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  <xs:element id="mirm_BalanceSheetComponentsLineItems" abstract="true" name="BalanceSheetComponentsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mirm_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFour" abstract="false" name="FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AccruedSalesDeductionsAndOtherCurrent" abstract="false" name="AccruedSalesDeductionsAndOtherCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AccruedClinicalTrialsCurrent" abstract="false" name="AccruedClinicalTrialsCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AccruedContractManufacturingAndNonClinicalCostsCurrent" abstract="false" name="AccruedContractManufacturingAndNonClinicalCostsCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AccruedLossOnFirmPurchaseCommitmentsCurrent" abstract="false" name="AccruedLossOnFirmPurchaseCommitmentsCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AccruedMilestonePaymentCurrent" abstract="false" name="AccruedMilestonePaymentCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AccruedSalesDeductionAndOtherNoncurrentLiabilities" abstract="false" name="AccruedSalesDeductionAndOtherNoncurrentLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AccruedLossOnFirmPurchaseCommitmentsNoncurrent" abstract="false" name="AccruedLossOnFirmPurchaseCommitmentsNoncurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionsTable" abstract="true" name="AssetAcquisitionsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="mirm_NovartisPharmaAGMember" abstract="true" name="NovartisPharmaAGMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_EnthorinTherapeuticsLLCAndDartNeuroscienceLLCMember" abstract="true" name="EnthorinTherapeuticsLLCAndDartNeuroscienceLLCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_SanofiAventisDeutschlandGmbHMember" abstract="true" name="SanofiAventisDeutschlandGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_AssignedLicenseAgreementMember" abstract="true" name="AssignedLicenseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_AssetPurchaseAgreementMember" abstract="true" name="AssetPurchaseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_AssignmentAndLicenseAgreementMember" abstract="true" name="AssignmentAndLicenseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_AssignmentAndLicenceAgreementFDAMember" abstract="true" name="AssignmentAndLicenceAgreementFDAMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_AssignmentAndLicenceAgreementEuropeanMedicinesAgencyMember" abstract="true" name="AssignmentAndLicenceAgreementEuropeanMedicinesAgencyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_IncyteCorporationMember" abstract="true" name="IncyteCorporationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_BluejayAcquisitionMember" abstract="true" name="BluejayAcquisitionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_BluejayTherapeuticsInc.Member" abstract="true" name="BluejayTherapeuticsInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_BusinessCombinationContingentConsiderationMilestoneAxis" abstract="true" name="BusinessCombinationContingentConsiderationMilestoneAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="mirm_BusinessCombinationContingentConsiderationMilestoneDomain" abstract="true" name="BusinessCombinationContingentConsiderationMilestoneDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_FDAApprovalMember" abstract="true" name="FDAApprovalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_CommericalMilestonesMember" abstract="true" name="CommericalMilestonesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_BluejayEmployeeStockAwardsMember" abstract="true" name="BluejayEmployeeStockAwardsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_TravereTherapeuticsIncMember" abstract="true" name="TravereTherapeuticsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_ShireInternationalGmbHMember" abstract="true" name="ShireInternationalGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_ArrangementTypeAxis" abstract="true" name="ArrangementTypeAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="mirm_ArrangementTypeDomain" abstract="true" name="ArrangementTypeDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_VolixibatMember" abstract="true" name="VolixibatMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_AssetAcquisitionsLineItems" abstract="true" name="AssetAcquisitionsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mirm_AssetAcquisitionConsiderationTransferredUpfrontEquityConsiderationShares" abstract="false" name="AssetAcquisitionConsiderationTransferredUpfrontEquityConsiderationShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mirm_AssetAcquisitionConsiderationTransferredUpfrontCashConsideration" abstract="false" name="AssetAcquisitionConsiderationTransferredUpfrontCashConsideration" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionEquityConsiderationTransferredHoldbackShares" abstract="false" name="AssetAcquisitionEquityConsiderationTransferredHoldbackShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mirm_AssetAcquisitionCashConsiderationTransferredHoldbackAmount" abstract="false" name="AssetAcquisitionCashConsiderationTransferredHoldbackAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionCashConsiderationHoldbackAmountSubjectToFinalizationOfWorkingCapitalAdjustments" abstract="false" name="AssetAcquisitionCashConsiderationHoldbackAmountSubjectToFinalizationOfWorkingCapitalAdjustments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionNetAssetsAcquired" abstract="false" name="AssetAcquisitionNetAssetsAcquired" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionConsiderationTransferredCashConsideration" abstract="false" name="AssetAcquisitionConsiderationTransferredCashConsideration" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionCashAndCashEquivalents" abstract="false" name="AssetAcquisitionCashAndCashEquivalents" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_CollaborativeArrangementRightsAndObligationsMaximumAggregateDevelopmentMilestonePayments" abstract="false" name="CollaborativeArrangementRightsAndObligationsMaximumAggregateDevelopmentMilestonePayments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_CollaborativeArrangementRightsAndObligationsMaximumAggregateCommercialMilestonePayments" abstract="false" name="CollaborativeArrangementRightsAndObligationsMaximumAggregateCommercialMilestonePayments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_CollaborativeArrangementRightsAndObligationsContingentMilestonePayments" abstract="false" name="CollaborativeArrangementRightsAndObligationsContingentMilestonePayments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_PaymentsForAchievementOfContingentMilestones" abstract="false" name="PaymentsForAchievementOfContingentMilestones" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_CollaborativeArrangementRightsAndObligationsMaximumAggregateMilestonePayments" abstract="false" name="CollaborativeArrangementRightsAndObligationsMaximumAggregateMilestonePayments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_MilestonePaymentPayableUponAchievementOfProductSales" abstract="false" name="MilestonePaymentPayableUponAchievementOfProductSales" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_PaymentsForAchievementOfProductAndSalesMilestones" abstract="false" name="PaymentsForAchievementOfProductAndSalesMilestones" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_NumberOfProductCandidates" abstract="false" name="NumberOfProductCandidates" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="mirm_ClinicalDevelopmentAndRegulatoryMilestonePaymentsPayable" abstract="false" name="ClinicalDevelopmentAndRegulatoryMilestonePaymentsPayable" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_ClinicalDevelopmentAndRegulatoryMilestonePaymentsPayableUponRegulatoryApproval" abstract="false" name="ClinicalDevelopmentAndRegulatoryMilestonePaymentsPayableUponRegulatoryApproval" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_ClinicalDevelopmentAndRegulatoryMilestonePaymentsPayableUponCommercialization" abstract="false" name="ClinicalDevelopmentAndRegulatoryMilestonePaymentsPayableUponCommercialization" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_PaymentsAndAccrualsForAchievementOfVariousClinicalDevelopmentRegulatoryAndCommercialMilestones" abstract="false" name="PaymentsAndAccrualsForAchievementOfVariousClinicalDevelopmentRegulatoryAndCommercialMilestones" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_RoyaltyPaymentPeriodTerm" abstract="false" name="RoyaltyPaymentPeriodTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mirm_LicenseAgreementMilestoneAmountPayable" abstract="false" name="LicenseAgreementMilestoneAmountPayable" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_LicenseAgreementMilestoneAmountAccrued" abstract="false" name="LicenseAgreementMilestoneAmountAccrued" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_DevelopmentOrRegulatoryMilestonesIncurred" abstract="false" name="DevelopmentOrRegulatoryMilestonesIncurred" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_RoyaltyPaymentObligationsPeriod" abstract="false" name="RoyaltyPaymentObligationsPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mirm_AssetAcquisitionConsiderationTransferredEquityIndemnificationHoldback" abstract="false" name="AssetAcquisitionConsiderationTransferredEquityIndemnificationHoldback" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionConsiderationTransferredCashIndemnificationHoldback" abstract="false" name="AssetAcquisitionConsiderationTransferredCashIndemnificationHoldback" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionConsiderationTransferredDeferredConsideration" abstract="false" name="AssetAcquisitionConsiderationTransferredDeferredConsideration" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionConsiderationTransferredCashIndemnificationHoldbackAndWorkingCapital" abstract="false" name="AssetAcquisitionConsiderationTransferredCashIndemnificationHoldbackAndWorkingCapital" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionInProcessResearchAndDevelopment" abstract="false" name="AssetAcquisitionInProcessResearchAndDevelopment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionAssembledWorkforce" abstract="false" name="AssetAcquisitionAssembledWorkforce" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionPrepaidExpensesAndOtherCurrentAssets" abstract="false" name="AssetAcquisitionPrepaidExpensesAndOtherCurrentAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionOperatingLeaseRightOfUseAssets" abstract="false" name="AssetAcquisitionOperatingLeaseRightOfUseAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionOtherNonCurrentAssets" abstract="false" name="AssetAcquisitionOtherNonCurrentAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionAssetsAcquired" abstract="false" name="AssetAcquisitionAssetsAcquired" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionAccountsPayable" abstract="false" name="AssetAcquisitionAccountsPayable" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionAccruedExpensesAndOtherCurrentLiabilities" abstract="false" name="AssetAcquisitionAccruedExpensesAndOtherCurrentLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionOperatingLeaseLiabilitiesNoncurrent" abstract="false" name="AssetAcquisitionOperatingLeaseLiabilitiesNoncurrent" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionLiabilitiesAssumed" abstract="false" name="AssetAcquisitionLiabilitiesAssumed" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_AssetAcquisitionAssetsAcquiredAndLiabilitiesAssumedNet" abstract="false" name="AssetAcquisitionAssetsAcquiredAndLiabilitiesAssumedNet" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_TakedaMember" abstract="true" name="TakedaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_RegulatoryApprovalAndCommercializationMember" abstract="true" name="RegulatoryApprovalAndCommercializationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_CompanysTermToReceiveAnnualizedNetSales" abstract="false" name="CompanysTermToReceiveAnnualizedNetSales" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mirm_NewLeaseAgreementMember" abstract="true" name="NewLeaseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_AmendedOperatingLeaseAgreementMember" abstract="true" name="AmendedOperatingLeaseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_IncreaseDecreaseInOperatingLeaseRightOfUseAsset" abstract="false" name="IncreaseDecreaseInOperatingLeaseRightOfUseAsset" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" abstract="false" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_SeniorSubordinatedConvertibleNoteMember" abstract="true" name="SeniorSubordinatedConvertibleNoteMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_SeniorNotesDue2029Member" abstract="true" name="SeniorNotesDue2029Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_ConvertibleSeniorNotesDue2032Member" abstract="true" name="ConvertibleSeniorNotesDue2032Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_ConvertibleSeniorNotesDue2029Member" abstract="true" name="ConvertibleSeniorNotesDue2029Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_DebtInstrumentConvertibleTermsOfConversionAxis" abstract="true" name="DebtInstrumentConvertibleTermsOfConversionAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="mirm_DebtInstrumentConvertibleTermsOfConversionDomain" abstract="true" name="DebtInstrumentConvertibleTermsOfConversionDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_DebtConversionTermsOneMember" abstract="true" name="DebtConversionTermsOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_DebtConversionTermsTwoMember" abstract="true" name="DebtConversionTermsTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_DebtInstrumentsConvertibleRemainingDiscountAmortizationPeriod" abstract="false" name="DebtInstrumentsConvertibleRemainingDiscountAmortizationPeriod" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mirm_DebtInstrumentRedemptionPrincipalAmountOutstandingThreshold" abstract="false" name="DebtInstrumentRedemptionPrincipalAmountOutstandingThreshold" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_DebtInstrumentRedemptionPercentageOfPrincipalAmountUponCertainCustomaryEventsOfDefault" abstract="false" name="DebtInstrumentRedemptionPercentageOfPrincipalAmountUponCertainCustomaryEventsOfDefault" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mirm_PaymentForDebtExchangeAndRepurchase" abstract="false" name="PaymentForDebtExchangeAndRepurchase" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_DebtConversionConvertedInstrumentFairValue" abstract="false" name="DebtConversionConvertedInstrumentFairValue" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_PIPESharesMember" abstract="true" name="PIPESharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_WarrantSharesMember" abstract="true" name="WarrantSharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_PreFundedWarrantMember" abstract="true" name="PreFundedWarrantMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_SalesAgreementMember" abstract="true" name="SalesAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_EstimatedOfferingExpenses" abstract="false" name="EstimatedOfferingExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_OwnershipPercentageThreshold" abstract="false" name="OwnershipPercentageThreshold" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mirm_OwnershipPercentageMaximumThreshold" abstract="false" name="OwnershipPercentageMaximumThreshold" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mirm_ClassOfWarrantOrRightExercised" abstract="false" name="ClassOfWarrantOrRightExercised" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mirm_PercentageOfGrossProceeds" abstract="false" name="PercentageOfGrossProceeds" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mirm_CommonStockOptionsRestrictedStockUnitsAndPerformanceStockUnitsIssuedAndOutstandingMember" abstract="true" name="CommonStockOptionsRestrictedStockUnitsAndPerformanceStockUnitsIssuedAndOutstandingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_FutureStockAwardsOrOptionGrantsMember" abstract="true" name="FutureStockAwardsOrOptionGrantsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_EmployeeStockPurchasePlanMember" abstract="true" name="EmployeeStockPurchasePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_HoldbackSharesInConnectionWithTheAssetAcquisitionMember" abstract="true" name="HoldbackSharesInConnectionWithTheAssetAcquisitionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_PerformanceStockUnitsMember" abstract="true" name="PerformanceStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_NumberOfReportableSegmentsNotDisclosedFlag" abstract="false" name="NumberOfReportableSegmentsNotDisclosedFlag" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mirm_ReportableSegmentMember" abstract="true" name="ReportableSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mirm_CommercializationAndMedicalAffairsExpensesExcludingStockBasedCompensation" abstract="false" name="CommercializationAndMedicalAffairsExpensesExcludingStockBasedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_ResearchAndDevelopmentExpensesExcludingStockBasedCompensation" abstract="false" name="ResearchAndDevelopmentExpensesExcludingStockBasedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mirm_LossContingencyPeriodOfFinalRegulatoryStay" abstract="false" name="LossContingencyPeriodOfFinalRegulatoryStay" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
</xs:schema>
