| Schedule of Revenue |
Disaggregation of total revenues by nature is as follows: | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | (in thousands) | 2026 | | 2025 | | 2026 | | 2025 | | Product sales, net | $ | 118,129 | | | $ | 90,077 | | | $ | 211,502 | | | $ | 157,891 | | | Product supply revenue | 1,976 | | | 6,185 | | | 2,330 | | | 6,439 | | | Licensing revenue | 96 | | | 20 | | | 147 | | | 5,040 | | | Non-cash royalty revenue related to the sale of future royalties | 676 | | | 1,380 | | | 1,371 | | | 2,406 | | | Total revenues | $ | 120,877 | | | $ | 97,662 | | | $ | 215,350 | | | $ | 171,776 | |
Total product sales, net was as follows: | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | (in thousands) | 2026 | | 2025 | | 2026 | | 2025 | | Product sales, net | | | | | | | | | IBSRELA | $ | 86,243 | | | $ | 65,045 | | | $ | 156,317 | | | $ | 109,448 | | | XPHOZAH | 31,886 | | | 25,032 | | | 55,185 | | | 48,443 | | | Total product sales, net | $ | 118,129 | | | $ | 90,077 | | | $ | 211,502 | | | $ | 157,891 | | Product sales, net as a percentage of total revenues | 97.7 | % | | 92.2 | % | | 98.2 | % | | 91.9 | % |
The following table summarizes total revenues by collaboration partner: | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | (in thousands) | 2026 | | 2025 | | 2026 | | 2025 | | Licensing revenue | | | | | | | | | | | | | | | | Fosun Pharma | $ | 95 | | | $ | — | | | $ | 115 | | | $ | 5,000 | | Knight | 1 | | | 20 | | | 32 | | | 40 | | | | | | | | | | Total licensing revenue | $ | 96 | | | $ | 20 | | | $ | 147 | | | $ | 5,040 | | | Product supply revenue | | | | | | | | Fosun Pharma | $ | 1,976 | | | $ | — | | | $ | 2,328 | | | $ | — | | Kyowa Kirin | — | | | 6,185 | | | 2 | | | 6,185 | | Knight | — | | | — | | | — | | | 254 | | Total supply revenue | $ | 1,976 | | | $ | 6,185 | | | $ | 2,330 | | | $ | 6,439 | | | Non-cash royalty revenue related to the sale of future royalties | | | | | | | | Kyowa Kirin | $ | 676 | | | $ | 1,380 | | | $ | 1,371 | | | $ | 2,406 | |
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| Schedule of Revenue from Customers as a Percentage of Total Product Revenue, Net |
Gross product sales from Customers accounting for more than 10% of total revenues were as follows: | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | 2026 | | 2025 | | 2026 | | 2025 | Customers(1) | | | | | | | | | BioRidge Pharma, LLC | 76.3 | % | | 61.1 | % | | 80.3 | % | | 62.2 | % | | Cencora, Inc. | 16.0 | % | | 20.5 | % | | 16.5 | % | | 19.5 | % | | McKesson Corporation | 14.4 | % | | 20.7 | % | | 15.0 | % | | 19.1 | % | | Cardinal Health, Inc. | 14.4 | % | | 23.4 | % | | 13.7 | % | | 22.8 | % | | Caremark, LLC | 13.4 | % | | — | % | | 12.8 | % | | — | % | | | | | | | | | | | | | | | | |
(1)The total of the above percentages exceeds 100% as the numerators used in the calculations represent gross product sales for each Customer, as opposed to product sales, net as presented in our condensed statements of operations and comprehensive loss.
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| Schedule of Gross To Net Adjustments of Revenue |
The activities and ending reserve balances for each significant category of GTN adjustments on product sales, net, which constitute variable consideration, were as follows: | | | | | | | | | | | | | | | | | | | | | | | | (in thousands) | Discounts and Chargebacks | | Rebates, Wholesaler and GPO Fees | | Copay Assistance and Returns | | Total | | Balance as of December 31, 2025 | $ | 1,693 | | | $ | 34,456 | | | $ | 9,274 | | | $ | 45,423 | | Provisions(1) | 17,983 | | | 70,766 | | | 25,383 | | | 114,132 | | | Credits/payments | (16,957) | | | (58,732) | | | (24,495) | | | (100,184) | | | Balance as of June 30, 2026 | $ | 2,719 | | | $ | 46,490 | | | $ | 10,162 | | | $ | 59,371 | |
(1)Adjustments to prior period provisions recorded in the current period were not material.
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