Liabilities for Sales of Future Royalties - Schedule of Key Terms and Activity of Sales of Future Royalties (Details) $ in Millions	6 Months Ended
	Jun. 30, 2026 USD ($)
2025 OMERS Agreement
Liability For Sale Of Future Royalties [Line Items]
Agreement counterparty	OMERS
Contract execution date	2025-11
Payment from sale of future royalties	$ 400
Royalties transaction costs net	$ 8
Royalties agreement territories	U.S. and Canada
Percentage of royalties sold	25.00%
Royalty start date	Jan. 01, 2028
Royalty purchase agreement cap amount	$ 620
Royalties Earned From Inception	$ 0
Effective annual interest rate	9.20%
2022 OMERS Agreement
Liability For Sale Of Future Royalties [Line Items]
Agreement counterparty	OMERS
Contract execution date	2022-07
Payment from sale of future royalties	$ 500
Royalties transaction costs net	$ 9
Royalties agreement territories	U.S. and Canada
Percentage of royalties sold	30.00%
Royalty start date	Apr. 01, 2023
Royalty purchase agreement cap amount	$ 725
Royalties Earned From Inception	$ 246
Effective annual interest rate	7.30%
RPI Finance Trust (RPI)
Liability For Sale Of Future Royalties [Line Items]
Agreement counterparty	RPI
Contract execution date	2019-12
Payment from sale of future royalties	$ 320
Royalties transaction costs net	$ 6
Royalties agreement territories	EU, U.K., and Switzerland
Percentage of royalties sold	100.00%
Royalty start date	Jan. 01, 2020
Royalty purchase agreement cap amount	$ 608
Royalty purchase agreement cap aggregate payment	800
Royalties Earned From Inception	$ 144
Effective annual interest rate	5.50%