v3.26.1
Significant Accounting Policies and Concentrations of Risk (Details)
3 Months Ended 6 Months Ended
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2026
USD ($)
segment
Jun. 30, 2025
USD ($)
Dec. 31, 2025
USD ($)
Significant Accounting Policies and Concentration of Risk [Line Items]          
Number of reportable segments | segment     1    
Number of operating segments | segment     1    
Restricted cash $ 1,412,000   $ 1,412,000   $ 1,601,000
Long-term investment maturity, minimum (in years)     12 months    
Reclassification from accumulated other comprehensive income, current period, before tax $ 0 $ 0 $ 0 $ 0  
Revenue Benchmark | Product Concentration Risk | ORLADEYO          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Revenue percentage 97.00% 86.00% 95.00% 85.00%  
Computer Equipment          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Property, plant and equipment, useful life (in years) 3 years   3 years    
Laboratory Equipment, Office Equipment and Software          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Property, plant and equipment, useful life (in years) 5 years   5 years    
Furniture and Fixtures          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Property, plant and equipment, useful life (in years) 5 years   5 years    
Maximum          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Maturity period of high quality marketable securities (in years)     2 years    
Average maturity period of high quality marketable securities (in months)     12 months    
Maturity period of short term investment (in months)     12 months    
Letter of Credit          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Birmingham lease restricted cash $ 933,000   $ 933,000   1,400,000
Collateral for Credit          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Birmingham lease restricted cash $ 933,000   $ 933,000   $ 1,400,000