| Summary of Reconciles Reported Revenues to Net (Loss) Income under Significant Expense Principle |
The following table reconciles reported revenues to net (loss) income under the significant expense principle for the three and six months ended June 30, 2026 and 2025 (in thousands):
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For the Three Months Ended June 30, |
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For the Six Months Ended June 30, |
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2026 |
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2025 |
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2026 |
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2025 |
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Collaboration Revenue |
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$ |
— |
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$ |
— |
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$ |
20,000 |
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$ |
— |
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Research and Development Expenses: |
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RAP-219 program external expenses |
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34,088 |
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9,685 |
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49,909 |
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17,648 |
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Preclinical programs external expenses |
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4,870 |
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4,722 |
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9,159 |
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7,968 |
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R&D personnel-related costs (including stock-based compensation) |
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10,637 |
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6,666 |
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21,277 |
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13,452 |
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Other costs |
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1,819 |
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1,607 |
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3,785 |
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3,184 |
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Selling, General and Administrative Expenses: |
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G&A personnel-related costs (including stock-based compensation) |
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7,085 |
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5,045 |
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14,068 |
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10,004 |
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Professional and consulting costs |
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1,463 |
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920 |
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5,135 |
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2,584 |
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Facility related and other |
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844 |
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851 |
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1,688 |
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1,764 |
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Loss from operations |
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$ |
(60,806 |
) |
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$ |
(29,496 |
) |
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$ |
(85,021 |
) |
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$ |
(56,604 |
) |
Interest income |
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4,191 |
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2,764 |
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8,549 |
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5,809 |
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Net loss |
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$ |
(56,615 |
) |
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$ |
(26,732 |
) |
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$ |
(76,472 |
) |
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$ |
(50,795 |
) |
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