | |||||||||||
| (1) | The registrant is registering an indeterminate number of ordinary shares, warrants, purchase contracts and units and an indeterminate principal amount of debt securities. Any securities registered hereunder may be sold separately or as units with other securities registered hereunder. The securities registered also include such indeterminate amounts and numbers of ordinary shares as may be issuable upon conversion, redemption, exchange, exercise or settlement of any securities registered hereunder, including under any applicable anti-dilution provisions. In addition, pursuant to Rule 416(a) under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional number of securities as may be issued from time to time to prevent dilution as a result of a distribution, split, combination, or similar transaction. Includes consideration to be received by the registrant, if applicable, for registered securities that are issuable upon exercise, conversion or exchange of other registered securities. |
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(2)
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Estimated solely for the purpose of calculating the registration fee. The aggregate maximum offering price of all securities issued pursuant to this registration statement will not exceed $250,000,000. The proposed maximum aggregate offering price per class of security will be determined from time to time by the registrant in connection with the issuance by the registrant of the securities registered hereunder and is not specified as to each class of security.
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(3)
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Calculated pursuant to Rule 457(o) under the Securities Act based on the proposed maximum aggregate offering price of all securities listed.
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| Line Item Type | Registrant or Filer Name | Notes | Form or Filing Type | File Number | Initial Filing Date | Filing Date | Fee Offset Claimed | Security Type Associated with Fee Offset Claimed | Security Title Associated with Fee Offset Claimed | Unsold Securities Associated with Fee Offset Claimed | Unsold Aggregate Offering Amount Associated with Fee Offset Claimed | Fee Paid with Fee Offset Source |
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| | | (1) | | | | — | $ | | (1) | Unallocated (Universal) Shelf | $ | |
| | | (2) | | | — | — | — | — | — | — | $ | |
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Explanation for the basis of the claimed offset:
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| (1) | On June 30, 2023, the Registrant initially filed
a registration statement on Form F-3 (File No. 333-273058), which was declared
effective on July 11, 2023 (the “Prior Registration Statement”),
registering securities with a maximum aggregate offering price of $250,000,000,
for which the Registrant paid an aggregate registration fee of $27,550.00
(calculated at the filing fee rate of $110.20 per $1,000,000, which was in
effect at the time of the filing of the Prior Registration Statement). Pursuant to Rule 415(a)(5) under the Securities Act, the Prior Registration Statement has expired. At the time of the expiration of the Prior Registration Statement, the Registrant had sold an aggregate of $189,335,707.25 of securities thereunder (consisting of (i) $29,993,250 of ordinary shares and pre-funded warrants sold in an underwritten public offering completed in February 2025, (ii) $150,000,000 of ordinary shares sold in an underwritten public offering completed in May 2026 and (iii) $9,342,457.25 of ordinary shares sold under an at-the-market offering program), and there remained unsold $60,664,292.75 of securities registered under the Prior Registration Statement (the “Unsold Securities”), for which the Registrant paid an aggregate registration fee of $6,685.21 (calculated at the filing fee rate that was in effect at the time of the filing of the Prior Registration Statement). |
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Offset Note(s)
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| (2) | Pursuant to Rule 457(p), the Registrant is
offsetting $6,685.21 of the filing fees associated with the filing of this
registration statement with the fees previously paid to register the Unsold
Securities under the Prior Registration Statement. |