| Schedule of Reconciliation of Segment Loss Before Income Taxes and Total Consolidated Loss Before Income Taxes |
The following table presents selected financial information with respect to the Company’s single operating segment for the three and six months ended June 30, 2026 and 2025 (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | Therapeutics Segment | | Three Months Ended June 30, | | Six Months Ended June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | | | | | | | | | | | Product revenue, net | $ | 3,604 | | | $ | — | | | $ | 3,604 | | | $ | — | | | | Less: | | | | | | | | | | Cost of goods sold | 93 | | | — | | | 93 | | | — | | | | External research and development expenses - TV programs, including cost sharing | 40,419 | | | 37,594 | | | 78,883 | | | 84,052 | | | Other research and development expenses, including small molecule programs | 16,494 | | | 24,847 | | | 40,048 | | | 54,347 | | | Personnel related research and development expenses | 40,106 | | | 40,255 | | | 81,934 | | | 80,524 | | | | Total research and development expenses | 97,019 | | | 102,696 | | | 200,865 | | | 218,923 | | | Personnel related selling, general and administrative expenses | 22,921 | | | 20,115 | | | 45,485 | | | 38,853 | | | Other selling, general and administrative expenses | 13,362 | | | 12,152 | | | 24,309 | | | 22,767 | | | | Total selling, general and administrative expenses | 36,283 | | | 32,267 | | | 69,794 | | | 61,620 | | | | Intangible asset amortization | $ | 750 | | | $ | — | | | $ | 750 | | | $ | — | | | | Segment operating expenses | 134,145 | | | 134,963 | | | 271,502 | | | 280,543 | | | | | | | | | | | | | Segment loss from operations | (130,541) | | | (134,963) | | | (267,898) | | | (280,543) | | | | Segment interest and other income, net | 2,988 | | | 10,844 | | | 11,898 | | | 23,454 | | | Segment net loss | $ | (127,553) | | | $ | (124,119) | | | $ | (256,000) | | | $ | (257,089) | | |
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