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          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesCurrent" xlink:label="us-gaap_OtherLiabilitiesCurrent"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/country/2025/country-2025.xsd#country_CN" xlink:label="country_CN"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
          <link:loc xlink:type="locator" xlink:href="mksi-20260630.xsd#mksi_BusinessCombinationPricePerShareOfCommonStockInCash" xlink:label="mksi_BusinessCombinationPricePerShareOfCommonStockInCash"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfFinancingCosts" xlink:label="us-gaap_PaymentsOfFinancingCosts"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAcquiredFromAcquisition" xlink:label="us-gaap_CashAcquiredFromAcquisition"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherCurrentLiabilitiesMember" xlink:label="us-gaap_OtherCurrentLiabilitiesMember"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DisaggregationOfRevenueLineItems" xlink:label="us-gaap_DisaggregationOfRevenueLineItems"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherSundryLiabilitiesCurrent" xlink:label="us-gaap_OtherSundryLiabilitiesCurrent"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLossAbstract" xlink:label="us-gaap_NetIncomeLossAbstract"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable" xlink:label="us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1" xlink:label="us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillImpairedAccumulatedImpairmentLoss" xlink:label="us-gaap_GoodwillImpairedAccumulatedImpairmentLoss"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityEmergingGrowthCompany" xlink:label="dei_EntityEmergingGrowthCompany"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis"/>
          <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet"/>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EquitySecuritiesFvNiCurrentAndNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Equity securities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EquitySecuritiesFvNiCurrentAndNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity Securities, FV-NI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EquitySecuritiesFvNiCurrentAndNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Equity Securities, FV-NI, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds from Sale of Property, Plant, and Equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Proceeds from Sale of Property, Plant, and Equipment, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Proceeds from sale of long-lived assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segments [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestructuringReserve_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Restructuring Reserve</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestructuringReserve_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Restructuring Reserve, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestructuringReserve_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestructuringReserve_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">End of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Revenues From External Customers And Long Lived Assets [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Revenues from External Customers and Long-Lived Assets [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityIncorporationStateCountryCode_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Incorporation, State or Country Code</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityIncorporationStateCountryCode_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Incorporation, State or Country Code</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Preferred Stock, Shares Issued, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Preferred stock, shares issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Preferred Stock, Shares Issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BalanceSheetLocationDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Balance Sheet Location</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BalanceSheetLocationDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of Financial Position Location, Balance [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BaseRateBorrowingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Base rate borrowings member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BaseRateBorrowingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Base Rate Borrowings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BaseRateBorrowingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Base Rate Borrowings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Supplemental non-cash financing activities:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentInterestRateFairValueHedgeAssetAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Interest Rate Fair Value Hedge Asset At Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentInterestRateFairValueHedgeAssetAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current interest rate fair value hedge asset at fair value.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentInterestRateFairValueHedgeAssetAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Derivatives-interest rate hedge - current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfDebtInstrumentsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Long-Term Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfDebtInstrumentsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Long-Term Debt Instruments [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCurrentReportingStatus_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Current Reporting Status</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCurrentReportingStatus_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Current Reporting Status</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossNotDesignatedAsHedgingInstrumentsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivative Instruments Gain Loss Not Designated As Hedging Instruments [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossNotDesignatedAsHedgingInstrumentsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Instruments Gain Loss Not Designated As Hedging Instruments [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossNotDesignatedAsHedgingInstrumentsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Derivative Instruments Gain Loss Not Designated As Hedging Instruments [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_JP_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Japan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_JP_lbl" xlink:role="http://www.xbrl.org/2003/role/label">JAPAN</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsPayableAmountPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash dividend to be paid</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsPayableAmountPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Dividends Payable, Amount Per Share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillGross_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance, Goodwill Gross Carrying Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillGross_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance, Goodwill Gross Carrying Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillGross_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill, Gross</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueInputsLevel2Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Significant Other Observable Inputs (Level 2) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueInputsLevel2Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value, Inputs, Level 2 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commitments and Contingencies</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commitments and Contingencies Disclosure [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashFlowHedgingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash Flow Hedging [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashFlowHedgingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Flow Hedging [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashFlowHedgingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Cash Flow Hedges [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesAuthorized_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common stock, shares authorized</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesAuthorized_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, Shares Authorized</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Asset, Expected Amortization, Year Four</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2030</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareBasicAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share, Basic [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareBasicAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Net income per share:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ProductOrServiceAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Product and Service</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ProductOrServiceAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Product and Service [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentFiscalPeriodFocus_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Fiscal Period Focus</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentFiscalPeriodFocus_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Fiscal Period Focus</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNoncurrentLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other Noncurrent Liabilities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNoncurrentLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Noncurrent Liabilities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentInterestRateStatedPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentInterestRateStatedPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Interest Rate, Stated Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenueFromContractWithCustomerAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue from Contract with Customer [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityShellCompany_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Shell Company</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityShellCompany_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Shell Company</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsCommonStockCash_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Cash dividend</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsCommonStockCash_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Dividends, Common Stock, Cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleDebtMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Convertible Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleDebtMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Debt [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ServiceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Services [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ServiceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Service [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash not subject to fair value disclosure requirements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash and Cash Equivalent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashAndCashEquivalentsAtCarryingValue_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Cash and Cash Equivalents, at Carrying Value, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeited_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Vested or forfeited</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeited_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Share based compensation arrangement by share based payment award, equity instruments other than options, vested and forfeited.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeited_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested And Forfeited</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeited_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Vested or forfeited</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Contractual Maturities of Debt Obligations</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NumberOfReportingUnits_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of Reporting Units</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NumberOfReportingUnits_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of reporting units</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElectronicsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Electronics</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElectronicsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Electronics [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElectronicsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Electronics [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LitigationSettlementExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Litigation Settlement, Fee Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LitigationSettlementExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Legal settlement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Common Stock, Shares, Issued, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common stock, shares issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, Shares, Issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfShortTermDebtTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Short Term Debt [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfShortTermDebtTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-Term Debt [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Asset Class</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Asset Class [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Statement [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Comprehensive (Income) Loss, Defined Benefit Plan, after Tax and Reclassification Adjustment, Attributable to Parent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Comprehensive (Income) Loss, Defined Benefit Plan, after Tax and Reclassification Adjustment, Attributable to Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Unrecognized pension (loss) gain</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InvestmentTaxCredit_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Investment Tax Credit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InvestmentTaxCredit_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Advanced manufacturing investment credit in other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FacilityInSouthKoreaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Facility in South Korea [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FacilityInSouthKoreaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Facility in South Korea [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FacilityInSouthKoreaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Facility in South Korea.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AociIncludingPortionAttributableToNoncontrollingInterestMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accumulated Other Comprehensive (Loss) Income [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AociIncludingPortionAttributableToNoncontrollingInterestMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">AOCI Including Portion Attributable to Noncontrolling Interest [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FederalFundsRateMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Federal Funds Rate [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FederalFundsRateMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Federal Funds Rate [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FederalFundsRateMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Federal funds rate.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesGross_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Total purchase price, net of cash and cash equivalents acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesGross_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Business acquisition, total cash consideration</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesGross_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Payments to Acquire Businesses, Gross</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesGross_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total purchase price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PrepaymentPremiumPercentageOfAggregatePrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Percentage of prepayment premium</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PrepaymentPremiumPercentageOfAggregatePrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Prepayment premium percentage of aggregate principal amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PrepaymentPremiumPercentageOfAggregatePrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Prepayment Premium Percentage of Aggregate Principal Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PrepaymentPremiumPercentageOfAggregatePrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Prepayment premium percentage of aggregate principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquipmentSolutionsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Equipment Solutions [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquipmentSolutionsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equipment Solutions [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InitialCommitmentFeePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Initial commitment fee percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InitialCommitmentFeePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Initial Commitment Fee Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InitialCommitmentFeePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Initial commitment fee percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Statement [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionAcquireeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Business Acquisition, Acquiree</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionAcquireeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherExpenseMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other Expense, Net [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherExpenseMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Expense [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityFilerCategory_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Entity Filer Category</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityFilerCategory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Filer Category</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentIssuedPrincipalOptionToPurchase_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument issued principal option to purchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentIssuedPrincipalOptionToPurchase_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument Issued Principal Option To Purchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentIssuedPrincipalOptionToPurchase_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt Instrument Issued Principal Option To Purchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsCurrentGross_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt issuance costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsCurrentGross_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Issuance Costs, Gross, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsCurrentGross_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Debt issuance costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reclassification from AOCI, Current Period, Net of Tax, Attributable to Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amounts reclassified out of AOCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Amounts reclassified out of AOCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodTwoMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption, Period Two [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodTwoMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2030 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodTwoMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Event of Certain Developments Affecting Taxation [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total liabilities and stockholders&#8217; equity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesAndStockholdersEquity_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities and Equity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt Instrument [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Foreign Currency Contract, Asset, Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignCurrencyContractAssetFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives-foreign currency options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Maturity, Year Three</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2029</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestructuringCostAndReserveAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Restructuring Type [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PropertyPlantAndEquipmentByTypeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Lived Tangible Asset [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Foreign currency translation adjustments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentFrequencyOfPeriodicPayment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument frequency of periodic payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentFrequencyOfPeriodicPayment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Frequency of Periodic Payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DiscountRateFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Discount rate future undiscounted cash flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DiscountRateFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Discount Rate Future Undiscounted Cash Flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DiscountRateFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Discount Rate Future Undiscounted Cash Flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Hedging Relationship</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Hedging Relationship [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TradeNamesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade Names [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TradeNamesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trade Names [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Company's Restructuring Activity</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProceedsFromIssuanceOfDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net proceeds from offering</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquipmentSolutionsBusinessMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Equipment Solutions Business [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquipmentSolutionsBusinessMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equipment Solutions Business [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquipmentSolutionsBusinessMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">ESB [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashAndCashEquivalentsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash and cash equivalents</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNonCurrentAccruedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current accrued compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IntangibleAssetsUsefulLifeFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Intangible assets useful life future undiscounted cash flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IntangibleAssetsUsefulLifeFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Intangible Assets Useful Life Future Undiscounted Cash Flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IntangibleAssetsUsefulLifeFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Intangible assets useful life future undiscounted cash flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsequent Event [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateralCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives interest rate hedge - current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateralCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Fair Value Of Derivative Liability Amount Not Offset Against Collateral Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateralCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Derivative Fair Value Of Derivative Liability Amount Not Offset Against Collateral Current.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RamakumarMayampurathMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Ramakumar Mayampurath [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RamakumarMayampurathMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Ramakumar Mayampurath.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RamakumarMayampurathMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Ramakumar Mayampurath</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NotesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">2034 Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NotesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">2034 Notes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NotesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2034 Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeAssetNotionalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Asset, Notional Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeAssetNotionalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net notional value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Goodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Goodwill</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Goodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance, Goodwill Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Goodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance, Goodwill Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Goodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Goodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Goodwill, net of accumulated impairment and foreign currency translation, at March 31, 2025</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Goodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Goodwill, net of accumulated impairment and foreign currency translation adjustments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNoncashIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNoncashIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNoncashIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Noncash Income (Expense)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNoncashIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Noncash Income (Expense), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EffectiveIncomeTaxRateContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Effective Income Tax Rate Reconciliation, Percent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EffectiveIncomeTaxRateContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Effective tax rates</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EffectiveIncomeTaxRateContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Effective Income Tax Rate Reconciliation, Percent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityIncreaseDecreaseForPeriodNet_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Line of Credit Facility, Increase (Decrease), Net, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityIncreaseDecreaseForPeriodNet_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Line of Credit Facility, Increase (Decrease), Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityIncreaseDecreaseForPeriodNet_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increased available borrowing capacity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AvailableForSaleSecuritiesDebtSecuritiesNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Securities, Available-for-Sale, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AvailableForSaleSecuritiesDebtSecuritiesNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Long-term investments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_SegmentGeographicalDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Geographical</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_SegmentGeographicalDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Geographical [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SeniorNotesDue2034Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Senior notes due 2034 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SeniorNotesDue2034Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Senior notes due 2034.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SeniorNotesDue2034Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Senior Notes Due 2034 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SeniorNotesDue2034Member_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">2034 Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReconciliationOfOperatingProfitLossFromSegmentsToConsolidatedTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReconciliationOfOperatingProfitLossFromSegmentsToConsolidatedTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Reconciliation of Gross Profit By Reportable Segment To Income Before Income Taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentExpenditureAdditionToLongLivedAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Capital expenditures</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentExpenditureAdditionToLongLivedAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment, Expenditure, Addition to Long-Lived Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="exch_JPBX_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Japan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="exch_JPBX_lbl" xlink:role="http://www.xbrl.org/2003/role/label">JPBX [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfInventoryCurrentTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Inventories</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfInventoryCurrentTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Inventory, Current [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MaterialsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Materials solutions division.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MaterialsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Materials Solutions Division [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MaterialsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Materials Solutions Division [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MaterialsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">MSD [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationProFormaInformationEarningsOrLossOfAcquireeSinceAcquisitionDateActual_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net (loss) income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationProFormaInformationEarningsOrLossOfAcquireeSinceAcquisitionDateActual_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Acquiree's Earnings (Loss) since Acquisition Date, Actual</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosuresLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivative Instruments and Hedging Activities Disclosures [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosuresLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Instruments and Hedging Activities Disclosures [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdditionalPaidInCapitalCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Additional Paid in Capital, Common Stock, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdditionalPaidInCapitalCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Additional Paid in Capital, Common Stock, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdditionalPaidInCapitalCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Additional paid-in capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdditionalPaidInCapitalCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Additional Paid in Capital, Common Stock</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FirstLienNetLeverageRatioMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">First lien net leverage ratio member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FirstLienNetLeverageRatioMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">First Lien Net Leverage Ratio [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FirstLienNetLeverageRatioMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">First Lien Net Leverage Ratio [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_MY_lbl" xlink:role="http://www.xbrl.org/2003/role/label">MALAYSIA</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_MY_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Malaysia [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CappedCallTransactionsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Capped Call Transactions [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CappedCallTransactionsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Capped call transactions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DurationOfTradingArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Duration of Trading Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DurationOfTradingArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Duration of trading arrangement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DurationOfTradingArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Duration of Trading Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetUsefulLife_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Acquired intangible assets, estimated useful lives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetUsefulLife_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Asset, Useful Life</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_VestingDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Vesting</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_VestingDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Vesting [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Net (losses) gains recognized in OCI, net of tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossAfterReclassificationAndTaxParent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Changes in value of financial instruments designated as cash flow hedges</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DisaggregationOfRevenueTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disaggregation Of Revenue [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DisaggregationOfRevenueTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disaggregation of Revenue [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Computation of Basic and Diluted Net Income Per Share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetInvestmentHedgingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Net Investment Hedging [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetInvestmentHedgingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net Investment Hedging [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TrademarksAndTradeNamesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trademarks and trade names [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TrademarksAndTradeNamesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trademarks and Trade Names [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareBasic_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Earnings Per Share, Basic, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareBasic_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Basic</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareBasic_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share, Basic</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DisaggregationOfRevenueTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Revenue from Contracts with Customers</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Gross Unrealized Gains and (Losses) Aggregated by Investment Category</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentPrincipalAmountDenominationForConversionIntoCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt instrument principal amount denomination for conversion into common stock</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentPrincipalAmountDenominationForConversionIntoCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt instrument principal amount denomination for conversion into common stock.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentPrincipalAmountDenominationForConversionIntoCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument principal amount denomination for conversion into common stock</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevolvingCreditFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revolving Lines of Credit [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevolvingCreditFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revolving Credit Facility [Member]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFour_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Long-term debt maturities repayments of principal after year four.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFour_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Thereafter</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FinitelivedIntangibleAssetsAcquired1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Acquired intangible assets, purchase price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FinitelivedIntangibleAssetsAcquired1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Assets Acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInAccountsReceivable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Accounts Receivable</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInAccountsReceivable_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Trade accounts receivable</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments to Reconcile Net Income (Loss) to Cash Provided by Operating Activities [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Adjustments to reconcile net income to net cash provided by operating activities:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_HedgingDesignationDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Hedging Designation [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revenues from External Customers and Long-Lived Assets [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenues from External Customers and Long-Lived Assets [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsPayableDateOfRecordDayMonthAndYear_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Dividend declared, shareholders of record date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsPayableDateOfRecordDayMonthAndYear_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Dividends Payable, Date of Record</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleLongTermNotesPayable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Convertible notes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleLongTermNotesPayable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Notes Payable, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryFinishedGoodsNetOfReserves_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Finished goods</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryFinishedGoodsNetOfReserves_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Inventory, Finished Goods, Net of Reserves</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GeneralMetalFinishingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">General Metal Finishing [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GeneralMetalFinishingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">General Metal Finishing [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NewRevolvingFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">New revolving facility member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NewRevolvingFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">New Revolving Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NewRevolvingFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">New Revolving Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total long-term assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Current Assets Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non current assets fair value disclosure.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Liability Assumed, Other Liability, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncurrentLiabilitiesOther_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other non-current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseDebtExcludingAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Contractual interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseDebtExcludingAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Expense, Debt, Excluding Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net unrecognized tax benefits, excluding interest and penalties, related to foreign tax positions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accounting Standards Update</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accounting Standards Update [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherLiabilitiesCurrentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Liabilities, Current [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MaterialReconcilingItemsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segment Reconciling Items [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MaterialReconcilingItemsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Reporting, Reconciling Item, Excluding Corporate Nonsegment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ConsolidationItemsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Consolidation Items</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ConsolidationItemsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Consolidation Items [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FeesAndExpensesRelatedToDebtActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fees and expenses related to debt activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FeesAndExpensesRelatedToDebtActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fees and expenses related to debt activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_FeesAndExpensesRelatedToDebtActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fees and expenses related to debt activities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElectronicsAndPackagingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Electronics and packaging.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElectronicsAndPackagingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Electronics and Packaging [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockholdersEquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stockholders&#8217; equity:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockholdersEquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity, Attributable to Parent [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TimeDepositsAndCertificatesOfDepositMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Time Deposits and Certificates of Deposit [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TimeDepositsAndCertificatesOfDepositMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Time Deposits And Certificates Of Deposit [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TimeDepositsAndCertificatesOfDepositMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Time Deposits and Certificates of Deposit [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntitySmallBusiness_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Small Business</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntitySmallBusiness_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Small Business</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Notional Amounts of Outstanding Derivative Positions [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Notional Values of Foreign Exchange Forward Contracts Outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FederalHomeLoanBanksAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Federal Home Loan Banks [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_HedgingDesignationAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Hedging Designation [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PensionAndDeferredCompensationPlanAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Pension and deferred compensation plan assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PensionAndDeferredCompensationPlanAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Pension and Deferred Compensation Plan Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PensionAndDeferredCompensationPlanAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Pension and deferred compensation plan assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Retained Earnings (Accumulated Deficit), Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Retained Earnings (Accumulated Deficit), Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Retained Earnings (Accumulated Deficit), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retained earnings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RetainedEarningsAccumulatedDeficit_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Retained Earnings (Accumulated Deficit)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SaleOfStockPricePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Sale price per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SaleOfStockPricePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Sale of Stock, Price Per Share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBSecondAmmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Usd tranche b second ammendment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBSecondAmmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Usd Tranche B Second Ammendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBSecondAmmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">USD Tranche B Second Ammendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock-Based Compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReductionInInterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reduction in interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReductionInInterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Reduction in interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReductionInInterestExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Reduction in interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Organization, Consolidation and Presentation of Financial Statements [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LeasesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Leases [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Contract with Customer, Liability, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contract with Customer, Liability</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">End of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfGoodsAndServiceExcludingDepreciationDepletionAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Cost of Goods and Service, Excluding Depreciation, Depletion, and Amortization, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfGoodsAndServiceExcludingDepreciationDepletionAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cost of Goods and Service, Excluding Depreciation, Depletion, and Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfGoodsAndServiceExcludingDepreciationDepletionAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cost of revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfGoodsAndServiceExcludingDepreciationDepletionAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Total cost of revenues (exclusive of amortization shown separately below)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_AmendmentFlag_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amendment Flag</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_AmendmentFlag_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amendment Flag</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfCustomersAccountedForTenOrMorePercentOfRevenue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of customers accounted for 10% or more of total revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfCustomersAccountedForTenOrMorePercentOfRevenue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Customers Accounted For Ten Or More Percent Of Revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfCustomersAccountedForTenOrMorePercentOfRevenue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of customers accounted for ten or more percent of revenue.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MaturitiesOfLongTermDebtAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Maturities of Long-Term Debt [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ProductsAndServicesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Product and Service</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ProductsAndServicesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Product and Service [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PhotonicsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">PSD [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PhotonicsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Photonics solutions division.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PhotonicsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Photonics Solutions Division [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PhotonicsSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Photonics Solutions Division [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfTradingDays_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of trading days.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfTradingDays_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of trading days</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfTradingDays_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Trading Days</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuroTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Euro tranche B member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuroTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Euro Tranche B [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Inventories</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Inventory Disclosure [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleDebtCappedCallsPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Convertible debt capped calls price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleDebtCappedCallsPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Debt Capped Calls Price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleDebtCappedCallsPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Convertible debt capped calls price.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesAndStockholdersEquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">LIABILITIES AND STOCKHOLDERS&#8217; EQUITY</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesAndStockholdersEquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities and Equity [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressPostalZipCode_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, Postal Zip Code</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressPostalZipCode_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, Postal Zip Code</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Provided by (Used in) Operating Activity, Including Discontinued Operation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net cash provided by operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPricePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument redemption percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPricePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption Price, Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReportingUnitDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reporting Unit [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentReportingCodmProfitLossMeasureHowUsedDescription_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common Stock [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">New Accounting Pronouncements Or Change In Accounting Principle [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accounting Standards Update and Change in Accounting Principle [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrualClassifiedCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Short-term product warranties</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrualClassifiedCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Product Warranty Accrual, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ImpairmentOfIntangibleAssetIndefiniteLivedExcludingGoodwillStatementOfIncomeOrComprehensiveIncomeExtensibleEnumeration_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired, Inventory, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Inventories</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Maturity, Year One</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2027</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_HedgingRelationshipDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Hedging Relationship</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_HedgingRelationshipDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Hedging Relationship [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Pension assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DefinedBenefitPlanAssetsForPlanBenefitsNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Assets for Plan Benefits, Defined Benefit Plan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignExchangeOptionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Foreign Exchange Option [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignExchangeOptionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives Foreign Currency Options [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressAddressLine1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, Address Line One</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressAddressLine1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, Address Line One</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateImmaterialEffect_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Change in accounting principle, accounting standards update, immaterial effect</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateImmaterialEffect_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherInterestIncomeExpenseNet_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Interest Income Expense Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherInterestIncomeExpenseNet_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other interest income expense net.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherInterestIncomeExpenseNet_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other interest (income) expense, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueByFairValueHierarchyLevelAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair Value Hierarchy and NAV</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueByFairValueHierarchyLevelAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value Hierarchy and NAV [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net income per common share:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MaximumRemainingMaturityOfForeignCurrencyDerivatives1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Maximum Remaining Maturity of Foreign Currency Derivatives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MaximumRemainingMaturityOfForeignCurrencyDerivatives1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Maximum period for hedging a portion of forecasted foreign currency denominated intercompany sales of inventory and certain foreign entities' operating expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Goodwill and Intangible Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill and Intangible Assets Disclosure [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">USD Tranche B member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">USD Tranche B [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">USD Tranche B [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BalanceSheetLocationAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Balance Sheet Location</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BalanceSheetLocationAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of Financial Position Location, Balance [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InvestmentTypeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Investment Type</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InvestmentTypeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Investment Type [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ExpenseOfRestructuringActivitiesAndOtherAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expense Of Restructuring Activities And Other [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ExpenseOfRestructuringActivitiesAndOtherAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expense Of Restructuring Activities And Other [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingLeaseRightOfUseAsset_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Operating Lease, Right-of-Use Asset</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingLeaseRightOfUseAsset_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Right-of-use assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingLeaseRightOfUseAsset_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Right-of-use assets, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentRedemptionPricePercentageOfPrincipalAmountMayRedeem_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Redemption percentage of original aggregate principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentRedemptionPricePercentageOfPrincipalAmountMayRedeem_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption Price, Percentage of Principal Amount May Redeem</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentRedemptionPricePercentageOfPrincipalAmountMayRedeem_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt instrument, redemption price, percentage of principal amount may redeem.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Payments to Acquire Debt Securities, Available-for-Sale</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Purchases of investments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Inventory Disclosure [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption, Period [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsOther_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired, Other Asset, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsOther_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentType_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Type</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentType_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Type</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuroTrancheMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Euro Tranche [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuroTrancheMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Euro tranche.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuroTrancheMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Euro Tranche [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GrossProfit_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Gross profit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GrossProfit_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Gross profit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GrossProfit_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Gross Profit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TypeOfArrangementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Collaborative Arrangement and Arrangement Other than Collaborative [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfRevenueAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cost of revenues:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfRevenueAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cost of Revenue [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ArrangementsAndNonarrangementTransactionsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Collaborative Arrangement and Arrangement Other than Collaborative [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCentralIndexKey_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Central Index Key</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCentralIndexKey_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Central Index Key</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Allowance for doubtful accounts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accounts Receivable, Allowance for Credit Loss, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Current Assets Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other current assets fair value disclosure.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Investments, Debt and Equity Securities [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TranslationAdjustmentForNetInvestmentHedgeNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Outstanding principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TranslationAdjustmentForNetInvestmentHedgeNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivatives used in Net Investment Hedge, Net of Tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TranslationAdjustmentForNetInvestmentHedgeNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Derivatives used in Net Investment Hedge, Net of Tax, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TranslationAdjustmentForNetInvestmentHedgeNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Derivatives used in Net Investment Hedge, Net of Tax, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TranslationAdjustmentForNetInvestmentHedgeNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Aggregate principal amount of net investment hedge</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Decrease in cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventTypeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsequent Event Type [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquityAwardsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Equity Awards [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquityAwardsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity Awards [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EquityAwardsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Equity awards.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IntangibleAssetsNetIncludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Intangible Assets, Net (Including Goodwill), Total</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IntangibleAssetsNetIncludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Intangible Assets, Net (Including Goodwill)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of shares excluded from computation of diluted earnings per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Stock Repurchased and Retired During Period, Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Stock repurchase, shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedAndRetiredDuringPeriodShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock repurchase, shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockParOrStatedValuePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common stock per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockParOrStatedValuePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, Par or Stated Value Per Share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OriginalIssueDiscountPercentageOfPrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Original issue discount percentage of principal amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OriginalIssueDiscountPercentageOfPrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Original Issue Discount Percentage of Principal Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OriginalIssueDiscountPercentageOfPrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Original issue discount percentage of principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TypeOfAdoptionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accounting Standards Update</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TypeOfAdoptionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accounting Standards Update [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Net other comprehensive income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other comprehensive income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Performance Period One</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Tranche One [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BaseRateMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Base Rate [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BaseRateMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Base Rate [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EstimatedAggregatePrincipalAmountPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Estimated aggregate principal amount percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EstimatedAggregatePrincipalAmountPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Estimated Aggregate Principal Amount Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EstimatedAggregatePrincipalAmountPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Estimated aggregate principal amount percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Increase (Decrease) in Other Operating Liabilities, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current and non-current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Other Operating Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives- foreign exchange forward contracts-current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Forward foreign exchange contract derivative liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignCurrencyCashFlowHedgeLiabilityAtFairValue_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Derivative liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JamesASchreinerMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">James A. Schreiner [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JamesASchreinerMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">James A. Schreiner.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JamesASchreinerMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">James A. Schreiner</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instruments [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Disclosure [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedTranslationAdjustmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated Foreign Currency Adjustment Attributable to Parent [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedTranslationAdjustmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Foreign Currency Translation Adjustments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AnyTimePriorToFebruary152029Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Any time Prior to February 15 2029 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AnyTimePriorToFebruary152029Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Any time prior to February 15, 2029.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AnyTimePriorToFebruary152029Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Any Time Prior to February 15, 2029 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueMeasurementInputsDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair Value Measurements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueMeasurementInputsDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeNotionalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Notional amount in EUR/USD</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeNotionalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Notional amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccruedLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accrued Liabilities, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccruedLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Accrued Liabilities, Current, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccruedLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accrued expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfSalesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cost of Revenues [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CostOfSalesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cost of Sales [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_CurrentFiscalYearEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current Fiscal Year End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_CurrentFiscalYearEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Fiscal Year End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt Instrument [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Long-Term Debt Instruments [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFiniteLivedIntangibleAssetsAcquiredAsPartOfBusinessCombinationTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Allocation of Acquired Intangible Assets and Related Estimates of Useful Lives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFiniteLivedIntangibleAssetsAcquiredAsPartOfBusinessCombinationTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Intangible Asset, Acquired, Finite-Lived [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfProductWarrantyLiabilityTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Product Warranty Activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfProductWarrantyLiabilityTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Product Warranty Liability [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AnnualStepDownMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Annual step-down member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AnnualStepDownMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Annual Step-Down [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AnnualStepDownMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Annual Step-Down [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredFinancingCostsInLongTermDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Deferred financing costs in long term debt.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredFinancingCostsInLongTermDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred financing costs in Long Term Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredFinancingCostsInLongTermDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred financing costs in long-term debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LoanVoluntaryPrepaymentAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Loan voluntary prepayment amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LoanVoluntaryPrepaymentAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Loan Voluntary Prepayment Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LoanVoluntaryPrepaymentAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Loan voluntary prepayments amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LoanVoluntaryPrepaymentAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Loan voluntary prepayment amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentQuarterlyReport_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Quarterly Report</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentQuarterlyReport_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Quarterly Report</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired, Other Asset, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfGoodwillAssociatedWithReportableSegmentsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Goodwill Associated with Reportable Segments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfGoodwillAssociatedWithReportableSegmentsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Goodwill Associated with Reportable Segments [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfGoodwillAssociatedWithReportableSegmentsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of goodwill associated with reportable segments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CustomerRelationshipsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Customer Relationships [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CustomerRelationshipsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Customer Relationships [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressStateOrProvince_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, State or Province</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressStateOrProvince_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, State or Province</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">RSU, End of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">RSUs, Beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentLiabilitiesFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentLiabilitiesFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other current liabilities fair value disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentLiabilitiesFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other current liabilities fair value disclosure.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MichelleMMcCarthyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Michelle M McCarthy [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MichelleMMcCarthyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Michelle M McCarthy.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MichelleMMcCarthyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Michelle M. McCarthy</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GuaranteesAndProductWarrantiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Guarantees and Product Warranties [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentInterestRateFairValueHedgeAssetAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Derivatives-interest rate hedge - non-current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentInterestRateFairValueHedgeAssetAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives assets interest rate hedge-non-current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentInterestRateFairValueHedgeAssetAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Current Interest Rate Fair Value Hedge Asset At Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentInterestRateFairValueHedgeAssetAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non current interest rate fair value hedge asset at fair value.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JohnEWilliamsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">John E Williams [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JohnEWilliamsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">John E Williams.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JohnEWilliamsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">John E. Williams</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsGross_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred finance fees, original issue discount and re-pricing fee, gross</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsGross_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Issuance Costs, Gross</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsGross_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Deferred financing fees and original issue discount fees</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Preferred Stock, Shares Outstanding, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Preferred Stock, Shares Outstanding, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Preferred stock, shares outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Preferred Stock, Shares Outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ComprehensiveIncomeNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Comprehensive Income (Loss), Net of Tax, Attributable to Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ComprehensiveIncomeNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total comprehensive income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CappedCallTransactionReductionOrOffsetPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Capped call transaction reduction or offset per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CappedCallTransactionReductionOrOffsetPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Capped Call Transaction Reduction or Offset Per Share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CappedCallTransactionReductionOrOffsetPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Capped call transaction reduction or offset per share.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Incremental Common Shares Attributable to Share-based Payment Arrangements, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Restricted stock units and stock appreciation rights</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Dilutive effect of potential shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_StatementGeographicalAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Geographical</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_StatementGeographicalAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Geographical [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_VacuumSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Vacuum solutions division.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_VacuumSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Vacuum Solutions Division Member</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_VacuumSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">VSD [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_VacuumSolutionsDivisionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Vacuum Solutions Division [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityLenderDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Line of Credit Facility, Lender [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleDebtCappedCallsInitialPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Debt Capped Calls Initial Price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleDebtCappedCallsInitialPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Convertible debt capped calls initial price.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleDebtCappedCallsInitialPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Convertible debt capped calls initial price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfCapitalExpenditureDepreciationAndAmortizationAndAssetsReportableSegmentsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of capital expenditure depreciation and amortization and assets reportable segments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfCapitalExpenditureDepreciationAndAmortizationAndAssetsReportableSegmentsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule Of Capital Expenditure Depreciation And Amortization And Assets Reportable Segments Table [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfCapitalExpenditureDepreciationAndAmortizationAndAssetsReportableSegmentsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Capital Expenditures, Depreciation and Amortization Expense of Intangible Assets by Reportable Segment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Pre-tax Effect of Stock-Based Compensation Expense Included in Company's Condensed Consolidated Statements of Operations and Comprehensive Income (Loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentConversionRateShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument conversion rate shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentConversionRateShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument Conversion Rate Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentConversionRateShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt instrument conversion rate shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestAndOtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestAndOtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest and Other Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestAndOtherIncome_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Interest income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Subsequent Event [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsequent Event [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CashEquivalentsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CashEquivalentsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Equivalents Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CashEquivalentsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cash equivalents fair value disclosure.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Maturity, Remainder of Fiscal Year</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2026 (remaining)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PatentsTrademarksTradeNamesAndOtherMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Patents Trademarks Trade Names And Other [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PatentsTrademarksTradeNamesAndOtherMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Patents trademarks trade names and other.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PatentsTrademarksTradeNamesAndOtherMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Patents, Trademarks, Trade Names and Other [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAcquiredAsPartOfBusinessCombinationTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Intangible Asset, Acquired, Finite-Lived [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAcquiredAsPartOfBusinessCombinationTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Finite Lived Intangible Assets Acquired As Part Of Business Combination [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherAssetsNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Other assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherAssetsNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Assets Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherAssetsNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Assets, Noncurrent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherAssetsNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total segment assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Segment assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Antidilutive Securities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Antidilutive Securities [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentLeaseLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentLeaseLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current Lease Liability</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentLeaseLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Present value of lessee's discounted obligation for lease payments from operating and financing lease, classified as noncurrent.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoInterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Derivative instruments gain loss reclassified from accumulated Oci into interest expense.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoInterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Instruments Gain Loss Reclassified From Accumulated Oci Into Interest Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoInterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net gains (losses) reclassified from accumulated OCI into interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Expense, Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Interest Expense, Debt, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">AOCI Attributable to Parent [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accumulated Other Comprehensive (Loss) Income [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Accumulated Other Comprehensive Income (Loss) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ChangesInValueOfFinancialInstrumentsDesignatedAsCashFlowHedgesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Changes in Value of Financial Instruments Designated as Cash Flow Hedges [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ChangesInValueOfFinancialInstrumentsDesignatedAsCashFlowHedgesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Changes in value of financial instruments designated as cash flow hedges.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ChangesInValueOfFinancialInstrumentsDesignatedAsCashFlowHedgesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Changes in Value of Financial Instruments Designated as Cash Flow Hedges [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Liability</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Finite-Lived Intangible Assets, Major Class Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Assets, Major Class Name [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BankersAcceptanceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Banker's Acceptance Drafts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BankersAcceptanceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Bankers' Acceptance Drafts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BankersAcceptanceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Bankers Acceptance [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReportingUnitGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Reporting unit goodwill.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReportingUnitGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reporting Unit Goodwill</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReportingUnitGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Remaining Goodwill</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReportingUnitGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance, Goodwill Gross Carrying Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Impairment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Impairment charge, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Impairment charge</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Impairment of goodwill, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Impairment charge</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Thereafter</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Asset, Expected Amortization, after Year Five</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CompletedTechnologyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Completed technology.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CompletedTechnologyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Completed Technology [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleDebtCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Convertible Notes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleDebtCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Debt, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Preferred Stock, Value, Issued, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Preferred Stock, Value, Issued, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Preferred Stock, Value, Issued, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Preferred Stock, Value, Issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Preferred stock, $0.01 par value, 2 shares authorized; no shares issued and outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Consideration Transferred, Equity Interest, Share Issued, Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Value of MKS shares issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Intangible assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired, Identifiable Intangible Asset, Finite-Lived</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SellingGeneralAndAdministrativeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Selling, General and Administrative Expense, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SellingGeneralAndAdministrativeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Selling, general and administrative</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SellingGeneralAndAdministrativeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Selling, General and Administrative Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentMaturityDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Maturity Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentMaturityDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Maturity date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Flow Hedge Gain (Loss) to be Reclassified within 12 Months</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash flow hedge to be reclassified in 12 months</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentConvertibleConversionPricePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument conversion price percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentConvertibleConversionPricePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument Convertible Conversion Price Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentConvertibleConversionPricePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt instrument convertible conversion price percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_MinimumMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Minimum [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_MinimumMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Minimum [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted Average Grant Date Fair Value, Granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ClassOfTreasuryStockTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Class of Treasury Stock [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AssetsCurrentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current assets:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AssetsCurrentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Assets, Current [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseOther_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Expense, Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseOther_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other interest expense, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AmortizationOfIntangibleAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Amortization of Intangible Assets, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AmortizationOfIntangibleAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amortization of intangible assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AmortizationOfIntangibleAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amortization of Intangible Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueInputsLevel3Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Significant Unobservable Inputs (Level 3) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueInputsLevel3Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value, Inputs, Level 3 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationIntegrationReversalOfAcquisitionAndIntegrationCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination Integration Reversal Of Acquisition And Integration Costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationIntegrationReversalOfAcquisitionAndIntegrationCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Business combination integration reversal of acquisition and integration costs.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationIntegrationReversalOfAcquisitionAndIntegrationCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Acquisition and integration costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IntangibleAssetsFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Intangible assets fair value.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IntangibleAssetsFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Intangible Assets Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IntangibleAssetsFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Intangible assets fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentReportingAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Reporting [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total assets acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired, Asset</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Fair Value of Assets and Liabilities Measured on Recurring Basis</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Unrealized (Loss) Gain on Investments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentCurrentConvertibleConversionPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument current conversion rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentCurrentConvertibleConversionPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Current Convertible, Conversion Price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentCurrentConvertibleConversionPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt instrument, current convertible, conversion price.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesCurrentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current liabilities:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LiabilitiesCurrentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities, Current [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Products [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Product [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock repurchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Stock Repurchased and Retired During Period, Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedAndRetiredDuringPeriodValue_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Stock repurchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherCurrentLiabilitiesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Other Current Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherCurrentLiabilitiesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Current Liabilities [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationCashPaidForOutstandingShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash paid for outstanding shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationCashPaidForOutstandingShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination Cash Paid For Outstanding Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationCashPaidForOutstandingShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Business combination cash paid for outstanding shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_WeightedAverageNumberOfDilutedShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Number Of Diluted Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_WeightedAverageNumberOfDilutedShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average number of diluted shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_WeightedAverageNumberOfDilutedShares_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Shares used in net income per common share - diluted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccountsReceivableNetCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Accounts receivable, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccountsReceivableNetCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Accounts Receivable, after Allowance for Credit Loss, Current, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccountsReceivableNetCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accounts Receivable, after Allowance for Credit Loss, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccountsReceivableNetCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade accounts receivable, net of allowance for doubtful accounts of $6 and $5 at June 30, 2026 and December 31, 2025, respectively</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsNoncurrentGross_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Issuance Cost, Gross, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsNoncurrentGross_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Debt issuance costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsNoncurrentGross_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt issuance costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReportingUnitAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reporting Unit [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommitmentsAndContingencies_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commitments and contingencies (Note 17)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommitmentsAndContingencies_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commitments and Contingencies</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCountriesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other countries.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCountriesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other countries [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCountriesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">RSUs, Weighted Average Grant Date Fair Value, Beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">RSUs, Weighted Average Grant Date Fair Value, End of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net issuance under stock-based plans, Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Shares Issued, Shares, Share-based Payment Arrangement, after Forfeiture, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BacklogMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Backlog [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BacklogMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Backlog [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BacklogMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Backlog [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryWorkInProcessNetOfReserves_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Work-in-process</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryWorkInProcessNetOfReserves_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Inventory, Work in Process, Net of Reserves</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument, interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Basis Spread on Variable Rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ScenarioForecastMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Forecast [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ScenarioForecastMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Scenario Forecast [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermBorrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Short-term Debt, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermBorrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Short term debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermBorrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Short-term debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermBorrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-Term Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockNoParValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common stock, par value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockNoParValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, No Par Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfGoodwillTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Goodwill</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfGoodwillTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Goodwill [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentReportingAssetReconcilingItemLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segment Reporting, Asset Reconciling Item [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentReportingAssetReconcilingItemLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Reporting, Asset Reconciling Item [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuriborRateFloorMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">EURIBOR rate floor member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuriborRateFloorMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">EURIBOR Rate Floor [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EuriborRateFloorMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">EURIBOR Rate Floor [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncreaseDecreaseCurrentAndNonCurrentAccruedCompensation_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Current and non-current accrued compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncreaseDecreaseCurrentAndNonCurrentAccruedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current and non-current accrued compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncreaseDecreaseCurrentAndNonCurrentAccruedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase Decrease Current And Non Current Accrued Compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncreaseDecreaseCurrentAndNonCurrentAccruedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase decrease current and non current accrued compensation.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyLiabilityLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Product Warranty Liability [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyLiabilityLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Product Warranty Liability [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsNoncurrentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Debt Issuance Costs, Noncurrent, Net, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsNoncurrentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred financing fees, original issuance discount and repricing fees</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsNoncurrentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Issuance Costs, Noncurrent, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredFinanceCostsNoncurrentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Debt issuance costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElizabethAMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Elizabeth A [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElizabethAMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Elizabeth A [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ElizabethAMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Elizabeth A</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Maturity, Year Two</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2028</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ExpenseOfRestructuringActivitiesAndOtherTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Restructuring</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ExpenseOfRestructuringActivitiesAndOtherTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expense of restructuring activities and other.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ExpenseOfRestructuringActivitiesAndOtherTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expense Of Restructuring Activities And Other [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ExpenseOfRestructuringActivitiesAndOtherTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Restructuring and Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Effect of exchange rate changes on cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BankTimeDepositsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Time Deposits [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BankTimeDepositsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Bank Time Deposits [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Net Income (Loss), Including Portion Attributable to Noncontrolling Interest</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Net income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Less: Cash and cash equivalents acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReconciliationOfAssetsFromSegmentToConsolidatedTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reconciliation of Assets from Segment to Consolidated [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReconciliationOfAssetsFromSegmentToConsolidatedTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Reconciles Total Segment Assets to Total Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Weighted Average Number of Shares Outstanding, Basic, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Basic</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Number of Shares Outstanding, Basic</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Shares used in net income per share - basic</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_StatementScenarioAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Scenario [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IsraeliPensionAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Israeli Pension Assets [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IsraeliPensionAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Israeli Pension Assets [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IsraeliPensionAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Israeli Pension Assets [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementBusinessSegmentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementBusinessSegmentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segments [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PropertyPlantAndEquipmentTypeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Lived Tangible Asset [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfEarningsPerShareTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Earnings Per Share [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfEarningsPerShareTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule Of Earnings Per Share [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfEarningsPerShareTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule Of Earnings Per Share [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_O2024Q4DividendsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">O 2024 Q4 Dividends.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_O2024Q4DividendsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">O 2024 Q4 Dividends [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrualNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Long-term product warranties</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrualNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Product Warranty Accrual, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfShortTermDebtTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Short-Term Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfShortTermDebtTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Short-Term Debt [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Subsequent Events</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsequent Events [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryRawMaterialsNetOfReserves_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Raw materials</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryRawMaterialsNetOfReserves_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Inventory, Raw Materials, Net of Reserves</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MutualFundsAndExchangeTradedFundsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Mutual Funds and Exchange Traded Funds [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MutualFundsAndExchangeTradedFundsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Mutual Funds And Exchange Traded Funds [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MutualFundsAndExchangeTradedFundsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Mutual funds and exchange traded funds member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Long-term Debt, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Long term debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Long-term debt, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock-based compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">APIC, Share-Based Payment Arrangement, Increase for Cost Recognition</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentInterestRateTerms_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument, interest rate terms</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentInterestRateTerms_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Interest Rate Terms</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_VariableRateDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Variable Rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_VariableRateDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Variable Rate [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockholdersEquity_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total stockholders&#8217; equity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockholdersEquity_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity, Attributable to Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockholdersEquity_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockholdersEquity_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockParOrStatedValuePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Preferred stock, par value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockParOrStatedValuePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Preferred Stock, Par or Stated Value Per Share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfOtherDerivativesNotDesignatedAsHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivatives Not Designated as Hedging Instruments [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfOtherDerivativesNotDesignatedAsHedgingInstrumentsStatementsOfFinancialPerformanceAndFinancialPositionLocationTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Net Gains (Losses) on Derivatives Not Designated as Hedging Instruments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Interest Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Income and Interest Expense Disclosure [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementOfStockholdersEquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of Stockholders' Equity [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AtotechMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Atotech member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AtotechMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Atotech [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AtotechMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Atotech [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheTwoMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Tranche Two [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationAwardTrancheTwoMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Performance Period Two</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_TypeOfRestructuringDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Type of Restructuring [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RestructuringExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Charged to expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RestructuringExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Restructuring expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RestructuringExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Restructuring expense.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2026 (remaining)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Property, Plant, and Equipment, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired, Property, Plant, and Equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermSofrRatePlusApplicableCreditSpreadAdjustmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Term SOFR rate (plus applicable credit spread adjustment) member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermSofrRatePlusApplicableCreditSpreadAdjustmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Term SOFR Rate (Plus Applicable Credit Spread Adjustment) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermSofrRatePlusApplicableCreditSpreadAdjustmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Term SOFR Rate (Plus Applicable Credit Spread Adjustment) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OciBeforeReclassificationsNetOfTaxAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">OCI, before Reclassifications, Net of Tax, Attributable to Parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OciBeforeReclassificationsNetOfTaxAttributableToParent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other comprehensive income (loss) before reclassifications</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsPayableDateDeclaredDayMonthAndYear_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Dividend declared date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsPayableDateDeclaredDayMonthAndYear_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Dividends Payable, Date Declared</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NewTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">New Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NewTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">New Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NewTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">New term loan facility.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_US_lbl" xlink:role="http://www.xbrl.org/2003/role/label">UNITED STATES</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_US_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">United States [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated Defined Benefit Plans Adjustment Attributable to Parent [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Unrecognized Pension Gain (Loss) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoCostOfRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net gains (losses) reclassified from accumulated OCI into cost of revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoCostOfRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Derivative instruments, gain loss reclassified from accumulated ocIi into cost of revenues.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoCostOfRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Instruments, Gain (Loss) Reclassified from Accumulated OCI into Cost of Revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt Instrument, Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Name [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherAssetsCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherAssetsCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Assets, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Maturity, Year Four</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2030</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionEffectiveDateOfAcquisition1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Effective Date of Acquisition</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionEffectiveDateOfAcquisition1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Business acquisition date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Acquired Finite Lived Intangible Assets [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Intangible Asset, Acquired, Finite-Lived [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfRestructuringAndOtherCostTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of restructuring and other cost.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfRestructuringAndOtherCostTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule Of Restructuring And Other Cost [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfRestructuringAndOtherCostTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Restructuring And Other Cost [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivative Instruments and Hedging Activities Disclosure [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Instruments and Hedging Activities Disclosure [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentReportingCodmIndividualTitleAndPositionOrGroupOrCommitteeNameExtensibleEnumeration_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InProcessResearchAndDevelopmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">IPR&amp;D [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InProcessResearchAndDevelopmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">In-process Research and Development [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InProcessResearchAndDevelopmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">In Process Research and Development [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermDebtRefinancedAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt refinanced amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermDebtRefinancedAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-Term Debt, Refinanced, Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOtherOperatingAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Increase (Decrease) in Other Operating Assets, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOtherOperatingAssets_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other current and non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOtherOperatingAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Other Operating Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Expense, Operating and Nonoperating</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoansUnderNewTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Term loans under new term loan facility member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoansUnderNewTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Term Loans under New Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoansUnderNewTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Term Loans under New Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CreditFacilityAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Credit Facility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CreditFacilityAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Credit Facility [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentGrossProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segment gross profit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentGrossProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Gross Profit (Loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentGrossProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Segment gross profit (loss).</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income taxes payable</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInIncomeTaxesPayableNetOfIncomeTaxesReceivable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Income Taxes Payable, Net of Income Taxes Receivable</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OriginalIssueDiscountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Original Issue Discount [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OriginalIssueDiscountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Original Issue Discount [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OriginalIssueDiscountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Original issue discount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduledQuarterlyPaymentsPercentageOfOriginalPrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Scheduled quarterly payments percentage of original principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduledQuarterlyPaymentsPercentageOfOriginalPrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Scheduled quarterly payments percentage of original principal amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduledQuarterlyPaymentsPercentageOfOriginalPrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Scheduled Quarterly Payments Percentage of Original Principal Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ProceedsFromPaymentsForEmployeeStockAwards_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds From Payments For Employee Stock Awards</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ProceedsFromPaymentsForEmployeeStockAwards_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Proceeds from payments for employee stock awards.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ProceedsFromPaymentsForEmployeeStockAwards_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net payments related to employee stock awards</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument Redemption [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Redemption Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalUsdTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Incremental USD Tranche B.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalUsdTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Incremental USD Tranche B [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalUsdTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Incremental USD Tranche B Loans [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressCityOrTown_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, City or Town</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityAddressCityOrTown_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, City or Town</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GoodwillAndIntangibleAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Goodwill And Intangible Assets [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GoodwillAndIntangibleAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill And Intangible Assets [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GoodwillAndIntangibleAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Goodwill and intangible assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedDuringPeriodShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock repurchase, shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedDuringPeriodShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Stock Repurchased During Period, Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedDuringPeriodShares_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Stock repurchase, shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NumberOfReportableSegments_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of reportable segments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NumberOfReportableSegments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of Reportable Segments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_SecurityExchangeName_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Security Exchange Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_SecurityExchangeName_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Security Exchange Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NumberOfInterestRateDerivativesHeld_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of Interest Rate Derivatives Held</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NumberOfInterestRateDerivativesHeld_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number Of USD LIBOR based swaps</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GovernmentAssistanceAssetDecreaseCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Government Assistance, Asset, Decrease, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GovernmentAssistanceAssetDecreaseCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Investment tax credits in other current assets with a corresponding reduction to the carrying amounts of the qualifying manufacturing assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CreditFacilityDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Credit Facility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CreditFacilityDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Credit Facility [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Indefinite-lived Intangible Assets (Excluding Goodwill), Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Indefinite-lived Intangible Assets (Excluding Goodwill), Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Indefinite-lived Intangible Assets (Excluding Goodwill), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Indefinite-Lived Intangible Assets (Excluding Goodwill)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Un-amortized intangible assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionDateOfAcquisitionAgreement1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Date of Acquisition Agreement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionDateOfAcquisitionAgreement1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Credit agreement date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentCarryingAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Term Loan Facility, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentCarryingAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Gross</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtIssuanceCostsAmortizationPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt issuance costs, amortization period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtIssuanceCostsAmortizationPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt issuance costs, amortization period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtWeightedAverageInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt, Weighted Average Interest Rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtWeightedAverageInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Income before income taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CompensationRelatedCostsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Compensation Related Costs [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Net (Gains) on Derivatives Designated as Cash Flow Hedging Instruments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Cash Flow Hedges Included in Accumulated Other Comprehensive Income (Loss) [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfCashFlowHedgesIncludedInAccumulatedOtherComprehensiveIncomeLossTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Summary of Net (Losses) Gains on Derivatives Designated as Cash Flow Hedging Instruments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MeasurementInputTypeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Measurement Input Type [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AntidilutiveSecuritiesNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Antidilutive Securities, Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AntidilutiveSecuritiesNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Antidilutive Securities, Name [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalTrancheBLoansFourthAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Incremental tranche B loans fourth amendment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalTrancheBLoansFourthAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Incremental Tranche B Loans Fourth Amendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalTrancheBLoansFourthAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Incremental Tranche B Loans Fourth Amendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockholdersEquityNoteAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Stockholders' Equity Note [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryNet_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryNet_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Inventories</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryNet_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Inventories</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InventoryNet_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Inventory, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JacquelineFMoloneyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Jacqueline F Moloney [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JacquelineFMoloneyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Jacqueline F Moloney.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JacquelineFMoloneyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Jacqueline F. Moloney</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_RangeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Statistical Measurement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_RangeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statistical Measurement [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AssetsCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AssetsCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Assets, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AllocatedShareBasedCompensationExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AllocatedShareBasedCompensationExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Total stock-based compensation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentPeriodEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Period End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentPeriodEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Period End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtSecuritiesAvailableForSaleAndHeldToMaturityAmortizedCostAfterAllowanceForCreditLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Available-for-sale securities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtSecuritiesAvailableForSaleAndHeldToMaturityAmortizedCostAfterAllowanceForCreditLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Investments, Cost</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtSecuritiesAvailableForSaleAndHeldToMaturityAmortizedCostAfterAllowanceForCreditLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Available-for-sale investments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtSecuritiesAvailableForSaleAndHeldToMaturityAmortizedCostAfterAllowanceForCreditLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Investments, Cost</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueMeasurementsFairValueHierarchyDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair Value Hierarchy and NAV</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueMeasurementsFairValueHierarchyDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value Hierarchy and NAV [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Accumulated Impairment Charges</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Impairment of Intangible Assets, Indefinite-Lived (Excluding Goodwill)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReportingUnitPercentageOfFairValueInExcessOfCarryingAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Percentage of fair value of reporting unit in excess of carrying amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReportingUnitPercentageOfFairValueInExcessOfCarryingAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reporting Unit, Percentage of Fair Value in Excess of Carrying Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalTrancheBLoansSecondAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Incremental tranche B loans second amendment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalTrancheBLoansSecondAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Incremental Tranche B Loans Second Amendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementOfFinancialPositionAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of Financial Position [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestrictedStockUnitsRSUMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Restricted Stock Units (RSUs) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestrictedStockUnitsRSUMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Restricted Stock Units (RSUs) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RestrictedStockUnitsRSUMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Restricted Stock Units [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_VestingAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Vesting</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_VestingAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Vesting [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other comprehensive (loss), net of tax:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Other comprehensive income (loss), net of tax:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IndentureAndTheNotesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Indenture and the Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IndentureAndTheNotesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Indenture and the Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other comprehensive income (loss) net investment hedge gain (loss) net of tax.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other comprehensive income (loss), net investment hedge, gain (loss), net of tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Change in net investment hedges</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GroupInsuranceContractsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Group Insurance Contracts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GroupInsuranceContractsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Group Insurance Contracts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GroupInsuranceContractsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Group insurance contracts.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_Year5Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Year 5 member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_Year5Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Year 5 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_Year5Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Year 5 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NondesignatedMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Not Designated as Hedging Instrument [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NondesignatedMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives not Designated as Hedging Instruments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalBorrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Incremental borrowings.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalBorrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Incremental Borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalBorrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Incremental borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Liabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Liabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherNonCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherNonCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Non Current Assets Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherNonCurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other non current assets fair value disclosure.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_KR_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">KR</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_KR_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">South Korea [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_KR_lbl" xlink:role="http://www.xbrl.org/2003/role/label">KOREA, REPUBLIC OF</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeLiabilityStatementOfFinancialPositionExtensibleEnumeration_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivative Liability, Statement of Financial Position [Extensible Enumeration]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeLiabilityStatementOfFinancialPositionExtensibleEnumeration_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Liability, Statement of Financial Position [Extensible Enumeration]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsGainLossLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivative Instruments, Gain (Loss) [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DerivativeInstrumentsGainLossLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivative Instruments, Gain (Loss) [Line Items]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ForeignExchangeForwardMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Foreign Exchange Contracts [Member]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiabilityCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred revenue and customer advances</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiabilityCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contract with Customer, Liability, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeSeveranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Severance Costs [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeSeveranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Employee Severance [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AtotechLimitedMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Atotech Limited [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AtotechLimitedMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Atotech Limited [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AtotechLimitedMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Atotech Limited.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AtotechLimitedMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Atotech [Member]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AccumulatedOtherComprehensiveIncomeLossChangeInNetInvestmentHedgeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Accumulated other comprehensive income loss change in net investment hedge.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AccumulatedOtherComprehensiveIncomeLossChangeInNetInvestmentHedgeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Change in Net Investment Hedge [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total liabilities assumed</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Liability Assumed, Liability</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NatureOfTradingArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Nature of Trading Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NatureOfTradingArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Nature of trading arrangement.</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Common Stock, Shares, Outstanding, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common stock, shares outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, Shares, Outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingLeaseLiabilityCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingLeaseLiabilityCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Operating Lease, Liability, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Dividends [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentTransitionReport_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Transition Report</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentTransitionReport_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Transition Report</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermInvestments_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Short-term Investments, Total</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermInvestments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-Term Investments</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherNonCurrentLiabilitiesFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other non current liabilities fair value disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherNonCurrentLiabilitiesFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other non current liabilities fair value disclosure.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ResearchAndDevelopmentExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Research and Development Expense, Total</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LesseeOperatingLeasesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Leases</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsForRepurchaseOfCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Repurchase of common stock</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrealizedGainLossOnDerivatives_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unrealized Gain (Loss) on Derivatives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrealizedGainLossOnDerivatives_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Unrealized (gain) loss on foreign currency and derivative instruments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementOfCashFlowsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of Cash Flows [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CompletedTechnologyRightsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Completed Technology [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CompletedTechnologyRightsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Completed Technology Rights [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CompletedTechnologyRightsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Completed Technology Rights [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ChangeInContractWithCustomerLiabilityTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Change In Contract With Customer Liability [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ChangeInContractWithCustomerLiabilityTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Change In Contract With Customer Liability [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ChangeInContractWithCustomerLiabilityTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Change in Contract with Customer, Liability [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Acquisition of business, net of cash acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total purchase price, net of cash and cash equivalents acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total purchase price, net of cash and cash equivalents acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Payments to Acquire Businesses, Net of Cash Acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ReconciliationOfAssetsFromSegmentToConsolidatedTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Reconciliation Of Assets From Segment To Consolidated [Table]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestRateSwapMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Rate Swap [Member]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share [Text Block]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Shares, Issued</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentConvertibleApplicableConversionPrice_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt instrument, convertible, applicable conversion price.</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetIncomeLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net income</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DerivativeAndHedgingTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Derivative And Hedging [Table]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LineOfCreditFacilityMinimumAdditionalBorrowingCapacity_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Line of credit facility minimum additional borrowing capacity.</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_O2025Q3DividendsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">O 2025 Q3 Dividends.</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MoneyMarketFundsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Money Market Funds [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_MoneyMarketFundsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Money Market Funds [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InterestRateHegesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Interest rate heges.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InterestRateHegesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Rate Heges [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InterestRateHegesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest Rate Hedges [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeTaxDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income Taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeTaxDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income Tax Disclosure [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OccurrenceOfAChangeOfControlTriggeringEventMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Occurrence of a Change of Control Triggering Event [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OccurrenceOfAChangeOfControlTriggeringEventMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Occurrence of a change of control triggering event.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherLiabilitiesNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Liabilities, Noncurrent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherLiabilitiesNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other non-current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherLiabilitiesNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Liabilities, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption, Period [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Changes in operating assets and liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeTaxDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income Tax Disclosure [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value, Recurring and Nonrecurring [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Acquisition</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amount of gross unrecognized tax benefits excluding interest and penalties</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Unrecognized Tax Benefits, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Unrecognized Tax Benefits, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unrecognized Tax Benefits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdditionalPaidInCapitalMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Additional Paid-In Capital [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AdditionalPaidInCapitalMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Additional Paid-in Capital [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LoansIssuanceDiscountRate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Loans issuance discount rate.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LoansIssuanceDiscountRate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Loans Issuance Discount Rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_LoansIssuanceDiscountRate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Loans issuance discount rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleSeniorNotesDue2030Member_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Convertible Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleSeniorNotesDue2030Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Convertible Senior Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleSeniorNotesDue2030Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Senior Notes Due 2030 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ConvertibleSeniorNotesDue2030Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Convertible senior notes due 2030.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueMeasurementFrequencyDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Measurement Frequency</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueMeasurementFrequencyDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Measurement Frequency [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_StockRepurchaseProgramAuthorizedAmount1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common stock, value of shares authorized to repurchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_StockRepurchaseProgramAuthorizedAmount1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share Repurchase Program, Authorized, Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeStatementLocationAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income Statement Location</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeStatementLocationAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of Income Location, Balance [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">New Accounting Pronouncements or Change in Accounting Principle [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">New Accounting Pronouncements or Change in Accounting Principle [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_TradingSymbol_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trading Symbol</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_TradingSymbol_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trading Symbol</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RestructuringCostAndOtherCostLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Restructuring cost and other cost.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RestructuringCostAndOtherCostLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Restructuring Cost And Other Cost [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RestructuringCostAndOtherCostLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Restructuring Cost and Other Cost [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Finite Lived Intangible Assets [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Intangible Asset, Finite-Lived [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InterestRateHedgeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Rate Hedge [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_InterestRateHedgeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Interest rate hedge.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentInterestRateFairValueHedgeLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Current Interest Rate Fair Value Hedge Liabilities At Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentInterestRateFairValueHedgeLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non- current interest rate fair value hedge liabilities at fair value.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NonCurrentInterestRateFairValueHedgeLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Derivatives - interest rate hedge - non-current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodThreeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption, Period Three [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodThreeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2031 and Thereafter [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodThreeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Upon the Occurrence of Change of Control Triggering Event [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventTypeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsequent Event Type [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CustomerAdvancesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Customer Advances [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CustomerAdvancesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Customer Advances [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CustomerAdvancesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Customer Advances [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Finite-Lived Intangible Assets [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Intangible Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeRelatedLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accrued compensation and other employee-related obligations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeRelatedLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Employee-related Liabilities, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeRelatedLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Employee-related Liabilities, Current, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_TW_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Taiwan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_TW_lbl" xlink:role="http://www.xbrl.org/2003/role/label">TAIWAN</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash flows from financing activities:</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueMeasurementsRecurringMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value, Recurring [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AcquisitionDateLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Acquisition Date [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AcquisitionDateLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Acquisition Date [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AcquisitionDateLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Acquisition Date [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillAndIntangibleAssetImpairment_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Goodwill and Intangible Asset Impairment, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillAndIntangibleAssetImpairment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill and Intangible Asset Impairment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillAndIntangibleAssetImpairment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Goodwill and intangible asset impairments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementEquityComponentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Additional Paid-In Capital [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StatementEquityComponentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity Components [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ContractWithCustomerAmountOfDeferredRevenueAndCustomerAdvancesRecognized_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Amount of deferred revenue and customer advances recognized in income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ContractWithCustomerAmountOfDeferredRevenueAndCustomerAdvancesRecognized_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contract With Customer Amount Of Deferred Revenue And Customer Advances Recognized</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ContractWithCustomerAmountOfDeferredRevenueAndCustomerAdvancesRecognized_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Contract with customer amount of deferred revenue and customer advances recognized</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RepurchaseOfDebtPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Repurchase of principal amount percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RepurchaseOfDebtPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Repurchase Of Debt Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_RepurchaseOfDebtPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Repurchase of debt percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NonoperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Nonoperating Income (Expense), Total</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EquityComponentDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity Component [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EquityComponentDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Equity Component</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueByAssetClassAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Asset Class</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueByAssetClassAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Asset Class [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill and Intangible Assets Disclosure [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SpecialtyIndustrialMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Specialty industrial.</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrual_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Standard and Extended Product Warranty Accrual, Total</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrual_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Standard and Extended Product Warranty Accrual</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Estimated Fair Value of Assets Acquired and Liabilities Assumed</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Recognized Asset Acquired and Liability Assumed [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Assets Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current assets fair value disclosure.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Business Acquisition</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermNotesPayable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Notes Payable, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermNotesPayable_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Notes Payable, Noncurrent, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermNotesPayable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2034 Notes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MinimumPercentageOfEarningsBeforeInterestTaxesDepreciationAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Minimum percentage of consolidated EBITDA</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MinimumPercentageOfEarningsBeforeInterestTaxesDepreciationAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Minimum Percentage Of Earnings Before Interest Taxes Depreciation And Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MinimumPercentageOfEarningsBeforeInterestTaxesDepreciationAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Minimum percentage of earnings before interest taxes depreciation and amortization.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DepreciationAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Depreciation, Depletion and Amortization, Nonproduction, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DepreciationAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Depreciation and amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DepreciationAndAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Depreciation, Depletion and Amortization, Nonproduction</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfBusinessCombinationAcquireeRevenueAndIncomeBeforeIncomeTaxesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of business combination acquiree revenue and income before income taxes.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfBusinessCombinationAcquireeRevenueAndIncomeBeforeIncomeTaxesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule Of Business Combination Acquiree Revenue And Income Before Income Taxes [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfBusinessCombinationAcquireeRevenueAndIncomeBeforeIncomeTaxesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Revenue and Net Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBFirstAmmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">USD Tranche B First Ammendment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheBFirstAmmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">USD Tranche B First Ammendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_MaximumMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Maximum [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_MaximumMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Maximum [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendPayableDateToBePaidDayMonthAndYear_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Dividend to be paid date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendPayableDateToBePaidDayMonthAndYear_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Dividends Payable, Date to be Paid</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DesignatedAsHedgingInstrumentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Designated as Hedging Instrument [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DesignatedAsHedgingInstrumentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives Designated as Hedging Instruments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_RangeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Statistical Measurement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_RangeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statistical Measurement [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MinimumPercentageOfIncomeTaxPaymentNetOfRefundsReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Minimum percentage of income tax payment net of refunds received.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MinimumPercentageOfIncomeTaxPaymentNetOfRefundsReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Minimum percentage of income tax payment net of refunds received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_MinimumPercentageOfIncomeTaxPaymentNetOfRefundsReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Minimum percentage of income tax payment net of refunds received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiabilityNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Non-current deferred revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiabilityNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Long-term deferred revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerLiabilityNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contract with Customer, Liability, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amortization expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Assets, Accumulated Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Finite-Lived Intangible Assets, Accumulated Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Accumulated Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Common Stock, Value, Issued, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Common Stock, Value, Issued, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Common Stock, Value, Issued, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, Value, Issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Common stock, no par value, 200 shares authorized; 67.6 and 67.2 shares issued and outstanding at June 30, 2026 and December 31, 2025, respectively</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalTrancheBLoansMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Incremental Tranche B Loans.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalTrancheBLoansMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Incremental Tranche B Loans [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DividendsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Dividends [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredRevenueMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred Revenue [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredRevenueMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred Revenue [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredRevenueMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Deferred Revenue [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SecuredOvernightFinancingRateSofrMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Secured Overnight Financing Rate (SOFR) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SecuredOvernightFinancingRateSofrMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">SOFR Borrowings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ComprehensiveIncomeNetOfTaxAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ComprehensiveIncomeNetOfTaxAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Comprehensive income (loss) (net of tax):</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AmortizationOfFinancingCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amortization of debt issuance costs as interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AmortizationOfFinancingCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amortization of Debt Issuance Costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalRevolvingCommitmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Incremental Revolving Commitments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_IncrementalRevolvingCommitmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Incremental Revolving Commitments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SixthAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Sixth Amendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SixthAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Sixth Amendment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SixthAmendmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Sixth Amendment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Estimated Amortization Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BorrowingsUnderNewRevolvingFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Borrowings under new revolving facility member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BorrowingsUnderNewRevolvingFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Borrowings under New Revolving Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BorrowingsUnderNewRevolvingFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Borrowings under New Revolving Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentInterestRateFairValueHedgeLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Interest Rate Fair Value Hedge Liabilities At Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentInterestRateFairValueHedgeLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current interest rate fair value hedge liabilities at fair value.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CurrentInterestRateFairValueHedgeLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives - interest rate hedge - current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesAuthorized_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Preferred stock, shares authorized</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PreferredStockSharesAuthorized_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Preferred Stock, Shares Authorized</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Finite-Lived Intangible Assets by Major Class</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Assets by Major Class [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OutstandingDebtUnderInvestmentHedges_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Outstanding debt under investment hedges.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OutstandingDebtUnderInvestmentHedges_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Outstanding Debt Under Investment Hedges</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OutstandingDebtUnderInvestmentHedges_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Outstanding amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReductionToInterestExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Reduction to interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReductionToInterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reduction to interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ReductionToInterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Reduction to interest expense.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Lender Name [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfAllocationOfPurchasePriceTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Purchase Price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfAllocationOfPurchasePriceTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule Of Allocation Of Purchase Price Table [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_ScheduleOfAllocationOfPurchasePriceTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of allocation of purchase price.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RepaymentsOfConvertibleDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Repayments of Convertible Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RepaymentsOfConvertibleDebt_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Purchase of capped calls related to Convertible Notes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfConsecutiveTradingDays_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of consecutive trading days</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfConsecutiveTradingDays_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Consecutive Trading Days</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_NumberOfConsecutiveTradingDays_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of consecutive trading days.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenueFromContractWithCustomerTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revenue from Contracts with Customers</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenueFromContractWithCustomerTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue from Contract with Customer [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule Of Business Acquisitions By Acquisition [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityRegistrantName_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Entity Registrant Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityRegistrantName_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Registrant Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accrued interest on unrecognized tax benefits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Disclosure [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedCompensationCost_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Settlement of accelerated share-based awards</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedCompensationCost_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Accelerated Cost</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentPeriodicPaymentPrincipal_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Scheduled quarterly payments amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentPeriodicPaymentPrincipal_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Periodic Payment, Principal</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Asset, Expected Amortization, Year Two</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2028</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNonoperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other Nonoperating Income (Expense), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNonoperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Nonoperating Income (Expense)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNonoperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other expense (income), net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherNonoperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other (income) expense, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated Other Comprehensive Income (Loss) [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SubsequentEventsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsequent Events [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Asset, Expected Amortization, Year Three</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2029</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeTaxExpenseBenefit_lbl" xlink:role="http://www.xbrl.org/2003/role/label">(Benefit) provision for income taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeTaxExpenseBenefit_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Income Tax Expense (Benefit), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeTaxExpenseBenefit_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Provision (benefit) for income taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeTaxExpenseBenefit_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for income taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueByMeasurementFrequencyAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Measurement Frequency</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueByMeasurementFrequencyAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Measurement Frequency [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockDividendsPerShareCashPaid_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash dividends per common share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockDividendsPerShareCashPaid_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, Dividends, Per Share, Cash Paid</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredCompensationPlanAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred compensation plan assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredCompensationPlanAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred Compensation Plan Assets Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DeferredCompensationPlanAssetsFairValueDisclosure_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Deferred Compensation Plan Assets Fair Value Disclosure</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedDuringPeriodValue_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Stock repurchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedDuringPeriodValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Value of shares repurchased</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedDuringPeriodValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Stock Repurchased During Period, Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_StockRepurchasedDuringPeriodValue_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Stock repurchase</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentLiabilitiesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other Current Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentLiabilitiesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Current Liabilities Text Block</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_OtherCurrentLiabilitiesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other current liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PercentageOfAggregateAmountOfAllCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Percentage of aggregate amount of all commitments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PercentageOfAggregateAmountOfAllCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Percentage of Aggregate Amount of all Commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PercentageOfAggregateAmountOfAllCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Percentage of aggregate amount of all commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share Based Compensation Arrangement By Share Based Payment Award [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCommonStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Entity Common Stock, Shares Outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCommonStockSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Common Stock, Shares Outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentConvertibleTermsOfConversionFeature_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument conversion terms</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentConvertibleTermsOfConversionFeature_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Convertible, Terms of Conversion Feature</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestExpenseDebtAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Expense, Debt [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentGrossProfitPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segment gross profit percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentGrossProfitPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment gross profit percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SegmentGrossProfitPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Segment gross profit percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Accumulated Other Comprehensive Income (Loss), Net of Tax, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated Other Comprehensive Income (Loss), Net of Tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Accumulated other comprehensive loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accumulated other comprehensive loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ConsolidationItemsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Consolidation Items</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_ConsolidationItemsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Consolidation Items [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Payments to Acquire Property, Plant, and Equipment, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Purchases of property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Capital expenditures</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Payments to Acquire Property, Plant, and Equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Assets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Assets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Consolidated total assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_Assets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeStatementAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income Statement [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RatioOfIndebtednessToNetCapital1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Leverage ratio</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RatioOfIndebtednessToNetCapital1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Ratio of Indebtedness to Net Capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Restructuring Cost [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestRateCapMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Rate Cap [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestRateCapMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest Rate Caps [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestRateCapMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Interest Rate Cap [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Redemption, Period One [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2029 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentRedemptionPeriodOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Any Time and From Time to Time Prior to February 15, 2029 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DavidPHenryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">David P. Henry [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DavidPHenryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">David P. Henry.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DavidPHenryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">David P. Henry</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredIncomeTaxExpenseBenefit_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Deferred Income Tax Expense (Benefit), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredIncomeTaxExpenseBenefit_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred income taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredIncomeTaxExpenseBenefit_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred Income Tax Expense (Benefit)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SellingGeneralAndAdministrativeExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Selling, General and Administrative Expenses [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SellingGeneralAndAdministrativeExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Selling, General and Administrative Expense [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ChangeInContractWithCustomerLiabilityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Change in Contract with Customer, Liability [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareDilutedAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share, Diluted [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareDilutedAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Net income per share:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareDiluted_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Earnings Per Share, Diluted, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareDiluted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Diluted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EarningsPerShareDiluted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share, Diluted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Segment Reporting Information, by Segment [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segment Assets by Reportable Segment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingSegmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Operating Segments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingSegmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Operating Segments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Asset, Expected Amortization, Year Five</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">2031</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayableTrade_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accounts payable</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncreaseDecreaseInAccountsPayableTrade_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Accounts Payable, Trade</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_CityAreaCode_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">City Area Code</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_CityAreaCode_lbl" xlink:role="http://www.xbrl.org/2003/role/label">City Area Code</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LongTermDebtAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-Term Debt, Unclassified [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentIssuedPrincipal_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Aggregate principal amount notes sold</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentIssuedPrincipal_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Issued, Principal</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionsProFormaRevenue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Pro Forma Information, Pro Forma Revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionsProFormaRevenue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total net revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentFaceAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt Carrying Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentFaceAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Aggregate principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentFaceAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument, Face Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DebtInstrumentFaceAmount_lbl" xlink:role="http://www.xbrl.org/2009/role/netLabel">Outstanding principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Borrowing capacity in the form of letters of credit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Line of Credit Facility, Maximum Borrowing Capacity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Borrowing capacity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Business Acquisition [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheAMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">USD tranche A member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UsdTrancheAMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">USD Tranche A [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestRateFloorMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Floor Rate [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_InterestRateFloorMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest Rate Floor [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleDebtNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Convertible Notes, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ConvertibleDebtNoncurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Debt, Noncurrent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyLiabilityTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Product Warranty Liability [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyLiabilityTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Product Warranty Liability [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EarningsPerShareLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Earnings Per Share [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EarningsPerShareLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_EarningsPerShareLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Earnings Per Share [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentReportingInformationLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segment Reporting Information [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_SegmentReportingInformationLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segment Reporting Information [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Acquiree's Revenue since Acquisition Date, Actual</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total net revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JohnTCLeeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">John T C Lee [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JohnTCLeeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">John T C Lee.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_JohnTCLeeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">John T.C. Lee</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GuaranteesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Guarantees [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CostToPurchaseCappedCallTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cost to purchase capped call transactions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CostToPurchaseCappedCallTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cost To Purchase Capped Call Transactions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_CostToPurchaseCappedCallTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cost to purchase capped call transactions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Property, Plant and Equipment, Net, Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Property, Plant and Equipment, Net, Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Property, Plant and Equipment, Net, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Property, plant and equipment, net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PropertyPlantAndEquipmentNet_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Property, Plant and Equipment, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Right-of-Use Asset Obtained in Exchange for Finance Lease Liability</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Right-of-use assets obtained in exchange for finance lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoansUnderTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Term loans under term loan facility.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_TermLoansUnderTermLoanFacilityMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Term Loans Under Term Loan Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProceedsFromBankDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Proceeds from borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProceedsFromBankDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds from Bank Debt</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProceedsFromBankDebt_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Payments of deferred financing fees</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Cash and cash equivalents at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Cash and cash equivalents at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AociIncludingPortionAttributableToNoncontrollingInterestPeriodIncreaseDecrease_lbl" xlink:role="http://www.xbrl.org/2003/role/label">AOCI Including Portion Attributable to Noncontrolling Interest, Period Increase (Decrease)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AociIncludingPortionAttributableToNoncontrollingInterestPeriodIncreaseDecrease_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">AOCI Including Portion Attributable to Noncontrolling Interest, Period Increase (Decrease), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AociIncludingPortionAttributableToNoncontrollingInterestPeriodIncreaseDecrease_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Changes in accumulated other comprehensive (loss) Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingIncomeLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Operating Income (Loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OperatingIncomeLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Income from operations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillForeignCurrencyTranslationGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill, Foreign Currency Translation, Gain (Loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillForeignCurrencyTranslationGainLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Foreign currency translation, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillForeignCurrencyTranslationGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Foreign currency translation and measurement period adjustments, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillForeignCurrencyTranslationGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Foreign currency translation adjustments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SemiconductorMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Semiconductor.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_SemiconductorMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Semiconductor [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsByGeographicalAreasTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Net Revenues and Long-Lived Assets by Geographic Regions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsByGeographicalAreasTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RetainedEarningsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retained Earnings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RetainedEarningsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Retained Earnings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationShareReceivedPerCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of shares received per common shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationShareReceivedPerCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination Share Received Per Common Stock</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationShareReceivedPerCommonStock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Business combination share received per common stock.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UnallocatedCorporateExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Unallocated corporate expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UnallocatedCorporateExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unallocated corporate expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_UnallocatedCorporateExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Unallocated corporate expenses.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GeraldGColellaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Gerald G Colella [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GeraldGColellaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Gerald G Colella [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_GeraldGColellaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Gerald G. Colella</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Share-based Payment Arrangement, Noncash Expense, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock-based compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShareBasedCompensation_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Noncash Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueInputsLevel1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FairValueInputsLevel1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value, Inputs, Level 1 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ClassOfStockLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Class of Stock [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Provided by (Used in) Financing Activity, Including Discontinued Operation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net cash used in financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermDebtLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Short Term Debt [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermDebtLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-Term Debt [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LeaseCostTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Elements of Lease Payments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_LeaseCostTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Lease, Cost [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdopted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Change in accounting principle, accounting standards update, adopted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ChangeInAccountingPrincipleAccountingStandardsUpdateAdopted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Change in Accounting Principle, Accounting Standards Update, Adopted [true false]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredIncomeTaxLiabilitiesNet_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Deferred Income Tax Liabilities, Net, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredIncomeTaxLiabilitiesNet_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current deferred taxes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DeferredIncomeTaxLiabilitiesNet_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred Income Tax Liabilities, Net</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_Years3And4Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Years 3 and 4 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_Years3And4Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Years 3 and 4 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_Years3And4Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Years 3 and 4 member.</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfGoodwillTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accounts receivable</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finite-Lived Intangible Assets, Foreign Currency Translation Gain (Loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Foreign Currency Translation and Measurement Period Adjustments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CorporateDebtSecuritiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Corporate Obligations [Member]</link:label>
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          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityInteractiveDataCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Interactive Data Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeStatementLocationDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income Statement Location</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IncomeStatementLocationDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of Income Location, Balance [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PercentageOfAggregatePrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Percentage of aggregate principal amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PercentageOfAggregatePrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Percentage Of Aggregate Principal Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PercentageOfAggregatePrincipalAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Percentage of aggregate principal amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash flows from operating activities:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accounting Standards Update and Change in Accounting Principle [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NewAccountingPronouncementsAndChangesInAccountingPrinciplesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Recent Accounting Pronouncements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination, Consideration Transferred, Equity Interest, Share Issued, Number of Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Aggregate number of common stock issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrualPeriodIncreaseDecrease_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Standard and Extended Product Warranty Accrual, Period Increase (Decrease), Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrualPeriodIncreaseDecrease_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Charges to warranty liability</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ProductWarrantyAccrualPeriodIncreaseDecrease_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Standard and Extended Product Warranty Accrual, Period Increase (Decrease)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerAssetNet_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Contract with Customer, Asset, after Allowance for Credit Loss, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerAssetNet_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contract with Customer, Asset, after Allowance for Credit Loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ContractWithCustomerAssetNet_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Contract assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockDividendsPerShareDeclared_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash dividend, per common share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CommonStockDividendsPerShareDeclared_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Common Stock, Dividends, Per Share, Declared</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BorrowingsUnderEuroTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Borrowings under Euro Tranche B member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BorrowingsUnderEuroTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Borrowings under Euro Tranche B [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BorrowingsUnderEuroTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Borrowings under Euro Tranche B [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityTaxIdentificationNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Tax Identification Number</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityTaxIdentificationNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Tax Identification Number</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenuesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net revenues:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenuesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenues [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AccumulatedAmortizationAndImpairmentCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accumulated Amortization and Impairment Charges</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AccumulatedAmortizationAndImpairmentCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated Amortization and Impairment Charges</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_AccumulatedAmortizationAndImpairmentCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Accumulated amortization and impairment charges.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ShortTermBorrowingsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-Term Debt [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentPremiumPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Debt instrument premium percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentPremiumPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt Instrument Premium Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_DebtInstrumentPremiumPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Debt instrument premium percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PaymentsForCostOfCappedCallTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Payments for cost of capped call transactions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PaymentsForCostOfCappedCallTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Payments for cost of capped call transactions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_PaymentsForCostOfCappedCallTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Payments for Cost Of Capped Call Transactions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Basis of Presentation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_WeightedAverageRevenueGrowthRateFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average revenue growth rate future undiscounted cash flows.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_WeightedAverageRevenueGrowthRateFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Revenue Growth Rate Future Undiscounted Cash Flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_WeightedAverageRevenueGrowthRateFutureUndiscountedCashFlows_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted-average revenue growth rate future undiscounted cash flows</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_LocalPhoneNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Local Phone Number</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_LocalPhoneNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Local Phone Number</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated Other Comprehensive Income (Loss) [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Liabilities, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_CN_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">China [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_CN_lbl" xlink:role="http://www.xbrl.org/2003/role/label">CHINA</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Denominator:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average common shares outstanding:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Number of Shares Outstanding, Diluted [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationPricePerShareOfCommonStockInCash_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Price per share of common stock in cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationPricePerShareOfCommonStockInCash_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Business Combination Price Per Share Of Common Stock In Cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="mksi_BusinessCombinationPricePerShareOfCommonStockInCash_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Business combination, price per share of common stock in cash.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsOfFinancingCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Payments of Financing Costs, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsOfFinancingCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Payments of Financing Costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsOfFinancingCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Payments of deferred financing fees</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_PaymentsOfFinancingCosts_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Payments of deferred financing fees</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashAcquiredFromAcquisition_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Less: Cash and cash equivalents acquired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_CashAcquiredFromAcquisition_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash Acquired from Acquisition</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherCurrentLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other Current Liabilities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherCurrentLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Current Liabilities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DisaggregationOfRevenueLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disaggregation of Revenue [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_DisaggregationOfRevenueLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disaggregation of Revenue [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherSundryLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_OtherSundryLiabilitiesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Sundry Liabilities, Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue from Contract with Customer, Excluding Assessed Tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Revenues by segment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total net revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetIncomeLossAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Numerator:</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_NetIncomeLossAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Net Income (Loss) Attributable to Parent [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Perfomance period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedPeriodStartLabel">Beginning balance, Accumulated Impairment Loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedPeriodEndLabel">Ending balance, Accumulated Impairment Loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Goodwill, Impaired, Accumulated Impairment Loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance, Accumulated Impairment Loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance, Accumulated Impairment Loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityEmergingGrowthCompany_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Emerging Growth Company</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityEmergingGrowthCompany_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Emerging Growth Company</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Indefinite-lived Intangible Assets</link:label>
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          <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_EquitySecuritiesFvNiCurrentAndNoncurrent" xlink:to="us-gaap_EquitySecuritiesFvNiCurrentAndNoncurrent_lbl"/>
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          <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" xlink:to="us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_lbl"/>
          <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityIncorporationStateCountryCode" xlink:to="dei_EntityIncorporationStateCountryCode_lbl"/>
          <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_PreferredStockSharesIssued" xlink:to="us-gaap_PreferredStockSharesIssued_lbl"/>
          <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_BalanceSheetLocationDomain" xlink:to="us-gaap_BalanceSheetLocationDomain_lbl"/>
          <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="mksi_BaseRateBorrowingsMember" xlink:to="mksi_BaseRateBorrowingsMember_lbl"/>
          <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:to="us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_lbl"/>
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  <xsd:element id="mksi_DebtInstrumentCurrentConvertibleConversionPrice" name="DebtInstrumentCurrentConvertibleConversionPrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="mksi_DebtInstrumentPrincipalAmountDenominationForConversionIntoCommonStock" name="DebtInstrumentPrincipalAmountDenominationForConversionIntoCommonStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_AnnualStepDownMember" name="AnnualStepDownMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_MichelleMMcCarthyMember" name="MichelleMMcCarthyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_OriginalIssueDiscountMember" name="OriginalIssueDiscountMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_TermLoansUnderTermLoanFacilityMember" name="TermLoansUnderTermLoanFacilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ScheduleOfAllocationOfPurchasePriceTableTextBlock" name="ScheduleOfAllocationOfPurchasePriceTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ReportingUnitGoodwill" name="ReportingUnitGoodwill" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_InitialCommitmentFeePercentage" name="InitialCommitmentFeePercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ConvertibleDebtCappedCallsPrice" name="ConvertibleDebtCappedCallsPrice" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_NonCurrentInterestRateFairValueHedgeLiabilitiesAtFairValue" name="NonCurrentInterestRateFairValueHedgeLiabilitiesAtFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_OriginalIssueDiscountPercentageOfPrincipalAmount" name="OriginalIssueDiscountPercentageOfPrincipalAmount" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ReductionInInterestExpense" name="ReductionInInterestExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_UsdTrancheBMember" name="UsdTrancheBMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DebtInstrumentRedemptionPricePercentageOfPrincipalAmountMayRedeem" name="DebtInstrumentRedemptionPricePercentageOfPrincipalAmountMayRedeem" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ScheduleOfCapitalExpenditureDepreciationAndAmortizationAndAssetsReportableSegmentsTableTextBlock" name="ScheduleOfCapitalExpenditureDepreciationAndAmortizationAndAssetsReportableSegmentsTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNonCurrentAccruedCompensation" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNonCurrentAccruedCompensation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_WeightedAverageRevenueGrowthRateFutureUndiscountedCashFlows" name="WeightedAverageRevenueGrowthRateFutureUndiscountedCashFlows" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_JacquelineFMoloneyMember" name="JacquelineFMoloneyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DebtInstrumentIssuedPrincipalOptionToPurchase" name="DebtInstrumentIssuedPrincipalOptionToPurchase" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_RestructuringExpense" name="RestructuringExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_BorrowingsUnderEuroTrancheBMember" name="BorrowingsUnderEuroTrancheBMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_EuriborRateFloorMember" name="EuriborRateFloorMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_FeesAndExpensesRelatedToDebtActivities" name="FeesAndExpensesRelatedToDebtActivities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_FederalFundsRateMember" name="FederalFundsRateMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_CurrentInterestRateFairValueHedgeAssetAtFairValue" name="CurrentInterestRateFairValueHedgeAssetAtFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_AtotechLimitedMember" name="AtotechLimitedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateralCurrent" name="DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateralCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_DeferredRevenueMember" name="DeferredRevenueMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_PercentageOfAggregatePrincipalAmount" name="PercentageOfAggregatePrincipalAmount" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_O2025Q3DividendsMember" name="O2025Q3DividendsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_CashEquivalentsFairValueDisclosure" name="CashEquivalentsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_SegmentAssets" name="SegmentAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_SixthAmendmentMember" name="SixthAmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ElectronicsMember" name="ElectronicsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_AccumulatedAmortizationAndImpairmentCharges" name="AccumulatedAmortizationAndImpairmentCharges" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_NewRevolvingFacilityMember" name="NewRevolvingFacilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_OccurrenceOfAChangeOfControlTriggeringEventMember" name="OccurrenceOfAChangeOfControlTriggeringEventMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_BusinessCombinationShareReceivedPerCommonStock" name="BusinessCombinationShareReceivedPerCommonStock" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="mksi_TermLoansUnderNewTermLoanFacilityMember" name="TermLoansUnderNewTermLoanFacilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_BaseRateBorrowingsMember" name="BaseRateBorrowingsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_Year5Member" name="Year5Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_UsdTrancheBSecondAmmendmentMember" name="UsdTrancheBSecondAmmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoInterestExpense" name="DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoInterestExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_UnallocatedCorporateExpenses" name="UnallocatedCorporateExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_EquipmentSolutionsMember" name="EquipmentSolutionsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DerivativeInstrumentsGainLossNotDesignatedAsHedgingInstrumentsLineItems" name="DerivativeInstrumentsGainLossNotDesignatedAsHedgingInstrumentsLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_TermLoanFacilityMember" name="TermLoanFacilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ScheduleOfEarningsPerShareTable" name="ScheduleOfEarningsPerShareTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ChangeInContractWithCustomerLiabilityTable" name="ChangeInContractWithCustomerLiabilityTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_RepurchaseOfDebtPercentage" name="RepurchaseOfDebtPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_FirstLienNetLeverageRatioMember" name="FirstLienNetLeverageRatioMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_UsdTrancheAMember" name="UsdTrancheAMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_CustomerAdvancesMember" name="CustomerAdvancesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DebtIssuanceCostsAmortizationPeriod" name="DebtIssuanceCostsAmortizationPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ScheduleOfBusinessCombinationAcquireeRevenueAndIncomeBeforeIncomeTaxesTableTextBlock" name="ScheduleOfBusinessCombinationAcquireeRevenueAndIncomeBeforeIncomeTaxesTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_DebtInstrumentConvertibleApplicableConversionPrice" name="DebtInstrumentConvertibleApplicableConversionPrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="mksi_OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossNetOfTax" name="OtherComprehensiveIncomeLossNetInvestmentHedgeGainLossNetOfTax" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_MinimumPercentageOfEarningsBeforeInterestTaxesDepreciationAndAmortization" name="MinimumPercentageOfEarningsBeforeInterestTaxesDepreciationAndAmortization" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_NonCurrentLeaseLiability" name="NonCurrentLeaseLiability" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_PercentageOfAggregateAmountOfAllCommitments" name="PercentageOfAggregateAmountOfAllCommitments" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_CompletedTechnologyRightsMember" name="CompletedTechnologyRightsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_O2026Q3DividendsMember" name="O2026Q3DividendsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_UsdTrancheBFirstAmmendmentMember" name="UsdTrancheBFirstAmmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_SegmentGrossProfitLoss" name="SegmentGrossProfitLoss" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_EquipmentSolutionsBusinessMember" name="EquipmentSolutionsBusinessMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_NewTermLoanFacilityMember" name="NewTermLoanFacilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_EstimatedAggregatePrincipalAmountPercentage" name="EstimatedAggregatePrincipalAmountPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_IncrementalTrancheBLoansFourthAmendmentMember" name="IncrementalTrancheBLoansFourthAmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFour" name="LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_ExpenseOfRestructuringActivitiesAndOtherTextBlock" name="ExpenseOfRestructuringActivitiesAndOtherTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ConvertibleDebtCappedCallsInitialPrice" name="ConvertibleDebtCappedCallsInitialPrice" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_IncrementalUsdTrancheBMember" name="IncrementalUsdTrancheBMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_StepUpMember" name="StepUpMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ProceedsFromPaymentsForEmployeeStockAwards" name="ProceedsFromPaymentsForEmployeeStockAwards" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeited" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeited" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_EuroTrancheBMember" name="EuroTrancheBMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DeferredFinancingCostsInLongTermDebt" name="DeferredFinancingCostsInLongTermDebt" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_OtherCurrentAssetsFairValueDisclosure" name="OtherCurrentAssetsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_BusinessCombinationIntegrationReversalOfAcquisitionAndIntegrationCosts" name="BusinessCombinationIntegrationReversalOfAcquisitionAndIntegrationCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_SeniorNotesDue2034Member" name="SeniorNotesDue2034Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_LoansIssuanceDiscountRate" name="LoansIssuanceDiscountRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_PrepaymentPremiumPercentageOfAggregatePrincipalAmount" name="PrepaymentPremiumPercentageOfAggregatePrincipalAmount" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_InterestRateHedgeMember" name="InterestRateHedgeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_EventOfCertainDevelopmentsAffectingTaxationMember" name="EventOfCertainDevelopmentsAffectingTaxationMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_IncrementalBorrowings" name="IncrementalBorrowings" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_ExpenseChargesRelatedToIndefiniteReinvestmentAssertion" name="ExpenseChargesRelatedToIndefiniteReinvestmentAssertion" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_IntangibleAssetsFairValue" name="IntangibleAssetsFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_DavidPHenryMember" name="DavidPHenryMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_GeraldGColellaMember" name="GeraldGColellaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_TermSofrRatePlusApplicableCreditSpreadAdjustmentMember" name="TermSofrRatePlusApplicableCreditSpreadAdjustmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_EquipmentSolutionsDivisionMember" name="EquipmentSolutionsDivisionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_NumberOfTradingDays" name="NumberOfTradingDays" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_BacklogMember" name="BacklogMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_SegmentGrossProfitPercentage" name="SegmentGrossProfitPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_QuantitativeAssessmentTableTextBlock" name="QuantitativeAssessmentTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ElizabethAMember" name="ElizabethAMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_RamakumarMayampurathMember" name="RamakumarMayampurathMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ExpenseOfRestructuringActivitiesAndOtherAbstract" name="ExpenseOfRestructuringActivitiesAndOtherAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_VacuumSolutionsDivisionMember" name="VacuumSolutionsDivisionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_CappedCallTransactionReductionOrOffsetPerShare" name="CappedCallTransactionReductionOrOffsetPerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_CompletedTechnologyMember" name="CompletedTechnologyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_LoanVoluntaryPrepaymentAmount" name="LoanVoluntaryPrepaymentAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_BusinessCombinationPricePerShareOfCommonStockInCash" name="BusinessCombinationPricePerShareOfCommonStockInCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_GoodwillAndIntangibleAssetsTable" name="GoodwillAndIntangibleAssetsTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ConvertibleDebtCappedCallsInitialPricePerShare" name="ConvertibleDebtCappedCallsInitialPricePerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="mksi_MutualFundsAndExchangeTradedFundsMember" name="MutualFundsAndExchangeTradedFundsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_CurrentInterestRateFairValueHedgeLiabilitiesAtFairValue" name="CurrentInterestRateFairValueHedgeLiabilitiesAtFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_InterestRateHegesMember" name="InterestRateHegesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ScheduleOfRestructuringAndOtherCostTable" name="ScheduleOfRestructuringAndOtherCostTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_LineOfCreditFacilityMinimumAdditionalBorrowingCapacity" name="LineOfCreditFacilityMinimumAdditionalBorrowingCapacity" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_TermSofrBorrowingsMember" name="TermSofrBorrowingsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DebtInstrumentPremiumPercentage" name="DebtInstrumentPremiumPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_NatureOfTradingArrangement" name="NatureOfTradingArrangement" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_IntangibleAssetsUsefulLifeFutureUndiscountedCashFlows" name="IntangibleAssetsUsefulLifeFutureUndiscountedCashFlows" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_PhotonicsSolutionsDivisionMember" name="PhotonicsSolutionsDivisionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ContractWithCustomerAmountOfDeferredRevenueAndCustomerAdvancesRecognized" name="ContractWithCustomerAmountOfDeferredRevenueAndCustomerAdvancesRecognized" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_PensionAndDeferredCompensationPlanAssets" name="PensionAndDeferredCompensationPlanAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_GoodwillAndIntangibleAssetsLineItems" name="GoodwillAndIntangibleAssetsLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_PaymentsAndAdjustmentForRestructuring" name="PaymentsAndAdjustmentForRestructuring" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_ChangeInContractWithCustomerLiabilityLineItems" name="ChangeInContractWithCustomerLiabilityLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_AcquisitionDateLineItems" name="AcquisitionDateLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_JohnTCLeeMember" name="JohnTCLeeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_CurrentAssetsFairValueDisclosure" name="CurrentAssetsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_DebtInstrumentConversionRateShares" name="DebtInstrumentConversionRateShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_LineOfCreditFacilityRenewalPeriod" name="LineOfCreditFacilityRenewalPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_NonCurrentAssetsFairValueDisclosure" name="NonCurrentAssetsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_EuroTrancheMember" name="EuroTrancheMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_OtherCurrentLiabilitiesFairValueDisclosure" name="OtherCurrentLiabilitiesFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_OtherNonCurrentLiabilitiesFairValueDisclosure" name="OtherNonCurrentLiabilitiesFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_NotesMember" name="NotesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_SemiconductorMember" name="SemiconductorMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_InProcessResearchAndDevelopmentReclassifiedIntoCompletedTechnology" name="InProcessResearchAndDevelopmentReclassifiedIntoCompletedTechnology" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_ScheduledQuarterlyPaymentsPercentageOfOriginalPrincipalAmount" name="ScheduledQuarterlyPaymentsPercentageOfOriginalPrincipalAmount" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ConvertibleSeniorNotesDue2030Member" name="ConvertibleSeniorNotesDue2030Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_FacilityInSouthKoreaMember" name="FacilityInSouthKoreaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_NonCurrentInterestRateFairValueHedgeAssetAtFairValue" name="NonCurrentInterestRateFairValueHedgeAssetAtFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_DurationOfTradingArrangement" name="DurationOfTradingArrangement" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_AccumulatedOtherComprehensiveIncomeLossChangeInNetInvestmentHedgeMember" name="AccumulatedOtherComprehensiveIncomeLossChangeInNetInvestmentHedgeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_IncreaseDecreaseCurrentAndNonCurrentAccruedCompensation" name="IncreaseDecreaseCurrentAndNonCurrentAccruedCompensation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_EarningsPerShareLineItems" name="EarningsPerShareLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_AnyTimePriorToFebruary152029Member" name="AnyTimePriorToFebruary152029Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_BorrowingsUnderNewRevolvingFacilityMember" name="BorrowingsUnderNewRevolvingFacilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DebtInstrumentConvertibleConversionPricePercentage" name="DebtInstrumentConvertibleConversionPricePercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeitedWeightedAverageGrantDateFairValue" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndForfeitedWeightedAverageGrantDateFairValue" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_OtherCountriesMember" name="OtherCountriesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_TimeDepositsAndCertificatesOfDepositMember" name="TimeDepositsAndCertificatesOfDepositMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DerivativeAndHedgingTable" name="DerivativeAndHedgingTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_RestructuringCostAndOtherCostLineItems" name="RestructuringCostAndOtherCostLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoCostOfRevenues" name="DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOciIntoCostOfRevenues" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_GeneralMetalFinishingMember" name="GeneralMetalFinishingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_OtherInterestIncomeExpenseNet" name="OtherInterestIncomeExpenseNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_ChangesInValueOfFinancialInstrumentsDesignatedAsCashFlowHedgesMember" name="ChangesInValueOfFinancialInstrumentsDesignatedAsCashFlowHedgesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_OtherCurrentLiabilitiesTextBlock" name="OtherCurrentLiabilitiesTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ContractWithCustomerLiabilityAdditions" name="ContractWithCustomerLiabilityAdditions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_MaterialsSolutionsDivisionMember" name="MaterialsSolutionsDivisionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_DiscountRateFutureUndiscountedCashFlows" name="DiscountRateFutureUndiscountedCashFlows" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_AtotechMember" name="AtotechMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_IncrementalTrancheBLoansMember" name="IncrementalTrancheBLoansMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_AnyTimeAndFromTimeToTimePriorToFebruary152029Member" name="AnyTimeAndFromTimeToTimePriorToFebruary152029Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_IsraeliPensionAssetsMember" name="IsraeliPensionAssetsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_GroupInsuranceContractsMember" name="GroupInsuranceContractsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_MeasurementPeriodMember" name="MeasurementPeriodMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_JamesASchreinerMember" name="JamesASchreinerMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_ReductionToInterestExpense" name="ReductionToInterestExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_Years3And4Member" name="Years3And4Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_NumberOfCustomersAccountedForTenOrMorePercentOfRevenue" name="NumberOfCustomersAccountedForTenOrMorePercentOfRevenue" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_ScheduleOfGoodwillAssociatedWithReportableSegmentsTableTextBlock" name="ScheduleOfGoodwillAssociatedWithReportableSegmentsTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_MinimumPercentageOfIncomeTaxPaymentNetOfRefundsReceived" name="MinimumPercentageOfIncomeTaxPaymentNetOfRefundsReceived" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_WeightedAverageNumberOfDilutedShares" name="WeightedAverageNumberOfDilutedShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_CappedCallTransactionsMember" name="CappedCallTransactionsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_IncrementalTrancheBLoansSecondAmendmentMember" name="IncrementalTrancheBLoansSecondAmendmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_PaymentsForCostOfCappedCallTransactions" name="PaymentsForCostOfCappedCallTransactions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_BorrowingsUnderRevolvingFacilityMember" name="BorrowingsUnderRevolvingFacilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_OutstandingDebtUnderInvestmentHedges" name="OutstandingDebtUnderInvestmentHedges" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="mksi_ElectronicsAndPackagingMember" name="ElectronicsAndPackagingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_SpecialtyIndustrialMember" name="SpecialtyIndustrialMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="mksi_NumberOfConsecutiveTradingDays" name="NumberOfConsecutiveTradingDays" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="mksi_CostToPurchaseCappedCallTransactions" name="CostToPurchaseCappedCallTransactions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_DeferredCompensationPlanAssetsFairValueDisclosure" name="DeferredCompensationPlanAssetsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="mksi_PatentsTrademarksTradeNamesAndOtherMember" name="PatentsTrademarksTradeNamesAndOtherMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
</xsd:schema>
