exfilingfees

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Fees to be paid

Equity

Ordinary Shares, nominal value GBP0.008 per share

457(r)

$0.00013810

Fees to be paid

Equity

American Depositary Shares representing Ordinary Shares, nominal value GBP per share

457(r)

$0.00013810

Fees to be paid

Debt

Debt Securities

457(r)

$0.00013810

Fees to be paid

Other

Warrants

457(r)

$0.00013810

Fees to be paid

Other

Units

457(r)

$0.00013810

Fees Previously Paid

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Carry Forward Securities

Equity

American Depositary Shares representing Ordinary Shares, nominal value GBP 0.008 per share

415(a)(6)

10,649,700

—

$96,486,282.00

—

S-3

333-274436

9/18/2023

$10,632.79000000

Total Offering Amounts

$96,486,282.00

$0.00

Total Fees Previously Paid

$0.00

Total Fee Offsets

$0.00

Net Fee Due

$0.00

(1)In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended, the Registrant is deferring payment of all registration fees, other than the registration fee due in connection with 10,649,700 American Depositary Shares, or ADSs, being registered for resale pursuant to the prospectus included in this Registration Statement, and will pay the registration fees subsequently in advance or on a "pay-as-you-go" basis. The Registrant will calculate the registration fee applicable to an offer of securities pursuant to this Registration Statement based on the fee payment rate in effect on the date of such fee payment.

(6)Pursuant to Rule 415(a)(6) under the Securities Act, 10,649,700 ADSs registered hereunder are unsold securities previously covered by the Registrant’s registration statement on Form S-3 (File No. 333-274436), which was originally filed with the Securities and Exchange Commission on September 8, 2023 and declared effective on September 18, 2023 (the “Prior Registration Statement”). Pursuant to Rule 415(a)(6) under the Securities Act, the $10,632.79 filing fee previously paid at the time of the filing of the Prior Registration Statement in connection with such unsold securities will continue to be applied to such unsold securities. Pursuant to Rule 415(a)(6) under the Securities Act of 1933, the offering of unsold securities under the Prior Registration Statement will be deemed terminated as of the date of effectiveness of this Registration Statement. Estimated in accordance with Rule 457(c) solely for purposes of calculating the registration fee on the basis of the average of the high and low prices of the Registrant’s ADSs as reported on the Nasdaq Capital Market on July 29, 2026.

Registrant or Filer Name

Form or Filing Type

File Number

Initial Filing Date

Filing Date

Fee Offset Claimed

Security Type Associated with Fee Offset Claimed

Security Title Associated with Fee Offset Claimed

Unsold Securities Associated with Fee Offset Claimed

Unsold Aggregate Offering Amount Associated with Fee Offset Claimed

Fee Paid with Fee Offset Source

Rules 457(b) and 0-11(a)(2)

Fee Offset Claims

Fees to be paid

Rule 457(p)

Fees Offset Claims

Fee Offset Sources

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A