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License, collaboration and commercial agreements - Pfizer, Inc. (Details) - USD ($) $ in Thousands		1 Months Ended	3 Months Ended		6 Months Ended
	Jul. 11, 2012	Apr. 30, 2025	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
License, collaboration and commercial agreements
Intangible asset			$ 17,123		$ 17,123
Interest expense			$ 360	$ 212	$ 743	$ 404
Pfizer
License, collaboration and commercial agreements
One-time cash payment	$ 1,500
Shares issued	16,001
Intangible asset		$ 15,000
Interest expense		$ 500
Royalty obligations term		10 years
Pfizer \| Achievement of FDA approval
License, collaboration and commercial agreements
Potential milestone payments		$ 7,500
Pfizer \| Achievement of FDA approval anniversary
License, collaboration and commercial agreements
Potential milestone payments		8,000
Pfizer \| Achievement of certain development and commercialization milestones
License, collaboration and commercial agreements
Potential milestone payments		2,000
Pfizer \| Achievement of certain sales milestones
License, collaboration and commercial agreements
Potential milestone payments		$ 110,000