v3.26.1
License and Collaborations (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2026
Dec. 31, 2025
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2026
Jun. 30, 2025
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2020
Dec. 31, 2017
License And Collaboration Agreements [Line Items]                    
Receivable from collaboration partners $ 36 $ 11     $ 36          
Other current liabilities 145 154     145          
Other noncurrent liabilities 124 135     124          
Taiho Collaboration Agreement                    
License And Collaboration Agreements [Line Items]                    
Milestone payments 30                  
Receivable from collaboration partners 36 10     36          
Other liabilities 35 44     35          
AstraZeneca Agreement                    
License And Collaboration Agreements [Line Items]                    
Milestone payments                 $ 24  
Development cost recorded within research and development expenses 4   $ 4   9 $ 8        
Other current liabilities 22       22          
Other noncurrent liabilities   12                
Taiho Pharmaceutical Co., Ltd | Taiho Agreement                    
License And Collaboration Agreements [Line Items]                    
Option period                   5 years
Non refundable and non creditable cash payments                   $ 35
Payment for option exercise   15                
Royalties payable term                   10 years
Reimbursement of research and development expense 6   8   12 17        
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum                    
License And Collaboration Agreements [Line Items]                    
Payment for option exercise                   $ 3
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum                    
License And Collaboration Agreements [Line Items]                    
Payment for option exercise                   15
Additional clinical and regulatory milestone payments receivable   172               130
Contingent milestone payments receivable   $ 145               $ 145
STAR-221 Development Activities | Taiho Collaboration Agreement                    
License And Collaboration Agreements [Line Items]                    
Milestone payments               $ 28    
STAR-121 Development Activities | Taiho Collaboration Agreement                    
License And Collaboration Agreements [Line Items]                    
Milestone payments             $ 26      
PRISM-1 Development Activities | Taiho Collaboration Agreement                    
License And Collaboration Agreements [Line Items]                    
Milestone payments       $ 19            
WuXi Biologics License Agreement | anti-PD-1                    
License And Collaboration Agreements [Line Items]                    
Development milestone expense 0   0   0 0        
WuXi Biologics License Agreement | anti-CD39                    
License And Collaboration Agreements [Line Items]                    
Development milestone expense 0   0   0 0        
WuXi Biologics License Agreement | Maximum | anti-PD-1                    
License And Collaboration Agreements [Line Items]                    
Clinical regulatory milestone payments         50          
Clinical, regulatory and commercialization milestone payments         375          
WuXi Biologics License Agreement | Maximum | anti-CD39                    
License And Collaboration Agreements [Line Items]                    
Additional clinical, regulatory and commercialization milestone payments         14          
Abmuno License Agreement                    
License And Collaboration Agreements [Line Items]                    
Development milestone expense $ 0   $ 0   0 $ 0        
Additional clinical, regulatory and commercialization milestone payments         $ 88