Derivative instruments - Schedule of Cross-Currency Swaps (Details) £ in Millions, $ in Millions	Jun. 30, 2026 USD ($)	Jun. 30, 2026 GBP (£)
5.50% £475 million notes due 2026 (5.50% 2026 pound sterling Notes) \| Cross-currency swap contracts \| Cash flow hedge
Derivative [Line Items]
Notional amounts	$ 747	£ 475
5.50% £475 million notes due 2026 (5.50% 2026 pound sterling Notes) \| Cross-currency swap contracts \| Cash flow hedge \| United States of America, Dollars
Derivative [Line Items]
Interest rates	6.00%	6.00%
5.50% £475 million notes due 2026 (5.50% 2026 pound sterling Notes) \| Cross-currency swap contracts \| Cash flow hedge \| United Kingdom, Pounds
Derivative [Line Items]
Interest rates	5.50%	5.50%
5.50% £475 million notes due 2026 (5.50% 2026 pound sterling Notes) \| Notes
Derivative [Line Items]
Interest rate, stated percentage	5.50%	5.50%
4.00% £700 million notes due 2029 (4.00% 2029 pound sterling Notes) \| Cross-currency swap contracts \| Cash flow hedge
Derivative [Line Items]
Notional amounts	$ 1,111	£ 700
4.00% £700 million notes due 2029 (4.00% 2029 pound sterling Notes) \| Cross-currency swap contracts \| Cash flow hedge \| United States of America, Dollars
Derivative [Line Items]
Interest rates	4.70%	4.70%
4.00% £700 million notes due 2029 (4.00% 2029 pound sterling Notes) \| Cross-currency swap contracts \| Cash flow hedge \| United Kingdom, Pounds
Derivative [Line Items]
Interest rates	4.00%	4.00%
4.00% £700 million notes due 2029 (4.00% 2029 pound sterling Notes) \| Notes
Derivative [Line Items]
Interest rate, stated percentage	4.00%	4.00%

Contractual interest rate for funds borrowed, under the debt agreement.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 942
-SubTopic 210
-Name Accounting Standards Codification
-Section S45
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147477657/942-210-S45-1

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 942
-SubTopic 210
-Name Accounting Standards Codification
-Section S50
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478478/942-210-S50-1

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 942
-SubTopic 210
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.9-03(16))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478546/942-210-S99-1

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(22)(a)(1))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

Reference 5: http://www.xbrl.org/2003/role/disclosureRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S50
-Paragraph 9
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480657/210-10-S50-9

Reference 6: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1B
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481139/470-20-50-1B

+ Details

Name:	us-gaap_DebtInstrumentInterestRateStatedPercentage
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Fixed interest rate related to the interest rate derivative.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 815
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 5
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480434/815-10-50-5

+ Details

Name:	us-gaap_DerivativeFixedInterestRate
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 815
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 5A
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480434/815-10-50-5A

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 18
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481112/505-10-50-18

Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 815
-SubTopic 20
-Name Accounting Standards Codification
-Section 25
-Paragraph 6A
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480682/815-20-25-6A

+ Details

Name:	us-gaap_DerivativeLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Nominal or face amount used to calculate payment on derivative.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 815
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1A
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480434/815-10-50-1A

Reference 2: http://www.xbrl.org/2003/role/exampleRef
-Topic 815
-SubTopic 10
-Name Accounting Standards Codification
-Section 55
-Paragraph 181
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480401/815-10-55-181

Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 815
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1B
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480434/815-10-50-1B

+ Details

Name:	us-gaap_DerivativeNotionalAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	na
Period Type:	instant

- Details

Name:	us-gaap_DebtInstrumentAxis=amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DerivativeInstrumentRiskAxis=amgn_CrossCurrencySwapContractsMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis=us-gaap_CashFlowHedgingMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_CurrencyAxis=currency_USD
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_CurrencyAxis=currency_GBP
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_LongtermDebtTypeAxis=us-gaap_NotesPayableToBanksMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=amgn_FourPointPoundSterlingNotesDue2029Member
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type: