| Summary of Breakdown of Net Loss by Category |
The following is a breakdown of net loss by category for the three and six months ended June 30, 2026 and 2025 as managed by the chief operating decision maker (in thousands).
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Three Months Ended |
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Six Months Ended |
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June 30, |
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June 30, |
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June 30, |
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June 30, |
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2026 |
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2025 |
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2026 |
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2025 |
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License revenue |
$ |
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— |
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$ |
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— |
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$ |
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— |
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$ |
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3,000 |
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Operating expenses: |
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EVO756 |
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13,036 |
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10,189 |
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19,902 |
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14,859 |
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EVO301 |
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870 |
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1,375 |
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1,495 |
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4,402 |
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Other research and development |
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9,021 |
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5,455 |
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15,691 |
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9,512 |
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Total external research and development |
$ |
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22,927 |
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$ |
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17,019 |
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$ |
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37,088 |
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$ |
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28,773 |
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Research and development personnel costs |
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3,485 |
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2,619 |
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6,643 |
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5,227 |
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Total research and development operating expenses |
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26,412 |
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19,638 |
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43,731 |
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34,000 |
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General and administrative operating expenses |
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6,232 |
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1,736 |
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10,826 |
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3,660 |
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General and administrative personnel costs |
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2,251 |
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1,620 |
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4,292 |
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3,366 |
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Total general and administrative operating expenses |
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8,483 |
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3,356 |
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15,118 |
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7,026 |
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Total operating expenses |
$ |
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34,895 |
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$ |
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22,994 |
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$ |
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58,849 |
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$ |
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41,026 |
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Other income, net |
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2,649 |
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9,429 |
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4,929 |
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9,904 |
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Net loss |
$ |
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(32,246 |
) |
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$ |
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(13,565 |
) |
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$ |
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(53,920 |
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$ |
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(28,122 |
) |
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