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Nature of Business (Details) - USD ($)		6 Months Ended
Nature of Business (Details) - USD ($)	May 26, 2026	Jun. 30, 2026	Jun. 30, 2025	Dec. 31, 2025	Mar. 31, 2025	May 31, 2021
Liquidity
Aggregate net proceeds		$ 1,200,000,000
Cash, cash equivalents and marketable securities		211,600,000
Proceeds from issuance of common stock		117,499,000	$ 8,619,000
Retained Earnings (Accumulated Deficit)		$ 1,671,715,000		$ 1,628,503,000
Common Stock Warrants
Liquidity
Net proceeds	$ 116,900,000
Proceeds from issuance of common stock	$ 87,300,000
May 2026 Offering
Liquidity
Number of common stock issued (in shares)	55,555,556
May 2026 Offering \| Pre Funded Warrants
Liquidity
Class of warrant or right, number of securities called by warrants or rights	55,555,556
Proceeds from warrant exercises	$ 192,500,000
At The Market Offering
Liquidity
Number of common stock issued (in shares)		14,327,365
Sales agreement amount of aggregate sale proceeds of common stock agreed to be issued					$ 150,000,000.0	$ 300,000,000.0
Proceeds from issuance of common stock		$ 43,900,000
Sales agreement, amount of aggregate sale proceeds of common stock available		$ 106,100,000