Disposal Group, Including Discontinued Operation, Consideration, Royalty Release Fee

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- Definition

Increase (Decrease) In Royalty Financing Liabilities

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No definition available.

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- Definition

Interest Paid, Royalty Financing Liabilities

+ References

No definition available.

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- Definition

Royalties Monetizations [Line Items]

+ References

No definition available.

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- Definition

Royalty Purchase Agreement, Royalties Paid And Payable

+ References

No definition available.

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- Definition

The percentage of annual net sales for royalties to be paid under the royalty purchase agreement.

+ References

No definition available.

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- Definition

he percentage of annual net sales of royalties to be paid under the royalty purchase agreement if sales are less than specified.

+ References

No definition available.

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- Definition

The percentage of net sales in key territories for royalties to be paid under the royalty purchase agreement.

+ References

No definition available.

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- Definition

The percentage of annual net sales in other markets of royalties to be paid under the royalty purchase agreement.

+ References

No definition available.

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- Definition

The percentage of the purchase price under the royalty purchase agreement.

+ References

No definition available.

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- Definition

The percentage of sublicense revenue in other markets of royalties to be paid under the royalty purchase agreement.

+ References

No definition available.

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- Definition

The amount of the purchase price under the royalty purchase agreement.

+ References

No definition available.

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- Definition

Information on the amount of the common stock premium.

+ References

No definition available.

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- Definition

The cash inflow during the period from additional borrowings in aggregate debt. Includes proceeds from short-term and long-term debt.

+ References

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- Definition

Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise.

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Royalty Financing Obligations - Narrative (Details) - USD ($) $ in Thousands				3 Months Ended		6 Months Ended
	Oct. 01, 2025	Nov. 19, 2021	Dec. 07, 2020	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
Royalties Monetizations [Line Items]
Reduction to royalty financing obligation						$ 26,788	$ 36,921
Royalty expenses				$ 218,250	$ 163,353	374,663	308,887
Interest paid, royalty financing obligations				18,318	22,372	26,788	36,921
Disposal Group, Disposed of by Sale, Not Discontinued Operations \| BioCryst Ireland
Royalties Monetizations [Line Items]
Royalty release fee	$ 15,000
Reduction to royalty financing obligation	15,500
ORLADEYO
Royalties Monetizations [Line Items]
Royalty expenses				158,202	$ 156,837	306,549	$ 291,080
RPI 2019 Intermediate Finance Trust
Royalties Monetizations [Line Items]
Shares issued, common stock, premium		$ 4,269
RPI 2019 Intermediate Finance Trust \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets			20.00%
RPI 2019 Intermediate Finance Trust \| Annual Net Sales Under $350,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in key territories			8.75%
RPI 2019 Intermediate Finance Trust \| Annual Net Sales Between $350,000 and $550,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in key territories			2.75%
RPI 2019 Intermediate Finance Trust \| Annual Net Sales Over $550,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in key territories			0.00%
RPI 2019 Intermediate Finance Trust \| Annual Net Sales Under $150,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in other markets			20.00%
RPI 2019 Intermediate Finance Trust \| Annual Net Sales Between $150,000 and $230,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in other markets			10.00%
RPI 2019 Intermediate Finance Trust \| Annual Net Sales Over $230,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in other markets			0.00%
RPI 2019 Intermediate Finance Trust \| Future Royalties Payable
Royalties Monetizations [Line Items]
Proceeds from issuance of debt			$ 125,000
RPI 2021 and 2020 Intermediate Finance Trust \| Future Royalties Payable
Royalties Monetizations [Line Items]
Proceeds from issuance of debt		$ 150,000
OMERS Capital Markets \| Disposal Group, Disposed of by Sale, Not Discontinued Operations \| BioCryst Ireland
Royalties Monetizations [Line Items]
Royalty release fee	$ 500
OMERS Capital Markets \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets		20.00%
Royalty purchase agreement, royalties, percentage of annual net sales in other markets		10.00%
Royalty purchase agreement, royalties, purchase price, amount		$ 150,000
Royalty purchase agreement, royalties, percentage of purchase price		155.00%
Royalty purchase agreement, royalties paid and payable				120,694		120,694
OMERS Capital Markets \| Annual Net Sales Under $350,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales		7.50%
Royalty purchase agreement, royalties, percentage of annual net sales, based on reduction in sales		10.00%
OMERS Capital Markets \| Annual Net Sales Between $350,000 and $550,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales		6.00%
Royalty purchase agreement, royalties, percentage of annual net sales, based on reduction in sales		3.00%
OMERS Capital Markets \| Annual Net Sales Over $550,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales		0.00%
Royalty purchase agreement, royalties, percentage of annual net sales, based on reduction in sales		0.00%
OMERS Capital Markets \| Annual Net Sales Under $150,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets		20.00%
OMERS Capital Markets \| Annual Net Sales Between $150,000 and $230,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets		10.00%
OMERS Capital Markets \| Annual Net Sales Over $230,000 \| ORLADEYO
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets		0.00%
The 2021 RPI Royalty Purchase Agreement \| Annual Net Sales Under $350,000
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in key territories		0.75%
The 2021 RPI Royalty Purchase Agreement \| Annual Net Sales Between $350,000 and $550,000
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in key territories		1.75%
The 2021 RPI Royalty Purchase Agreement \| Annual Net Sales Over $550,000
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in other markets		0.00%
The 2021 RPI Royalty Purchase Agreement \| Annual Net Sales Under $150,000
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets		3.00%
The 2021 RPI Royalty Purchase Agreement \| Annual Net Sales Between $150,000 and $230,000
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets		2.00%
The 2021 RPI Royalty Purchase Agreement \| Annual Net Sales Over $230,000
Royalties Monetizations [Line Items]
Royalty purchase agreement, royalties, percentage of annual net sales in other markets		0.00%
BioCryst Ireland
Royalties Monetizations [Line Items]
Royalty expenses				$ 2,873		$ 5,889