0001517022 2026-08-03 2026-08-03 0001517022 1 2026-08-03 2026-08-03 0001517022 2 2026-08-03 2026-08-03 0001517022 3 2026-08-03 2026-08-03 0001517022 4 2026-08-03 2026-08-03 0001517022 5 2026-08-03 2026-08-03 0001517022 6 2026-08-03 2026-08-03 0001517022 7 2026-08-03 2026-08-03 0001517022 8 2026-08-03 2026-08-03 0001517022 9 2026-08-03 2026-08-03 0001517022 10 2026-08-03 2026-08-03 0001517022 11 2026-08-03 2026-08-03 0001517022 12 2026-08-03 2026-08-03 iso4217:USD pure shares S-8 S-8 EX-FILING FEES 0001517022 Akebia Therapeutics, Inc. N/A false false false false false false false false false false false false S-8 Akebia Therapeutics, Inc. Equity Common Stock, $0.00001 par value per share true 90600 3.14 284484.00 0.0001381 39.29 Equity Common Stock, $0.00001 par value per share true 190063 2.73 518871.99 0.0001381 71.66 Equity Common Stock, $0.00001 par value per share true 51825 2.21 114533.25 0.0001381 15.82 Equity Common Stock, $0.00001 par value per share true 22576 1.58 35670.08 0.0001381 4.93 Equity Common Stock, $0.00001 par value per share true 61843 1.61 99567.23 0.0001381 13.76 Equity Common Stock, $0.00001 par value per share true 32675 1.41 46071.75 0.0001381 6.37 Equity Common Stock, $0.00001 par value per share true 46200 1.31 60522.00 0.0001381 8.36 Equity Common Stock, $0.00001 par value per share true 631600 1.39 877924.00 0.0001381 121.25 Equity Common Stock, $0.00001 par value per share true 200400 1.38 276552.00 0.0001381 38.20 Equity Common Stock, $0.00001 par value per share true 8400 1.02 8568.00 0.0001381 1.19 Equity Common Stock, $0.00001 par value per share true 125600 1.14 143184.00 0.0001381 19.78 Equity Common Stock, $0.00001 par value per share true 61000 1.32 80520.00 0.0001381 11.12 2546468.30 351.73 0.00 351.73 Pursuant to Rule 416 under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on August 29, 2025 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on September 30, 2025 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act , this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on October 31, 2025 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on November 28, 2025 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on December 31, 2025 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on January 30, 2026 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted February 27, 2026 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted March 31, 2026 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted April 30, 2026 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on May 29, 2026 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on June 30, 2026 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award. Pursuant to Rule 416 under the Securities Act of 1933, this Registration Statement also covers such additional securities that may from time to time be offered or issued to prevent dilution from stock splits, stock dividends or similar transactions. Consists of shares issuable under new hire inducement stock option awards granted on July 31, 2026 in accordance with Nasdaq Listing Rule 5635(c)(4). Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the applicable inducement stock option award.