<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019fb9a4-a8a0-72f2-a9a6-392c0c541011,g:adda7e5f-335a-43d7-a79f-5be3589d8811-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.uplandsoftware.com/role/Cover" xlink:type="simple" xlink:href="upld-20260731.xsd#Cover"/>
  <link:presentationLink xlink:role="http://www.uplandsoftware.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_019fb9a4-a8a0-76cd-b5b0-0b2373b48404" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationTable_019fb9a4-a8a0-76c6-896e-d20929e46022" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentInformationTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019fb9a4-a8a0-76cd-b5b0-0b2373b48404" xlink:to="loc_dei_DocumentInformationTable_019fb9a4-a8a0-76c6-896e-d20929e46022" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_019fb9a4-a8a0-7020-97d1-f8b977945d6c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationTable_019fb9a4-a8a0-76c6-896e-d20929e46022" xlink:to="loc_us-gaap_StatementClassOfStockAxis_019fb9a4-a8a0-7020-97d1-f8b977945d6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_019fb9a4-a8a0-7377-9f32-3904e474b5da" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_019fb9a4-a8a0-7020-97d1-f8b977945d6c" xlink:to="loc_us-gaap_ClassOfStockDomain_019fb9a4-a8a0-7377-9f32-3904e474b5da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_upld_CommonStockParValue00001PerShareMember_019fb9a4-a8a0-70cc-8a4e-5a7e96319987" xlink:href="upld-20260731.xsd#upld_CommonStockParValue00001PerShareMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_019fb9a4-a8a0-7377-9f32-3904e474b5da" xlink:to="loc_upld_CommonStockParValue00001PerShareMember_019fb9a4-a8a0-70cc-8a4e-5a7e96319987" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_upld_PreferredStockPurchaseRightsMember_019fb9a4-a8a0-7d87-81f5-2808ccdc41f7" xlink:href="upld-20260731.xsd#upld_PreferredStockPurchaseRightsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_019fb9a4-a8a0-7377-9f32-3904e474b5da" xlink:to="loc_upld_PreferredStockPurchaseRightsMember_019fb9a4-a8a0-7d87-81f5-2808ccdc41f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentInformationLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationTable_019fb9a4-a8a0-76c6-896e-d20929e46022" xlink:to="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_019fb9a4-a8a0-7f61-949c-f3f1af7ce6ba" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_DocumentType_019fb9a4-a8a0-7f61-949c-f3f1af7ce6ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_019fb9a4-a8a0-7bee-a0d8-071ebdcc3be5" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_DocumentPeriodEndDate_019fb9a4-a8a0-7bee-a0d8-071ebdcc3be5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_019fb9a4-a8a0-7395-94bb-b977ea9477f9" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityRegistrantName_019fb9a4-a8a0-7395-94bb-b977ea9477f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_019fb9a4-a8a0-77ba-a467-b3a0fccb9870" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityIncorporationStateCountryCode_019fb9a4-a8a0-77ba-a467-b3a0fccb9870" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_019fb9a4-a8a0-7b50-8ff9-dce9610e5674" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityFileNumber_019fb9a4-a8a0-7b50-8ff9-dce9610e5674" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_019fb9a4-a8a0-783e-ada8-d743b4ab4400" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityTaxIdentificationNumber_019fb9a4-a8a0-783e-ada8-d743b4ab4400" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_019fb9a4-a8a0-71a6-be9f-e33a84436cdf" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityAddressAddressLine1_019fb9a4-a8a0-71a6-be9f-e33a84436cdf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_019fb9a4-a8a0-7369-822e-0fb3ae4b6038" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityAddressCityOrTown_019fb9a4-a8a0-7369-822e-0fb3ae4b6038" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_019fb9a4-a8a0-7fb7-9f89-c231298fdf24" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityAddressStateOrProvince_019fb9a4-a8a0-7fb7-9f89-c231298fdf24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_019fb9a4-a8a0-74e5-8579-6c110c4bcde9" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityAddressPostalZipCode_019fb9a4-a8a0-74e5-8579-6c110c4bcde9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_019fb9a4-a8a0-7bce-a0f9-c104ec3ef88a" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_CityAreaCode_019fb9a4-a8a0-7bce-a0f9-c104ec3ef88a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_019fb9a4-a8a0-7b01-bffe-82180aad05c1" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_LocalPhoneNumber_019fb9a4-a8a0-7b01-bffe-82180aad05c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_019fb9a4-a8a0-7645-b3ce-145316180eea" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_WrittenCommunications_019fb9a4-a8a0-7645-b3ce-145316180eea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_019fb9a4-a8a0-708d-8181-a8a4f8c7d4dd" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_SolicitingMaterial_019fb9a4-a8a0-708d-8181-a8a4f8c7d4dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_019fb9a4-a8a0-75ac-8e05-2049bd7542e6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_PreCommencementTenderOffer_019fb9a4-a8a0-75ac-8e05-2049bd7542e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_019fb9a4-a8a0-7e6b-86aa-fe2caa28ca73" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_019fb9a4-a8a0-7e6b-86aa-fe2caa28ca73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_019fb9a4-a8a0-7c4c-8b89-736e95299da3" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_Security12bTitle_019fb9a4-a8a0-7c4c-8b89-736e95299da3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_019fb9a4-a8a0-781b-ae70-9e59ca06c67e" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_TradingSymbol_019fb9a4-a8a0-781b-ae70-9e59ca06c67e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_019fb9a4-a8a0-76fa-b961-d9b077121e0a" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_SecurityExchangeName_019fb9a4-a8a0-76fa-b961-d9b077121e0a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_NoTradingSymbolFlag_019fb9a4-a8a0-742b-9b37-f22d3b4bb4be" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_NoTradingSymbolFlag"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_NoTradingSymbolFlag_019fb9a4-a8a0-742b-9b37-f22d3b4bb4be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_019fb9a4-a8a0-73c8-adce-f646034d5193" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityEmergingGrowthCompany_019fb9a4-a8a0-73c8-adce-f646034d5193" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_019fb9a4-a8a0-72c8-803d-625dec2c00a6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_EntityCentralIndexKey_019fb9a4-a8a0-72c8-803d-625dec2c00a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_019fb9a4-a8a0-7b5f-b363-c9662fa436d8" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_DocumentInformationLineItems_019fb9a4-a8a0-760b-9654-bc38e62abd16" xlink:to="loc_dei_AmendmentFlag_019fb9a4-a8a0-7b5f-b363-c9662fa436d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
