Accrued Expenses - Summary of Accrued Expenses (Detail) - USD ($) $ in Thousands |
Jun. 30, 2026 |
Dec. 31, 2025 |
|---|---|---|
| Payables and Accruals [Abstract] | ||
| Product revenue related reserves | $ 118,639 | $ 117,518 |
| Accrued contract manufacturing costs | 41,256 | 92,281 |
| Accrued employee compensation costs | 40,972 | 58,607 |
| Accrued litigation contingency charge | 39,000 | 0 |
| Accrued professional fees | 20,874 | 17,840 |
| Accrued interest expense | 15,847 | 20,714 |
| Accrued clinical and pre-clinical costs | 15,308 | 18,894 |
| Accrued income taxes | 9,309 | 4,755 |
| Accrued royalties | 10,200 | 10,863 |
| Accrued clinical collaboration costs | 5,155 | 10,222 |
| Accrued milestone costs | 3,200 | 1,000 |
| Other | 5,472 | 6,965 |
| Total accrued expenses | $ 325,232 | $ 359,659 |
| X | ||||||||||
- Definition Accrued clinical and preclinical costs current. No definition available.
|
| X | ||||||||||
- Definition Accrued Clinical Collaboration Costs No definition available.
|
| X | ||||||||||
- Definition Accrued contract manufacturing expense current. No definition available.
|
| X | ||||||||||
- Definition Accrued Litigation Settlement No definition available.
|
| X | ||||||||||
- Definition Accrued milestone costs No definition available.
|
| X | ||||||||||
- Definition Accrued product revenue related reserve current. No definition available.
|
| X | ||||||||||
- Definition Carrying amount as of the balance sheet date of the unpaid sum of the known and estimated amounts payable to satisfy all domestic and foreign income tax obligations due. This amount is the total of current and noncurrent accrued income taxes. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
|
| X | ||||||||||
- Definition Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
|
| X | ||||||||||
- Definition Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
|
| X | ||||||||||
- Definition Carrying value as of the balance sheet date of obligations incurred through that date and payable for royalties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
|
| X | ||||||||||
- Definition Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
|
| X | ||||||||||
- Definition Carrying value as of the balance sheet date of [accrued] interest payable on all forms of debt, including trade payables, that has been incurred and is unpaid. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://www.xbrl.org/2003/role/exampleRef
|
| X | ||||||||||
- Definition Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
|
| X | ||||||||||
- References No definition available.
|