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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Cash flows from operating activities:    
Net loss $ (82,480) $ (60,452)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 1,646 1,980
Stock‑based compensation expense 9,894 10,135
Amortization/(accretion) of marketable securities (998) (2,299)
Changes in operating assets and liabilities:    
Collaboration receivable 361 2,500
Prepaid expenses and other current assets (164) 2,407
Right-of-use assets, operating leases 3,410 5,439
Other non-current assets (48) 85
Accounts payable 1,457 (2,231)
Accrued expenses and other current liabilities (4,679) (1,145)
Income tax payable 0 (667)
Operating lease liabilities (2,388) (4,464)
Deferred revenue (169) (19,284)
Net cash used in operating activities (74,158) (67,996)
Cash flows from investing activities:    
Purchases of property and equipment (55) (1,419)
Purchases of marketable securities (15,750) (96,574)
Maturities of marketable securities 97,741 136,573
Net cash provided by investing activities 81,936 38,580
Cash flows from financing activities:    
Proceeds from exercise of stock options 130 370
Proceeds from issuance of common stock under the employee stock purchase plan 320 317
Net cash provided by financing activities 450 687
Net increase (decrease) in cash, cash equivalents and restricted cash 8,228 (28,729)
Cash, cash equivalents, and restricted cash at beginning of period 94,344 105,161
Cash, cash equivalents, and restricted cash at end of period 102,572 76,432
Supplemental cash flow disclosures:    
Vesting of options early exercised subject to repurchase $ 0 $ 14