<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019f04d0-8d9c-72ec-8457-b69d006ddebe,g:1c537bd1-eadb-4df3-9361-8d7b0b355877-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member"/>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/CondensedConsolidatedStatementsofChangesinEquity" xlink:type="simple" xlink:href="cwk-20260630.xsd#CondensedConsolidatedStatementsofChangesinEquity"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/CondensedConsolidatedStatementsofChangesinEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_019f04d0-8eef-77ac-9ecb-a8dc910c7f3b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_019f04d0-8eef-77c6-84c2-a61c111ee5e9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_019f04d0-8eef-77ac-9ecb-a8dc910c7f3b" xlink:to="loc_us-gaap_StatementTable_019f04d0-8eef-77c6-84c2-a61c111ee5e9" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8eef-755c-aef1-a0951f751cf7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_019f04d0-8eef-77c6-84c2-a61c111ee5e9" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8eef-755c-aef1-a0951f751cf7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f04d0-8eef-755c-aef1-a0951f751cf7_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8eef-755c-aef1-a0951f751cf7" xlink:to="loc_us-gaap_EquityComponentDomain_019f04d0-8eef-755c-aef1-a0951f751cf7_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f04d0-8eef-7a76-b408-a5e4305234a9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8eef-755c-aef1-a0951f751cf7" xlink:to="loc_us-gaap_EquityComponentDomain_019f04d0-8eef-7a76-b408-a5e4305234a9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ParentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_019f04d0-8eef-7a76-b408-a5e4305234a9" xlink:to="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_019f04d0-8eef-7a40-9cdc-59eb6019b12c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:to="loc_us-gaap_CommonStockMember_019f04d0-8eef-7a40-9cdc-59eb6019b12c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_019f04d0-8eef-72fd-9eb0-387c8b76a676" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_019f04d0-8eef-72fd-9eb0-387c8b76a676" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_019f04d0-8eef-7735-bb4c-d248642038c7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetainedEarningsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:to="loc_us-gaap_RetainedEarningsMember_019f04d0-8eef-7735-bb4c-d248642038c7" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_019f04d0-8eef-7574-9184-99108a09ab8a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_019f04d0-8eef-7574-9184-99108a09ab8a" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_019f04d0-8eef-70ac-83d5-4fde1c49e133" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedTranslationAdjustmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_019f04d0-8eef-70ac-83d5-4fde1c49e133" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_019f04d0-8eef-7c09-9e45-d8249f9b26c9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:to="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_019f04d0-8eef-7c09-9e45-d8249f9b26c9" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_019f04d0-8eef-7c63-b426-feed8e3436f3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ParentMember_019f04d0-8eef-7df4-8731-6aeed4fa0e68" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_019f04d0-8eef-7c63-b426-feed8e3436f3" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoncontrollingInterestMember_019f04d0-8eef-7844-bc9e-74e28290663c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NoncontrollingInterestMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_019f04d0-8eef-7a76-b408-a5e4305234a9" xlink:to="loc_us-gaap_NoncontrollingInterestMember_019f04d0-8eef-7844-bc9e-74e28290663c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_019f04d0-8eef-77ac-9ecb-a8dc910c7f3b" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_019f04d0-8eef-750e-801a-d779143c1285" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SharesOutstanding"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_SharesOutstanding_019f04d0-8eef-750e-801a-d779143c1285" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_019f04d0-8eef-7c93-b5c3-f7815f6e83e0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_019f04d0-8eef-7c93-b5c3-f7815f6e83e0" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019f04d0-8eef-7b18-963f-4a43361f5685" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_NetIncomeLoss_019f04d0-8eef-7b18-963f-4a43361f5685" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_019f04d0-8eef-75ee-80a0-d064de148dd3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_019f04d0-8eef-75ee-80a0-d064de148dd3" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_019f04d0-8eef-78f3-ad31-b987cb82139b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_019f04d0-8eef-78f3-ad31-b987cb82139b" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_019f04d0-8eef-7f4c-8be7-92f3e65f697a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_019f04d0-8eef-7f4c-8be7-92f3e65f697a" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019f04d0-8eef-782a-a997-67657a436aa0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019f04d0-8eef-782a-a997-67657a436aa0" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_019f04d0-8eef-7688-b1d0-2897c7926b68" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_019f04d0-8eef-7688-b1d0-2897c7926b68" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentExcludingRedemptionsOrPurchaseOfInterestsNetOfTax_019f04d0-8eef-760a-9e6d-ceb9fd926ba4" xlink:href="cwk-20260630.xsd#cwk_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentExcludingRedemptionsOrPurchaseOfInterestsNetOfTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_cwk_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentExcludingRedemptionsOrPurchaseOfInterestsNetOfTax_019f04d0-8eef-760a-9e6d-ceb9fd926ba4" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_OtherComprehensiveIncomeLossDefinedBenefitPlanAdjustmentNetTax_019f04d0-8eef-7b2b-b589-cb5b0b3ec2db" xlink:href="cwk-20260630.xsd#cwk_OtherComprehensiveIncomeLossDefinedBenefitPlanAdjustmentNetTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_cwk_OtherComprehensiveIncomeLossDefinedBenefitPlanAdjustmentNetTax_019f04d0-8eef-7b2b-b589-cb5b0b3ec2db" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityOther_019f04d0-8eef-7439-82e8-cee1316d4368" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquityOther"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_019f04d0-8eef-73e0-9d60-6db94c3533e6" xlink:to="loc_us-gaap_StockholdersEquityOther_019f04d0-8eef-7439-82e8-cee1316d4368" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_019f04d0-8eef-799a-8a79-8d30b64df1d4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_019f04d0-8eef-7463-acc5-fa84eea1c3b1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/SegmentDataScheduleofSummarizedFinancialInformationbySegmentDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#SegmentDataScheduleofSummarizedFinancialInformationbySegmentDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/SegmentDataScheduleofSummarizedFinancialInformationbySegmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingInformationLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_019f04d0-8eef-7b68-aff3-df0af599f594" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_019f04d0-8eef-7b68-aff3-df0af599f594" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-7060-bf82-12f81d079449" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_019f04d0-8eef-7b68-aff3-df0af599f594" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-7060-bf82-12f81d079449" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_019f04d0-8eef-7060-bf82-12f81d079449_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-7060-bf82-12f81d079449" xlink:to="loc_us-gaap_SegmentDomain_019f04d0-8eef-7060-bf82-12f81d079449_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_019f04d0-8eef-7fd6-bc93-f058be152435" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-7060-bf82-12f81d079449" xlink:to="loc_us-gaap_SegmentDomain_019f04d0-8eef-7fd6-bc93-f058be152435" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AmericasSegmentMember_019f04d0-8eef-7418-bea7-7511ceb5e4fd" xlink:href="cwk-20260630.xsd#cwk_AmericasSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8eef-7fd6-bc93-f058be152435" xlink:to="loc_cwk_AmericasSegmentMember_019f04d0-8eef-7418-bea7-7511ceb5e4fd" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_EuropeTheMiddleEastAndAfricaSegmentMember_019f04d0-8eef-7caf-b12c-fe376587edce" xlink:href="cwk-20260630.xsd#cwk_EuropeTheMiddleEastAndAfricaSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8eef-7fd6-bc93-f058be152435" xlink:to="loc_cwk_EuropeTheMiddleEastAndAfricaSegmentMember_019f04d0-8eef-7caf-b12c-fe376587edce" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AsiaPacificSegmentMember_019f04d0-8eef-7e4b-9b23-42ec61a064b5" xlink:href="cwk-20260630.xsd#cwk_AsiaPacificSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8eef-7fd6-bc93-f058be152435" xlink:to="loc_cwk_AsiaPacificSegmentMember_019f04d0-8eef-7e4b-9b23-42ec61a064b5" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019f04d0-8eef-7d50-a743-5ab13561d7bf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019f04d0-8eef-7d50-a743-5ab13561d7bf" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_GrossContractCosts_019f04d0-8eef-7317-9c49-61086ef50939" xlink:href="cwk-20260630.xsd#cwk_GrossContractCosts"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_cwk_GrossContractCosts_019f04d0-8eef-7317-9c49-61086ef50939" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostDirectLabor_019f04d0-8eef-7cd7-b619-b6c51dff2f46" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostDirectLabor"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_us-gaap_CostDirectLabor_019f04d0-8eef-7cd7-b619-b6c51dff2f46" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_CostsDirectOther_019f04d0-8eef-772d-8362-0360d10a5f41" xlink:href="cwk-20260630.xsd#cwk_CostsDirectOther"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_cwk_CostsDirectOther_019f04d0-8eef-772d-8362-0360d10a5f41" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSoldOverhead_019f04d0-8eef-7326-83cb-463cee480c76" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServicesSoldOverhead"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSoldOverhead_019f04d0-8eef-7326-83cb-463cee480c76" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_OtherIndirectAndOverheadCosts_019f04d0-8eef-7d99-8073-416306910c9a" xlink:href="cwk-20260630.xsd#cwk_OtherIndirectAndOverheadCosts"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_cwk_OtherIndirectAndOverheadCosts_019f04d0-8eef-7d99-8073-416306910c9a" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingOtherItemAmount_019f04d0-8eef-7a2d-9f23-6af159f1bf3a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingOtherItemAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_us-gaap_SegmentReportingOtherItemAmount_019f04d0-8eef-7a2d-9f23-6af159f1bf3a" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_IncomeLossFromContinuingOperationsBeforeInterestTaxesDepreciationAndAmortization_019f04d0-8eef-71a8-918c-0dc596d080ed" xlink:href="cwk-20260630.xsd#cwk_IncomeLossFromContinuingOperationsBeforeInterestTaxesDepreciationAndAmortization"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_019f04d0-8eef-7849-b013-2f80608cbeed" xlink:to="loc_cwk_IncomeLossFromContinuingOperationsBeforeInterestTaxesDepreciationAndAmortization_019f04d0-8eef-71a8-918c-0dc596d080ed" xlink:type="arc" order="7"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/EarningsPerShareDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#EarningsPerShareDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/EarningsPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDilutedLineItems_019f04d0-8eef-7f2e-ba54-357edbd0b18e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareDilutedLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareDilutedByCommonClassTable_019f04d0-8eef-711c-a459-8cbdcade3218" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfEarningsPerShareDilutedByCommonClassTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_EarningsPerShareDilutedLineItems_019f04d0-8eef-7f2e-ba54-357edbd0b18e" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareDilutedByCommonClassTable_019f04d0-8eef-711c-a459-8cbdcade3218" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_019f04d0-8eef-776b-9dd2-f806be378e6d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AwardTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEarningsPerShareDilutedByCommonClassTable_019f04d0-8eef-711c-a459-8cbdcade3218" xlink:to="loc_us-gaap_AwardTypeAxis_019f04d0-8eef-776b-9dd2-f806be378e6d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_019f04d0-8eef-776b-9dd2-f806be378e6d_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_019f04d0-8eef-776b-9dd2-f806be378e6d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_019f04d0-8eef-776b-9dd2-f806be378e6d_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_019f04d0-8eef-762d-aa9c-78424343681d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_019f04d0-8eef-776b-9dd2-f806be378e6d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_019f04d0-8eef-762d-aa9c-78424343681d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_019f04d0-8eef-7b0c-b463-5cb12b380d14" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_019f04d0-8eef-762d-aa9c-78424343681d" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_019f04d0-8eef-7b0c-b463-5cb12b380d14" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasicAbstract_019f04d0-8eef-73c0-a61a-1882cd900992" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareBasicAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareDilutedLineItems_019f04d0-8eef-7f2e-ba54-357edbd0b18e" xlink:to="loc_us-gaap_EarningsPerShareBasicAbstract_019f04d0-8eef-73c0-a61a-1882cd900992" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019f04d0-8eef-75ed-a078-10ff22d5bd7c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_019f04d0-8eef-73c0-a61a-1882cd900992" xlink:to="loc_us-gaap_NetIncomeLoss_019f04d0-8eef-75ed-a078-10ff22d5bd7c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_019f04d0-8eef-7590-bf54-e5f7e81d53a8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_019f04d0-8eef-73c0-a61a-1882cd900992" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_019f04d0-8eef-7590-bf54-e5f7e81d53a8" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_019f04d0-8eef-743c-ac68-59212b92e2dd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_019f04d0-8eef-73c0-a61a-1882cd900992" xlink:to="loc_us-gaap_EarningsPerShareBasic_019f04d0-8eef-743c-ac68-59212b92e2dd" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDilutedAbstract_019f04d0-8eef-768a-963c-bfd3fc0abcde" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareDilutedAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareDilutedLineItems_019f04d0-8eef-7f2e-ba54-357edbd0b18e" xlink:to="loc_us-gaap_EarningsPerShareDilutedAbstract_019f04d0-8eef-768a-963c-bfd3fc0abcde" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019f04d0-8eef-7b46-962b-ee937a9e19e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_019f04d0-8eef-78e2-974d-ff3ad3fda4a1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019f04d0-8eef-742c-bdad-1f0bca400e9d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_019f04d0-8eef-768a-963c-bfd3fc0abcde" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019f04d0-8eef-742c-bdad-1f0bca400e9d" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019f04d0-8eef-72d6-8626-f5fe22bd99d1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_019f04d0-8eef-768a-963c-bfd3fc0abcde" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019f04d0-8eef-72d6-8626-f5fe22bd99d1" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_019f04d0-8eef-70d0-b006-80a8f316efe1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareDilutedAbstract_019f04d0-8eef-768a-963c-bfd3fc0abcde" xlink:to="loc_us-gaap_EarningsPerShareDiluted_019f04d0-8eef-70d0-b006-80a8f316efe1" xlink:type="arc" order="5"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/RevenueScheduleofDisaggregationofRevenueDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#RevenueScheduleofDisaggregationofRevenueDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/RevenueScheduleofDisaggregationofRevenueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_019f04d0-8eef-7786-82f6-a41a56e2f296" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_019f04d0-8eef-77ed-a966-2d81f947d802" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_019f04d0-8eef-7786-82f6-a41a56e2f296" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_019f04d0-8eef-77ed-a966-2d81f947d802" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_019f04d0-8eef-7d3d-a2e4-340171d5b94f" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_019f04d0-8eef-77ed-a966-2d81f947d802" xlink:to="loc_srt_ProductOrServiceAxis_019f04d0-8eef-7d3d-a2e4-340171d5b94f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7d3d-a2e4-340171d5b94f_default" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_019f04d0-8eef-7d3d-a2e4-340171d5b94f" xlink:to="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7d3d-a2e4-340171d5b94f_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7954-b316-3fd5e156c314" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_019f04d0-8eef-7d3d-a2e4-340171d5b94f" xlink:to="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7954-b316-3fd5e156c314" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ServiceMember_019f04d0-8eef-79b9-864c-20ac7ab4496f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ServiceMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7954-b316-3fd5e156c314" xlink:to="loc_us-gaap_ServiceMember_019f04d0-8eef-79b9-864c-20ac7ab4496f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_LeasingServiceMember_019f04d0-8eef-7a5b-83f8-44d029f05205" xlink:href="cwk-20260630.xsd#cwk_LeasingServiceMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7954-b316-3fd5e156c314" xlink:to="loc_cwk_LeasingServiceMember_019f04d0-8eef-7a5b-83f8-44d029f05205" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_CapitalMarketsServiceMember_019f04d0-8eef-784c-9825-83e65581a1f1" xlink:href="cwk-20260630.xsd#cwk_CapitalMarketsServiceMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7954-b316-3fd5e156c314" xlink:to="loc_cwk_CapitalMarketsServiceMember_019f04d0-8eef-784c-9825-83e65581a1f1" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_ValuationAndOtherServiceMember_019f04d0-8eef-7e04-9e87-793f36a91a64" xlink:href="cwk-20260630.xsd#cwk_ValuationAndOtherServiceMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_019f04d0-8eef-7954-b316-3fd5e156c314" xlink:to="loc_cwk_ValuationAndOtherServiceMember_019f04d0-8eef-7e04-9e87-793f36a91a64" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-74fb-8887-74af329992a1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_019f04d0-8eef-77ed-a966-2d81f947d802" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-74fb-8887-74af329992a1" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_019f04d0-8eef-74fb-8887-74af329992a1_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-74fb-8887-74af329992a1" xlink:to="loc_us-gaap_SegmentDomain_019f04d0-8eef-74fb-8887-74af329992a1_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_019f04d0-8eef-76c9-918d-f8c1de7c7cca" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8eef-74fb-8887-74af329992a1" xlink:to="loc_us-gaap_SegmentDomain_019f04d0-8eef-76c9-918d-f8c1de7c7cca" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AmericasSegmentMember_019f04d0-8eef-72e4-9a81-b5bcfd7cde7c" xlink:href="cwk-20260630.xsd#cwk_AmericasSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8eef-76c9-918d-f8c1de7c7cca" xlink:to="loc_cwk_AmericasSegmentMember_019f04d0-8eef-72e4-9a81-b5bcfd7cde7c" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_EuropeTheMiddleEastAndAfricaSegmentMember_019f04d0-8eef-7feb-84d3-d1316df28cc7" xlink:href="cwk-20260630.xsd#cwk_EuropeTheMiddleEastAndAfricaSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8eef-76c9-918d-f8c1de7c7cca" xlink:to="loc_cwk_EuropeTheMiddleEastAndAfricaSegmentMember_019f04d0-8eef-7feb-84d3-d1316df28cc7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AsiaPacificSegmentMember_019f04d0-8eef-772b-8bf6-85fe1badd182" xlink:href="cwk-20260630.xsd#cwk_AsiaPacificSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8eef-76c9-918d-f8c1de7c7cca" xlink:to="loc_cwk_AsiaPacificSegmentMember_019f04d0-8eef-772b-8bf6-85fe1badd182" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimingOfTransferOfGoodOrServiceAxis_019f04d0-8eef-7bba-b799-a2e962876970" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TimingOfTransferOfGoodOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_019f04d0-8eef-77ed-a966-2d81f947d802" xlink:to="loc_us-gaap_TimingOfTransferOfGoodOrServiceAxis_019f04d0-8eef-7bba-b799-a2e962876970" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_019f04d0-8eef-7bba-b799-a2e962876970_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TimingOfTransferOfGoodOrServiceDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_TimingOfTransferOfGoodOrServiceAxis_019f04d0-8eef-7bba-b799-a2e962876970" xlink:to="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_019f04d0-8eef-7bba-b799-a2e962876970_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_019f04d0-8eef-7a58-bc62-36dd5bf53336" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TimingOfTransferOfGoodOrServiceDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_TimingOfTransferOfGoodOrServiceAxis_019f04d0-8eef-7bba-b799-a2e962876970" xlink:to="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_019f04d0-8eef-7a58-bc62-36dd5bf53336" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransferredOverTimeMember_019f04d0-8eef-7d6d-9acd-6f2a64c56904" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TransferredOverTimeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_019f04d0-8eef-7a58-bc62-36dd5bf53336" xlink:to="loc_us-gaap_TransferredOverTimeMember_019f04d0-8eef-7d6d-9acd-6f2a64c56904" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransferredAtPointInTimeMember_019f04d0-8eef-77c2-af6e-f8b0ddd59054" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TransferredAtPointInTimeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_019f04d0-8eef-7a58-bc62-36dd5bf53336" xlink:to="loc_us-gaap_TransferredAtPointInTimeMember_019f04d0-8eef-77c2-af6e-f8b0ddd59054" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TransferredAtPointInTimeOrOverTimeMember_019f04d0-8eef-705a-ad55-d3d5df208325" xlink:href="cwk-20260630.xsd#cwk_TransferredAtPointInTimeOrOverTimeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_019f04d0-8eef-7a58-bc62-36dd5bf53336" xlink:to="loc_cwk_TransferredAtPointInTimeOrOverTimeMember_019f04d0-8eef-705a-ad55-d3d5df208325" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019f04d0-8eef-70f2-a737-f8615e5a6ee8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_019f04d0-8eef-7786-82f6-a41a56e2f296" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019f04d0-8eef-70f2-a737-f8615e5a6ee8" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/GoodwillandOtherIntangibleAssetsScheduleofGoodwillDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#GoodwillandOtherIntangibleAssetsScheduleofGoodwillDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/GoodwillandOtherIntangibleAssetsScheduleofGoodwillDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-74b8-a86f-c074dd6524fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GoodwillLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-7130-a4eb-be5eb2822b56" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfGoodwillTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-74b8-a86f-c074dd6524fc" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-7130-a4eb-be5eb2822b56" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8ef0-75c7-946e-329a477c6f76" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-7130-a4eb-be5eb2822b56" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8ef0-75c7-946e-329a477c6f76" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_019f04d0-8ef0-75c7-946e-329a477c6f76_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8ef0-75c7-946e-329a477c6f76" xlink:to="loc_us-gaap_SegmentDomain_019f04d0-8ef0-75c7-946e-329a477c6f76_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_019f04d0-8ef0-7b78-89ef-f26422a48198" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_019f04d0-8ef0-75c7-946e-329a477c6f76" xlink:to="loc_us-gaap_SegmentDomain_019f04d0-8ef0-7b78-89ef-f26422a48198" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AmericasSegmentMember_019f04d0-8ef0-7277-b148-a855b226b880" xlink:href="cwk-20260630.xsd#cwk_AmericasSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8ef0-7b78-89ef-f26422a48198" xlink:to="loc_cwk_AmericasSegmentMember_019f04d0-8ef0-7277-b148-a855b226b880" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_EuropeTheMiddleEastAndAfricaSegmentMember_019f04d0-8ef0-7233-b28f-296a809ef7f3" xlink:href="cwk-20260630.xsd#cwk_EuropeTheMiddleEastAndAfricaSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8ef0-7b78-89ef-f26422a48198" xlink:to="loc_cwk_EuropeTheMiddleEastAndAfricaSegmentMember_019f04d0-8ef0-7233-b28f-296a809ef7f3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AsiaPacificSegmentMember_019f04d0-8ef0-7f76-9310-a2032cc67511" xlink:href="cwk-20260630.xsd#cwk_AsiaPacificSegmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_019f04d0-8ef0-7b78-89ef-f26422a48198" xlink:to="loc_cwk_AsiaPacificSegmentMember_019f04d0-8ef0-7f76-9310-a2032cc67511" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillRollForward_019f04d0-8ef0-71ea-a6bc-baac26150bdf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GoodwillRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-74b8-a86f-c074dd6524fc" xlink:to="loc_us-gaap_GoodwillRollForward_019f04d0-8ef0-71ea-a6bc-baac26150bdf" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_019f04d0-8ef0-7a71-b27e-c730c837a951" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Goodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_019f04d0-8ef0-71ea-a6bc-baac26150bdf" xlink:to="loc_us-gaap_Goodwill_019f04d0-8ef0-7a71-b27e-c730c837a951" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_019f04d0-8ef0-7082-8a50-a1f22e6aa62c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GoodwillForeignCurrencyTranslationGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_019f04d0-8ef0-71ea-a6bc-baac26150bdf" xlink:to="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_019f04d0-8ef0-7082-8a50-a1f22e6aa62c" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_019f04d0-8ef0-778a-9bb3-5752c484d960" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Goodwill"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/GoodwillandOtherIntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#GoodwillandOtherIntangibleAssetsScheduleofIntangibleAssetsDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/GoodwillandOtherIntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GoodwillLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-799a-a813-035393df5f64" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfGoodwillTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-799a-a813-035393df5f64" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-72c2-9eb4-b21b7c4175a3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-799a-a813-035393df5f64" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-72c2-9eb4-b21b7c4175a3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-72c2-9eb4-b21b7c4175a3_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-72c2-9eb4-b21b7c4175a3" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-72c2-9eb4-b21b7c4175a3_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-787f-b813-49ebcb83f7e1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-72c2-9eb4-b21b7c4175a3" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-787f-b813-49ebcb83f7e1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TradeNamesMember_019f04d0-8ef0-7239-bc6b-e499a968e02c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TradeNamesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-787f-b813-49ebcb83f7e1" xlink:to="loc_us-gaap_TradeNamesMember_019f04d0-8ef0-7239-bc6b-e499a968e02c" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_019f04d0-8ef0-7b31-80c1-a6402cde1346" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-799a-a813-035393df5f64" xlink:to="loc_srt_RangeAxis_019f04d0-8ef0-7b31-80c1-a6402cde1346" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_019f04d0-8ef0-7b31-80c1-a6402cde1346_default" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_019f04d0-8ef0-7b31-80c1-a6402cde1346" xlink:to="loc_srt_RangeMember_019f04d0-8ef0-7b31-80c1-a6402cde1346_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_019f04d0-8ef0-7f95-870a-0edbdce21fe1" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_019f04d0-8ef0-7b31-80c1-a6402cde1346" xlink:to="loc_srt_RangeMember_019f04d0-8ef0-7f95-870a-0edbdce21fe1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_019f04d0-8ef0-754f-a8e2-6cdf1a84bfd7" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_019f04d0-8ef0-7f95-870a-0edbdce21fe1" xlink:to="loc_srt_MinimumMember_019f04d0-8ef0-754f-a8e2-6cdf1a84bfd7" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_019f04d0-8ef0-75e8-ab8e-c2ebb4ca82ca" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_019f04d0-8ef0-7f95-870a-0edbdce21fe1" xlink:to="loc_srt_MaximumMember_019f04d0-8ef0-75e8-ab8e-c2ebb4ca82ca" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-741d-896f-148ffd5dad59" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_019f04d0-8ef0-799a-a813-035393df5f64" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-741d-896f-148ffd5dad59" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-741d-896f-148ffd5dad59_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-741d-896f-148ffd5dad59" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-741d-896f-148ffd5dad59_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-7f6a-b33f-3d68bf95f1e7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_019f04d0-8ef0-741d-896f-148ffd5dad59" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-7f6a-b33f-3d68bf95f1e7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerRelationshipsMember_019f04d0-8ef0-791f-b75f-3be2f0bc6956" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CustomerRelationshipsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_019f04d0-8ef0-7f6a-b33f-3d68bf95f1e7" xlink:to="loc_us-gaap_CustomerRelationshipsMember_019f04d0-8ef0-791f-b75f-3be2f0bc6956" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_019f04d0-8ef0-77f7-8664-a5266f1ef96a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_019f04d0-8ef0-77f7-8664-a5266f1ef96a" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_019f04d0-8ef0-71be-8c31-a21720e4a66a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_019f04d0-8ef0-71be-8c31-a21720e4a66a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019f04d0-8ef0-725b-adf1-5687a156bb4d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019f04d0-8ef0-725b-adf1-5687a156bb4d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_019f04d0-8ef0-7acc-9933-1cf2fe572eb0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_019f04d0-8ef0-7acc-9933-1cf2fe572eb0" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019f04d0-8ef0-7b7e-ad75-0338fa0a56a1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019f04d0-8ef0-7b7e-ad75-0338fa0a56a1" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_019f04d0-8ef0-7a35-b462-7da200306e8f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019f04d0-8ef0-7a45-a2f6-8b8e8bbd7d91" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019f04d0-8ef0-7a45-a2f6-8b8e8bbd7d91" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019f04d0-8ef0-7c65-921f-67721f615d7a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_019f04d0-8ef0-795a-81a5-7fdbc99f5d0f" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019f04d0-8ef0-7c65-921f-67721f615d7a" xlink:type="arc" order="7"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/EquityMethodInvestmentsNarrativeDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#EquityMethodInvestmentsNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/EquityMethodInvestmentsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-74af-94c7-462dc11e4b9a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_019f04d0-8ef0-74aa-a412-637efb1e2687" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-74af-94c7-462dc11e4b9a" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_019f04d0-8ef0-74aa-a412-637efb1e2687" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7fc6-970a-e2e5dc7c5240" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_019f04d0-8ef0-74aa-a412-637efb1e2687" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7fc6-970a-e2e5dc7c5240" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7fc6-970a-e2e5dc7c5240_default" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_EquityMethodInvesteeNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7fc6-970a-e2e5dc7c5240" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7fc6-970a-e2e5dc7c5240_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7dfb-8041-534f0da80790" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_EquityMethodInvesteeNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7fc6-970a-e2e5dc7c5240" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7dfb-8041-534f0da80790" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_GreystoneJVMember_019f04d0-8ef0-7e0b-a676-f53718071f66" xlink:href="cwk-20260630.xsd#cwk_GreystoneJVMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7dfb-8041-534f0da80790" xlink:to="loc_cwk_GreystoneJVMember_019f04d0-8ef0-7e0b-a676-f53718071f66" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_CushmanWakefieldVankeServiceMember_019f04d0-8ef0-7699-8e23-fe8217cdb090" xlink:href="cwk-20260630.xsd#cwk_CushmanWakefieldVankeServiceMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7dfb-8041-534f0da80790" xlink:to="loc_cwk_CushmanWakefieldVankeServiceMember_019f04d0-8ef0-7699-8e23-fe8217cdb090" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_019f04d0-8ef0-768f-95f6-bb3edb7f64b1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-74af-94c7-462dc11e4b9a" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_019f04d0-8ef0-768f-95f6-bb3edb7f64b1" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RoyaltyIncomeNonoperating_019f04d0-8ef0-7b93-92a1-19a37210b764" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RoyaltyIncomeNonoperating"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-74af-94c7-462dc11e4b9a" xlink:to="loc_us-gaap_RoyaltyIncomeNonoperating_019f04d0-8ef0-7b93-92a1-19a37210b764" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_019f04d0-8ef0-76b0-88a8-6bc5fbfa852f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityMethodInvestmentDividendsOrDistributions"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-74af-94c7-462dc11e4b9a" xlink:to="loc_us-gaap_EquityMethodInvestmentDividendsOrDistributions_019f04d0-8ef0-76b0-88a8-6bc5fbfa852f" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOtherThanTemporaryImpairment_019fb025-3428-7746-adf2-77c33d445944" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityMethodInvestmentOtherThanTemporaryImpairment"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-74af-94c7-462dc11e4b9a" xlink:to="loc_us-gaap_EquityMethodInvestmentOtherThanTemporaryImpairment_019fb025-3428-7746-adf2-77c33d445944" xlink:type="arc" order="3"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/EquityMethodInvestmentsScheduleofEquityMethodInvestmentsDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#EquityMethodInvestmentsScheduleofEquityMethodInvestmentsDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/EquityMethodInvestmentsScheduleofEquityMethodInvestmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-70ef-b25e-ae902ba0091f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_019f04d0-8ef0-7216-9590-69bc72d6d3c7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-70ef-b25e-ae902ba0091f" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_019f04d0-8ef0-7216-9590-69bc72d6d3c7" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7b45-a723-07ac6c5dc6d9" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_019f04d0-8ef0-7216-9590-69bc72d6d3c7" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7b45-a723-07ac6c5dc6d9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7b45-a723-07ac6c5dc6d9_default" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_EquityMethodInvesteeNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7b45-a723-07ac6c5dc6d9" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7b45-a723-07ac6c5dc6d9_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7a06-96e2-fb0e641ee6fb" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_EquityMethodInvesteeNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7b45-a723-07ac6c5dc6d9" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7a06-96e2-fb0e641ee6fb" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_GreystoneJVMember_019f04d0-8ef0-7f6a-9f5d-25cc4bbbe8b5" xlink:href="cwk-20260630.xsd#cwk_GreystoneJVMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7a06-96e2-fb0e641ee6fb" xlink:to="loc_cwk_GreystoneJVMember_019f04d0-8ef0-7f6a-9f5d-25cc4bbbe8b5" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_OnewoJVMember_019f04d0-8ef0-7378-8600-450eeb53afa8" xlink:href="cwk-20260630.xsd#cwk_OnewoJVMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7a06-96e2-fb0e641ee6fb" xlink:to="loc_cwk_OnewoJVMember_019f04d0-8ef0-7378-8600-450eeb53afa8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherInvesteesMember_019f04d0-8ef0-76e8-94eb-74b410bbe17a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherInvesteesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7a06-96e2-fb0e641ee6fb" xlink:to="loc_us-gaap_OtherInvesteesMember_019f04d0-8ef0-76e8-94eb-74b410bbe17a" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestments_019f04d0-8ef0-7ee1-9156-c2502d81e6ea" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-70ef-b25e-ae902ba0091f" xlink:to="loc_us-gaap_EquityMethodInvestments_019f04d0-8ef0-7ee1-9156-c2502d81e6ea" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_019f04d0-8ef0-7b16-86bb-b299bc107367" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromEquityMethodInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_019f04d0-8ef0-70ef-b25e-ae902ba0091f" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_019f04d0-8ef0-7b16-86bb-b299bc107367" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesNarrativeDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#DerivativeFinancialInstrumentsandHedgingActivitiesNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7d61-81ba-7c4e16508dbb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7d61-81ba-7c4e16508dbb" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_019f91b4-d1d3-706d-9bba-41820c84ea71" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7d61-81ba-7c4e16508dbb" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_019f91b4-d1d3-706d-9bba-41820c84ea71" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f91b4-d1d3-706d-9bba-41820c84ea71_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f91b4-d1d3-706d-9bba-41820c84ea71" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f91b4-d1d3-706d-9bba-41820c84ea71_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f91b4-d1d3-7059-8490-2d9cc5537a03" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f91b4-d1d3-706d-9bba-41820c84ea71" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f91b4-d1d3-7059-8490-2d9cc5537a03" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_019f91b4-d1d3-776e-b943-8090cba4561b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f91b4-d1d3-7059-8490-2d9cc5537a03" xlink:to="loc_us-gaap_InterestRateSwapMember_019f91b4-d1d3-776e-b943-8090cba4561b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_InterestRateSwapExpiringAugust2027Member_019f91b4-d1d3-77e4-b202-7b3cc19a16d4" xlink:href="cwk-20260630.xsd#cwk_InterestRateSwapExpiringAugust2027Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InterestRateSwapMember_019f91b4-d1d3-776e-b943-8090cba4561b" xlink:to="loc_cwk_InterestRateSwapExpiringAugust2027Member_019f91b4-d1d3-77e4-b202-7b3cc19a16d4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_InterestRateSwapExpiringMay2028Member_019f91b4-d1d3-78b9-b33b-6a5c454824e1" xlink:href="cwk-20260630.xsd#cwk_InterestRateSwapExpiringMay2028Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InterestRateSwapMember_019f91b4-d1d3-776e-b943-8090cba4561b" xlink:to="loc_cwk_InterestRateSwapExpiringMay2028Member_019f91b4-d1d3-78b9-b33b-6a5c454824e1" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_InterestRateSwapExpiringJune292029Member_019f91b4-d1d3-7c9e-88a0-7b9659f7e83f" xlink:href="cwk-20260630.xsd#cwk_InterestRateSwapExpiringJune292029Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InterestRateSwapMember_019f91b4-d1d3-776e-b943-8090cba4561b" xlink:to="loc_cwk_InterestRateSwapExpiringJune292029Member_019f91b4-d1d3-7c9e-88a0-7b9659f7e83f" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_InterestRateSwapExpiringJune302029Member_019f91b4-d1d3-7ee3-90f5-22756990c171" xlink:href="cwk-20260630.xsd#cwk_InterestRateSwapExpiringJune302029Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InterestRateSwapMember_019f91b4-d1d3-776e-b943-8090cba4561b" xlink:to="loc_cwk_InterestRateSwapExpiringJune302029Member_019f91b4-d1d3-7ee3-90f5-22756990c171" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeForwardMember_019f91b4-edd2-779c-aa70-96ec1adaf281" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignExchangeForwardMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f91b4-d1d3-7059-8490-2d9cc5537a03" xlink:to="loc_us-gaap_ForeignExchangeForwardMember_019f91b4-edd2-779c-aa70-96ec1adaf281" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_019f91b4-d1d3-7cf3-a8df-21706bcd12b9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7d61-81ba-7c4e16508dbb" xlink:to="loc_us-gaap_HedgingDesignationAxis_019f91b4-d1d3-7cf3-a8df-21706bcd12b9" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_019f91b4-d1d3-7cf3-a8df-21706bcd12b9_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_019f91b4-d1d3-7cf3-a8df-21706bcd12b9" xlink:to="loc_us-gaap_HedgingDesignationDomain_019f91b4-d1d3-7cf3-a8df-21706bcd12b9_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_019f91b4-d1d3-7b58-8dd4-71c399245bd7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_019f91b4-d1d3-7cf3-a8df-21706bcd12b9" xlink:to="loc_us-gaap_HedgingDesignationDomain_019f91b4-d1d3-7b58-8dd4-71c399245bd7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_019f91b4-d1d3-73de-bff7-4fd9b8dd308b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_019f91b4-d1d3-7b58-8dd4-71c399245bd7" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_019f91b4-d1d3-73de-bff7-4fd9b8dd308b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_019f91b4-edd2-71bd-972a-302b81545a12" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NondesignatedMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_019f91b4-d1d3-7b58-8dd4-71c399245bd7" xlink:to="loc_us-gaap_NondesignatedMember_019f91b4-edd2-71bd-972a-302b81545a12" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f91b4-d1d3-76bd-b5e2-100c4c8a5458" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7d61-81ba-7c4e16508dbb" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f91b4-d1d3-76bd-b5e2-100c4c8a5458" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f91b4-d1d3-76bd-b5e2-100c4c8a5458_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f91b4-d1d3-76bd-b5e2-100c4c8a5458" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f91b4-d1d3-76bd-b5e2-100c4c8a5458_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f91b4-d1d3-79fd-ac9a-9c36451fe181" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f91b4-d1d3-76bd-b5e2-100c4c8a5458" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f91b4-d1d3-79fd-ac9a-9c36451fe181" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_019f91b4-d1d3-76dc-bc76-10b1493fa9a3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_019f91b4-d1d3-79fd-ac9a-9c36451fe181" xlink:to="loc_us-gaap_CashFlowHedgingMember_019f91b4-d1d3-76dc-bc76-10b1493fa9a3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_019f91b5-11fc-7452-b4fe-17aed35418a4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7d61-81ba-7c4e16508dbb" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_019f91b5-11fc-7452-b4fe-17aed35418a4" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_019f91b5-11fc-7452-b4fe-17aed35418a4_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_019f91b5-11fc-7452-b4fe-17aed35418a4" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_019f91b5-11fc-7452-b4fe-17aed35418a4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_019f91b5-11fc-7d78-b36a-4fb9bc4f2a2f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeAxis_019f91b5-11fc-7452-b4fe-17aed35418a4" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_019f91b5-11fc-7d78-b36a-4fb9bc4f2a2f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_019f91b5-11fc-7233-839d-cb754dfa6a3b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeDomain_019f91b5-11fc-7d78-b36a-4fb9bc4f2a2f" xlink:to="loc_us-gaap_ReclassificationOutOfAccumulatedOtherComprehensiveIncomeMember_019f91b5-11fc-7233-839d-cb754dfa6a3b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_019f91b5-11fc-780b-901c-d69c80d52ebe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7d61-81ba-7c4e16508dbb" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_019f91b5-11fc-780b-901c-d69c80d52ebe" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f91b5-11fc-780b-901c-d69c80d52ebe_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f91b5-11fc-780b-901c-d69c80d52ebe" xlink:to="loc_us-gaap_EquityComponentDomain_019f91b5-11fc-780b-901c-d69c80d52ebe_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f91b5-11fc-7872-ba11-4c130b941c27" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f91b5-11fc-780b-901c-d69c80d52ebe" xlink:to="loc_us-gaap_EquityComponentDomain_019f91b5-11fc-7872-ba11-4c130b941c27" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_019f91b5-11fc-74cc-b29c-c01bc25ef6b7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_019f91b5-11fc-7872-ba11-4c130b941c27" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_019f91b5-11fc-74cc-b29c-c01bc25ef6b7" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_DerivativeNumberOfNewInstrumentsHeld_019f91b4-d1d3-72b7-bfce-2d92a27e6ba3" xlink:href="cwk-20260630.xsd#cwk_DerivativeNumberOfNewInstrumentsHeld"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_cwk_DerivativeNumberOfNewInstrumentsHeld_019f91b4-d1d3-72b7-bfce-2d92a27e6ba3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNumberOfInstrumentsHeld_019f91b4-d1d3-7aeb-82ba-2d649af4749e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeNumberOfInstrumentsHeld"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_DerivativeNumberOfInstrumentsHeld_019f91b4-d1d3-7aeb-82ba-2d649af4749e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_019f91b4-d1d3-7efd-a92b-99691977b7a5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_DerivativeNotionalAmount_019f91b4-d1d3-7efd-a92b-99691977b7a5" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax_019f91b4-d1d3-785f-bbfd-37ed3945a7fd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax_019f91b4-d1d3-785f-bbfd-37ed3945a7fd" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_019f91b4-d1d3-7457-9309-ef04f93ccca9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_019f91b4-d1d3-7457-9309-ef04f93ccca9" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainOnDerivativeInstrumentsPretax_019f91b4-edd2-70ce-94c6-2d0684c2f285" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GainOnDerivativeInstrumentsPretax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_GainOnDerivativeInstrumentsPretax_019f91b4-edd2-70ce-94c6-2d0684c2f285" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_UnrealizedGainOnDerivativeInstrumentsPretax_019f91b4-edd2-7f42-b67e-53a15e0ee202" xlink:href="cwk-20260630.xsd#cwk_UnrealizedGainOnDerivativeInstrumentsPretax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_cwk_UnrealizedGainOnDerivativeInstrumentsPretax_019f91b4-edd2-7f42-b67e-53a15e0ee202" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossOnDerivativeInstrumentsPretax_019f91b4-edd2-73fa-b936-33be2198e19d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossOnDerivativeInstrumentsPretax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_LossOnDerivativeInstrumentsPretax_019f91b4-edd2-73fa-b936-33be2198e19d" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_UnrealizedLossOnDerivativeInstrumentsPretax_019f91b4-edd2-789c-bd44-b0e40500c2ea" xlink:href="cwk-20260630.xsd#cwk_UnrealizedLossOnDerivativeInstrumentsPretax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_cwk_UnrealizedLossOnDerivativeInstrumentsPretax_019f91b4-edd2-789c-bd44-b0e40500c2ea" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateCashFlowHedgeGainLossReclassifiedToEarningsNet_019f91b5-11fc-7599-bc69-f4e10b6ada02" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateCashFlowHedgeGainLossReclassifiedToEarningsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f91b4-d1d3-7c08-9a4c-485eb9000d03" xlink:to="loc_us-gaap_InterestRateCashFlowHedgeGainLossReclassifiedToEarningsNet_019f91b5-11fc-7599-bc69-f4e10b6ada02" xlink:type="arc" order="9"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofFairValueofDerivativesDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofFairValueofDerivativesDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofFairValueofDerivativesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:to="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-7029-b2a8-4c91c0e60781_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:to="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-7029-b2a8-4c91c0e60781_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:to="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_019f04d0-8ef0-723c-a112-cc825d1c9e89" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_019f04d0-8ef0-723c-a112-cc825d1c9e89" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_019f04d0-8ef0-73f9-aeda-659de2405593" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NondesignatedMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:to="loc_us-gaap_NondesignatedMember_019f04d0-8ef0-73f9-aeda-659de2405593" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7132-ae42-db5029b6fcf7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7132-ae42-db5029b6fcf7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-7011-8238-5a9fa23970de" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7132-ae42-db5029b6fcf7" xlink:to="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-7011-8238-5a9fa23970de" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_019f04d0-8ef0-7e51-af48-d21d82616099" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:to="loc_us-gaap_InterestRateSwapMember_019f04d0-8ef0-7e51-af48-d21d82616099" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeForwardMember_019f04d0-8ef0-7e58-96b2-ebb0b9e69f2f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignExchangeForwardMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:to="loc_us-gaap_ForeignExchangeForwardMember_019f04d0-8ef0-7e58-96b2-ebb0b9e69f2f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionLocationBalanceAxis_019f04d0-8ef0-7975-854c-013954147f0d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementOfFinancialPositionLocationBalanceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:to="loc_us-gaap_StatementOfFinancialPositionLocationBalanceAxis_019f04d0-8ef0-7975-854c-013954147f0d" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_019f04d0-8ef0-7572-8101-157c7ec76764" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeNotionalAmount_019f04d0-8ef0-7572-8101-157c7ec76764" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_019f04d0-8ef0-7d91-a42d-8879e705c9e1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_019f04d0-8ef0-7d91-a42d-8879e705c9e1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_019f04d0-8ef0-7a2e-b3f2-913cc6299821" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_019f04d0-8ef0-7a2e-b3f2-913cc6299821" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofFairValueofDerivativesDetails_1" xlink:type="simple" xlink:href="cwk-20260630.xsd#DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofFairValueofDerivativesDetails_1"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofFairValueofDerivativesDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:to="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-7029-b2a8-4c91c0e60781_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:to="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-7029-b2a8-4c91c0e60781_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingDesignationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_019f04d0-8ef0-7029-b2a8-4c91c0e60781" xlink:to="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_019f04d0-8ef0-723c-a112-cc825d1c9e89" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DesignatedAsHedgingInstrumentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_019f04d0-8ef0-723c-a112-cc825d1c9e89" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NondesignatedMember_019f04d0-8ef0-73f9-aeda-659de2405593" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NondesignatedMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_019f04d0-8ef0-706b-a2e3-c39e53418add" xlink:to="loc_us-gaap_NondesignatedMember_019f04d0-8ef0-73f9-aeda-659de2405593" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7132-ae42-db5029b6fcf7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-7f8c-8bbd-dd1265c1c4e2" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7132-ae42-db5029b6fcf7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-7011-8238-5a9fa23970de" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-7132-ae42-db5029b6fcf7" xlink:to="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-7011-8238-5a9fa23970de" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7289-bed0-f77edb22e1d0" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7a6a-8d0f-06a99d846b1f" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_019f04d0-8ef0-7e51-af48-d21d82616099" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:to="loc_us-gaap_InterestRateSwapMember_019f04d0-8ef0-7e51-af48-d21d82616099" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeForwardMember_019f04d0-8ef0-7e58-96b2-ebb0b9e69f2f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignExchangeForwardMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7cf7-a96e-a550399a1747" xlink:to="loc_us-gaap_ForeignExchangeForwardMember_019f04d0-8ef0-7e58-96b2-ebb0b9e69f2f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeNotionalAmount_019f04d0-8ef0-7572-8101-157c7ec76764" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeNotionalAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeNotionalAmount_019f04d0-8ef0-7572-8101-157c7ec76764" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_019f04d0-8ef0-7d91-a42d-8879e705c9e1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_019f04d0-8ef0-7d91-a42d-8879e705c9e1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_019f04d0-8ef0-7a2e-b3f2-913cc6299821" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-7205-9a89-cdacf63d3a71" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_019f04d0-8ef0-7a2e-b3f2-913cc6299821" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofEffectofDerivativesAsHedgesNetofApplicableIncomeTaxesDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofEffectofDerivativesAsHedgesNetofApplicableIncomeTaxesDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofEffectofDerivativesAsHedgesNetofApplicableIncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-78fd-95c3-d4b748de7645" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-78fd-95c3-d4b748de7645" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-700e-9145-e5ef62f0076f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-78fd-95c3-d4b748de7645" xlink:to="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-700e-9145-e5ef62f0076f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-70c0-a823-ccf3b5c1450e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:to="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-70c0-a823-ccf3b5c1450e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-7d69-b436-b0486f8c82e6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:to="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-7d69-b436-b0486f8c82e6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AccumulatedGainLossNetCashFlowHedgeParentExclusiveOfImpairmentMember_019f04d0-8ef0-7879-a849-ba7836036626" xlink:href="cwk-20260630.xsd#cwk_AccumulatedGainLossNetCashFlowHedgeParentExclusiveOfImpairmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-7d69-b436-b0486f8c82e6" xlink:to="loc_cwk_AccumulatedGainLossNetCashFlowHedgeParentExclusiveOfImpairmentMember_019f04d0-8ef0-7879-a849-ba7836036626" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7705-acf7-037fc8e3b81b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7705-acf7-037fc8e3b81b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateContractMember_019f04d0-8ef0-7f1a-95a4-8b032342a803" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateContractMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7705-acf7-037fc8e3b81b" xlink:to="loc_us-gaap_InterestRateContractMember_019f04d0-8ef0-7f1a-95a4-8b032342a803" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeBalanceAxis_019f04d0-8ef0-7535-8dd6-151d571c52f8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeBalanceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:to="loc_us-gaap_OtherComprehensiveIncomeBalanceAxis_019f04d0-8ef0-7535-8dd6-151d571c52f8" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AOCIAttributableToParentNetOfTaxRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019f04d0-8ef0-7f72-9eb4-4eb72a37c877" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:to="loc_us-gaap_StockholdersEquity_019f04d0-8ef0-7f72-9eb4-4eb72a37c877" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019f04d0-8ef0-7826-bcd0-65bc1a63e9a5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019f04d0-8ef0-7826-bcd0-65bc1a63e9a5" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax_019f04d0-8ef0-7a2d-8bc4-9b6edd9c82a5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax_019f04d0-8ef0-7a2d-8bc4-9b6edd9c82a5" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019f04d0-8ef0-7284-af7d-1fab33bd4fe7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_019f04d0-8ef0-768c-8db1-48f55d2c60ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_019f04d0-8ef0-768c-8db1-48f55d2c60ff" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_019f04d0-8ef0-79a1-9f65-d583d201363e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationFromAociCurrentPeriodTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_019f04d0-8ef0-79a1-9f65-d583d201363e" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofEffectofDerivativesAsHedgesNetofApplicableIncomeTaxesDetails_1" xlink:type="simple" xlink:href="cwk-20260630.xsd#DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofEffectofDerivativesAsHedgesNetofApplicableIncomeTaxesDetails_1"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/DerivativeFinancialInstrumentsandHedgingActivitiesScheduleofEffectofDerivativesAsHedgesNetofApplicableIncomeTaxesDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-78fd-95c3-d4b748de7645" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_HedgingRelationshipDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_019f04d0-8ef0-79fd-8a7d-eb8f8eb30ccb" xlink:to="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-78fd-95c3-d4b748de7645" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-700e-9145-e5ef62f0076f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashFlowHedgingMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_019f04d0-8ef0-78fd-95c3-d4b748de7645" xlink:to="loc_us-gaap_CashFlowHedgingMember_019f04d0-8ef0-700e-9145-e5ef62f0076f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-70c0-a823-ccf3b5c1450e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:to="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-70c0-a823-ccf3b5c1450e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-7d69-b436-b0486f8c82e6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_019f04d0-8ef0-70c0-a823-ccf3b5c1450e" xlink:to="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-7d69-b436-b0486f8c82e6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_AccumulatedGainLossNetCashFlowHedgeParentExclusiveOfImpairmentMember_019f04d0-8ef0-7879-a849-ba7836036626" xlink:href="cwk-20260630.xsd#cwk_AccumulatedGainLossNetCashFlowHedgeParentExclusiveOfImpairmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_019f04d0-8ef0-7d69-b436-b0486f8c82e6" xlink:to="loc_cwk_AccumulatedGainLossNetCashFlowHedgeParentExclusiveOfImpairmentMember_019f04d0-8ef0-7879-a849-ba7836036626" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_019f04d0-8ef0-7367-96fa-15562d5d9a1f" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7705-acf7-037fc8e3b81b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7d99-9e1c-6fbfdf89aa0e" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7705-acf7-037fc8e3b81b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateContractMember_019f04d0-8ef0-7f1a-95a4-8b032342a803" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateContractMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7705-acf7-037fc8e3b81b" xlink:to="loc_us-gaap_InterestRateContractMember_019f04d0-8ef0-7f1a-95a4-8b032342a803" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AOCIAttributableToParentNetOfTaxRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019f04d0-8ef0-7f72-9eb4-4eb72a37c877" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:to="loc_us-gaap_StockholdersEquity_019f04d0-8ef0-7f72-9eb4-4eb72a37c877" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019f04d0-8ef0-7826-bcd0-65bc1a63e9a5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019f04d0-8ef0-7826-bcd0-65bc1a63e9a5" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax_019f04d0-8ef0-7a2d-8bc4-9b6edd9c82a5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_019f04d0-8ef0-7f9f-bf05-3b6fb6ebe520" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax_019f04d0-8ef0-7a2d-8bc4-9b6edd9c82a5" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019f04d0-8ef0-7284-af7d-1fab33bd4fe7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_019f04d0-8ef0-768c-8db1-48f55d2c60ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_019f04d0-8ef0-768c-8db1-48f55d2c60ff" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_019f04d0-8ef0-79a1-9f65-d583d201363e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationFromAociCurrentPeriodTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_019f04d0-8ef0-73e7-a459-272aed50841d" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_019f04d0-8ef0-79a1-9f65-d583d201363e" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/LongTermDebtandOtherBorrowingsScheduleofLongTermDebtDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#LongTermDebtandOtherBorrowingsScheduleofLongTermDebtDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/LongTermDebtandOtherBorrowingsScheduleofLongTermDebtDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7c28-ae56-284031f3a4fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7c28-ae56-284031f3a4fc" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_019f04d0-8ef0-7303-965d-22a4e6409c56" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7c28-ae56-284031f3a4fc" xlink:to="loc_us-gaap_DebtInstrumentAxis_019f04d0-8ef0-7303-965d-22a4e6409c56" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-7303-965d-22a4e6409c56_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_019f04d0-8ef0-7303-965d-22a4e6409c56" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-7303-965d-22a4e6409c56_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-79e5-ae64-1c9c8b8d0cf5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_019f04d0-8ef0-7303-965d-22a4e6409c56" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-79e5-ae64-1c9c8b8d0cf5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TermLoanMaturingJanuary312030TrancheMember_019f04d0-8ef0-78b3-bfdb-76ce95470b0f" xlink:href="cwk-20260630.xsd#cwk_TermLoanMaturingJanuary312030TrancheMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-79e5-ae64-1c9c8b8d0cf5" xlink:to="loc_cwk_TermLoanMaturingJanuary312030TrancheMember_019f04d0-8ef0-78b3-bfdb-76ce95470b0f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TermLoanMaturingJanuary2030Tranche2Member_019f87b4-daff-771d-a343-5cad00e05374" xlink:href="cwk-20260630.xsd#cwk_TermLoanMaturingJanuary2030Tranche2Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-79e5-ae64-1c9c8b8d0cf5" xlink:to="loc_cwk_TermLoanMaturingJanuary2030Tranche2Member_019f87b4-daff-771d-a343-5cad00e05374" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TermLoanMaturingJune2033TrancheMember_019f04d0-8ef0-7327-9560-86f7d591d445" xlink:href="cwk-20260630.xsd#cwk_TermLoanMaturingJune2033TrancheMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-79e5-ae64-1c9c8b8d0cf5" xlink:to="loc_cwk_TermLoanMaturingJune2033TrancheMember_019f04d0-8ef0-7327-9560-86f7d591d445" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_SeniorSecuredNoteDueMay2028Member_019f04d0-8ef0-7952-bed4-9f63018b8c2a" xlink:href="cwk-20260630.xsd#cwk_SeniorSecuredNoteDueMay2028Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-79e5-ae64-1c9c8b8d0cf5" xlink:to="loc_cwk_SeniorSecuredNoteDueMay2028Member_019f04d0-8ef0-7952-bed4-9f63018b8c2a" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_SeniorSecuredNoteDueSeptember2031Member_019f04d0-8ef0-737a-9b53-bd846f73a78e" xlink:href="cwk-20260630.xsd#cwk_SeniorSecuredNoteDueSeptember2031Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f04d0-8ef0-79e5-ae64-1c9c8b8d0cf5" xlink:to="loc_cwk_SeniorSecuredNoteDueSeptember2031Member_019f04d0-8ef0-737a-9b53-bd846f73a78e" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_019f04d0-8ef0-71ed-ae42-69bb4dd1fc61" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7c28-ae56-284031f3a4fc" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_019f04d0-8ef0-71ed-ae42-69bb4dd1fc61" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_019f04d0-8ef0-71ed-ae42-69bb4dd1fc61_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_019f04d0-8ef0-71ed-ae42-69bb4dd1fc61" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_019f04d0-8ef0-71ed-ae42-69bb4dd1fc61_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_019f04d0-8ef0-73da-b9a5-ed937456337f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_019f04d0-8ef0-71ed-ae42-69bb4dd1fc61" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_019f04d0-8ef0-73da-b9a5-ed937456337f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredDebtMember_019f04d0-8ef0-7a16-8c0b-729b5de552f4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SecuredDebtMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_019f04d0-8ef0-73da-b9a5-ed937456337f" xlink:to="loc_us-gaap_SecuredDebtMember_019f04d0-8ef0-7a16-8c0b-729b5de552f4" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_SeniorSecuredNoteMember_019f04d0-8ef0-74cd-a8ef-e14873f99671" xlink:href="cwk-20260630.xsd#cwk_SeniorSecuredNoteMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_019f04d0-8ef0-73da-b9a5-ed937456337f" xlink:to="loc_cwk_SeniorSecuredNoteMember_019f04d0-8ef0-74cd-a8ef-e14873f99671" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_019f04d0-8ef0-7831-8ee7-1a0873c9efbc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_LongTermDebt_019f04d0-8ef0-7831-8ee7-1a0873c9efbc" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiability_019f04d0-8ef0-789d-aedc-2f7ca7c42bd5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FinanceLeaseLiability"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_FinanceLeaseLiability_019f04d0-8ef0-789d-aedc-2f7ca7c42bd5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_019f04d0-8ef0-74d0-8574-cf771d1fd86c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligations"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_019f04d0-8ef0-74d0-8574-cf771d1fd86c" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_019f04d0-8ef0-747f-b64a-b4247af17c9e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_LongTermDebtCurrent_019f04d0-8ef0-747f-b64a-b4247af17c9e" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_019f04d0-8ef0-7caa-88b2-fef6766313b0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_019f04d0-8ef0-7caa-88b2-fef6766313b0" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_019f04d0-8ef0-7ee8-bc4c-4a262e9192bf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_019f04d0-8ef0-7ee8-bc4c-4a262e9192bf" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_019f04d0-8ef0-7090-b553-20d7ce8a65f4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f04d0-8ef0-77bd-80fb-9dd120ad4ee9" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_019f04d0-8ef0-7090-b553-20d7ce8a65f4" xlink:type="arc" order="6"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/LongTermDebtandOtherBorrowingsNarrativeDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#LongTermDebtandOtherBorrowingsNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/LongTermDebtandOtherBorrowingsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7dc5-816a-d5eb0823239c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7dc5-816a-d5eb0823239c" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_019f91be-1ea5-7f5d-a4e2-c0094c7e4836" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7dc5-816a-d5eb0823239c" xlink:to="loc_us-gaap_DebtInstrumentAxis_019f91be-1ea5-7f5d-a4e2-c0094c7e4836" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7f5d-a4e2-c0094c7e4836_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_019f91be-1ea5-7f5d-a4e2-c0094c7e4836" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7f5d-a4e2-c0094c7e4836_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7dbb-86b1-72517d6c142d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_019f91be-1ea5-7f5d-a4e2-c0094c7e4836" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7dbb-86b1-72517d6c142d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_A2018CreditAgreementMember_019f91be-1ea5-7336-8d11-69feb6922415" xlink:href="cwk-20260630.xsd#cwk_A2018CreditAgreementMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7dbb-86b1-72517d6c142d" xlink:to="loc_cwk_A2018CreditAgreementMember_019f91be-1ea5-7336-8d11-69feb6922415" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TermLoansMember_019f91be-1ea5-7ccd-a7e2-bd70288c3476" xlink:href="cwk-20260630.xsd#cwk_TermLoansMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7dbb-86b1-72517d6c142d" xlink:to="loc_cwk_TermLoansMember_019f91be-1ea5-7ccd-a7e2-bd70288c3476" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TermLoanMaturingAugust2025Member_019f91be-1ea5-70aa-9afc-dd4dab8c4290" xlink:href="cwk-20260630.xsd#cwk_TermLoanMaturingAugust2025Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_cwk_TermLoansMember_019f91be-1ea5-7ccd-a7e2-bd70288c3476" xlink:to="loc_cwk_TermLoanMaturingAugust2025Member_019f91be-1ea5-70aa-9afc-dd4dab8c4290" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TermLoanMaturingJune2033TrancheMember_019f91be-1ea5-7cd3-9902-0744519ad886" xlink:href="cwk-20260630.xsd#cwk_TermLoanMaturingJune2033TrancheMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_cwk_TermLoansMember_019f91be-1ea5-7ccd-a7e2-bd70288c3476" xlink:to="loc_cwk_TermLoanMaturingJune2033TrancheMember_019f91be-1ea5-7cd3-9902-0744519ad886" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TermLoanMaturingJanuary312030TrancheMember_019f91be-1ea5-7d48-ab99-a08ae04dbcf8" xlink:href="cwk-20260630.xsd#cwk_TermLoanMaturingJanuary312030TrancheMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_cwk_TermLoansMember_019f91be-1ea5-7ccd-a7e2-bd70288c3476" xlink:to="loc_cwk_TermLoanMaturingJanuary312030TrancheMember_019f91be-1ea5-7d48-ab99-a08ae04dbcf8" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_SeniorSecuredNoteDueMay2028Member_019f91be-58f9-7b23-b364-700863f29723" xlink:href="cwk-20260630.xsd#cwk_SeniorSecuredNoteDueMay2028Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7dbb-86b1-72517d6c142d" xlink:to="loc_cwk_SeniorSecuredNoteDueMay2028Member_019f91be-58f9-7b23-b364-700863f29723" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_SeniorSecuredNoteDueSept2031Member_019f91be-58f9-7981-843f-cc3085e6107a" xlink:href="cwk-20260630.xsd#cwk_SeniorSecuredNoteDueSept2031Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_019f91be-1ea5-7dbb-86b1-72517d6c142d" xlink:to="loc_cwk_SeniorSecuredNoteDueSept2031Member_019f91be-58f9-7981-843f-cc3085e6107a" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_019f91be-1ea5-7808-8d58-683529a05e40" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7dc5-816a-d5eb0823239c" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_019f91be-1ea5-7808-8d58-683529a05e40" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_019f91be-1ea5-7808-8d58-683529a05e40_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_019f91be-1ea5-7808-8d58-683529a05e40" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_019f91be-1ea5-7808-8d58-683529a05e40_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_019f91be-1ea5-7d79-9f4c-c2e921bcd128" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_019f91be-1ea5-7808-8d58-683529a05e40" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_019f91be-1ea5-7d79-9f4c-c2e921bcd128" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredDebtMember_019f91be-1ea5-7345-a893-e300ba71978f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SecuredDebtMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_019f91be-1ea5-7d79-9f4c-c2e921bcd128" xlink:to="loc_us-gaap_SecuredDebtMember_019f91be-1ea5-7345-a893-e300ba71978f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditMember_019f91be-1ea5-7ea4-83a9-1caf5d83130c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_019f91be-1ea5-7d79-9f4c-c2e921bcd128" xlink:to="loc_us-gaap_LineOfCreditMember_019f91be-1ea5-7ea4-83a9-1caf5d83130c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_SeniorSecuredNoteMember_019f91be-58f9-73fa-9a72-ea4ddffad6ad" xlink:href="cwk-20260630.xsd#cwk_SeniorSecuredNoteMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_019f91be-1ea5-7d79-9f4c-c2e921bcd128" xlink:to="loc_cwk_SeniorSecuredNoteMember_019f91be-58f9-73fa-9a72-ea4ddffad6ad" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis_019f91be-1ea5-7ddc-a852-74e8f881968f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_VariableRateAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7dc5-816a-d5eb0823239c" xlink:to="loc_us-gaap_VariableRateAxis_019f91be-1ea5-7ddc-a852-74e8f881968f" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_019f91be-1ea5-7ddc-a852-74e8f881968f_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_VariableRateDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_VariableRateAxis_019f91be-1ea5-7ddc-a852-74e8f881968f" xlink:to="loc_us-gaap_VariableRateDomain_019f91be-1ea5-7ddc-a852-74e8f881968f_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_019f91be-1ea5-75f0-af37-bc4de2d97c70" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_VariableRateDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_VariableRateAxis_019f91be-1ea5-7ddc-a852-74e8f881968f" xlink:to="loc_us-gaap_VariableRateDomain_019f91be-1ea5-75f0-af37-bc4de2d97c70" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredOvernightFinancingRateSofrMember_019f91be-1ea5-7b06-ba07-ddd1f2fb2a22" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SecuredOvernightFinancingRateSofrMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_VariableRateDomain_019f91be-1ea5-75f0-af37-bc4de2d97c70" xlink:to="loc_us-gaap_SecuredOvernightFinancingRateSofrMember_019f91be-1ea5-7b06-ba07-ddd1f2fb2a22" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BaseRateMember_019f91be-1ea5-77bf-bf02-676318df9669" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BaseRateMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_VariableRateDomain_019f91be-1ea5-75f0-af37-bc4de2d97c70" xlink:to="loc_us-gaap_BaseRateMember_019f91be-1ea5-77bf-bf02-676318df9669" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_019f91be-1ea5-7e90-8a81-199927076dc4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7dc5-816a-d5eb0823239c" xlink:to="loc_us-gaap_CreditFacilityAxis_019f91be-1ea5-7e90-8a81-199927076dc4" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_019f91be-1ea5-7e90-8a81-199927076dc4_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CreditFacilityAxis_019f91be-1ea5-7e90-8a81-199927076dc4" xlink:to="loc_us-gaap_CreditFacilityDomain_019f91be-1ea5-7e90-8a81-199927076dc4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_019f91be-1ea5-70d2-91e5-d4e790e97288" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CreditFacilityAxis_019f91be-1ea5-7e90-8a81-199927076dc4" xlink:to="loc_us-gaap_CreditFacilityDomain_019f91be-1ea5-70d2-91e5-d4e790e97288" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_019f91be-1ea5-7b69-80f3-dbd6e908396c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevolvingCreditFacilityMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_019f91be-1ea5-70d2-91e5-d4e790e97288" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_019f91be-1ea5-7b69-80f3-dbd6e908396c" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_019f91be-1ea5-7ec2-b652-4e5611238f9f" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_019f04d0-8ef0-7dc5-816a-d5eb0823239c" xlink:to="loc_srt_RangeAxis_019f91be-1ea5-7ec2-b652-4e5611238f9f" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_019f91be-1ea5-7ec2-b652-4e5611238f9f_default" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_019f91be-1ea5-7ec2-b652-4e5611238f9f" xlink:to="loc_srt_RangeMember_019f91be-1ea5-7ec2-b652-4e5611238f9f_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_019f91be-1ea5-7bba-a368-b1a34f42438d" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_019f91be-1ea5-7ec2-b652-4e5611238f9f" xlink:to="loc_srt_RangeMember_019f91be-1ea5-7bba-a368-b1a34f42438d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_019f91be-1ea5-74ea-83d8-6c107dec6729" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_019f91be-1ea5-7bba-a368-b1a34f42438d" xlink:to="loc_srt_MinimumMember_019f91be-1ea5-74ea-83d8-6c107dec6729" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_019f91be-1ea5-732d-8cf8-db226425c4ed" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_019f91be-1ea5-7bba-a368-b1a34f42438d" xlink:to="loc_srt_MaximumMember_019f91be-1ea5-732d-8cf8-db226425c4ed" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_019f91be-1ea5-7ec3-bc8c-c6598a0f8b93" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_019f91be-1ea5-7ec3-bc8c-c6598a0f8b93" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_019f91be-1ea5-73f4-9bf9-2b519de967df" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_019f91be-1ea5-73f4-9bf9-2b519de967df" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentIncreaseDecreaseForPeriodNet_019f91be-1ea5-7f50-b8c9-03c26b8e6858" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentIncreaseDecreaseForPeriodNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DebtInstrumentIncreaseDecreaseForPeriodNet_019f91be-1ea5-7f50-b8c9-03c26b8e6858" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_019f91be-1ea5-7a1f-8706-a1ab58398d70" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_019f91be-1ea5-7a1f-8706-a1ab58398d70" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedAmortizationDeferredFinanceCosts_019f91be-1ea5-739f-917d-839b91b691d0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedAmortizationDeferredFinanceCosts"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_AccumulatedAmortizationDeferredFinanceCosts_019f91be-1ea5-739f-917d-839b91b691d0" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_019f91be-1ea5-79df-a75f-ccc49e9fde03" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestExpenseDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_InterestExpenseDebt_019f91be-1ea5-79df-a75f-ccc49e9fde03" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_DebtInstrumentQuarterlyPrincipalPaymentPercentage_019f91be-1ea5-7833-9f42-2b018dfe815c" xlink:href="cwk-20260630.xsd#cwk_DebtInstrumentQuarterlyPrincipalPaymentPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_cwk_DebtInstrumentQuarterlyPrincipalPaymentPercentage_019f91be-1ea5-7833-9f42-2b018dfe815c" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_019f91be-1ea5-7fce-8fa2-e70f7d50b00a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_019f91be-1ea5-7fce-8fa2-e70f7d50b00a" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_DebtInstrumentBasisSpreadOnVariableRateMinimumFloor_019f91be-1ea5-78d6-8c13-03d07d7cb784" xlink:href="cwk-20260630.xsd#cwk_DebtInstrumentBasisSpreadOnVariableRateMinimumFloor"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_cwk_DebtInstrumentBasisSpreadOnVariableRateMinimumFloor_019f91be-1ea5-78d6-8c13-03d07d7cb784" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_019f91be-1ea5-77d5-964f-46aa6ce4e9f8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_019f91be-1ea5-77d5-964f-46aa6ce4e9f8" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_019f91be-1ea5-7fd8-b01d-d03af280a18f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_019f91be-1ea5-7fd8-b01d-d03af280a18f" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_019f91be-58f9-7949-867a-07c65ead2af4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_019f91be-58f9-7949-867a-07c65ead2af4" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSeniorLongTermDebt_019f91be-58fa-786d-b435-b6a09e2f39fb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfSeniorLongTermDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSeniorLongTermDebt_019f91be-58fa-786d-b435-b6a09e2f39fb" xlink:type="arc" order="12"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsGross_019f91be-58fa-7d44-acdd-e5f04baeacbe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredFinanceCostsGross"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DeferredFinanceCostsGross_019f91be-58fa-7d44-acdd-e5f04baeacbe" xlink:type="arc" order="13"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019f91be-58fa-7a2b-a6b3-1d1b949c65d2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019f91be-58fa-7a2b-a6b3-1d1b949c65d2" xlink:type="arc" order="14"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_019f91be-58fa-798e-9c76-dd074b559bd5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_019f91be-58fa-798e-9c76-dd074b559bd5" xlink:type="arc" order="15"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_DebtInstrumentCovenantLeverageRatio_019f91be-58fa-73ed-a829-60283db1760f" xlink:href="cwk-20260630.xsd#cwk_DebtInstrumentCovenantLeverageRatio"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_019f91be-1ea5-7c0e-bc00-d4138e07d153" xlink:to="loc_cwk_DebtInstrumentCovenantLeverageRatio_019f91be-58fa-73ed-a829-60283db1760f" xlink:type="arc" order="16"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/EmployeeBenefitsDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#EmployeeBenefitsDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/EmployeeBenefitsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_019f04d0-8ef0-7ab9-b852-fb60083ec2b7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanDisclosureLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_019f04d0-8ef0-72fc-8798-0fc04e684187" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_019f04d0-8ef0-7ab9-b852-fb60083ec2b7" xlink:to="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_019f04d0-8ef0-72fc-8798-0fc04e684187" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationAxis_019f04d0-8ef0-7270-9369-1ce76b822f9e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetirementPlanSponsorLocationAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfDefinedBenefitPlansDisclosuresTable_019f04d0-8ef0-72fc-8798-0fc04e684187" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationAxis_019f04d0-8ef0-7270-9369-1ce76b822f9e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_019f04d0-8ef0-7270-9369-1ce76b822f9e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_019f04d0-8ef0-7270-9369-1ce76b822f9e" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_019f04d0-8ef0-7270-9369-1ce76b822f9e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetirementPlanSponsorLocationDomain_019f04d0-8ef0-720e-911f-8cef3d04c8ef" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetirementPlanSponsorLocationDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationAxis_019f04d0-8ef0-7270-9369-1ce76b822f9e" xlink:to="loc_us-gaap_RetirementPlanSponsorLocationDomain_019f04d0-8ef0-720e-911f-8cef3d04c8ef" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignPlanMember_019f04d0-8ef0-79a1-8b32-f3eca82d9e00" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignPlanMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RetirementPlanSponsorLocationDomain_019f04d0-8ef0-720e-911f-8cef3d04c8ef" xlink:to="loc_us-gaap_ForeignPlanMember_019f04d0-8ef0-79a1-8b32-f3eca82d9e00" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_GB_019f04d0-8ef0-716c-8d86-4dd99ddac0c4" xlink:href="https://xbrl.sec.gov/country/2026/country-2026.xsd#country_GB"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ForeignPlanMember_019f04d0-8ef0-79a1-8b32-f3eca82d9e00" xlink:to="loc_country_GB_019f04d0-8ef0-716c-8d86-4dd99ddac0c4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_NumberOfDefinedBenefitPlans_019f04d0-8ef0-729f-819e-69e13bbbbb99" xlink:href="cwk-20260630.xsd#cwk_NumberOfDefinedBenefitPlans"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_019f04d0-8ef0-7ab9-b852-fb60083ec2b7" xlink:to="loc_cwk_NumberOfDefinedBenefitPlans_019f04d0-8ef0-729f-819e-69e13bbbbb99" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_019f04d0-8ef0-7146-9a8a-fcd27b552638" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanFairValueOfPlanAssets"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_019f04d0-8ef0-7ab9-b852-fb60083ec2b7" xlink:to="loc_us-gaap_DefinedBenefitPlanFairValueOfPlanAssets_019f04d0-8ef0-7146-9a8a-fcd27b552638" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanBenefitObligation_019f04d0-8ef0-7e86-b098-334a612fe81e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanBenefitObligation"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_019f04d0-8ef0-7ab9-b852-fb60083ec2b7" xlink:to="loc_us-gaap_DefinedBenefitPlanBenefitObligation_019f04d0-8ef0-7e86-b098-334a612fe81e" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlements1_019f04d0-8ef0-77f1-8f71-a7875302b2ac" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlements1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DefinedBenefitPlanDisclosureLineItems_019f04d0-8ef0-7ab9-b852-fb60083ec2b7" xlink:to="loc_us-gaap_DefinedBenefitPlanRecognizedNetGainLossDueToSettlements1_019f04d0-8ef0-77f1-8f71-a7875302b2ac" xlink:type="arc" order="3"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/CommitmentsandContingenciesDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#CommitmentsandContingenciesDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/CommitmentsandContingenciesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingenciesLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesTable_019f04d0-8ef0-72cf-82f3-5ea7225b9bad" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingenciesTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_LossContingenciesTable_019f04d0-8ef0-72cf-82f3-5ea7225b9bad" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_019f04d0-8ef0-78c2-b537-474602f97948" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingenciesByNatureOfContingencyAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LossContingenciesTable_019f04d0-8ef0-72cf-82f3-5ea7225b9bad" xlink:to="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_019f04d0-8ef0-78c2-b537-474602f97948" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_019f04d0-8ef0-78c2-b537-474602f97948_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingencyNatureDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_019f04d0-8ef0-78c2-b537-474602f97948" xlink:to="loc_us-gaap_LossContingencyNatureDomain_019f04d0-8ef0-78c2-b537-474602f97948_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNatureDomain_019f04d0-8ef0-7006-8cf6-8a6414830502" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingencyNatureDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LossContingenciesByNatureOfContingencyAxis_019f04d0-8ef0-78c2-b537-474602f97948" xlink:to="loc_us-gaap_LossContingencyNatureDomain_019f04d0-8ef0-7006-8cf6-8a6414830502" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_ErrorsAndOmissionsClaimsMember_019f04d0-8ef0-7d74-8083-5f9d680b98d7" xlink:href="cwk-20260630.xsd#cwk_ErrorsAndOmissionsClaimsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyNatureDomain_019f04d0-8ef0-7006-8cf6-8a6414830502" xlink:to="loc_cwk_ErrorsAndOmissionsClaimsMember_019f04d0-8ef0-7d74-8083-5f9d680b98d7" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_WorkersCompensationMember_019f04d0-8ef0-7b5d-90b6-11f9683ccc8d" xlink:href="cwk-20260630.xsd#cwk_WorkersCompensationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyNatureDomain_019f04d0-8ef0-7006-8cf6-8a6414830502" xlink:to="loc_cwk_WorkersCompensationMember_019f04d0-8ef0-7b5d-90b6-11f9683ccc8d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7567-91cf-f9feb8fb4798" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LossContingenciesTable_019f04d0-8ef0-72cf-82f3-5ea7225b9bad" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7567-91cf-f9feb8fb4798" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7567-91cf-f9feb8fb4798_default" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_EquityMethodInvesteeNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7567-91cf-f9feb8fb4798" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7567-91cf-f9feb8fb4798_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7136-9d5c-ff3e8639c456" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_EquityMethodInvesteeNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_019f04d0-8ef0-7567-91cf-f9feb8fb4798" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7136-9d5c-ff3e8639c456" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_GreystoneJVMember_019f04d0-8ef0-7918-8b73-b84abc546d82" xlink:href="cwk-20260630.xsd#cwk_GreystoneJVMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_019f04d0-8ef0-7136-9d5c-ff3e8639c456" xlink:to="loc_cwk_GreystoneJVMember_019f04d0-8ef0-7918-8b73-b84abc546d82" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_019f04d0-8ef0-7e84-acae-a2712d516cd9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingencyAccrualCarryingValueCurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_019f04d0-8ef0-7e84-acae-a2712d516cd9" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_019f04d0-8ef0-74dd-b553-262de0024156" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingencyAccrualCarryingValueNoncurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_019f04d0-8ef0-74dd-b553-262de0024156" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_019f04d0-8ef0-7ac0-8427-b39adb73c6ec" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingencyAccrualAtCarryingValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_019f04d0-8ef0-7ac0-8427-b39adb73c6ec" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedPayrollTaxesCurrentAndNoncurrent_019f04d0-8ef0-7c79-80bf-8fe676a2c14c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedPayrollTaxesCurrentAndNoncurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_AccruedPayrollTaxesCurrentAndNoncurrent_019f04d0-8ef0-7c79-80bf-8fe676a2c14c" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExaminationEstimateOfPossibleLoss_019f04d0-8ef0-753c-bee3-3204e39e8a5c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeTaxExaminationEstimateOfPossibleLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_IncomeTaxExaminationEstimateOfPossibleLoss_019f04d0-8ef0-753c-bee3-3204e39e8a5c" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_GuarantorObligationsCloseEndedTerm_019f04d0-8ef0-7242-9d8a-8cec2537cf82" xlink:href="cwk-20260630.xsd#cwk_GuarantorObligationsCloseEndedTerm"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_cwk_GuarantorObligationsCloseEndedTerm_019f04d0-8ef0-7242-9d8a-8cec2537cf82" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteeObligationsMaximumExposure_019f04d0-8ef0-7ed1-bdc6-74fa9da1ac63" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GuaranteeObligationsMaximumExposure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_GuaranteeObligationsMaximumExposure_019f04d0-8ef0-7ed1-bdc6-74fa9da1ac63" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_NumberOfLoanCommitmentLettersIssued_019f04d0-8ef0-7b45-9a4b-f06ba021fee7" xlink:href="cwk-20260630.xsd#cwk_NumberOfLoanCommitmentLettersIssued"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_cwk_NumberOfLoanCommitmentLettersIssued_019f04d0-8ef0-7b45-9a4b-f06ba021fee7" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_NumberOfFirstMortgageMultifamilyPropertyLoans_019f04d0-8ef0-7318-984e-5ee9e74a0aed" xlink:href="cwk-20260630.xsd#cwk_NumberOfFirstMortgageMultifamilyPropertyLoans"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_cwk_NumberOfFirstMortgageMultifamilyPropertyLoans_019f04d0-8ef0-7318-984e-5ee9e74a0aed" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_NumberOfLoansDelivered_019f04d0-8ef0-77db-8bd1-76d4e96ebf0b" xlink:href="cwk-20260630.xsd#cwk_NumberOfLoansDelivered"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_cwk_NumberOfLoansDelivered_019f04d0-8ef0-77db-8bd1-76d4e96ebf0b" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_019f04d0-8ef0-7a32-a094-8cfe32582a30" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProvisionForLoanLeaseAndOtherLosses"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_ProvisionForLoanLeaseAndOtherLosses_019f04d0-8ef0-7a32-a094-8cfe32582a30" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_019f04d0-8ef0-7181-92eb-db50bd98de99" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_019f04d0-8ef0-7181-92eb-db50bd98de99" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationSettlementExpense_019f04d0-8ef0-7958-8e79-0fa57ccf4d96" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LitigationSettlementExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_019f04d0-8ef0-71ec-929e-cbff27de344b" xlink:to="loc_us-gaap_LitigationSettlementExpense_019f04d0-8ef0-7958-8e79-0fa57ccf4d96" xlink:type="arc" order="12"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/RelatedPartyTransactionsandEmployeeReceivablesDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#RelatedPartyTransactionsandEmployeeReceivablesDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/RelatedPartyTransactionsandEmployeeReceivablesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionLineItems_019f04d0-8ef0-757d-a382-9d9fd427af94" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RelatedPartyTransactionLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_019f04d0-8ef0-7cf0-a9b8-6100b2fbb7d4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_019f04d0-8ef0-757d-a382-9d9fd427af94" xlink:to="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_019f04d0-8ef0-7cf0-a9b8-6100b2fbb7d4" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_019f04d0-8ef0-7abe-86cd-fc1dc4b98d08" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_019f04d0-8ef0-7cf0-a9b8-6100b2fbb7d4" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_019f04d0-8ef0-7abe-86cd-fc1dc4b98d08" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_019f04d0-8ef0-7abe-86cd-fc1dc4b98d08_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RelatedPartyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_019f04d0-8ef0-7abe-86cd-fc1dc4b98d08" xlink:to="loc_us-gaap_RelatedPartyDomain_019f04d0-8ef0-7abe-86cd-fc1dc4b98d08_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_019f04d0-8ef0-7a8f-8a5d-aebc4d6029b6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RelatedPartyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_019f04d0-8ef0-7abe-86cd-fc1dc4b98d08" xlink:to="loc_us-gaap_RelatedPartyDomain_019f04d0-8ef0-7a8f-8a5d-aebc4d6029b6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyMember_019f04d0-8ef0-78ec-9021-ac92de41d1ce" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RelatedPartyMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyDomain_019f04d0-8ef0-7a8f-8a5d-aebc4d6029b6" xlink:to="loc_us-gaap_RelatedPartyMember_019f04d0-8ef0-78ec-9021-ac92de41d1ce" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServiceExcludingDepreciationDepletionAndAmortization_019f04d0-8ef0-7bcf-b998-05c867a376c7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServiceExcludingDepreciationDepletionAndAmortization"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_019f04d0-8ef0-757d-a382-9d9fd427af94" xlink:to="loc_us-gaap_CostOfGoodsAndServiceExcludingDepreciationDepletionAndAmortization_019f04d0-8ef0-7bcf-b998-05c867a376c7" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivablesNetCurrent_019f04d0-8ef0-71a5-b98f-0ce4bf7b5cd0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherReceivablesNetCurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_019f04d0-8ef0-757d-a382-9d9fd427af94" xlink:to="loc_us-gaap_OtherReceivablesNetCurrent_019f04d0-8ef0-71a5-b98f-0ce4bf7b5cd0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivableAfterAllowanceForCreditLossNoncurrent_019f04d0-8ef0-7ccf-8031-83e4ac501860" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherReceivableAfterAllowanceForCreditLossNoncurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_019f04d0-8ef0-757d-a382-9d9fd427af94" xlink:to="loc_us-gaap_OtherReceivableAfterAllowanceForCreditLossNoncurrent_019f04d0-8ef0-7ccf-8031-83e4ac501860" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#FairValueMeasurementsNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7225-bcbd-c6eca4dc6c67" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7225-bcbd-c6eca4dc6c67" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_019f04d0-8ef0-75ab-9e0d-7928d7ade4ed" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7225-bcbd-c6eca4dc6c67" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_019f04d0-8ef0-75ab-9e0d-7928d7ade4ed" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_019f04d0-8ef0-75ab-9e0d-7928d7ade4ed_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_019f04d0-8ef0-75ab-9e0d-7928d7ade4ed" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_019f04d0-8ef0-75ab-9e0d-7928d7ade4ed_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_019f04d0-8ef0-7a26-88cd-820beba4a6b0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_019f04d0-8ef0-75ab-9e0d-7928d7ade4ed" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_019f04d0-8ef0-7a26-88cd-820beba4a6b0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_SeveralEstateServiceCompaniesMember_019f04d0-8ef0-74aa-8848-1db972759f27" xlink:href="cwk-20260630.xsd#cwk_SeveralEstateServiceCompaniesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_019f04d0-8ef0-7a26-88cd-820beba4a6b0" xlink:to="loc_cwk_SeveralEstateServiceCompaniesMember_019f04d0-8ef0-74aa-8848-1db972759f27" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis_019f04d0-8ef0-7770-bd0c-a45a5ebbac8a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7225-bcbd-c6eca4dc6c67" xlink:to="loc_us-gaap_InvestmentTypeAxis_019f04d0-8ef0-7770-bd0c-a45a5ebbac8a" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_019f04d0-8ef0-7770-bd0c-a45a5ebbac8a_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_InvestmentTypeAxis_019f04d0-8ef0-7770-bd0c-a45a5ebbac8a" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_019f04d0-8ef0-7770-bd0c-a45a5ebbac8a_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember_019f04d0-8ef0-7bc7-a28f-75ea1eb1585c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_InvestmentTypeAxis_019f04d0-8ef0-7770-bd0c-a45a5ebbac8a" xlink:to="loc_us-gaap_InvestmentTypeCategorizationMember_019f04d0-8ef0-7bc7-a28f-75ea1eb1585c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_EarlyStateProptechCompaniesMember_019f04d0-8ef0-702f-bd94-bd6aedf8ca99" xlink:href="cwk-20260630.xsd#cwk_EarlyStateProptechCompaniesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_019f04d0-8ef0-7bc7-a28f-75ea1eb1585c" xlink:to="loc_cwk_EarlyStateProptechCompaniesMember_019f04d0-8ef0-702f-bd94-bd6aedf8ca99" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_TradedRealEstateCompaniesMember_019f04d0-8ef0-7b13-ab1a-08e1e060efd4" xlink:href="cwk-20260630.xsd#cwk_TradedRealEstateCompaniesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_019f04d0-8ef0-7bc7-a28f-75ea1eb1585c" xlink:to="loc_cwk_TradedRealEstateCompaniesMember_019f04d0-8ef0-7b13-ab1a-08e1e060efd4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_RealEstateVentureCapitalFundsMember_019f04d0-8ef0-71e4-b46d-5f20680ceda7" xlink:href="cwk-20260630.xsd#cwk_RealEstateVentureCapitalFundsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember_019f04d0-8ef0-7bc7-a28f-75ea1eb1585c" xlink:to="loc_cwk_RealEstateVentureCapitalFundsMember_019f04d0-8ef0-71e4-b46d-5f20680ceda7" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtFairValue_019f04d0-8ef0-70c6-9e89-571607f8ba5d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_us-gaap_LongTermDebtFairValue_019f04d0-8ef0-70c6-9e89-571607f8ba5d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_019f04d0-8ef0-70d4-b40e-d2c4944a4ee3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_019f04d0-8ef0-70d4-b40e-d2c4944a4ee3" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_019f04d0-8ef0-73f7-befd-d67d9102bea0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_019f04d0-8ef0-73f7-befd-d67d9102bea0" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueLow_019f04d0-8ef0-73cc-9907-11e94d63150b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueLow"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueLow_019f04d0-8ef0-73cc-9907-11e94d63150b" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_BusinessCombinationContingentConsiderationArrangementsEarnOutPayment_019f04d0-8ef0-722a-9d77-6b68aca2b5ec" xlink:href="cwk-20260630.xsd#cwk_BusinessCombinationContingentConsiderationArrangementsEarnOutPayment"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_cwk_BusinessCombinationContingentConsiderationArrangementsEarnOutPayment_019f04d0-8ef0-722a-9d77-6b68aca2b5ec" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealEstateInvestments_019f04d0-8ef0-7117-94d2-ec9ae844e44a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RealEstateInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_us-gaap_RealEstateInvestments_019f04d0-8ef0-7117-94d2-ec9ae844e44a" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossOnInvestments_019f04d0-8ef0-7708-8233-b509cfc35bc8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_UnrealizedGainLossOnInvestments"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-771a-8f90-d15d30f48ae3" xlink:to="loc_us-gaap_UnrealizedGainLossOnInvestments_019f04d0-8ef0-7708-8233-b509cfc35bc8" xlink:type="arc" order="6"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/FairValueMeasurementsScheduleofRecurringFairValueMeasurementsDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#FairValueMeasurementsScheduleofRecurringFairValueMeasurementsDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/FairValueMeasurementsScheduleofRecurringFairValueMeasurementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-77cd-a789-b1e6285aa49e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7688-ba7b-f72a2ad903b9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-77cd-a789-b1e6285aa49e" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7688-ba7b-f72a2ad903b9" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7109-a809-fcfe9edf7e98" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeInstrumentRiskAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7688-ba7b-f72a2ad903b9" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7109-a809-fcfe9edf7e98" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7109-a809-fcfe9edf7e98_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7109-a809-fcfe9edf7e98" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7109-a809-fcfe9edf7e98_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7216-ab82-d2db1919f8e8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeContractTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_019f04d0-8ef0-7109-a809-fcfe9edf7e98" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7216-ab82-d2db1919f8e8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestRateSwapMember_019f04d0-8ef0-78a0-96e4-588827cd54dd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestRateSwapMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7216-ab82-d2db1919f8e8" xlink:to="loc_us-gaap_InterestRateSwapMember_019f04d0-8ef0-78a0-96e4-588827cd54dd" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignExchangeForwardMember_019f04d0-8ef0-7eec-af6b-072fc23df4ae" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ForeignExchangeForwardMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_019f04d0-8ef0-7216-ab82-d2db1919f8e8" xlink:to="loc_us-gaap_ForeignExchangeForwardMember_019f04d0-8ef0-7eec-af6b-072fc23df4ae" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_019f04d0-8ef0-7fb4-adda-7589839f75df" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_019f04d0-8ef0-7688-ba7b-f72a2ad903b9" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_019f04d0-8ef0-7fb4-adda-7589839f75df" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019f04d0-8ef0-7fb4-adda-7589839f75df_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_019f04d0-8ef0-7fb4-adda-7589839f75df" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019f04d0-8ef0-7fb4-adda-7589839f75df_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019f04d0-8ef0-7d32-9d4c-8c0fed0fbcf6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_019f04d0-8ef0-7fb4-adda-7589839f75df" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019f04d0-8ef0-7d32-9d4c-8c0fed0fbcf6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_019f04d0-8ef0-7457-a1e8-788f4cc01b16" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019f04d0-8ef0-7d32-9d4c-8c0fed0fbcf6" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_019f04d0-8ef0-7457-a1e8-788f4cc01b16" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_019f04d0-8ef0-767b-8051-930c3989635e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019f04d0-8ef0-7d32-9d4c-8c0fed0fbcf6" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_019f04d0-8ef0-767b-8051-930c3989635e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_019f04d0-8ef0-77ec-b684-cb70afac9dec" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019f04d0-8ef0-7d32-9d4c-8c0fed0fbcf6" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_019f04d0-8ef0-77ec-b684-cb70afac9dec" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_019f04d0-8ef0-7219-8005-aaac4ffe5e79" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsFairValueDisclosureAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-77cd-a789-b1e6285aa49e" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_019f04d0-8ef0-7219-8005-aaac4ffe5e79" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_019f04d0-8ef0-76d0-bfdb-a64ce83e79de" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_019f04d0-8ef0-7219-8005-aaac4ffe5e79" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_019f04d0-8ef0-76d0-bfdb-a64ce83e79de" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationPlanAssets_019f04d0-8ef0-729b-bdd4-73c4bf8d45bb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredCompensationPlanAssets"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_019f04d0-8ef0-7219-8005-aaac4ffe5e79" xlink:to="loc_us-gaap_DeferredCompensationPlanAssets_019f04d0-8ef0-729b-bdd4-73c4bf8d45bb" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeAssets_019f04d0-8ef0-7528-ab06-365db2845f22" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeAssets"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_019f04d0-8ef0-7219-8005-aaac4ffe5e79" xlink:to="loc_us-gaap_DerivativeAssets_019f04d0-8ef0-7528-ab06-365db2845f22" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNi_019f04d0-8ef0-7dbc-8a69-db00561c3c49" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquitySecuritiesFvNi"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_019f04d0-8ef0-7219-8005-aaac4ffe5e79" xlink:to="loc_us-gaap_EquitySecuritiesFvNi_019f04d0-8ef0-7dbc-8a69-db00561c3c49" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_019f04d0-8ef0-7535-938c-fdf48d301581" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_019f04d0-8ef0-7219-8005-aaac4ffe5e79" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_019f04d0-8ef0-7535-938c-fdf48d301581" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_019f04d0-8ef0-7d8d-9319-976024cbe8b0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_019f04d0-8ef0-77cd-a789-b1e6285aa49e" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_019f04d0-8ef0-7d8d-9319-976024cbe8b0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationLiabilityCurrentAndNoncurrent_019f04d0-8ef0-77cc-8499-a8bd154246d6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredCompensationLiabilityCurrentAndNoncurrent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_019f04d0-8ef0-7d8d-9319-976024cbe8b0" xlink:to="loc_us-gaap_DeferredCompensationLiabilityCurrentAndNoncurrent_019f04d0-8ef0-77cc-8499-a8bd154246d6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilities_019f04d0-8ef0-78d8-ac43-6638f213058d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DerivativeLiabilities"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_019f04d0-8ef0-7d8d-9319-976024cbe8b0" xlink:to="loc_us-gaap_DerivativeLiabilities_019f04d0-8ef0-78d8-ac43-6638f213058d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_019f04d0-8ef0-7d23-88ae-4fff8cc2c7d5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_019f04d0-8ef0-7d8d-9319-976024cbe8b0" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_019f04d0-8ef0-7d23-88ae-4fff8cc2c7d5" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_019f04d0-8ef0-74f3-843e-81c4f297bcec" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_019f04d0-8ef0-7d8d-9319-976024cbe8b0" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_019f04d0-8ef0-74f3-843e-81c4f297bcec" xlink:type="arc" order="4"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.cushmanwakefield.com/role/FairValueMeasurementsScheduleofFairValueLiabilitiesMeasuredonRecurringBasisUnobservableInputReconciliationDetails" xlink:type="simple" xlink:href="cwk-20260630.xsd#FairValueMeasurementsScheduleofFairValueLiabilitiesMeasuredonRecurringBasisUnobservableInputReconciliationDetails"/>
  <link:definitionLink xlink:role="http://www.cushmanwakefield.com/role/FairValueMeasurementsScheduleofFairValueLiabilitiesMeasuredonRecurringBasisUnobservableInputReconciliationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_019f04d0-8ef0-763e-80f1-a36da3abed06" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_019f04d0-8ef0-70f0-8eb4-73a99b655eaf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_019f04d0-8ef0-763e-80f1-a36da3abed06" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_019f04d0-8ef0-70f0-8eb4-73a99b655eaf" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByLiabilityClassAxis_019f04d0-8ef0-73cd-b3fd-10dabfcf824d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueByLiabilityClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTable_019f04d0-8ef0-70f0-8eb4-73a99b655eaf" xlink:to="loc_us-gaap_FairValueByLiabilityClassAxis_019f04d0-8ef0-73cd-b3fd-10dabfcf824d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_019f04d0-8ef0-73cd-b3fd-10dabfcf824d_default" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_019f04d0-8ef0-73cd-b3fd-10dabfcf824d" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_019f04d0-8ef0-73cd-b3fd-10dabfcf824d_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_019f04d0-8ef0-7bee-96d7-31a5acb19ecc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByLiabilityClassAxis_019f04d0-8ef0-73cd-b3fd-10dabfcf824d" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_019f04d0-8ef0-7bee-96d7-31a5acb19ecc" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_cwk_EarnOutLiabilitiesMember_019f04d0-8ef0-7baf-b993-ba83e9786f81" xlink:href="cwk-20260630.xsd#cwk_EarnOutLiabilitiesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationByLiabilityClassDomain_019f04d0-8ef0-7bee-96d7-31a5acb19ecc" xlink:to="loc_cwk_EarnOutLiabilitiesMember_019f04d0-8ef0-7baf-b993-ba83e9786f81" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_019f04d0-8ef0-70c6-8503-fb28340de9c6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationLineItems_019f04d0-8ef0-763e-80f1-a36da3abed06" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_019f04d0-8ef0-70c6-8503-fb28340de9c6" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_019f04d0-8ef0-781f-9d5f-4e6bcc48e29f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_019f04d0-8ef0-70c6-8503-fb28340de9c6" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_019f04d0-8ef0-781f-9d5f-4e6bcc48e29f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases_019f04d0-8ef0-7170-bd7a-8765b10ee584" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_019f04d0-8ef0-70c6-8503-fb28340de9c6" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases_019f04d0-8ef0-7170-bd7a-8765b10ee584" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_019f04d0-8ef0-7dfc-b126-4640f0d7b628" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_019f04d0-8ef0-70c6-8503-fb28340de9c6" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_019f04d0-8ef0-7dfc-b126-4640f0d7b628" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_019f13cb-b474-70ac-a169-f86e67f3ce1a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_019f04d0-8ef0-70c6-8503-fb28340de9c6" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_019f13cb-b474-70ac-a169-f86e67f3ce1a" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_019f04d0-8ef0-7e62-a645-1f4eff704a4a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue"/>
  </link:definitionLink>
</link:linkbase>
