v3.26.1
Segment Information - Operating Segment Information (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Mar. 31, 2026
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2026
Jun. 30, 2025
Segment Reporting [Line Items]            
Collaboration revenue $ 898   $ 1,950   $ 1,773 $ 22,508
Total research and development expenses 35,369   37,877   68,423 69,951
General and administrative expenses 10,492   10,922   20,616 21,196
Interest and other income 2,235   3,924   4,859 8,365
Provision for (benefit from) income taxes 35   178   73 178
Net (loss) income (42,763) $ (39,717) (43,103) $ (17,349) (82,480) (60,452)
Reportable Segment            
Segment Reporting [Line Items]            
Collaboration revenue 898   1,950   1,773 22,508
Total research and development expenses 35,369   37,877   68,423 69,951
General and administrative expenses 10,492   10,922   20,616 21,196
Interest and other income 2,235   3,924   4,859 8,365
Provision for (benefit from) income taxes 35   178   73 178
Net (loss) income (42,763)   (43,103)   (82,480) (60,452)
Reportable Segment | ENTR-601-44            
Segment Reporting [Line Items]            
Total research and development expenses 7,213   4,446   11,968 9,180
Reportable Segment | ENTR-601-45            
Segment Reporting [Line Items]            
Total research and development expenses 3,029   4,576   6,631 7,435
Reportable Segment | ENTR-601-50            
Segment Reporting [Line Items]            
Total research and development expenses 1,727   2,040   3,096 2,732
Reportable Segment | ENTR-601-51            
Segment Reporting [Line Items]            
Total research and development expenses 1,260   2,855   3,597 3,681
Reportable Segment | DMD franchise-wide            
Segment Reporting [Line Items]            
Total research and development expenses 3,486   1,712   5,225 1,712
Reportable Segment | Collaboration services            
Segment Reporting [Line Items]            
Total research and development expenses 301   527   535 1,403
Reportable Segment | Ocular programs            
Segment Reporting [Line Items]            
Total research and development expenses 649   542   1,110 812
Reportable Segment | Other preclinical and discovery            
Segment Reporting [Line Items]            
Total research and development expenses 406   682   1,006 1,669
Reportable Segment | Personnel related (including stock-based compensation)            
Segment Reporting [Line Items]            
Total research and development expenses 11,795   13,231   23,837 25,987
Reportable Segment | Facility related and other            
Segment Reporting [Line Items]            
Total research and development expenses $ 5,503   $ 7,266   $ 11,418 $ 15,340