Organization and basis of presentation - Additional Information (Detail) - USD ($) $ in Thousands |
1 Months Ended | 3 Months Ended | 6 Months Ended | |||||
|---|---|---|---|---|---|---|---|---|
Jul. 31, 2026 |
May 31, 2026 |
May 31, 2025 |
May 31, 2024 |
May 31, 2023 |
Jun. 30, 2026 |
Jun. 30, 2026 |
Dec. 31, 2025 |
|
| Organization, Consolidation and Presentation of Financial Statements [Line Items] | ||||||||
| Cash and cash equivalents | $ 30,381 | $ 30,381 | $ 18,303 | |||||
| Accumulated deficit | 666,745 | 666,745 | $ 642,201 | |||||
| Amoytop | Amoytop License and Research Collaboration | ||||||||
| Organization, Consolidation and Presentation of Financial Statements [Line Items] | ||||||||
| Upfront payment received | $ 25,000 | $ 25,000 | $ 1,000 | $ 1,500 | $ 7,000 | $ 27,800 | $ 27,800 | |