Segment Reporting - Summary of Operating Segment Expenses (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
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| Segment Reporting | ||||||||||
| External R&D expense | $ 58,234 | $ 62,401 | $ 110,048 | $ 111,079 | ||||||
| Equity-based compensation expense | 37,907 | 37,846 | ||||||||
| Depreciation and amortization expense | 632 | 810 | ||||||||
| Loss on disposal of property and equipment | 3 | 0 | ||||||||
| Other non-operating expense/(income), net | (570) | (127) | (1,360) | (171) | ||||||
| Net loss | 109,896 | $ 105,510 | 110,031 | $ 74,723 | 215,406 | 184,754 | ||||
| Operating segment | ||||||||||
| Segment Reporting | ||||||||||
| Employee related expense | [1] | 37,445 | 32,484 | 74,971 | 55,422 | |||||
| External expense - G&A | 16,597 | 14,952 | 32,729 | 23,895 | ||||||
| Other segment items | [2] | 6,573 | 6,273 | 13,082 | 11,531 | |||||
| Equity-based compensation expense | 19,662 | 24,433 | 37,907 | 37,846 | ||||||
| Depreciation and amortization expense | 297 | 417 | 632 | 810 | ||||||
| Loss on disposal of property and equipment | 3 | |||||||||
| Other non-operating expense/(income), net | 995 | (2,078) | 4,489 | (4,445) | ||||||
| Net loss | 109,896 | 110,031 | $ 215,406 | 184,754 | ||||||
| Description-Other segment related expense | Consists of other segment expenses related to supplies, corporate and facilities expenses. | |||||||||
| Operating segment | Apitegromab | ||||||||||
| Segment Reporting | ||||||||||
| External R&D expense | 22,948 | 27,956 | $ 43,209 | 47,257 | ||||||
| Operating segment | SRK-181 | ||||||||||
| Segment Reporting | ||||||||||
| External R&D expense | 9 | 792 | 45 | 1,902 | ||||||
| Operating segment | SRK-439 | ||||||||||
| Segment Reporting | ||||||||||
| External R&D expense | 3,760 | 2,575 | 5,519 | 6,854 | ||||||
| Operating segment | Early research and other | ||||||||||
| Segment Reporting | ||||||||||
| External R&D expense | $ 1,610 | $ 2,227 | $ 2,820 | $ 3,682 | ||||||
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- Definition The current period expense charged against earnings on long-lived, physical assets not used in production, and which are not intended for resale, to allocate or recognize the cost of such assets over their useful lives; or to record the reduction in book value of an intangible asset over the benefit period of such asset; or to reflect consumption during the period of an asset that is not used in production. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of gain (loss) on sale or disposal of property, plant and equipment assets, excluding oil and gas property and timber property. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of expense for salary, wage, profit sharing; incentive and equity-based compensation; and other employee benefit. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of general and administrative expense classified as other. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of income (expense) related to nonoperating activities, classified as other. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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- Definition Amount of other expense (income) and loss (gain) calculated as difference between segment revenue and separately disclosed expense category to arrive at segment profit (loss). Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Description of composition of other segment item not separately disclosed. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of noncash expense for share-based payment arrangement. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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